From 6df0435f6526c173a1181ab95aad211f4ee04091 Mon Sep 17 00:00:00 2001 From: Jiarui Li Date: Fri, 26 Jun 2026 16:25:36 +0800 Subject: [PATCH] Refactor DeepHealth indices around disease expression --- build_icd10_organ_label_mapping.py | 137 --- build_organ_involvement_label_mapping.py | 157 +++ build_uk_hfrs_label_mapping.py | 215 ++++ burden_index.py | 364 ++----- burden_index_method.tex | 619 ++--------- burden_index_method_zh.tex | 517 ++------- cihi_hfrm_label_mapping.csv | 306 ------ compute_burden_index_landmarks.py | 1120 ------------------- compute_deephealth_indices_landmarks.py | 717 ++++++++++++ icd10_organ_label_mapping.csv | 1257 ---------------------- organ_involvement_label_mapping.csv | 1257 ++++++++++++++++++++++ plot_burden_index_trajectories.py | 258 ----- plot_deephealth_index_trajectories.py | 214 ++++ uk_hfrs_label_mapping.csv | 1257 ++++++++++++++++++++++ uk_hfrs_missing_label_codes.csv | 53 + 15 files changed, 4168 insertions(+), 4280 deletions(-) delete mode 100644 build_icd10_organ_label_mapping.py create mode 100644 build_organ_involvement_label_mapping.py create mode 100644 build_uk_hfrs_label_mapping.py delete mode 100644 cihi_hfrm_label_mapping.csv delete mode 100644 compute_burden_index_landmarks.py create mode 100644 compute_deephealth_indices_landmarks.py delete mode 100644 icd10_organ_label_mapping.csv create mode 100644 organ_involvement_label_mapping.csv delete mode 100644 plot_burden_index_trajectories.py create mode 100644 plot_deephealth_index_trajectories.py create mode 100644 uk_hfrs_label_mapping.csv create mode 100644 uk_hfrs_missing_label_codes.csv diff --git a/build_icd10_organ_label_mapping.py b/build_icd10_organ_label_mapping.py deleted file mode 100644 index 0b3745b..0000000 --- a/build_icd10_organ_label_mapping.py +++ /dev/null @@ -1,137 +0,0 @@ -from __future__ import annotations - -import csv -import re -from pathlib import Path - - -LABELS = Path("labels.csv") -OUT = Path("icd10_organ_label_mapping.csv") - - -ICD10_CHAPTERS = [ - ("A00", "B99", "I", "Certain infectious and parasitic diseases", "infection_immune"), - ("C00", "D48", "II", "Neoplasms", "neoplasm"), - ("D50", "D89", "III", "Diseases of the blood and immune mechanism", "hematologic_immune"), - ("E00", "E90", "IV", "Endocrine, nutritional and metabolic diseases", "metabolic_endocrine"), - ("F00", "F99", "V", "Mental and behavioural disorders", "mental_behavioral"), - ("G00", "G99", "VI", "Diseases of the nervous system", "neurologic"), - ("H00", "H59", "VII", "Diseases of the eye and adnexa", "sensory_eye"), - ("H60", "H95", "VIII", "Diseases of the ear and mastoid process", "sensory_ear"), - ("I00", "I99", "IX", "Diseases of the circulatory system", "cardiovascular"), - ("J00", "J99", "X", "Diseases of the respiratory system", "respiratory"), - ("K00", "K93", "XI", "Diseases of the digestive system", "digestive_liver"), - ("L00", "L99", "XII", "Diseases of the skin and subcutaneous tissue", "skin_soft_tissue"), - ("M00", "M99", "XIII", "Diseases of the musculoskeletal system", "musculoskeletal"), - ("N00", "N99", "XIV", "Diseases of the genitourinary system", "genitourinary_renal"), - ("O00", "O99", "XV", "Pregnancy, childbirth and puerperium", "pregnancy_reproductive"), - ("P00", "P96", "XVI", "Certain conditions originating in the perinatal period", "perinatal"), - ("Q00", "Q99", "XVII", "Congenital malformations", "congenital"), - ("R00", "R99", "XVIII", "Symptoms, signs and abnormal findings", "symptoms_findings"), - ("S00", "T98", "XIX", "Injury, poisoning and external causes", "injury_poisoning"), - ("V01", "Y98", "XX", "External causes of morbidity and mortality", "external_causes"), - ("Z00", "Z99", "XXI", "Factors influencing health status", "health_status_factors"), - ("U00", "U99", "XXII", "Codes for special purposes", "special_purpose"), -] - - -ORGAN_OVERRIDES = [ - ("I60", "I69", "brain_vascular"), - ("N17", "N19", "kidney"), - ("K70", "K77", "liver"), - ("E10", "E14", "diabetes_metabolic"), - ("F00", "F09", "cognition_neuropsychiatric"), - ("G30", "G32", "cognition_neurodegenerative"), - ("H53", "H54", "sensory_vision"), - ("H90", "H91", "sensory_hearing"), - ("J40", "J47", "chronic_respiratory"), - ("C00", "D48", "neoplasm"), -] - - -def _code_key(code: str) -> tuple[str, int, str]: - code = code.strip().upper() - match = re.match(r"^([A-Z])(\d{2})(?:\.?([A-Z0-9]+))?", code) - if not match: - raise ValueError(f"Invalid ICD-10 code: {code!r}") - letter, number, suffix = match.groups() - return letter, int(number), suffix or "" - - -def _code_in_range(code: str, start: str, end: str) -> bool: - c_letter, c_num, _ = _code_key(code) - s_letter, s_num, _ = _code_key(start) - e_letter, e_num, _ = _code_key(end) - if s_letter == e_letter: - return c_letter == s_letter and s_num <= c_num <= e_num - return (s_letter < c_letter < e_letter) or ( - c_letter == s_letter and c_num >= s_num - ) or (c_letter == e_letter and c_num <= e_num) - - -def _chapter_for_code(code: str) -> tuple[str, str, str]: - if not re.match(r"^[A-Z]\d{2}", code.strip().upper()): - return "", "", "unmapped" - for start, end, chapter_id, chapter_name, default_system in ICD10_CHAPTERS: - if _code_in_range(code, start, end): - return chapter_id, chapter_name, default_system - return "", "", "unmapped" - - -def _organ_system_for_code(code: str, default_system: str) -> str: - if default_system == "unmapped": - return "unmapped" - for start, end, organ_system in ORGAN_OVERRIDES: - if _code_in_range(code, start, end): - return organ_system - return default_system - - -def main() -> None: - rows = [] - with LABELS.open(encoding="utf-8") as f: - for i, line in enumerate(f): - line = line.strip() - if not line: - continue - parts = line.split(maxsplit=1) - code = parts[0].strip().upper() - name = parts[1].strip() if len(parts) > 1 else "" - chapter_id, chapter_name, default_system = _chapter_for_code(code) - organ_system = _organ_system_for_code(code, default_system) - rows.append( - { - "token_id": i + 3, - "label_code": code, - "label_name": name, - "icd10_chapter_id": chapter_id, - "icd10_chapter_name": chapter_name, - "organ_system": organ_system, - "organ_weight": 1.0 if organ_system != "unmapped" else 0.0, - "match_source": "icd10_chapter_range", - } - ) - - fieldnames = [ - "token_id", - "label_code", - "label_name", - "icd10_chapter_id", - "icd10_chapter_name", - "organ_system", - "organ_weight", - "match_source", - ] - with OUT.open("w", newline="", encoding="utf-8-sig") as f: - writer = csv.DictWriter(f, fieldnames=fieldnames) - writer.writeheader() - writer.writerows(rows) - - print(f"labels: {len(rows)}") - print(f"output: {OUT}") - systems = sorted({row["organ_system"] for row in rows}) - print("organ_systems:", ", ".join(systems)) - - -if __name__ == "__main__": - main() diff --git a/build_organ_involvement_label_mapping.py b/build_organ_involvement_label_mapping.py new file mode 100644 index 0000000..a23f89c --- /dev/null +++ b/build_organ_involvement_label_mapping.py @@ -0,0 +1,157 @@ +from __future__ import annotations + +import csv +import re +from pathlib import Path + + +LABELS = Path("labels.csv") +OUT = Path("organ_involvement_label_mapping.csv") + + +ORGANS = [ + "brain_neurologic", + "heart", + "artery_vascular", + "immune", + "intestine_digestive", + "kidney", + "liver", + "lung", + "muscle_musculoskeletal", + "pancreas_endocrine", + "adipose_metabolic", + "female_reproductive", + "male_reproductive", + "neoplasm", +] + + +def _code_key(code: str) -> tuple[str, int, str]: + code = code.strip().upper() + match = re.match(r"^([A-Z])(\d{2})(?:\.?([A-Z0-9]+))?", code) + if not match: + raise ValueError(f"Invalid ICD-10 code: {code!r}") + letter, number, suffix = match.groups() + return letter, int(number), suffix or "" + + +def _in_range(code: str, start: str, end: str) -> bool: + c_letter, c_num, _ = _code_key(code) + s_letter, s_num, _ = _code_key(start) + e_letter, e_num, _ = _code_key(end) + if s_letter == e_letter: + return c_letter == s_letter and s_num <= c_num <= e_num + return ( + (s_letter < c_letter < e_letter) + or (c_letter == s_letter and c_num >= s_num) + or (c_letter == e_letter and c_num <= e_num) + ) + + +def _matches_any(code: str, ranges: list[tuple[str, str]]) -> bool: + return any(_in_range(code, start, end) for start, end in ranges) + + +def organ_for_icd10(code: str) -> tuple[str, str]: + code = code.strip().upper() + if not re.match(r"^[A-Z]\d{2}", code): + return "", "unmapped_non_icd10" + + if _matches_any(code, [("C00", "D48")]): + return "neoplasm", "neoplasm_c00_d48" + + if _matches_any(code, [("F00", "F09"), ("G00", "G99"), ("I60", "I69")]): + return "brain_neurologic", "f00_f09_g00_g99_i60_i69" + + if _matches_any(code, [("I00", "I09"), ("I20", "I52")]): + return "heart", "i00_i09_i20_i52" + + if _matches_any(code, [("I10", "I15"), ("I70", "I89"), ("I95", "I99")]): + return "artery_vascular", "i10_i15_i70_i89_i95_i99" + + if _matches_any(code, [("A00", "B99"), ("D50", "D89")]): + return "immune", "a00_b99_d50_d89" + + if _matches_any(code, [("J00", "J99")]): + return "lung", "j00_j99" + + if _matches_any(code, [("K70", "K77")]): + return "liver", "k70_k77" + + if _matches_any(code, [("K85", "K86"), ("E10", "E16")]): + return "pancreas_endocrine", "k85_k86_e10_e16" + + if _matches_any(code, [("K00", "K69"), ("K78", "K84"), ("K87", "K93")]): + return "intestine_digestive", "k00_k69_k78_k84_k87_k93" + + if _matches_any(code, [("N00", "N39")]): + return "kidney", "n00_n39" + + if _matches_any(code, [("N70", "N98"), ("O00", "O99")]): + return "female_reproductive", "n70_n98_o00_o99" + + if _matches_any(code, [("N40", "N53")]): + return "male_reproductive", "n40_n53" + + if _matches_any(code, [("M00", "M99")]): + return "muscle_musculoskeletal", "m00_m99" + + if _matches_any(code, [("E00", "E09"), ("E17", "E90")]): + return "adipose_metabolic", "e00_e09_e17_e90" + + return "", "unmapped_no_organ_rule" + + +def main() -> None: + rows = [] + with LABELS.open(encoding="utf-8") as f: + for i, line in enumerate(f): + line = line.strip() + if not line: + continue + parts = line.split(maxsplit=1) + code = parts[0].strip().upper() + name = parts[1].strip() if len(parts) > 1 else "" + organ_id, match_source = organ_for_icd10(code) + rows.append( + { + "token_id": i + 3, + "label_code": code, + "label_name": name, + "organ_id": organ_id, + "organ_label": organ_id, + "organ_weight": 1.0 if organ_id else 0.0, + "match_source": match_source, + "mapping_source": ( + "organ-age-inspired clinical systems based on " + "Oh et al. Nature 2023; single-label ICD-10 rules" + ), + } + ) + + fieldnames = [ + "token_id", + "label_code", + "label_name", + "organ_id", + "organ_label", + "organ_weight", + "match_source", + "mapping_source", + ] + with OUT.open("w", newline="", encoding="utf-8-sig") as f: + writer = csv.DictWriter(f, fieldnames=fieldnames) + writer.writeheader() + writer.writerows(rows) + + mapped = [row for row in rows if row["organ_id"]] + print(f"labels: {len(rows)}") + print(f"mapped_labels: {len(mapped)}") + print(f"unmapped_labels: {len(rows) - len(mapped)}") + print(f"organs: {', '.join(ORGANS)}") + print(f"output: {OUT}") + + +if __name__ == "__main__": + main() diff --git a/build_uk_hfrs_label_mapping.py b/build_uk_hfrs_label_mapping.py new file mode 100644 index 0000000..0fb62c9 --- /dev/null +++ b/build_uk_hfrs_label_mapping.py @@ -0,0 +1,215 @@ +from __future__ import annotations + +import csv +from pathlib import Path + + +LABELS = Path("labels.csv") +OUT = Path("uk_hfrs_label_mapping.csv") +MISSING_OUT = Path("uk_hfrs_missing_label_codes.csv") + + +# Source: Gilbert T, Neuburger J, Kraindler J, et al. Development and +# validation of a Hospital Frailty Risk Score focusing on older people in +# acute care settings using electronic hospital records. Lancet. 2018. +# Supplementary appendix, Table A2. +UK_HFRS_WEIGHTS = { + "F00": 7.1, + "G81": 4.4, + "G30": 4.0, + "I69": 3.7, + "R29": 3.6, + "N39": 3.2, + "F05": 3.2, + "W19": 3.2, + "S00": 3.2, + "R31": 3.0, + "B96": 2.9, + "R41": 2.7, + "R26": 2.6, + "I67": 2.6, + "R56": 2.6, + "R40": 2.5, + "T83": 2.4, + "S06": 2.4, + "S42": 2.3, + "E87": 2.3, + "M25": 2.3, + "E86": 2.3, + "R54": 2.2, + "Z50": 2.1, + "F03": 2.1, + "W18": 2.1, + "Z75": 2.0, + "F01": 2.0, + "S80": 2.0, + "L03": 2.0, + "H54": 1.9, + "E53": 1.9, + "Z60": 1.8, + "G20": 1.8, + "R55": 1.8, + "S22": 1.8, + "K59": 1.8, + "N17": 1.8, + "L89": 1.7, + "Z22": 1.7, + "B95": 1.7, + "L97": 1.6, + "R44": 1.6, + "K26": 1.6, + "I95": 1.6, + "N19": 1.6, + "A41": 1.6, + "Z87": 1.5, + "J96": 1.5, + "X59": 1.5, + "M19": 1.5, + "G40": 1.5, + "M81": 1.4, + "S72": 1.4, + "S32": 1.4, + "E16": 1.4, + "R94": 1.4, + "N18": 1.4, + "R33": 1.3, + "R69": 1.3, + "N28": 1.3, + "R32": 1.2, + "G31": 1.2, + "Y95": 1.2, + "S09": 1.2, + "R45": 1.2, + "G45": 1.2, + "Z74": 1.1, + "M79": 1.1, + "W06": 1.1, + "S01": 1.1, + "A04": 1.1, + "A09": 1.1, + "J18": 1.1, + "J69": 1.0, + "R47": 1.0, + "E55": 1.0, + "Z93": 1.0, + "R02": 1.0, + "R63": 0.9, + "H91": 0.9, + "W10": 0.9, + "W01": 0.9, + "E05": 0.9, + "M41": 0.9, + "R13": 0.8, + "Z99": 0.8, + "U80": 0.8, + "M80": 0.8, + "K92": 0.8, + "I63": 0.8, + "N20": 0.7, + "F10": 0.7, + "Y84": 0.7, + "R00": 0.7, + "J22": 0.7, + "Z73": 0.6, + "R79": 0.6, + "Z91": 0.5, + "S51": 0.5, + "F32": 0.5, + "M48": 0.5, + "E83": 0.4, + "M15": 0.4, + "D64": 0.4, + "L08": 0.4, + "R11": 0.3, + "K52": 0.3, + "R50": 0.1, +} + + +def _read_labels(path: Path) -> list[dict[str, str | int]]: + rows: list[dict[str, str | int]] = [] + with path.open(encoding="utf-8") as f: + for i, line in enumerate(f): + line = line.strip() + if not line: + continue + parts = line.split(maxsplit=1) + code = parts[0].strip().upper() + name = parts[1].strip() if len(parts) > 1 else "" + rows.append({"token_id": i + 3, "label_code": code, "label_name": name}) + return rows + + +def main() -> None: + labels = _read_labels(LABELS) + label_codes = {str(row["label_code"]) for row in labels} + missing = sorted(set(UK_HFRS_WEIGHTS) - label_codes) + + rows = [] + for row in labels: + code = str(row["label_code"]) + weight = float(UK_HFRS_WEIGHTS.get(code, 0.0)) + rows.append( + { + **row, + "hfrs_dimension_id": "hfrs_weighted_disease_expression", + "hfrs_dimension": "DeepHealth HFRS-weighted disease expression", + "hfrs_key_area": "UK-HFRS", + "hfrs_weight": weight, + "hfrs_source": ( + "Gilbert et al. Lancet 2018 supplementary appendix Table A2" + ), + "match_source": "exact_three_character_icd10" if weight else "not_in_hfrs", + } + ) + + fieldnames = [ + "token_id", + "label_code", + "label_name", + "hfrs_dimension_id", + "hfrs_dimension", + "hfrs_key_area", + "hfrs_weight", + "hfrs_source", + "match_source", + ] + with OUT.open("w", newline="", encoding="utf-8-sig") as f: + writer = csv.DictWriter(f, fieldnames=fieldnames) + writer.writeheader() + writer.writerows(rows) + + with MISSING_OUT.open("w", newline="", encoding="utf-8-sig") as f: + writer = csv.DictWriter( + f, + fieldnames=[ + "hfrs_source_code", + "hfrs_weight", + "missing_reason", + "hfrs_source", + ], + ) + writer.writeheader() + for code in missing: + writer.writerow( + { + "hfrs_source_code": code, + "hfrs_weight": UK_HFRS_WEIGHTS[code], + "missing_reason": "not_present_in_labels_csv", + "hfrs_source": ( + "Gilbert et al. Lancet 2018 supplementary appendix Table A2" + ), + } + ) + + nonzero = sum(1 for row in rows if float(row["hfrs_weight"]) != 0.0) + print(f"labels: {len(rows)}") + print(f"uk_hfrs_codes: {len(UK_HFRS_WEIGHTS)}") + print(f"matched_nonzero_labels: {nonzero}") + print(f"missing_hfrs_codes: {len(missing)}") + print(f"output: {OUT}") + print(f"missing_output: {MISSING_OUT}") + + +if __name__ == "__main__": + main() diff --git a/burden_index.py b/burden_index.py index 398569f..a042009 100644 --- a/burden_index.py +++ b/burden_index.py @@ -2,12 +2,13 @@ from __future__ import annotations from dataclasses import dataclass from pathlib import Path -from typing import Any, Literal, Sequence +from typing import Any, Sequence import numpy as np import torch import torch.nn.functional as F +from eval_data import load_sequence_eval_dataset from evaluate_auc_v2 import ( build_model_from_dataset, load_checkpoint_state_dict, @@ -16,15 +17,11 @@ from evaluate_auc_v2 import ( resolve_dist_mode_for_checkpoint, validate_dataset_metadata, ) -from eval_data import load_sequence_eval_dataset from targets import CHECKUP_IDX, NO_EVENT_IDX, PAD_IDX -FormedBurdenMode = Literal["observed", "model_weighted"] - - @dataclass(frozen=True) -class BurdenContext: +class DeepHealthContext: model: torch.nn.Module dataset: Any cfg: dict[str, Any] @@ -34,33 +31,35 @@ class BurdenContext: @dataclass(frozen=True) -class DiseaseBurdenResult: - disease_id: int - formed: float - future: float - total: float - formed_mode: str - horizon: float +class DiseaseExpressionResult: + disease_ids: np.ndarray + expression: np.ndarray + t_query: float @dataclass(frozen=True) -class BurdenIndexResult: - historical: np.ndarray - future: np.ndarray - total: np.ndarray +class OrganInvolvementResult: + organ_ids: list[str] + involvement: np.ndarray disease_ids: np.ndarray - formed: np.ndarray - disease_future: np.ndarray - disease_total: np.ndarray - formed_mode: str - horizon: float + expression: np.ndarray + t_query: float -def load_burden_context( +@dataclass(frozen=True) +class FrailtyRiskResult: + frailty_risk_index: float + disease_ids: np.ndarray + expression: np.ndarray + weights: np.ndarray + t_query: float + + +def load_deephealth_context( run_path: str | Path, *, device: str | torch.device | None = None, -) -> BurdenContext: +) -> DeepHealthContext: run_path = Path(run_path) config_path = run_path / "train_config.json" model_ckpt_path = run_path / "best_model.pt" @@ -73,13 +72,13 @@ def load_burden_context( model_target_mode = str(cfg.get("model_target_mode", "next_token")).lower() if model_target_mode == "next_token": raise RuntimeError( - "Burden Index computation requires an all_future checkpoint because " - "it uses p_d(h, Delta). The provided run is model_target_mode='next_token'." + "Disease expression indices require an all_future checkpoint because " + "they use p_d(h, Delta). The provided run is model_target_mode='next_token'." ) if model_target_mode != "all_future": raise ValueError( - "train_config.json model_target_mode must be all_future for burden " - f"computation, got {model_target_mode!r}." + "train_config.json model_target_mode must be all_future, got " + f"{model_target_mode!r}." ) device_obj = torch.device( @@ -88,20 +87,17 @@ def load_burden_context( if device_obj.type == "cuda" and not torch.cuda.is_available(): raise RuntimeError(f"Requested device {device_obj}, but CUDA is not available.") - data_prefix = cfg.get("data_prefix", "ukb") - labels_file = cfg.get("labels_file", "labels.csv") - extra_info_types = cfg.get("extra_info_types", None) dataset = load_sequence_eval_dataset( model_target_mode="all_future", - data_prefix=data_prefix, - labels_file=labels_file, + data_prefix=cfg.get("data_prefix", "ukb"), + labels_file=cfg.get("labels_file", "labels.csv"), no_event_interval_years=float(cfg.get("no_event_interval_years", 5.0)), include_no_event_in_uts_target=bool( cfg.get("include_no_event_in_uts_target", False) ), min_history_events=int(cfg.get("all_future_min_history_events", 1)), min_future_events=int(cfg.get("all_future_min_future_events", 1)), - extra_info_types=extra_info_types, + extra_info_types=cfg.get("extra_info_types", None), ) validate_dataset_metadata(dataset, cfg) @@ -115,12 +111,11 @@ def load_burden_context( cfg_model = dict(cfg) cfg_model["dist_mode"] = dist_mode - args = _ConfigNamespace() - model = build_model_from_dataset(args, cfg_model, dataset) + model = build_model_from_dataset(_ConfigNamespace(), cfg_model, dataset) load_model_state(model, state_dict) model.eval().to(device_obj) - return BurdenContext( + return DeepHealthContext( model=model, dataset=dataset, cfg=cfg, @@ -131,56 +126,9 @@ def load_burden_context( @torch.inference_mode() -def compute_disease_burden( +def compute_disease_expression( *, run_path: str | Path, - disease_id: int, - event_seq: Sequence[int] | np.ndarray, - time_seq: Sequence[float] | np.ndarray, - sex: int, - other_type: Sequence[int] | np.ndarray, - other_value: Sequence[float] | np.ndarray, - other_value_kind: Sequence[int] | np.ndarray, - other_time: Sequence[float] | np.ndarray, - t_query: float, - horizon: float, - formed_mode: FormedBurdenMode, - device: str | torch.device | None = None, - context: BurdenContext | None = None, -) -> DiseaseBurdenResult: - ctx = context or load_burden_context(run_path, device=device) - disease_ids = np.asarray([int(disease_id)], dtype=np.int64) - formed, future_prob = _compute_disease_components( - ctx=ctx, - disease_ids=disease_ids, - event_seq=event_seq, - time_seq=time_seq, - sex=sex, - other_type=other_type, - other_value=other_value, - other_value_kind=other_value_kind, - other_time=other_time, - t_query=float(t_query), - horizon=float(horizon), - formed_mode=formed_mode, - ) - future = (1.0 - formed) * future_prob - total = formed + future - return DiseaseBurdenResult( - disease_id=int(disease_id), - formed=float(formed[0]), - future=float(future[0]), - total=float(total[0]), - formed_mode=str(formed_mode), - horizon=float(horizon), - ) - - -@torch.inference_mode() -def compute_burden_index( - *, - run_path: str | Path, - burden_matrix: np.ndarray, disease_ids: Sequence[int] | np.ndarray, event_seq: Sequence[int] | np.ndarray, time_seq: Sequence[float] | np.ndarray, @@ -190,26 +138,12 @@ def compute_burden_index( other_value_kind: Sequence[int] | np.ndarray, other_time: Sequence[float] | np.ndarray, t_query: float, - horizon: float, - formed_mode: FormedBurdenMode, device: str | torch.device | None = None, - context: BurdenContext | None = None, -) -> BurdenIndexResult: - ctx = context or load_burden_context(run_path, device=device) + context: DeepHealthContext | None = None, +) -> DiseaseExpressionResult: + ctx = context or load_deephealth_context(run_path, device=device) disease_ids_arr = np.asarray(disease_ids, dtype=np.int64) - if disease_ids_arr.ndim != 1 or disease_ids_arr.size == 0: - raise ValueError("disease_ids must be a non-empty 1D sequence.") - - A = np.asarray(burden_matrix, dtype=np.float64) - if A.ndim != 2: - raise ValueError(f"burden_matrix must be 2D, got shape {A.shape}") - if A.shape[1] != disease_ids_arr.size: - raise ValueError( - "burden_matrix columns must match disease_ids length, got " - f"{A.shape[1]} columns vs {disease_ids_arr.size} disease ids." - ) - - formed, future_prob = _compute_disease_components( + expression = model_implied_disease_expression( ctx=ctx, disease_ids=disease_ids_arr, event_seq=event_seq, @@ -220,36 +154,48 @@ def compute_burden_index( other_value_kind=other_value_kind, other_time=other_time, t_query=float(t_query), - horizon=float(horizon), - formed_mode=formed_mode, ) - disease_future = (1.0 - formed) * future_prob - disease_total = formed + disease_future - - historical = A @ formed - future = A @ disease_future - total = A @ disease_total - return BurdenIndexResult( - historical=historical, - future=future, - total=total, + return DiseaseExpressionResult( disease_ids=disease_ids_arr.copy(), - formed=formed, - disease_future=disease_future, - disease_total=disease_total, - formed_mode=str(formed_mode), - horizon=float(horizon), + expression=expression, + t_query=float(t_query), ) -class _ConfigNamespace: - def __getattr__(self, _name: str) -> None: - return None - - -def _compute_disease_components( +def compute_organ_involvement_from_expression( *, - ctx: BurdenContext, + expression: Sequence[float] | np.ndarray, + organ_matrix: np.ndarray, +) -> np.ndarray: + z = np.asarray(expression, dtype=np.float64) + A = np.asarray(organ_matrix, dtype=np.float64) + if A.ndim != 2: + raise ValueError(f"organ_matrix must be 2D, got shape {A.shape}") + if z.ndim != 1 or A.shape[1] != z.size: + raise ValueError( + "expression must be 1D and match organ_matrix columns, got " + f"{z.shape} and {A.shape}" + ) + intensity = -np.log1p(-np.clip(z, 0.0, 1.0 - 1e-7)) + return -np.expm1(-(A @ intensity)) + + +def compute_frailty_risk_from_expression( + *, + expression: Sequence[float] | np.ndarray, + hfrs_weights: Sequence[float] | np.ndarray, +) -> float: + z = np.asarray(expression, dtype=np.float64) + w = np.asarray(hfrs_weights, dtype=np.float64) + if z.shape != w.shape: + raise ValueError(f"expression and hfrs_weights shape mismatch: {z.shape} vs {w.shape}") + return float(np.dot(w, z)) + + +@torch.inference_mode() +def model_implied_disease_expression( + *, + ctx: DeepHealthContext, disease_ids: np.ndarray, event_seq: Sequence[int] | np.ndarray, time_seq: Sequence[float] | np.ndarray, @@ -259,41 +205,30 @@ def _compute_disease_components( other_value_kind: Sequence[int] | np.ndarray, other_time: Sequence[float] | np.ndarray, t_query: float, - horizon: float, - formed_mode: FormedBurdenMode, -) -> tuple[np.ndarray, np.ndarray]: - formed_mode = _validate_formed_mode(formed_mode) +) -> np.ndarray: disease_ids = np.asarray(disease_ids, dtype=np.int64) _validate_disease_ids(ctx, disease_ids) event_seq_arr, time_seq_arr = _validate_event_inputs(event_seq, time_seq) other_type_arr, other_value_arr, other_value_kind_arr, other_time_arr = ( _validate_other_inputs(other_type, other_value, other_value_kind, other_time) ) - if horizon < 0: - raise ValueError(f"horizon must be non-negative, got {horizon}") + grid = build_readout_grid( + event_seq=event_seq_arr, + time_seq=time_seq_arr, + other_type=other_type_arr, + other_time=other_time_arr, + t_query=float(t_query), + ) + if grid.size == 0: + return np.zeros(disease_ids.size, dtype=np.float64) - if formed_mode == "observed": - formed = _observed_formed_burden( - disease_ids=disease_ids, - event_seq=event_seq_arr, - time_seq=time_seq_arr, - t_query=t_query, - ) - else: - formed = _model_weighted_formed_burden( - ctx=ctx, - disease_ids=disease_ids, - event_seq=event_seq_arr, - time_seq=time_seq_arr, - sex=sex, - other_type=other_type_arr, - other_value=other_value_arr, - other_value_kind=other_value_kind_arr, - other_time=other_time_arr, - t_query=t_query, - ) + end_times = np.concatenate([grid[1:], np.asarray([t_query], dtype=np.float32)]) + deltas = np.maximum(end_times - grid, 0.0).astype(np.float32) + valid = deltas > 0 + if not np.any(valid): + return np.zeros(disease_ids.size, dtype=np.float64) - hidden_query = _query_hidden( + hidden = query_hidden( ctx=ctx, event_seq=event_seq_arr, time_seq=time_seq_arr, @@ -302,84 +237,19 @@ def _compute_disease_components( other_value=other_value_arr, other_value_kind=other_value_kind_arr, other_time=other_time_arr, - query_times=np.asarray([t_query], dtype=np.float32), + query_times=grid[valid].astype(np.float32), ) - future_prob = _probabilities_from_hidden( - ctx=ctx, - hidden=hidden_query, - disease_ids=disease_ids, - deltas=np.asarray([horizon], dtype=np.float32), - )[0] - return formed.astype(np.float64), future_prob.astype(np.float64) - - -def _model_weighted_formed_burden( - *, - ctx: BurdenContext, - disease_ids: np.ndarray, - event_seq: np.ndarray, - time_seq: np.ndarray, - sex: int, - other_type: np.ndarray, - other_value: np.ndarray, - other_value_kind: np.ndarray, - other_time: np.ndarray, - t_query: float, -) -> np.ndarray: - grid = _build_readout_grid( - event_seq=event_seq, - time_seq=time_seq, - other_type=other_type, - other_time=other_time, - t_query=t_query, - ) - if grid.size == 0: - return np.zeros(disease_ids.size, dtype=np.float64) - - end_times = np.concatenate([grid[1:], np.asarray([t_query], dtype=np.float32)]) - deltas = np.maximum(end_times - grid, 0.0).astype(np.float32) - if np.all(deltas <= 0): - return np.zeros(disease_ids.size, dtype=np.float64) - - hidden = _query_hidden( - ctx=ctx, - event_seq=event_seq, - time_seq=time_seq, - sex=sex, - other_type=other_type, - other_value=other_value, - other_value_kind=other_value_kind, - other_time=other_time, - query_times=grid.astype(np.float32), - ) - interval_prob = _probabilities_from_hidden( + interval_prob = probabilities_from_hidden( ctx=ctx, hidden=hidden, disease_ids=disease_ids, - deltas=deltas, - ).astype(np.float64) - survival = np.prod(1.0 - np.clip(interval_prob, 0.0, 1.0), axis=0) - return 1.0 - survival - - -def _observed_formed_burden( - *, - disease_ids: np.ndarray, - event_seq: np.ndarray, - time_seq: np.ndarray, - t_query: float, -) -> np.ndarray: - valid = ( - (time_seq <= np.float32(t_query)) - & (event_seq > PAD_IDX) - & (event_seq != CHECKUP_IDX) - & (event_seq != NO_EVENT_IDX) + deltas=deltas[valid], ) - observed = set(int(x) for x in event_seq[valid].tolist()) - return np.asarray([1.0 if int(d) in observed else 0.0 for d in disease_ids]) + survival = np.prod(1.0 - np.clip(interval_prob, 0.0, 1.0), axis=0) + return (1.0 - survival).astype(np.float64, copy=False) -def _build_readout_grid( +def build_readout_grid( *, event_seq: np.ndarray, time_seq: np.ndarray, @@ -400,9 +270,10 @@ def _build_readout_grid( return np.unique(times) -def _query_hidden( +@torch.inference_mode() +def query_hidden( *, - ctx: BurdenContext, + ctx: DeepHealthContext, event_seq: np.ndarray, time_seq: np.ndarray, sex: int, @@ -430,31 +301,24 @@ def _query_hidden( tq = torch.from_numpy(query_times.astype(np.float32, copy=False)).float() event = event.to(ctx.device) - times = times.to(ctx.device) - other_t = other_t.to(ctx.device) - other_v = other_v.to(ctx.device) - other_k = other_k.to(ctx.device) - other_tm = other_tm.to(ctx.device) - sex_t = sex_t.to(ctx.device) - tq = tq.to(ctx.device) - return ctx.model( event_seq=event, - time_seq=times, - sex=sex_t, + time_seq=times.to(ctx.device), + sex=sex_t.to(ctx.device), padding_mask=event > PAD_IDX, - t_query=tq, - other_type=other_t, - other_value=other_v, - other_value_kind=other_k, - other_time=other_tm, + t_query=tq.to(ctx.device), + other_type=other_t.to(ctx.device), + other_value=other_v.to(ctx.device), + other_value_kind=other_k.to(ctx.device), + other_time=other_tm.to(ctx.device), target_mode="all_future", ) -def _probabilities_from_hidden( +@torch.inference_mode() +def probabilities_from_hidden( *, - ctx: BurdenContext, + ctx: DeepHealthContext, hidden: torch.Tensor, disease_ids: np.ndarray, deltas: np.ndarray, @@ -489,16 +353,12 @@ def _probabilities_from_hidden( return prob.detach().cpu().numpy().astype(np.float64, copy=False) -def _validate_formed_mode(mode: str) -> FormedBurdenMode: - if mode not in {"observed", "model_weighted"}: - raise ValueError( - "formed_mode must be either 'observed' or 'model_weighted', " - f"got {mode!r}." - ) - return mode # type: ignore[return-value] +class _ConfigNamespace: + def __getattr__(self, _name: str) -> None: + return None -def _validate_disease_ids(ctx: BurdenContext, disease_ids: np.ndarray) -> None: +def _validate_disease_ids(ctx: DeepHealthContext, disease_ids: np.ndarray) -> None: if disease_ids.ndim != 1 or disease_ids.size == 0: raise ValueError("disease_ids must be a non-empty 1D array.") vocab_size = int(getattr(ctx.model, "vocab_size", ctx.model.risk_head.out_features)) diff --git a/burden_index_method.tex b/burden_index_method.tex index 4565b42..6470276 100644 --- a/burden_index_method.tex +++ b/burden_index_method.tex @@ -1,13 +1,12 @@ \documentclass[11pt]{article} \usepackage[margin=1in]{geometry} -\usepackage{amsmath, amssymb, amsfonts} -\usepackage{bm} +\usepackage{amsmath, amssymb} \usepackage{booktabs} \usepackage{enumitem} \usepackage{hyperref} -\title{DeepHealth Burden Indices: Dynamic Organ and Functional Burden} +\title{DeepHealth Disease Expression, Organ Involvement, and Frailty Risk Indices} \author{} \date{} @@ -16,561 +15,147 @@ \maketitle \begin{abstract} -DeepHealth produces a query-time hidden representation \(h(t)\) and -disease-specific future risk functions \(p_d(h,\Delta)\). These disease-level -outputs are clinically granular but difficult to interpret directly as a -patient-level health state. We therefore define Burden Indices (BI) that -aggregate historical and predicted disease burden into higher-level, -interpretable dimensions. The Organ Burden Index (OBI) maps diseases to -anatomical systems, while the Functional Burden Index (FBI) maps diseases to -function- and frailty-related burden domains, anchored by CIHI-HFRM-style -diagnosis weights when available. For formed burden, we distinguish an -observed-anchored version based on actual historical diagnoses and a -model-weighted version based on DeepHealth's historical risk trajectory. The -indices are burden measures, not direct health reserve measures, because the -current model is supervised by disease events rather than direct functional -outcomes such as ADL/IADL, gait speed, grip strength, cognition, or recovery -capacity. +DeepHealth provides a query-time hidden state \(h(t)\) and disease-specific +risk functions \(p_d(h,\Delta)\). We use these outputs to define a continuous +disease expression rate \(z_d(t)\). This quantity should be interpreted as how +much disease \(d\) is model-implied to have formed or expressed by query time +\(t\), not as true physiological damage. Based on \(z_d(t)\), we define two +downstream indices: an organ involvement index, which summarizes whether an +organ-age-inspired clinical system is involved by any related disease process, +and a DeepHealth-HFRS frailty risk index, which is the original UK-HFRS weighted +sum with binary disease occurrence replaced by continuous disease expression. \end{abstract} -\section{Motivation} +\section{Disease Expression Rate} -At query time \(t\), DeepHealth produces a hidden state \(h(t)\) and -disease-level risk predictions +For a patient queried at time \(t\), let the historical readout times be \[ - p_d(h(t), \tau), \qquad d = 1,\ldots,D, + t_0 < t_1 < \cdots < t_n \le t,\qquad t_{n+1}=t. \] -where \(p_d(h(t),\tau)\) is the predicted probability of disease \(d\) occurring -within future horizon \(\tau\). These outputs are useful for disease-specific -risk prediction, but they do not directly answer patient-level questions such as -where disease burden is concentrated or how much functional vulnerability is -implied by the disease profile. - -We introduce Burden Indices to summarize disease-level predictions into -interpretable state representations: +For each interval \([t_i,t_{i+1}]\), DeepHealth produces a hidden state +\(h_i=h(t_i)\) and an interval risk \[ - \text{disease-level risk} - \quad \longrightarrow \quad - \text{system-level burden}. + q_{d,i}(t)=p_d(h_i,t_{i+1}-t_i). \] -The indices combine two components: -\begin{enumerate}[leftmargin=*] - \item formed burden: disease burden already accumulated by query time \(t\); - \item future expected burden: disease burden expected to newly form within - horizon \(\tau\). -\end{enumerate} - -At the current stage, these quantities should be called burden indices rather -than health reserve or health state scores. The current model is trained and -validated primarily on ICD disease events. Its directly verifiable semantics are -disease occurrence and disease risk. Without direct functional labels or a -calibrated healthy reference state, quantities such as \(100-\text{burden}\) -cannot be rigorously interpreted as remaining health reserve. - -\section{Two Burden Spaces} - -We define two complementary burden spaces. - -\subsection{Organ Burden Index} - -The Organ Burden Index (OBI) maps disease burden to anatomical systems. It -answers: +The model-implied disease expression rate is defined by noisy-or accumulation: \[ - \text{Which organs or anatomical systems carry the largest pathological burden?} -\] -Typical dimensions may include heart/vascular, brain/neurological, kidney, -lung, liver/digestive, metabolic/endocrine, musculoskeletal, hematologic, and -malignancy-related systems. The mapping matrix is denoted -\[ - A^{\mathrm{organ}} \in \mathbb{R}_{\ge 0}^{K_o \times D}, -\] -where \(A^{\mathrm{organ}}_{k,d}\) is the contribution weight from disease -\(d\) to organ dimension \(k\). - -\subsection{Functional Burden Index} - -The Functional Burden Index (FBI) maps disease burden to function- and -frailty-related diagnostic burden domains. It answers: -\[ - \text{How much functional vulnerability is implied by the disease burden?} -\] -Candidate dimensions include mobility burden, cognition burden, mood burden, -sensory burden, nutrition burden, infection or immune vulnerability burden, -functional dependence burden, and comorbidity burden. - -When CIHI-HFRM or another validated hospital frailty risk measure code list is -available, it should be used as the primary anchor for FBI. The mapping matrix -is denoted -\[ - A^{\mathrm{func}} \in \mathbb{R}_{\ge 0}^{K_f \times D}, -\] -where \(A^{\mathrm{func}}_{k,d}\) is the contribution weight from disease \(d\) -to functional burden dimension \(k\). - -OBI and FBI are not redundant. OBI describes where pathology is concentrated, -whereas FBI describes how disease burden may translate into functional -vulnerability. For example, stroke contributes primarily to brain/vascular -burden in OBI, but may contribute to mobility, cognition, sensory, and -functional dependence burden in FBI. - -\section{Model Outputs and Disease Risk Function} - -For each hidden state \(h\), DeepHealth defines a disease-specific future risk -function -\[ - p_d(h,\Delta), -\] -where \(\Delta \ge 0\) is the time horizon. The risk function is produced by the -all-future model. Let -\[ - \eta_d(h) = \operatorname{risk\_head}(h)_d, - \qquad - \lambda_d(h) = \operatorname{softplus}(\eta_d(h)). -\] - -For the exponential all-future model, -\[ - p_d(h,\Delta) - = - 1-\exp[-\lambda_d(h)\Delta]. -\] - -For the Weibull all-future model, with -\[ - \rho_d(h)=\operatorname{softplus}(\operatorname{rho\_head}(h)_d), -\] -the risk function is -\[ - p_d(h,\Delta) - = - 1-\exp[-\lambda_d(h)\Delta^{\rho_d(h)}]. -\] - -The burden formulation below only assumes access to \(p_d(h,\Delta)\); the -exponential and Weibull cases are specializations. - -\section{Formed Burden} - -For a patient queried at time \(t\), let the available historical readout times -be -\[ - t_0 < t_1 < \cdots < t_n \le t. -\] -For notational convenience, define -\[ - t_{n+1}=t. -\] -The historical trajectory is partitioned into adjacent, non-overlapping -intervals -\[ - [t_i,t_{i+1}], \qquad i=0,\ldots,n. -\] -Let -\[ - h_i = h(t_i), \qquad \Delta_i = t_{i+1}-t_i. -\] - -The interval-level model-implied probability for disease \(d\) is -\[ - q_{d,i}(t) = p_d(h_i,\Delta_i). -\] - -\subsection{Model-Weighted Formed Burden} - -The model-weighted formed burden uses DeepHealth's own historical risk -trajectory to quantify how strongly disease \(d\) is represented as formed -burden by time \(t\). It is defined by noisy-or accumulation over historical -intervals: -\[ - z^{\mathrm{model}}_d(t) + z_d(t) = 1-\prod_{i=0}^{n}\left[1-q_{d,i}(t)\right]. \] -Equivalently, +Informally, \(z_d(t)\) is the degree to which disease \(d\) is expressed in the +patient by time \(t\). Unlike a raw diagnosis indicator, it is continuous and +can reflect heterogeneity within the same ICD label. + +\section{Organ Involvement Index} + +The organ index is not a frailty score, health reserve score, or organ age. It +is an organ involvement index. Let \(\mathcal{D}_k\) be the set of diseases +assigned to organ/system \(k\). Define disease expression intensity as \[ - z^{\mathrm{model}}_d(t) + \Lambda_d(t)=-\log\left[1-z_d(t)\right]. +\] +The equal-weight organ involvement index is +\[ + O_k(t) = - 1-\prod_{i=0}^{n} - \left[ - 1-p_d\!\left(h(t_i),t_{i+1}-t_i\right) - \right], - \qquad t_{n+1}=t. -\] - -This definition uses each segment of the historical trajectory exactly once and -therefore avoids repeatedly counting overlapping predictions from multiple -historical states to the same query time. - -\subsection{Observed-Anchored Formed Burden} - -The observed-anchored formed burden treats historical diagnoses as factual -evidence. Define the observed historical disease indicator -\[ - o_d(t) - = - \mathbb{I}\left\{ - \exists j:\; \mathrm{event}_j=d,\; \mathrm{time}_j\le t - \right\}. -\] -The observed-anchored version is -\[ - z^{\mathrm{obs}}_d(t)=o_d(t). -\] - -This version is closest to diagnosis-code burden measures such as HFRM: once a -disease code has appeared before query time \(t\), the corresponding disease -burden component is considered present. It is maximally auditable and aligned -with code-based burden definitions, but it does not distinguish severity, -recency, or residual impact among patients with the same historical diagnosis. - -\subsection{Choice of Formed Burden} - -The two definitions represent different semantics: -\[ - z^{\mathrm{obs}}_d(t) - = - \text{observed diagnostic burden}, -\] -\[ - z^{\mathrm{model}}_d(t) - = - \text{model-weighted state burden}. -\] -The observed-anchored version should be used when the goal is to reproduce or -extend diagnosis-code burden measures. The model-weighted version should be used -when the goal is to let DeepHealth assign a continuous burden strength based on -the historical hidden-state trajectory. In the formulas below, \(z_d(t)\) -denotes either \(z^{\mathrm{obs}}_d(t)\) or \(z^{\mathrm{model}}_d(t)\), depending -on the selected BI variant. - -\subsection{Observed-Anchored versus Model-Weighted Burden} - -The observed-anchored and model-weighted definitions share the same purpose: -both quantify disease burden already formed by query time \(t\), before adding -future expected burden. They also use the same downstream BI equations; the only -difference is the definition of \(z_d(t)\). - -Their key difference is the evidence treated as primary. The observed-anchored -version treats diagnosis occurrence as the primary unit of evidence: -\[ - z^{\mathrm{obs}}_d(t)=1 - \quad\text{once disease } d \text{ has been observed before } t. -\] -This is appropriate when the burden index is intended to remain close to -diagnosis-code measures such as HFRM. It is transparent and robust to model -miscalibration, but it treats all historical occurrences of the same disease as -equally formed burden. - -The model-weighted version treats the DeepHealth risk trajectory as the primary -unit of evidence: -\[ - z^{\mathrm{model}}_d(t) - = - 1-\prod_i - \left[ - 1-p_d\!\left(h(t_i),t_{i+1}-t_i\right) - \right]. -\] -This version can assign different burden strengths to the same observed disease -depending on timing, surrounding history, extra-info context, and the hidden -state trajectory. It may better reflect state-dependent burden intensity, but it -can also downweight a disease that was truly observed if the model assigns low -historical probability. - -Thus the two variants answer related but non-identical questions: -\[ - z^{\mathrm{obs}}_d(t): - \text{Has disease } d \text{ been recorded as part of the patient's history?} -\] -\[ - z^{\mathrm{model}}_d(t): - \text{How strongly does the model-implied trajectory support burden from } - d \text{ by time } t? -\] -For this reason, both should be considered useful sensitivity variants. The -observed-anchored version is preferable for auditability and alignment with -existing code-based indices. The model-weighted version is preferable when the -goal is to use DeepHealth as a continuous state model and allow the learned -trajectory to modulate burden strength. - -\subsection{Cumulative Intensity Form} - -Define the interval cumulative intensity -\[ - \ell_d(h_i,\Delta_i) - = - -\log\left[1-p_d(h_i,\Delta_i)\right], -\] -and the accumulated historical intensity -\[ - \Lambda^{\mathrm{model}}_d(t)=\sum_{i=0}^{n}\ell_d(h_i,\Delta_i). -\] -Then -\[ - z^{\mathrm{model}}_d(t)=1-\exp[-\Lambda^{\mathrm{model}}_d(t)]. -\] - -For the exponential model, -\[ - \ell_d(h_i,\Delta_i)=\lambda_d(h_i)\Delta_i, -\] -so -\[ - z^{\mathrm{model}}_d(t) - = - 1-\exp\left[ - -\sum_{i=0}^{n} - \lambda_d\!\left(h(t_i)\right)(t_{i+1}-t_i) - \right]. -\] - -For the Weibull model, -\[ - \ell_d(h_i,\Delta_i) - = - \lambda_d(h_i)\Delta_i^{\rho_d(h_i)}, -\] -so -\[ - z^{\mathrm{model}}_d(t) - = - 1-\exp\left[ - -\sum_{i=0}^{n} - \lambda_d\!\left(h(t_i)\right) - (t_{i+1}-t_i)^{\rho_d(h(t_i))} - \right]. -\] - -\section{Future Expected Burden} - -The selected formed burden \(z_d(t)\) represents disease burden already formed -by query time \(t\). It can be either the observed-anchored burden -\(z^{\mathrm{obs}}_d(t)\) or the model-weighted burden -\(z^{\mathrm{model}}_d(t)\). The current future risk from query time \(t\) to -horizon \(\tau\) is -\[ - p_d(h(t),\tau). -\] -The future expected newly formed burden for disease \(d\) is defined as -\[ - f_d(t,\tau) - = - \left[1-z_d(t)\right]p_d(h(t),\tau). -\] -This term counts only the portion of disease burden that has not already formed -by time \(t\). The total dynamic disease burden contribution is -\[ - b_d(t,\tau) - = - z_d(t)+f_d(t,\tau). + 1-\exp\left( + -\sum_{d\in\mathcal{D}_k}\Lambda_d(t) + \right). \] Equivalently, \[ - b_d(t,\tau) + O_k(t) = 1- - \left[1-z_d(t)\right] - \left[1-p_d(h(t),\tau)\right]. + \prod_{d\in\mathcal{D}_k} + \left[1-z_d(t)\right]. \] -Thus \(b_d(t,\tau)\) can be interpreted as the probability that disease burden -for \(d\) has formed by time \(t\) or will newly form within the future horizon -\(\tau\). - -\section{Burden Index Definition} - -Let \(A \in \mathbb{R}_{\ge 0}^{K \times D}\) be a disease-to-burden mapping -matrix. The historical, future, and total burden indices for dimension \(k\) -are +Thus \(O_k(t)\in[0,1]\) is the probability-like degree to which organ/system +\(k\) is involved by at least one related disease process. In the current +version all diseases assigned to the same organ are equally weighted; this is a +first-stage structural definition. Future versions can introduce +organ-specific disease weights \(\alpha_{k,d}\): \[ - \operatorname{BI}^{\mathrm{hist}}_k(t) + O_k(t) = - \sum_{d=1}^{D} A_{k,d} z_d(t), -\] -\[ - \operatorname{BI}^{\mathrm{future}}_k(t,\tau) - = - \sum_{d=1}^{D} - A_{k,d} - \left[1-z_d(t)\right]p_d(h(t),\tau), -\] -and -\[ - \operatorname{BI}^{\mathrm{total}}_k(t,\tau) - = - \operatorname{BI}^{\mathrm{hist}}_k(t) - + - \operatorname{BI}^{\mathrm{future}}_k(t,\tau). -\] -Equivalently, -\[ - \operatorname{BI}^{\mathrm{total}}_k(t,\tau) - = - \sum_{d=1}^{D} - A_{k,d} - \left\{ - 1- - \left[1-z_d(t)\right] - \left[1-p_d(h(t),\tau)\right] - \right\}. + 1-\exp\left( + -\sum_{d\in\mathcal{D}_k}\alpha_{k,d}\Lambda_d(t) + \right). \] -For OBI, \(A=A^{\mathrm{organ}}\). For FBI, \(A=A^{\mathrm{func}}\). +\section{Organ List} -\section{Constructing the Mapping Matrices} - -\subsection{Organ Mapping Matrix} - -The organ mapping matrix should be constructed from code taxonomy or validated -clinical grouping systems rather than manually assigned arbitrary weights. In -the current ICD-token setting, the first version can use ICD chapters or -predefined ICD ranges to construct a sparse disease-to-organ mask -\[ - M^{\mathrm{organ}}_{k,d}\in\{0,1\}. -\] -Examples include: +The organ/system categories are inspired by organ-age studies, especially +organ-specific plasma proteomic aging models, and are adapted to ICD disease +labels. The current list is: \begin{center} \begin{tabular}{ll} \toprule -Dimension & Example ICD groups \\ +ID & Label \\ \midrule -Heart/vascular & I00--I99, optionally split into cardiac and vascular groups \\ -Brain/neurological & G00--G99, F00--F09, I60--I69 \\ -Kidney/urogenital & N00--N39, especially N17--N19 \\ -Lung/respiratory & J00--J99 \\ -Metabolic/endocrine & E00--E90 \\ -Liver/digestive & K00--K93, especially K70--K77 \\ -Musculoskeletal & M00--M99 \\ +brain\_neurologic & Brain and neurologic system \\ +heart & Heart \\ +artery\_vascular & Artery and vascular system \\ +immune & Immune and infection-related system \\ +intestine\_digestive & Intestine and digestive system \\ +kidney & Kidney and urinary system \\ +liver & Liver \\ +lung & Lung and respiratory system \\ +muscle\_musculoskeletal & Muscle and musculoskeletal system \\ +pancreas\_endocrine & Pancreas and endocrine system \\ +adipose\_metabolic & Adipose and metabolic system \\ +female\_reproductive & Female reproductive system \\ +male\_reproductive & Male reproductive system \\ +neoplasm & Neoplasm \\ \bottomrule \end{tabular} \end{center} +The neoplasm category is retained as a disease-system category rather than +forced into a single anatomical organ. Sex-specific reproductive diseases are +separated into female and male reproductive systems. -The simplest organ weights are +\section{DeepHealth-HFRS Frailty Risk Index} + +The original UK-HFRS is a weighted sum over binary disease occurrence: \[ - A^{\mathrm{organ}}_{k,d}=M^{\mathrm{organ}}_{k,d}. -\] -If longitudinal organ endpoint labels are available, the weights can be learned -under the mask: -\[ - A^{\mathrm{organ}}_{k,d}\ge 0, + \operatorname{HFRS}^{\mathrm{obs}}(t) + = + \sum_{d\in\mathcal{D}_{\mathrm{HFRS}}} + w^{\mathrm{HFRS}}_d\,o_d(t), \qquad - A^{\mathrm{organ}}_{k,d}=0 - \quad\text{if}\quad - M^{\mathrm{organ}}_{k,d}=0. + o_d(t)\in\{0,1\}. \] -This keeps the projection clinically interpretable while allowing data-driven -calibration. - -\subsection{Functional Mapping Matrix} - -The functional mapping matrix should be anchored by a validated frailty-related -diagnosis code set whenever possible. CIHI-HFRM or a closely related Hospital -Frailty Risk Measure provides a suitable starting point because it defines -frailty burden from diagnosis codes and associated weights. - -Let \(w^{\mathrm{HFRM}}_d\ge 0\) be the HFRM weight mapped to DeepHealth disease -token \(d\). If the HFRM code list is more granular than the DeepHealth ICD -token vocabulary, weights should be mapped by code prefix. For three-character -ICD tokens, a conservative default is +DeepHealth-HFRS keeps the published UK-HFRS weights and replaces the binary +disease state with the continuous DeepHealth disease expression rate: \[ - w^{\mathrm{HFRM}}_d + \operatorname{HFRS}^{\mathrm{DH}}(t) = - \max_{c:\, c \text{ maps to token } d} - w^{\mathrm{HFRM}}_c. -\] - -For total functional burden, the one-dimensional mapping is -\[ - A^{\mathrm{func,total}}_{1,d} - = - w^{\mathrm{HFRM}}_d. -\] -For domain-specific functional burden, define a grouping mask -\[ - G_{k,d}\in\{0,1\}, -\] -where \(G_{k,d}=1\) means HFRM-associated disease token \(d\) belongs to -functional burden domain \(k\). Then -\[ - A^{\mathrm{func}}_{k,d} - = - G_{k,d} w^{\mathrm{HFRM}}_d. -\] - -Candidate functional domains include mobility, cognition, mood, sensory, -nutrition, infection or immune vulnerability, functional dependence, and -comorbidity burden. These domain labels should be treated as diagnostic-burden -proxies unless direct functional measurements are available for calibration. - -\section{Normalization and Reporting} - -The raw burden index is an additive weighted burden: -\[ - \operatorname{BI}_k(t,\tau) - = - \sum_d A_{k,d} b_d(t,\tau). -\] -For interpretability, the system should report the decomposition -\[ - \operatorname{BI}^{\mathrm{hist}}_k(t), + \sum_{d\in\mathcal{D}_{\mathrm{HFRS}}} + w^{\mathrm{HFRS}}_d\,z_d(t), \qquad - \operatorname{BI}^{\mathrm{future}}_k(t,\tau), - \qquad - \operatorname{BI}^{\mathrm{total}}_k(t,\tau). + z_d(t)\in[0,1]. \] +This is a natural continuous extension of the original HFRS, so it can still be +called a frailty risk index. The semantic change is not the HFRS weight system; +the change is the disease state variable. -Optionally, a normalized burden can be reported as +\section{Current Implementation} + +The current code computes historical current-state indices only. No future +horizon is used. For each landmark age \(t\), it outputs: +\begin{itemize}[leftmargin=*] + \item \(z_d(t)\) internally as model-implied disease expression; + \item \(O_k(t)\) as equal-weight organ involvement; + \item \(\operatorname{HFRS}^{\mathrm{DH}}(t)\) as DeepHealth-HFRS frailty + risk. +\end{itemize} +The output table uses the columns \[ - \widetilde{\operatorname{BI}}_k(t,\tau) - = - \frac{ - \sum_d A_{k,d} b_d(t,\tau) - }{ - \sum_d A_{k,d} + \epsilon - }, + \texttt{index\_type},\quad + \texttt{index\_id},\quad + \texttt{index\_label},\quad + \texttt{index\_value}. \] -where \(\epsilon>0\) prevents division by zero. This normalized score lies on a -dimension-comparable scale when \(b_d(t,\tau)\in[0,1]\) and \(A_{k,d}\ge 0\). - -For cohort-level interpretation, an additional percentile score can be computed -within age- and sex-specific reference strata: -\[ - \operatorname{PercentileBI}_k(t,\tau) - = - \operatorname{rank}_{\mathrm{age,sex}} - \left( - \operatorname{BI}^{\mathrm{total}}_k(t,\tau) - \right). -\] -This percentile is a relative burden ranking, not a health reserve percentage. - -\section{Validation} - -OBI and FBI should be validated against different endpoints. - -For OBI, validation endpoints should be organ-system-specific future events, for -example cardiac events for heart/vascular burden, stroke or dementia for -brain/neurological burden, CKD progression for kidney burden, and respiratory -events for lung burden. - -For FBI, validation should use CIHI-HFRM-style frailty burden, frailty-related -diagnosis endpoints, hospitalization, mortality, care dependence proxies, or -direct functional outcomes if available. If direct functional labels such as -ADL/IADL, gait speed, grip strength, cognitive tests, or recovery measures are -not available, FBI should be reported as a diagnosis-risk-based functional -burden proxy rather than a direct functional reserve measure. - -\section{Summary} - -DeepHealth Burden Indices transform disease-level risk predictions into -interpretable burden representations. Formed burden can be defined either as -observed-anchored burden \(z^{\mathrm{obs}}_d(t)\), which follows factual -diagnosis history, or as model-weighted burden \(z^{\mathrm{model}}_d(t)\), -which accumulates DeepHealth's predicted interval risks along the hidden-state -trajectory. The future expected burden is the residual future risk among disease -burden not already formed. OBI uses anatomical disease groupings to summarize -where pathological burden is concentrated. FBI uses CIHI-HFRM-style -frailty-related diagnosis weights to summarize functional vulnerability burden. -Together, they provide two complementary views of disease burden while allowing -the formed-burden semantics to be chosen explicitly. \end{document} diff --git a/burden_index_method_zh.tex b/burden_index_method_zh.tex index 8af59f9..ff29975 100644 --- a/burden_index_method_zh.tex +++ b/burden_index_method_zh.tex @@ -1,13 +1,12 @@ \documentclass[11pt]{ctexart} \usepackage[margin=1in]{geometry} -\usepackage{amsmath, amssymb, amsfonts} -\usepackage{bm} +\usepackage{amsmath, amssymb} \usepackage{booktabs} \usepackage{enumitem} \usepackage{hyperref} -\title{DeepHealth 负担指数：动态器官负担与功能负担} +\title{DeepHealth 疾病表达率、器官受累指数与衰弱风险指数} \author{} \date{} @@ -16,476 +15,128 @@ \maketitle \begin{abstract} -DeepHealth 在查询时刻 \(t\) 输出隐含状态 \(h(t)\)，并基于该隐含状态给出疾病级未来风险函数 -\(p_d(h,\Delta)\)。疾病级输出足够细，但很难直接解释为个体层面的健康状态。因此，我们定义负担指数 -（Burden Indices, BI），将历史已经形成的疾病负担和未来预期新增疾病负担聚合为更高层、可解释的表征。 -器官负担指数（Organ Burden Index, OBI）将疾病映射到解剖系统；功能负担指数 -（Functional Burden Index, FBI）将疾病映射到功能受损和衰弱相关的诊断负担维度，并在条件允许时使用 -CIHI-HFRM 风格的诊断代码权重作为锚点。对于已形成负担，我们区分基于真实历史诊断的观测锚定版本， -以及基于 DeepHealth 历史风险轨迹的模型加权版本。当前阶段这些指标应被称为负担指数，而不是健康储备或健康状态评分， -因为当前模型主要由疾病事件监督，而不是由 ADL/IADL、步速、握力、认知测验或恢复能力等真实功能结局监督。 +DeepHealth 在查询时刻 \(t\) 输出隐含状态 \(h(t)\)，并给出疾病风险函数 +\(p_d(h,\Delta)\)。我们首先定义连续的疾病表达率 \(z_d(t)\)：它表示模型认为疾病 \(d\) +截至 \(t\) 在该个体身上形成或表达了多少，而不是疾病造成的真实损害。基于 \(z_d(t)\)， +本文定义两类指数：器官受累指数和 DeepHealth-HFRS 衰弱风险指数。前者表示器官/系统是否被相关疾病过程累及； +后者是原版 UK-HFRS 的自然连续化，即用连续疾病表达率替代二值疾病发生状态。 \end{abstract} -\section{动机} +\section{疾病表达率} -在查询时刻 \(t\)，DeepHealth 输出隐含状态 \(h(t)\)，并给出疾病级风险预测 +设历史 readout 时间为 \[ - p_d(h(t), \tau), \qquad d = 1,\ldots,D, + t_0 < t_1 < \cdots < t_n \le t,\qquad t_{n+1}=t. \] -其中 \(p_d(h(t),\tau)\) 表示疾病 \(d\) 在未来时间窗 \(\tau\) 内发生的预测概率。疾病级风险适合做单病种预测， -但不能直接回答个体层面的状态问题，例如疾病负担集中在哪些系统、当前已经形成了多少疾病负担、未来还可能新增多少负担， -以及疾病风险可能带来多少功能脆弱性。 - -因此，我们引入负担指数，将疾病级预测压缩为系统级负担表征： +在区间 \([t_i,t_{i+1}]\) 上，模型给出疾病 \(d\) 的区间风险 \[ - \text{疾病级风险} - \quad \longrightarrow \quad - \text{系统级负担}. + q_{d,i}(t)=p_d(h(t_i),t_{i+1}-t_i). \] -负担指数由两部分组成： -\begin{enumerate}[leftmargin=*] - \item 已形成负担：截至查询时刻 \(t\) 已经累积形成的疾病负担； - \item 未来预期负担：未来时间窗 \(\tau\) 内预期新增形成的疾病负担。 -\end{enumerate} - -当前阶段，这些量应称为负担指数，而不是健康储备或完整健康状态。原因是当前模型主要基于 ICD 疾病事件训练和验证， -其直接可验证语义是疾病发生和疾病风险，而不是真实功能表现或生理储备。没有直接功能标签或健康参考系校准时， -\(100-\text{负担}\) 不能被严谨解释为剩余健康储备。 - -\section{两类负担空间} - -我们定义两类互补的负担空间。 - -\subsection{器官负担指数} - -器官负担指数（OBI）将疾病负担映射到解剖系统，回答： +疾病表达率定义为 \[ - \text{病理负担主要集中在哪些器官或系统？} -\] -典型维度可以包括心脏/血管、脑/神经、肾脏、肺、肝脏/消化、代谢/内分泌、肌骨、血液以及肿瘤相关系统。 -其映射矩阵记为 -\[ - A^{\mathrm{organ}} \in \mathbb{R}_{\ge 0}^{K_o \times D}, -\] -其中 \(A^{\mathrm{organ}}_{k,d}\) 表示疾病 \(d\) 对器官维度 \(k\) 的贡献权重。 - -\subsection{功能负担指数} - -功能负担指数（FBI）将疾病负担映射到功能受损和衰弱相关的诊断负担维度，回答： -\[ - \text{这些疾病负担提示了多少功能脆弱性？} -\] -候选维度包括行动负担、认知负担、情绪负担、感官负担、营养负担、感染或免疫脆弱性负担、功能依赖负担和共病负担。 - -如果可以获得 CIHI-HFRM 或其他经过验证的住院衰弱风险诊断代码表，应优先将其作为 FBI 的锚点。 -其映射矩阵记为 -\[ - A^{\mathrm{func}} \in \mathbb{R}_{\ge 0}^{K_f \times D}, -\] -其中 \(A^{\mathrm{func}}_{k,d}\) 表示疾病 \(d\) 对功能负担维度 \(k\) 的贡献权重。 - -OBI 与 FBI 不是重复指标。OBI 描述病理负担的位置，FBI 描述疾病负担可能带来的功能脆弱性。例如，卒中在 OBI 中主要贡献脑/血管负担， -但在 FBI 中可能同时贡献行动、认知、感官和功能依赖负担。 - -\section{模型输出与疾病风险函数} - -对任意隐含状态 \(h\)，DeepHealth 定义疾病级未来风险函数 -\[ - p_d(h,\Delta), -\] -其中 \(\Delta \ge 0\) 是时间窗长度。该风险函数由 all-future 模型给出。记 -\[ - \eta_d(h) = \operatorname{risk\_head}(h)_d, - \qquad - \lambda_d(h) = \operatorname{softplus}(\eta_d(h)). -\] - -对于 exponential all-future 模型， -\[ - p_d(h,\Delta) - = - 1-\exp[-\lambda_d(h)\Delta]. -\] - -对于 Weibull all-future 模型，另有 -\[ - \rho_d(h)=\operatorname{softplus}(\operatorname{rho\_head}(h)_d), -\] -其风险函数为 -\[ - p_d(h,\Delta) - = - 1-\exp[-\lambda_d(h)\Delta^{\rho_d(h)}]. -\] - -下面的负担定义只要求能够访问 \(p_d(h,\Delta)\)。exponential 和 Weibull 是该定义的两个具体实现。 - -\section{已形成负担} - -对一个在时刻 \(t\) 查询的个体，设其历史 readout 时间点为 -\[ - t_0 < t_1 < \cdots < t_n \le t. -\] -为方便记号，定义 -\[ - t_{n+1}=t. -\] -于是历史轨迹被划分为相邻且不重叠的区间 -\[ - [t_i,t_{i+1}], \qquad i=0,\ldots,n. -\] -记 -\[ - h_i = h(t_i), \qquad \Delta_i = t_{i+1}-t_i. -\] - -疾病 \(d\) 在第 \(i\) 个历史区间内的模型推断概率为 -\[ - q_{d,i}(t) = p_d(h_i,\Delta_i). -\] - -\subsection{模型加权已形成负担} - -模型加权已形成负担使用 DeepHealth 自身的历史风险轨迹，刻画疾病 \(d\) 在查询时刻 \(t\) 之前已经形成的负担强度。 -它通过 noisy-or 沿历史区间累积定义： -\[ - z^{\mathrm{model}}_d(t) + z_d(t) = 1-\prod_{i=0}^{n}\left[1-q_{d,i}(t)\right]. \] -等价地， +直观上，\(z_d(t)\) 表示“这个病在该个体身上形成或表达了多少”。它不是二值诊断记录， +因此可以表达同一 ICD 标签下的个体异质性。 + +\section{器官受累指数} + +器官指数不定义为器官年龄、器官健康储备或器官衰弱，而定义为器官受累指数。设 \(\mathcal{D}_k\) +是归属于器官/系统 \(k\) 的疾病集合。定义疾病表达强度 \[ - z^{\mathrm{model}}_d(t) + \Lambda_d(t)=-\log\left[1-z_d(t)\right]. +\] +当前版本使用等权器官受累定义： +\[ + O_k(t) = - 1-\prod_{i=0}^{n} - \left[ - 1-p_d\!\left(h(t_i),t_{i+1}-t_i\right) - \right], - \qquad t_{n+1}=t. + 1-\exp\left( + -\sum_{d\in\mathcal{D}_k}\Lambda_d(t) + \right), \] - -该定义只使用每一段历史区间一次，因此避免了从多个历史节点重复预测到同一个查询时刻所造成的重叠计数。 - -\subsection{观测锚定已形成负担} - -观测锚定已形成负担将历史诊断视为事实证据。定义疾病 \(d\) 的历史观测指示变量： +等价于 \[ - o_d(t) - = - \mathbb{I}\left\{ - \exists j:\; \mathrm{event}_j=d,\; \mathrm{time}_j\le t - \right\}. -\] -观测锚定版本定义为 -\[ - z^{\mathrm{obs}}_d(t)=o_d(t). -\] - -该版本最接近 HFRM 等基于诊断代码的负担度量：一旦疾病代码在查询时刻 \(t\) 前出现，对应的疾病负担项即被视为存在。 -它最可审计，也最贴近代码负担定义，但不能区分同一历史诊断在严重程度、发生时间远近和当前残留影响上的差异。 - -\subsection{已形成负担版本选择} - -两个定义对应不同语义： -\[ - z^{\mathrm{obs}}_d(t) - = - \text{观测诊断负担}, -\] -\[ - z^{\mathrm{model}}_d(t) - = - \text{模型加权状态负担}. -\] -当目标是复现或扩展诊断代码负担指标时，应使用观测锚定版本。当目标是让 DeepHealth 根据历史隐含状态轨迹给出连续负担强度时， -应使用模型加权版本。在后续公式中，\(z_d(t)\) 表示根据所选 BI 版本采用的 -\(z^{\mathrm{obs}}_d(t)\) 或 \(z^{\mathrm{model}}_d(t)\)。 - -\subsection{观测锚定与模型加权负担的异同} - -观测锚定和模型加权两个定义具有相同目标：二者都试图刻画查询时刻 \(t\) 之前已经形成的疾病负担，并在此基础上再叠加未来预期负担。 -二者进入后续 BI 公式的方式完全相同，差异只在于如何定义 \(z_d(t)\)。 - -二者的核心区别在于优先采用哪类证据。观测锚定版本以诊断是否真实发生作为主要证据： -\[ - z^{\mathrm{obs}}_d(t)=1 - \quad\text{一旦疾病 } d \text{ 在 } t \text{ 前被观测到。} -\] -这适用于希望 BI 尽量贴近 HFRM 等诊断代码负担指标的场景。它透明、可审计，并且不容易受到模型校准误差影响； -但它会把同一种历史诊断都视为同等程度的已形成负担，不能表达严重程度、发生时间、上下文和残留影响的差异。 - -模型加权版本则以 DeepHealth 的历史风险轨迹作为主要证据： -\[ - z^{\mathrm{model}}_d(t) - = - 1-\prod_i - \left[ - 1-p_d\!\left(h(t_i),t_{i+1}-t_i\right) - \right]. -\] -该版本允许同一种已发生疾病在不同个体、不同时间和不同上下文下具有不同负担强度。例如，extra-info、疾病序列背景和隐含状态轨迹 -都会影响模型给出的区间风险。它可能更接近状态依赖的连续负担强度，但如果模型对某个真实发生过的疾病给出较低历史概率， -也可能低估该诊断事实对应的负担。 - -因此，二者回答的是相关但不完全相同的问题： -\[ - z^{\mathrm{obs}}_d(t): - \text{疾病 } d \text{ 是否已经作为诊断历史的一部分被记录？} -\] -\[ - z^{\mathrm{model}}_d(t): - \text{模型隐含轨迹在多大程度上支持疾病 } d \text{ 已经形成负担？} -\] -因此，这两个版本都应作为有价值的敏感性分析方案。观测锚定版本更适合强调可审计性和与既有代码指标的一致性； -模型加权版本更适合将 DeepHealth 作为连续状态模型，让学习到的历史轨迹调节疾病负担强度。 - -\subsection{累计强度形式} - -定义区间累计风险强度 -\[ - \ell_d(h_i,\Delta_i) - = - -\log\left[1-p_d(h_i,\Delta_i)\right], -\] -以及历史累计强度 -\[ - \Lambda^{\mathrm{model}}_d(t)=\sum_{i=0}^{n}\ell_d(h_i,\Delta_i). -\] -则 -\[ - z^{\mathrm{model}}_d(t)=1-\exp[-\Lambda^{\mathrm{model}}_d(t)]. -\] - -对于 exponential 模型， -\[ - \ell_d(h_i,\Delta_i)=\lambda_d(h_i)\Delta_i, -\] -因此 -\[ - z^{\mathrm{model}}_d(t) - = - 1-\exp\left[ - -\sum_{i=0}^{n} - \lambda_d\!\left(h(t_i)\right)(t_{i+1}-t_i) - \right]. -\] - -对于 Weibull 模型， -\[ - \ell_d(h_i,\Delta_i) - = - \lambda_d(h_i)\Delta_i^{\rho_d(h_i)}, -\] -因此 -\[ - z^{\mathrm{model}}_d(t) - = - 1-\exp\left[ - -\sum_{i=0}^{n} - \lambda_d\!\left(h(t_i)\right) - (t_{i+1}-t_i)^{\rho_d(h(t_i))} - \right]. -\] - -\section{未来预期负担} - -所选择的已形成负担 \(z_d(t)\) 表示截至查询时刻 \(t\) 已经形成的疾病负担。它可以是观测锚定负担 -\(z^{\mathrm{obs}}_d(t)\)，也可以是模型加权负担 \(z^{\mathrm{model}}_d(t)\)。从当前查询时刻 \(t\) 出发， -未来时间窗 \(\tau\) 内的疾病风险为 -\[ - p_d(h(t),\tau). -\] -疾病 \(d\) 的未来预期新增负担定义为 -\[ - f_d(t,\tau) - = - \left[1-z_d(t)\right]p_d(h(t),\tau). -\] -该项只计算尚未形成的疾病负担部分，避免历史负担与未来风险重复计数。疾病 \(d\) 的总动态负担贡献为 -\[ - b_d(t,\tau) - = - z_d(t)+f_d(t,\tau). -\] -等价地， -\[ - b_d(t,\tau) + O_k(t) = 1- - \left[1-z_d(t)\right] - \left[1-p_d(h(t),\tau)\right]. + \prod_{d\in\mathcal{D}_k} + \left[1-z_d(t)\right]. \] -因此，\(b_d(t,\tau)\) 可以解释为疾病 \(d\) 的负担在时刻 \(t\) 已经形成，或将在未来时间窗 \(\tau\) 内新形成的累计概率。 - -\section{负担指数定义} - -设 \(A \in \mathbb{R}_{\ge 0}^{K \times D}\) 是疾病到负担维度的映射矩阵。维度 \(k\) 的历史负担、未来负担和总负担分别为 +因此 \(O_k(t)\in[0,1]\)，表示器官/系统 \(k\) 被至少一个相关疾病过程累及的概率型程度。 +当前所有疾病在同一器官内等权；后续可扩展为带疾病权重的形式： \[ - \operatorname{BI}^{\mathrm{hist}}_k(t) + O_k(t) = - \sum_{d=1}^{D} A_{k,d} z_d(t), -\] -\[ - \operatorname{BI}^{\mathrm{future}}_k(t,\tau) - = - \sum_{d=1}^{D} - A_{k,d} - \left[1-z_d(t)\right]p_d(h(t),\tau), -\] -以及 -\[ - \operatorname{BI}^{\mathrm{total}}_k(t,\tau) - = - \operatorname{BI}^{\mathrm{hist}}_k(t) - + - \operatorname{BI}^{\mathrm{future}}_k(t,\tau). -\] -等价地， -\[ - \operatorname{BI}^{\mathrm{total}}_k(t,\tau) - = - \sum_{d=1}^{D} - A_{k,d} - \left\{ - 1- - \left[1-z_d(t)\right] - \left[1-p_d(h(t),\tau)\right] - \right\}. + 1-\exp\left( + -\sum_{d\in\mathcal{D}_k}\alpha_{k,d}\Lambda_d(t) + \right). \] -对于 OBI，\(A=A^{\mathrm{organ}}\)。对于 FBI，\(A=A^{\mathrm{func}}\)。 +\section{器官列表} -\section{映射矩阵构建} - -\subsection{器官映射矩阵} - -器官映射矩阵应来自代码分类体系或经过验证的临床分组，而不是人为随意指定权重。在当前 ICD token 设置下， -第一版可以使用 ICD 章节或预定义 ICD 范围构建稀疏的疾病到器官 mask： -\[ - M^{\mathrm{organ}}_{k,d}\in\{0,1\}. -\] -示例包括： +当前器官/系统列表参考器官年龄研究中的 organ-age-inspired systems，并结合 ICD 疾病标签空间调整： \begin{center} \begin{tabular}{ll} \toprule -维度 & 示例 ICD 组 \\ +ID & 含义 \\ \midrule -心脏/血管 & I00--I99，可进一步拆分为心脏和血管组 \\ -脑/神经 & G00--G99，F00--F09，I60--I69 \\ -肾脏/泌尿生殖 & N00--N39，尤其 N17--N19 \\ -肺/呼吸 & J00--J99 \\ -代谢/内分泌 & E00--E90 \\ -肝脏/消化 & K00--K93，尤其 K70--K77 \\ -肌骨 & M00--M99 \\ +brain\_neurologic & 脑与神经系统 \\ +heart & 心脏 \\ +artery\_vascular & 动脉与血管系统 \\ +immune & 免疫与感染相关系统 \\ +intestine\_digestive & 肠道与消化系统 \\ +kidney & 肾脏与泌尿系统 \\ +liver & 肝脏 \\ +lung & 肺与呼吸系统 \\ +muscle\_musculoskeletal & 肌肉骨骼系统 \\ +pancreas\_endocrine & 胰腺与内分泌系统 \\ +adipose\_metabolic & 脂肪与代谢系统 \\ +female\_reproductive & 女性生殖系统 \\ +male\_reproductive & 男性生殖系统 \\ +neoplasm & 肿瘤 \\ \bottomrule \end{tabular} \end{center} +肿瘤作为疾病系统单独保留，不强行归入某个单一器官。男女生殖系统单独拆分。 -最简单的器官权重为 +\section{DeepHealth-HFRS 衰弱风险指数} + +原版 UK-HFRS 是二值疾病发生状态的加权和： \[ - A^{\mathrm{organ}}_{k,d}=M^{\mathrm{organ}}_{k,d}. -\] -如果有纵向器官终点标签，可以在 mask 约束下学习权重： -\[ - A^{\mathrm{organ}}_{k,d}\ge 0, + \operatorname{HFRS}^{\mathrm{obs}}(t) + = + \sum_{d\in\mathcal{D}_{\mathrm{HFRS}}} + w^{\mathrm{HFRS}}_d o_d(t), \qquad - A^{\mathrm{organ}}_{k,d}=0 - \quad\text{if}\quad - M^{\mathrm{organ}}_{k,d}=0. + o_d(t)\in\{0,1\}. \] -这样可以保持投影的临床可解释性，同时允许数据驱动校准。 - -\subsection{功能映射矩阵} - -功能映射矩阵应尽可能锚定在经过验证的衰弱相关诊断代码表上。CIHI-HFRM 或相关的 Hospital Frailty Risk Measure -是合适起点，因为它从诊断代码及其权重定义衰弱负担。 - -设 \(w^{\mathrm{HFRM}}_d\ge 0\) 是映射到 DeepHealth 疾病 token \(d\) 的 HFRM 权重。如果 HFRM 代码比 -DeepHealth 的 ICD token 更细，而 DeepHealth 使用三位 ICD token，则可按代码前缀聚合。保守默认方式是 +DeepHealth-HFRS 保留原版 UK-HFRS 权重，只把疾病状态从二值观测替换为连续疾病表达率： \[ - w^{\mathrm{HFRM}}_d + \operatorname{HFRS}^{\mathrm{DH}}(t) = - \max_{c:\, c \text{ maps to token } d} - w^{\mathrm{HFRM}}_c. -\] - -对于总功能负担，一维映射为 -\[ - A^{\mathrm{func,total}}_{1,d} - = - w^{\mathrm{HFRM}}_d. -\] -对于分域功能负担，定义分组 mask -\[ - G_{k,d}\in\{0,1\}, -\] -其中 \(G_{k,d}=1\) 表示 HFRM 相关疾病 token \(d\) 属于功能负担维度 \(k\)。于是 -\[ - A^{\mathrm{func}}_{k,d} - = - G_{k,d} w^{\mathrm{HFRM}}_d. -\] - -候选功能维度包括行动、认知、情绪、感官、营养、感染或免疫脆弱性、功能依赖和共病负担。在没有直接功能测量校准之前， -这些维度应被解释为诊断风险驱动的功能负担代理，而不是直接的功能储备测量。 - -\section{归一化与报告} - -原始负担指数是加权加和： -\[ - \operatorname{BI}_k(t,\tau) - = - \sum_d A_{k,d} b_d(t,\tau). -\] -为了可解释性，系统应报告三项分解： -\[ - \operatorname{BI}^{\mathrm{hist}}_k(t), + \sum_{d\in\mathcal{D}_{\mathrm{HFRS}}} + w^{\mathrm{HFRS}}_d z_d(t), \qquad - \operatorname{BI}^{\mathrm{future}}_k(t,\tau), - \qquad - \operatorname{BI}^{\mathrm{total}}_k(t,\tau). + z_d(t)\in[0,1]. \] +因此 DeepHealth-HFRS 仍然可以称为衰弱风险指数；它是原版 HFRS 的自然连续化。 -也可以报告归一化负担： +\section{当前实现} + +当前代码只计算历史当前状态，不再使用未来 horizon。每个 landmark age \(t\) 输出： +\begin{itemize}[leftmargin=*] + \item 内部疾病表达率 \(z_d(t)\)； + \item 等权器官受累指数 \(O_k(t)\)； + \item DeepHealth-HFRS 衰弱风险指数 \(\operatorname{HFRS}^{\mathrm{DH}}(t)\)。 +\end{itemize} +输出表使用 \[ - \widetilde{\operatorname{BI}}_k(t,\tau) - = - \frac{ - \sum_d A_{k,d} b_d(t,\tau) - }{ - \sum_d A_{k,d} + \epsilon - }, + \texttt{index\_type},\quad + \texttt{index\_id},\quad + \texttt{index\_label},\quad + \texttt{index\_value}. \] -其中 \(\epsilon>0\) 用于避免除零。当 \(b_d(t,\tau)\in[0,1]\) 且 \(A_{k,d}\ge 0\) 时，该分数便于不同维度之间比较。 - -在队列层面，还可以在年龄和性别分层参考人群中计算相对分位数： -\[ - \operatorname{PercentileBI}_k(t,\tau) - = - \operatorname{rank}_{\mathrm{age,sex}} - \left( - \operatorname{BI}^{\mathrm{total}}_k(t,\tau) - \right). -\] -该分位数表示相对负担排名，而不是健康储备百分比。 - -\section{验证} - -OBI 与 FBI 应使用不同结局进行验证。 - -OBI 应针对器官系统特异性未来事件验证。例如，心脏/血管负担对应心血管事件，脑/神经负担对应卒中或痴呆， -肾脏负担对应 CKD 进展，肺部负担对应呼吸系统事件。 - -FBI 应针对 CIHI-HFRM 风格的衰弱诊断负担、衰弱相关诊断终点、住院、死亡、照护依赖代理指标， -或在条件允许时针对直接功能结局验证。如果没有 ADL/IADL、步速、握力、认知测验或恢复能力等直接功能标签， -FBI 应被报告为基于诊断风险的功能负担代理，而不是直接的功能储备测量。 - -\section{总结} - -DeepHealth 负担指数将疾病级风险预测转换为可解释的负担表征。已形成负担可以定义为观测锚定负担 -\(z^{\mathrm{obs}}_d(t)\)，即遵循真实历史诊断；也可以定义为模型加权负担 \(z^{\mathrm{model}}_d(t)\)， -即沿历史隐含状态轨迹累积 DeepHealth 预测的区间风险。未来预期负担则是在尚未形成的疾病负担部分上计算未来新增风险。 -OBI 使用解剖系统分组描述病理负担集中在哪里；FBI 使用 CIHI-HFRM 风格的衰弱相关诊断权重描述功能脆弱性负担。 -二者提供疾病负担的两种互补视角，同时允许明确选择已形成负担的语义。 \end{document} diff --git a/cihi_hfrm_label_mapping.csv b/cihi_hfrm_label_mapping.csv deleted file mode 100644 index ffa90b3..0000000 --- a/cihi_hfrm_label_mapping.csv +++ /dev/null @@ -1,306 +0,0 @@ -token_id,label_code,label_name,hfrm_category_id,hfrm_category,hfrm_key_area,hfrm_category_weight,hfrm_normalized_weight,n_matched_hfrm_codes,matched_hfrm_codes,matched_hfrm_code_descriptions,match_types,source_pdf -7,A04,(other bacterial intestinal infections),20,Infections,Other,1.0,0.027777777777777776,1,A04,A04: Other bacterial intestinal infections,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -11,A08,(viral and other specified intestinal infections),20,Infections,Other,1.0,0.027777777777777776,1,A08,A08: Viral and other specified intestinal infections,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -12,A09,(diarrhoea and gastro-enteritis of presumed infectious origin),16,Gastrointestinal,Morbidity,1.0,0.027777777777777776,1,A09,A09: Other gastroenteritis and colitis of infectious and,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -35,A40,(streptococcal septicaemia),20,Infections,Other,1.0,0.027777777777777776,1,A40,A40: Streptococcal sepsis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -36,A41,(other septicaemia),20,Infections,Other,1.0,0.027777777777777776,1,A41,A41: Other sepsis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -41,A48,"(other bacterial diseases, not elsewhere classified)",20,Infections,Other,1.0,0.027777777777777776,1,A48.8,A48.8: Other specified bacterial diseases,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -42,A49,(bacterial infection of unspecified site),20,Infections,Other,1.0,0.027777777777777776,5,A49.0;A49.1;A49.2;A49.8;A49.9,"A49.0: Staphylococcal infection, unspecified site | A49.1: Streptococcal and enterococcal infection, unspecified site | A49.2: Haemophilus influenzae infection, unspecified site | A49.8: Other bacterial infections of unspecified site | A49.9: Bacterial infection, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -158,B95,(streptococcus and staphylococcus as the cause of diseases classified to other chapters),20,Infections,Other,1.0,0.027777777777777776,1,B95,B95: Streptococcus and staphylococcus as the cause of disease,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -159,B96,(other bacterial agents as the cause of diseases classified to other chapters),20,Infections,Other,1.0,0.027777777777777776,1,B96,B96: Other specified bacterial agents as the cause of diseases,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -160,B97,(viral agents as the cause of diseases classified to other chapters),20,Infections,Other,1.0,0.027777777777777776,1,B97,B97: Viral agents as the cause of diseases classified to,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -176,D64,(other anaemias),1,Anemia,Morbidity,1.0,0.027777777777777776,1,D64,D64: Other anaemias,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -198,E02,(subclinical iodine-deficiency hypothyroidism),11,Endocrine,Other,1.0,0.027777777777777776,1,E02,E02: Subclinical iodine-deficiency hypothyroidism,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -199,E03,(other hypothyroidism),11,Endocrine,Other,1.0,0.027777777777777776,1,E03,E03: Other hypothyroidism,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -200,E04,(other non-toxic goitre),11,Endocrine,Other,1.0,0.027777777777777776,1,E04,E04: Other nontoxic goitre,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -201,E05,(thyrotoxicosis [hyperthyroidism]),11,Endocrine,Other,1.0,0.027777777777777776,1,E05,E05: Thyrotoxicosis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -202,E06,(thyroiditis),11,Endocrine,Other,1.0,0.027777777777777776,1,E06,E06: Thyroiditis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -203,E07,(other disorders of thyroid),11,Endocrine,Other,1.0,0.027777777777777776,1,E07,E07: Other disorders of thyroid,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -204,E10,(insulin-dependent diabetes mellitus),9,Diabetes,Morbidity,1.0,0.027777777777777776,1,E10,E10: Type 1 diabetes mellitus,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -205,E11,(non-insulin-dependent diabetes mellitus),9,Diabetes,Morbidity,1.0,0.027777777777777776,1,E11,E11: Type 2 diabetes mellitus,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -207,E13,(other specified diabetes mellitus),9,Diabetes,Morbidity,1.0,0.027777777777777776,1,E13,E13: Other specified diabetes mellitus,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -208,E14,(unspecified diabetes mellitus),9,Diabetes,Morbidity,1.0,0.027777777777777776,1,E14,E14: Unspecified diabetes mellitus,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -210,E16,(other disorders of pancreatic internal secretion),11,Endocrine,Other,1.0,0.027777777777777776,1,E16,E16: Other disorders of pancreatic internal secretion,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -211,E20,(hypoparathyroidism),11,Endocrine,Other,1.0,0.027777777777777776,1,E20.9,"E20.9: Hypoparathyroidism, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -212,E21,(hyperparathyroidism and other disorders of parathyroid gland),11,Endocrine,Other,1.0,0.027777777777777776,5,E21.0;E21.1;E21.2;E21.3;E21.4,"E21.0: Primary hyperparathyroidism | E21.1: Secondary hyperparathyroidism, not elsewhere classified | E21.2: Other hyperparathyroidism | E21.3: Hyperparathyroidism, unspecified | E21.4: Other specified disorders of parathyroid gland",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -213,E22,(hyperfunction of pituitary gland),11,Endocrine,Other,1.0,0.027777777777777776,1,E22.2,E22.2: Syndrome of inappropriate secretions of antidiuretic hormone,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -214,E23,(hypofunction and other disorders of pituitary gland),11,Endocrine,Other,1.0,0.027777777777777776,2,E23.0;E23.2,E23.0: Hypopituitarism | E23.2: Diabetes insipidus,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -218,E27,(other disorders of adrenal gland),11,Endocrine,Other,1.0,0.027777777777777776,7,E27.1;E27.2;E27.3;E27.4;E27.5;E27.8;E27.9,"E27.1: Primary adrenocortical insufficiency | E27.2: Addisonian crisis | E27.3: Drug-induced adrenocortical insufficiency | E27.4: Other and unspecified adrenocortical insufficiency | E27.5: Adrenomedullary hyperfunction | E27.8: Other specified disorders of adrenal gland | E27.9: Disorder of adrenal gland, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -223,E32,(diseases of thymus),11,Endocrine,Other,1.0,0.027777777777777776,1,E32.8,E32.8: Other diseases of thymus,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -224,E34,(other endocrine disorders),11,Endocrine,Other,1.0,0.027777777777777776,2,E34.0;E34.9,"E34.0: Carcinoid syndrome | E34.9: Endocrine disorder, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -226,E41,(nutritional marasmus),25,Nutrition and wasting,Other,1.0,0.027777777777777776,1,E41,E41: Nutritional marasmus,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -227,E43,(unspecified severe protein-energy malnutrition),25,Nutrition and wasting,Other,1.0,0.027777777777777776,1,E43,E43: Unspecified severe protein-energy malnutrition,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -228,E44,(protein-energy malnutrition of moderate and mild degree),25,Nutrition and wasting,Other,1.0,0.027777777777777776,2,E44.0;E44.1,E44.0: Moderate protein-energy malnutrition | E44.1: Mild protein-energy malnutrition,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -230,E46,(unspecified protein-energy malnutrition),25,Nutrition and wasting,Other,1.0,0.027777777777777776,1,E46,E46: Unspecified protein-energy malnutrition,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -234,E53,(deficiency of other b group vitamins),25,Nutrition and wasting,Other,1.0,0.027777777777777776,1,E53,E53: Deficiency of other B group vitamins,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -236,E55,(vitamin d deficiency),25,Nutrition and wasting,Other,1.0,0.027777777777777776,1,E55,E55: Vitamin D deficiency,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -242,E63,(other nutritional deficiencies),25,Nutrition and wasting,Other,1.0,0.027777777777777776,1,E63.9,"E63.9: Nutritional deficiency, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -259,E83,(disorders of mineral metabolism),25,Nutrition and wasting,Other,1.0,0.027777777777777776,1,E83,E83: Disorders of mineral metabolism,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -261,E85,(amyloidosis),28,Other frailty conditions and diseases,Other,1.0,0.027777777777777776,3,E85.3;E85.4;E85.9,"E85.3: Secondary systemic amyloidosis | E85.4: Organ-limited amyloidosis | E85.9: Amyloidosis, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -262,E86,(volume depletion),25,Nutrition and wasting,Other,1.0,0.027777777777777776,1,E86,E86: Volume depletion,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -263,E87,"(other disorders of fluid, electrolyte and acid-base balance)",25,Nutrition and wasting,Other,1.0,0.027777777777777776,1,E87,"E87: Other disorders of fluid, electrolyte, and acid-base balance",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -266,F00,(dementia in alzheimer's disease),8,Dementia and Alzheimer's,Cognition and mood,1.0,0.027777777777777776,1,F00,F00: Dementia in Alzheimer’s disease,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -267,F01,(vascular dementia),8,Dementia and Alzheimer's,Cognition and mood,1.0,0.027777777777777776,1,F01,F01: Vascular dementia,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -268,F02,(dementia in other diseases classified elsewhere),8,Dementia and Alzheimer's,Cognition and mood,1.0,0.027777777777777776,1,F02,F02: Dementia in other diseases classified elsewhere,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -269,F03,(unspecified dementia),8,Dementia and Alzheimer's,Cognition and mood,1.0,0.027777777777777776,1,F03,F03: Unspecified dementia,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -271,F05,"(delirium, not induced by alcohol and other psychoactive substances)",6,Delirium,Cognition and mood,1.0,0.027777777777777776,1,F05,"F05: Delirium, not induced by alcohol and other",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -272,F06,(other mental disorders due to brain damage and dysfunction and to physical disease),12,Epilepsy,Other,1.0,0.027777777777777776,1,F06.8,F06.8: Other specified mental disorders due to brain damage,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -272,F06,(other mental disorders due to brain damage and dysfunction and to physical disease),27,Other cognitive disorders,Cognition and mood,1.0,0.027777777777777776,1,F06.7,F06.7: Mild cognitive disorder,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -278,F13,(mental and behavioural disorders due to use of sedatives or hypnotics),6,Delirium,Cognition and mood,1.0,0.027777777777777776,1,F13.4,F13.4: Mental and behavioral disorders due to use of sedatives,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -287,F22,(persistent delusional disorders),7,Delusions and hallucinations,Cognition and mood,1.0,0.027777777777777776,1,F22,F22: Persistent delusional disorders,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -295,F32,(depressive episode),22,Mood disorders,Cognition and mood,1.0,0.027777777777777776,1,F32,F32: Depressive episode,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -301,F41,(other anxiety disorders),22,Mood disorders,Cognition and mood,1.0,0.027777777777777776,1,F41,F41: Other anxiety disorders,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -305,F45,(somatoform disorders),30,Pain,Other,1.0,0.027777777777777776,1,F45.4,F45.4: Persistent somatoform pain disorder,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -328,F80,(specific developmental disorders of speech and language),27,Other cognitive disorders,Cognition and mood,1.0,0.027777777777777776,3,F80.1;F80.2;F80.3,F80.1: Expressive language disorder | F80.2: Receptive language disorder | F80.3: Acquired aphasia with epilepsy [Landau-Kleffner],hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -355,G12,(spinal muscular atrophy and related syndromes),28,Other frailty conditions and diseases,Other,1.0,0.027777777777777776,1,G12.20,G12.20: Amyotrophic lateral sclerosis,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -358,G20,(parkinson's disease),28,Other frailty conditions and diseases,Other,1.0,0.027777777777777776,1,G20,G20: Parkinson’s disease,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -359,G21,(secondary parkinsonism),28,Other frailty conditions and diseases,Other,1.0,0.027777777777777776,1,G21,G21: Secondary parkinsonism,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -360,G22,(parkinsonism in diseases classified elsewhere),28,Other frailty conditions and diseases,Other,1.0,0.027777777777777776,1,G22,G22: Parkinsonism in diseases classified elsewhere,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -364,G30,(alzheimer's disease),8,Dementia and Alzheimer's,Cognition and mood,1.0,0.027777777777777776,1,G30,G30: Alzheimer’s disease,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -365,G31,"(other degenerative diseases of nervous system, not elsewhere classified)",8,Dementia and Alzheimer's,Cognition and mood,1.0,0.027777777777777776,3,G31.00;G31.02;G31.1,"G31.00: Pick’s disease | G31.02: Frontal lobe dementia | G31.1: Senile degeneration of brain, not elsewhere specified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -365,G31,"(other degenerative diseases of nervous system, not elsewhere classified)",27,Other cognitive disorders,Cognition and mood,1.0,0.027777777777777776,1,G31.01,G31.01: Progressive isolated aphasia [Mesulam],hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -367,G35,(multiple sclerosis),28,Other frailty conditions and diseases,Other,1.0,0.027777777777777776,1,G35,G35: Multiple sclerosis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -370,G40,(epilepsy),12,Epilepsy,Other,1.0,0.027777777777777776,1,G40,G40: Epilepsy,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -374,G45,(transient cerebral ischaemic attacks and related syndromes),5,Cerebrovascular,Morbidity,1.0,0.027777777777777776,1,G45,G45: Transient cerebral ischaemic attacks and related syndromes,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -376,G47,(sleep disorders),27,Other cognitive disorders,Cognition and mood,1.0,0.027777777777777776,5,G47.0;G47.1;G47.2;G47.8;G47.9,"G47.0: Disorders of initiating and maintaining sleep | G47.1: Disorders of excessive somnolence [hypersomnias] | G47.2: Disorders of the sleep-wake schedule | G47.8: Other sleep disorders | G47.9: Sleep disorder, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -377,G50,(disorders of trigeminal nerve),30,Pain,Other,1.0,0.027777777777777776,1,G50.0,G50.0: Trigeminal neuralgia,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -397,G81,(hemiplegia),23,Movement and immobility,Function,1.0,0.027777777777777776,1,G81,G81: Hemiplegia,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -398,G82,(paraplegia and tetraplegia),23,Movement and immobility,Function,1.0,0.027777777777777776,1,G82,G82: Paraplegia and tetraplegia,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -439,H40,(glaucoma),33,Sensory impairment,Sensory loss,1.0,0.027777777777777776,1,H40,H40: Glaucoma,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -440,H42,(glaucoma in diseases classified elsewhere),33,Sensory impairment,Sensory loss,1.0,0.027777777777777776,1,H42,H42: Glaucoma in diseases classified elsewhere,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -451,H53,(visual disturbances),33,Sensory impairment,Sensory loss,1.0,0.027777777777777776,1,H53,H53: Visual disturbances,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -452,H54,(blindness and low vision),33,Sensory impairment,Sensory loss,1.0,0.027777777777777776,1,H54,H54: Visual impairment including blindness,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -454,H57,(other disorders of eye and adnexa),30,Pain,Other,1.0,0.027777777777777776,1,H57.1,H57.1: Ocular pain,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -472,H81,(disorders of vestibular function),23,Movement and immobility,Function,1.0,0.027777777777777776,1,H81,H81: Disorders of vestibular function,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -474,H83,(other diseases of inner ear),33,Sensory impairment,Sensory loss,1.0,0.027777777777777776,1,H83.3,H83.3: Noise effects on inner ear,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -476,H91,(other hearing loss),33,Sensory impairment,Sensory loss,1.0,0.027777777777777776,1,H91,H91: Other hearing loss,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -477,H92,(otalgia and effusion of ear),30,Pain,Other,1.0,0.027777777777777776,1,H92.0,H92.0: Otalgia,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -484,I05,(rheumatic mitral valve diseases),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I05,I05: Rheumatic mitral valve diseases,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -485,I06,(rheumatic aortic valve diseases),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I06,I06: Rheumatic aortic valve diseases,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -486,I07,(rheumatic tricuspid valve diseases),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I07,I07: Rheumatic tricuspid valve diseases,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -487,I08,(multiple valve diseases),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I08,I08: Multiple valve diseases,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -488,I09,(other rheumatic heart diseases),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I09.0,I09.0: Rheumatic myocarditis,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -489,I10,(essential (primary) hypertension),18,Hypo- and hypertension,Morbidity,1.0,0.027777777777777776,1,I10,I10: Essential (primary) hypertension,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -490,I11,(hypertensive heart disease),18,Hypo- and hypertension,Morbidity,1.0,0.027777777777777776,1,I11,I11: Hypertensive heart disease,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -491,I12,(hypertensive renal disease),18,Hypo- and hypertension,Morbidity,1.0,0.027777777777777776,1,I12,I12: Hypertensive renal disease,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -492,I13,(hypertensive heart and renal disease),18,Hypo- and hypertension,Morbidity,1.0,0.027777777777777776,1,I13,I13: Hypertensive heart and renal disease,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -493,I15,(secondary hypertension),18,Hypo- and hypertension,Morbidity,1.0,0.027777777777777776,1,I15,I15: Secondary hypertension,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -499,I25,(chronic ischaemic heart disease),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I25.1,I25.1: Atherosclerotic heart disease,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -500,I26,(pulmonary embolism),34,Thrombosis and embolism,Morbidity,1.0,0.027777777777777776,1,I26,I26: Pulmonary embolism,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -507,I34,(nonrheumatic mitral valve disorders),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I34,I34: Nonrheumatic mitral valve disorders,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -508,I35,(nonrheumatic aortic valve disorders),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I35,I35: Nonrheumatic aortic valve disorders,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -509,I36,(nonrheumatic tricuspid valve disorders),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I36,I36: Nonrheumatic tricuspid valve disorders,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -510,I37,(pulmonary valve disorders),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I37,I37: Pulmonary valve disorders,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -511,I38,"(endocarditis, valve unspecified)",4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I38,"I38: Endocarditis, valve unspecified",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -512,I39,(endocarditis and heart valve disorders in diseases classified elsewhere),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I39,I39: Endocarditis and heart valve disorders in diseases,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -515,I42,(cardiomyopathy),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I42,I42: Cardiomyopathy,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -516,I43,(cardiomyopathy in diseases classified elsewhere),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I43,I43: Cardiomyopathy in diseases classified elsewhere,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -520,I47,(paroxysmal tachycardia),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I47,I47: Paroxysmal tachycardia,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -521,I48,(atrial fibrillation and flutter),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I48,I48: Atrial fibrillation and flutter,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -522,I49,(other cardiac arrhythmias),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I49,I49: Other cardiac arrhythmias,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -523,I50,(heart failure),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,3,I50.0;I50.1;I50.9,"I50.0: Congestive heart failure | I50.1: Left ventricular failure | I50.9: Heart failure, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -526,I60,(subarachnoid haemorrhage),5,Cerebrovascular,Morbidity,1.0,0.027777777777777776,1,I60,I60: Subarachnoid haemorrhage,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -527,I61,(intracerebral haemorrhage),5,Cerebrovascular,Morbidity,1.0,0.027777777777777776,1,I61,I61: Intracerebral haemorrhage,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -529,I63,(cerebral infarction),5,Cerebrovascular,Morbidity,1.0,0.027777777777777776,8,I63.0;I63.1;I63.2;I63.3;I63.4;I63.5;I63.8;I63.9,"I63.0: Cerebral infarction due to thrombosis of precerebral arteries | I63.1: Cerebral infarction due to embolism of precerebral arteries | I63.2: Cerebral infarction due to unspecified occlusion or stenosis | I63.3: Cerebral infarction due to thrombosis of cerebral arteries | I63.4: Cerebral infarction due to embolism of cerebral arteries | I63.5: Cerebral infarction due to unspecified occlusion or stenosis | I63.8: Other cerebral infarction | I63.9: Cerebral infarction, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -530,I64,"(stroke, not specified as haemorrhage or infarction)",5,Cerebrovascular,Morbidity,1.0,0.027777777777777776,1,I64,"I64: Stroke, not specified as haemorrhage or infarction",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -535,I69,(sequelae of cerebrovascular disease),5,Cerebrovascular,Morbidity,1.0,0.027777777777777776,1,I69,I69: Sequelae of cerebrovascular disease,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -536,I70,(atherosclerosis),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I70,I70: Atherosclerosis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -537,I71,(aortic aneurysm and dissection),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,4,I71.3;I71.4;I71.5;I71.6,"I71.3: Abdominal aortic aneurysm, ruptured | I71.4: Abdominal aortic aneurysm, without mention of rupture | I71.5: Thoracoabdominal aortic aneurysm, ruptured | I71.6: Thoracoabdominal aortic aneurysm, without mention",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -538,I72,(other aneurysm),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,4,I72.1;I72.2;I72.3;I72.4,I72.1: Aneurysm and dissection of artery of upper extremity | I72.2: Aneurysm and dissection of renal artery | I72.3: Aneurysm and dissection of iliac artery | I72.4: Aneurysm and dissection of artery of lower extremity,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -539,I73,(other peripheral vascular diseases),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,I73,I73: Other peripheral vascular diseases,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -544,I80,(phlebitis and thrombophlebitis),34,Thrombosis and embolism,Morbidity,1.0,0.027777777777777776,1,I80,I80: Phlebitis and thrombophlebitis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -545,I81,(portal vein thrombosis),34,Thrombosis and embolism,Morbidity,1.0,0.027777777777777776,1,I81,I81: Portal vein thrombosis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -546,I82,(other venous embolism and thrombosis),34,Thrombosis and embolism,Morbidity,1.0,0.027777777777777776,4,I82.2;I82.3;I82.8;I82.9,I82.2: Embolism and thrombosis of vena cava | I82.3: Embolism and thrombosis of renal vein | I82.8: Embolism and thrombosis of other specified veins | I82.9: Embolism and thrombosis of unspecified vein,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -554,I95,(hypotension),18,Hypo- and hypertension,Morbidity,1.0,0.027777777777777776,1,I95,I95: Hypotension,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -587,J39,(other diseases of upper respiratory tract),30,Pain,Other,1.0,0.027777777777777776,1,J39.2,J39.2: Other diseases of pharynx,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -588,J40,"(bronchitis, not specified as acute or chronic)",32,Respiratory,Morbidity,1.0,0.027777777777777776,1,J40,"J40: Bronchitis, not specified as acute or chronic",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -589,J41,(simple and mucopurulent chronic bronchitis),32,Respiratory,Morbidity,1.0,0.027777777777777776,1,J41,J41: Simple and mucopurulent chronic bronchitis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -590,J42,(unspecified chronic bronchitis),32,Respiratory,Morbidity,1.0,0.027777777777777776,1,J42,J42: Unspecified chronic bronchitis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -591,J43,(emphysema),32,Respiratory,Morbidity,1.0,0.027777777777777776,1,J43,J43: Emphysema,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -592,J44,(other chronic obstructive pulmonary disease),32,Respiratory,Morbidity,1.0,0.027777777777777776,1,J44,J44: Other chronic obstructive pulmonary disease,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -593,J45,(asthma),32,Respiratory,Morbidity,1.0,0.027777777777777776,1,J45,J45: Asthma,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -595,J47,(bronchiectasis),32,Respiratory,Morbidity,1.0,0.027777777777777776,1,J47,J47: Bronchiectasis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -604,J69,(pneumonitis due to solids and liquids),32,Respiratory,Morbidity,1.0,0.027777777777777776,1,J69,J69: Pneumonitis due to solids and liquids,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -618,J96,"(respiratory failure, not elsewhere classified)",32,Respiratory,Morbidity,1.0,0.027777777777777776,1,J96,"J96: Respiratory failure, not elsewhere classified",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -631,K10,(other diseases of jaws),30,Pain,Other,1.0,0.027777777777777776,1,K10.8,K10.8: Other specified diseases of jaws,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -634,K13,(other diseases of lip and oral mucosa),30,Pain,Other,1.0,0.027777777777777776,1,K13.7,K13.7: Other and unspecified lesions of oral mucosa,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -635,K14,(diseases of tongue),30,Pain,Other,1.0,0.027777777777777776,1,K14.6,K14.6: Glossodynia,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -641,K26,(duodenal ulcer),16,Gastrointestinal,Morbidity,1.0,0.027777777777777776,1,K26,K26: Duodenal ulcer,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -644,K29,(gastritis and duodenitis),25,Nutrition and wasting,Other,1.0,0.027777777777777776,1,K29.0,K29.0: Acute haemorrhagic gastritis,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -660,K52,(other non-infective gastro-enteritis and colitis),16,Gastrointestinal,Morbidity,1.0,0.027777777777777776,1,K52,K52: Other noninfective gastroenteritis and colitis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -661,K55,(vascular disorders of intestine),4,Cardiac and vascular,Morbidity,1.0,0.027777777777777776,1,K55.1,K55.1: Chronic vascular disorders of intestine,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -665,K59,(other functional intestinal disorders),16,Gastrointestinal,Morbidity,1.0,0.027777777777777776,1,K59,K59: Other functional intestinal disorders,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -668,K62,(other diseases of anus and rectum),30,Pain,Other,1.0,0.027777777777777776,1,K62.8,K62.8: Other specified diseases of anus and rectum,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -696,L03,(cellulitis),20,Infections,Other,1.0,0.027777777777777776,1,L03,L03: Cellulitis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -699,L08,(other local infections of skin and subcutaneous tissue),20,Infections,Other,1.0,0.027777777777777776,1,L08,L08: Other local infections of skin and subcutaneous tissue,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -754,L89,(decubitus ulcer),35,Ulcers and soft tissue disorders,Other,1.0,0.027777777777777776,1,L89,L89: Decubitus [pressure] ulcer and pressure area,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -761,L97,"(ulcer of lower limb, not elsewhere classified)",35,Ulcers and soft tissue disorders,Other,1.0,0.027777777777777776,1,L97,"L97: Ulcer of the lower limb, not elsewhere classified",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -762,L98,"(other disorders of skin and subcutaneous tissue, not elsewhere classified)",35,Ulcers and soft tissue disorders,Other,1.0,0.027777777777777776,3,L98.4;L98.8;L98.9,"L98.4: Chronic ulcer of skin, not elsewhere classified | L98.8: Other specified disorders of skin and subcutaneous tissue | L98.9: Disorder of skin and subcutaneous tissue, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -766,M02,(reactive arthropathies),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M02,M02: Reactive arthropathies,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -767,M03,(postinfective and reactive arthropathies in diseases classified elsewhere),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M03,M03: Postinfective and reactive arthropathies in diseases,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -768,M05,(seropositive rheumatoid arthritis),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M05,M05: Seropositive rheumatoid arthritis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -769,M06,(other rheumatoid arthritis),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M06,M06: Other rheumatoid arthritis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -770,M07,(psoriatic and enteropathic arthropathies),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M07,M07: Psoriatic and enteropathic arthropathies,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -773,M10,(gout),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M10,M10: Gout,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -774,M11,(other crystal arthropathies),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M11,M11: Other crystal arthropathies,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -775,M12,(other specific arthropathies),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,4,M12.0;M12.3;M12.5;M12.8,"M12.0: Chronic postrheumatic arthropathy [Jaccoud] | M12.3: Palindromic rheumatism | M12.5: Traumatic arthropathy | M12.8: Other specific arthropathies, not elsewhere classified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -776,M13,(other arthritis),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,4,M13.0;M13.1;M13.8;M13.9,"M13.0: Polyarthritis, unspecified | M13.1: Monoarthritis, not elsewhere classified | M13.8: Other specified arthritis | M13.9: Arthritis, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -777,M14,(arthropathies in other diseases classified elsewhere),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M14,M14: Arthropathies in other diseases classified elsewhere,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -778,M15,(polyarthrosis),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M15,M15: Polyarthrosis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -779,M16,(coxarthrosis [arthrosis of hip]),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M16,M16: Coxarthrosis [arthrosis of hip],exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -780,M17,(gonarthrosis [arthrosis of knee]),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M17,M17: Gonarthrosis [arthrosis of knee],exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -781,M18,(arthrosis of first carpometacarpal joint),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M18,M18: Arthrosis of first carpometacarpal joint,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -782,M19,(other arthrosis),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M19,M19: Other arthrosis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -788,M25,"(other joint disorders, not elsewhere classified)",24,Musculoskeletal,Function,1.0,0.027777777777777776,1,M25,"M25: Other joint disorders, not elsewhere classified",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -788,M25,"(other joint disorders, not elsewhere classified)",30,Pain,Other,1.0,0.027777777777777776,1,M25.5,M25.5: Pain in joint,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -790,M31,(other necrotising vasculopathies),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M31.5,M31.5: Giant cell arteritis with polymyalgia rheumatica,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -791,M32,(systemic lupus erythematosus),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M32,M32: Systematic lupus erythematosus,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -792,M33,(dermatopolymyositis),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M33,M33: Dermatopolymyositis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -793,M34,(systemic sclerosis),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M34,M34: Systemic sclerosis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -794,M35,(other systemic involvement of connective tissue),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,3,M35.1;M35.2;M35.3,M35.1: Other overlap syndromes | M35.2: Behçet’s disease | M35.3: Polymyalgia rheumatica,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -795,M36,(systemic disorders of connective tissue in diseases classified elsewhere),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,4,M36.0;M36.1;M36.2;M36.3,M36.0: Dermato(poly)myositis in neoplastic disease | M36.1: Arthropathy in neoplastic disease | M36.2: Haemophilic arthropathy | M36.3: Arthropathy in other blood disorders,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -797,M41,(scoliosis),24,Musculoskeletal,Function,1.0,0.027777777777777776,1,M41,M41: Scoliosis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -800,M45,(ankylosing spondylitis),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M45,M45: Ankylosing spondylitis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -801,M46,(other inflammatory spondylopathies),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,2,M46.5;M46.9,"M46.5: Other infective spondylopathies | M46.9: Inflammatory spondylopathy, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -803,M48,(other spondylopathies),24,Musculoskeletal,Function,1.0,0.027777777777777776,1,M48,M48: Other spondylopathies,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -808,M54,(dorsalgia),30,Pain,Other,1.0,0.027777777777777776,7,M54.2;M54.3;M54.4;M54.5;M54.6;M54.8;M54.9,"M54.2: Cervicalgia | M54.3: Sciatica | M54.4: Lumbago with sciatica | M54.5: Low back pain | M54.6: Pain in thoracic spine | M54.8: Other dorsalgia | M54.9: Dorsalgia, unspecified site",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -811,M62,(other disorders of muscle),23,Movement and immobility,Function,1.0,0.027777777777777776,1,M62.3,M62.3: Immobility syndrome (paraplegic),hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -811,M62,(other disorders of muscle),25,Nutrition and wasting,Other,1.0,0.027777777777777776,1,M62.5,"M62.5: Muscle wasting and atrophy, not elsewhere classified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -821,M75,(shoulder lesions),2,Arthritis and inflammation,Function,1.0,0.027777777777777776,1,M75.0,M75.0: Adhesive capsulitis of shoulder,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -824,M79,"(other soft tissue disorders, not elsewhere classified)",30,Pain,Other,1.0,0.027777777777777776,3,M79.1;M79.2;M79.6,"M79.1: Myalgia | M79.2: Neuralgia and neuritis, unspecified | M79.6: Pain in limb",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -824,M79,"(other soft tissue disorders, not elsewhere classified)",35,Ulcers and soft tissue disorders,Other,1.0,0.027777777777777776,1,M79,"M79: Other soft tissue disorders, not elsewhere classified",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -825,M80,(osteoporosis with pathological fracture),14,Fractures and osteoporosis,Function,1.0,0.027777777777777776,1,M80,M80: Osteoporosis with pathological fracture,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -826,M81,(osteoporosis without pathological fracture),14,Fractures and osteoporosis,Function,1.0,0.027777777777777776,1,M81,M81: Osteoporosis without pathological fracture,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -827,M82,(osteoporosis in diseases classified elsewhere),14,Fractures and osteoporosis,Function,1.0,0.027777777777777776,1,M82,M82: Osteoporosis in diseases classified elsewhere,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -834,M89,(other disorders of bone),30,Pain,Other,1.0,0.027777777777777776,1,M89.8,M89.8: Other specified disorders of bone,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -835,M90,(osteopathies in diseases classified elsewhere),14,Fractures and osteoporosis,Function,1.0,0.027777777777777776,1,M90.7,M90.7: Fracture of bone in neoplastic disease,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -843,N00,(acute nephritic syndrome),31,Renal,Morbidity,1.0,0.027777777777777776,1,N00,N00: Acute nephritic syndrome,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -844,N01,(rapidly progressive nephritic syndrome),31,Renal,Morbidity,1.0,0.027777777777777776,1,N01,N01: Rapidly progressive nephritic syndrome,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -845,N02,(recurrent and persistent haematuria),31,Renal,Morbidity,1.0,0.027777777777777776,1,N02,N02: Recurrent and persistent haematuria,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -846,N03,(chronic nephritic syndrome),31,Renal,Morbidity,1.0,0.027777777777777776,1,N03,N03: Chronic nephritic syndrome,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -847,N04,(nephrotic syndrome),31,Renal,Morbidity,1.0,0.027777777777777776,1,N04,N04: Nephrotic syndrome,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -848,N05,(unspecified nephritic syndrome),31,Renal,Morbidity,1.0,0.027777777777777776,1,N05,N05: Unspecified nephritic syndrome,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -849,N06,(isolated proteinuria with specified morphological lesion),31,Renal,Morbidity,1.0,0.027777777777777776,1,N06,N06: Isolated proteinuria with specified morphological lesion,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -850,N07,"(hereditary nephropathy, not elsewhere classified)",31,Renal,Morbidity,1.0,0.027777777777777776,1,N07,"N07: Hereditary nephropathy, not elsewhere classified",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -851,N08,(glomerular disorders in diseases classified elsewhere),31,Renal,Morbidity,1.0,0.027777777777777776,1,N08,N08: Glomerular disorders in diseases classified elsewhere,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -852,N10,(acute tubulo-interstitial nephritis),31,Renal,Morbidity,1.0,0.027777777777777776,1,N10,N10: Acute tubulo-interstitial nephritis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -853,N11,(chronic tubulo-interstitial nephritis),31,Renal,Morbidity,1.0,0.027777777777777776,1,N11,N11: Chronic tubulo-interstitial nephritis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -854,N12,"(tubulo-interstitial nephritis, not specified as acute or chronic)",31,Renal,Morbidity,1.0,0.027777777777777776,1,N12,"N12: Tubulo-interstitial nephritis, not specified as acute or chronic",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -855,N13,(obstructive and reflux uropathy),31,Renal,Morbidity,1.0,0.027777777777777776,1,N13,N13: Obstructive and reflux uropathy,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -856,N14,(drug- and heavy-metal-induced tubulo-interstitial and tubular conditions),31,Renal,Morbidity,1.0,0.027777777777777776,1,N14,N14: Drug and heavy-metal-induced tubulo-interstitial,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -857,N15,(other renal tubulo-interstitial diseases),31,Renal,Morbidity,1.0,0.027777777777777776,1,N15,N15: Other renal tubulo-interstitial diseases,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -858,N16,(renal tubulo-interstitial disorders in diseases classified elsewhere),31,Renal,Morbidity,1.0,0.027777777777777776,1,N16,N16: Renal tubulo-interstitial disorders in diseases,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -859,N17,(acute renal failure),31,Renal,Morbidity,1.0,0.027777777777777776,1,N17,N17: Acute renal failure,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -860,N18,(chronic renal failure),31,Renal,Morbidity,1.0,0.027777777777777776,1,N18,N18: Chronic kidney disease,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -861,N19,(unspecified renal failure),31,Renal,Morbidity,1.0,0.027777777777777776,1,N19,N19: Unspecified kidney failure,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -862,N20,(calculus of kidney and ureter),31,Renal,Morbidity,1.0,0.027777777777777776,4,N20.0;N20.1;N20.2;N20.9,"N20.0: Calculus of kidney | N20.1: Calculus of ureter | N20.2: Calculus of kidney with calculus of ureter | N20.9: Urinary calculus, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -866,N25,(disorders resulting from impaired renal tubular function),31,Renal,Morbidity,1.0,0.027777777777777776,1,N25,N25: Disorders resulting from impaired renal tubular function,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -867,N26,(unspecified contracted kidney),31,Renal,Morbidity,1.0,0.027777777777777776,1,N26,N26: Unspecified contracted kidney,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -869,N28,"(other disorders of kidney and ureter, not elsewhere classified)",31,Renal,Morbidity,1.0,0.027777777777777776,4,N28.0;N28.80;N28.88;N28.9,"N28.0: Ischaemia and infarction of kidney | N28.80: Hypertrophy of kidney | N28.88: Other specified disorders of kidney and ureter | N28.9: Disorder of kidney and ureter, unspecified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -870,N29,(other disorders of kidney and ureter in diseases classified elsewhere),31,Renal,Morbidity,1.0,0.027777777777777776,1,N29,N29: Other disorders of kidney and ureter in diseases,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -879,N39,(other disorders of urinary system),19,Incontinence,Morbidity,1.0,0.027777777777777776,2,N39.30;N39.4,N39.30: Mixed incontinence | N39.4: Other specified urinary incontinence,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -879,N39,(other disorders of urinary system),20,Infections,Other,1.0,0.027777777777777776,1,N39.0,"N39.0: Urinary tract infection, site not specified",hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -888,N48,(other disorders of penis),30,Pain,Other,1.0,0.027777777777777776,1,N48.8,N48.8: Other specified disorders of penis,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -890,N50,(other disorders of male genital organs),30,Pain,Other,1.0,0.027777777777777776,1,N50.8,N50.8: Other specified disorders of male genital organs,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -896,N64,(other disorders of breast),30,Pain,Other,1.0,0.027777777777777776,1,N64.4,N64.4: Mastodynia,hfrm_child_of_label,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1133,C00,Malignant neoplasm of lip,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C00,C00: Malignant neoplasm of lip,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1134,C01,Malignant neoplasm of base of tongue,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C01,C01: Malignant neoplasm of base of tongue,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1135,C02,Malignant neoplasm of other and unspecified parts of tongue,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C02,C02: Malignant neoplasm of other and unspecified parts of tongue,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1136,C03,Malignant neoplasm of gum,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C03,C03: Malignant neoplasm of gum,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1137,C04,Malignant neoplasm of floor of mouth,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C04,C04: Malignant neoplasm of floor of mouth,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1138,C05,Malignant neoplasm of palate,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C05,C05: Malignant neoplasm of palate,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1139,C06,Malignant neoplasm of other and unspecified parts of mouth,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C06,C06: Malignant neoplasm of other and unspecified parts of mouth,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1140,C07,Malignant neoplasm of parotid gland,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C07,C07: Malignant neoplasm of parotid gland,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1141,C08,Malignant neoplasm of other and unspecified major salivary glands,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C08,C08: Malignant neoplasm of other and unspecified major,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1142,C09,Malignant neoplasm of tonsil,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C09,C09: Malignant neoplasm of tonsil,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1143,C10,Malignant neoplasm of oropharynx,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C10,C10: Malignant neoplasm of oropharynx,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1144,C11,Malignant neoplasm of nasopharynx,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C11,C11: Malignant neoplasm of nasopharynx,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1145,C12,Malignant neoplasm of pyriform sinus,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C12,C12: Malignant neoplasm of pyriform sinus,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1146,C13,Malignant neoplasm of hypopharynx,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C13,C13: Malignant neoplasm of hypopharynx,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1147,C14,"Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx",3,Cancer,Morbidity,1.0,0.027777777777777776,1,C14,"C14: Malignant neoplasm of other and ill-defined sites in the lip,",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1148,C15,Malignant neoplasm of oesophagus,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C15,C15: Malignant neoplasm of oesophagus,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1149,C16,Malignant neoplasm of stomach,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C16,C16: Malignant neoplasm of stomach,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1150,C17,Malignant neoplasm of small intestine,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C17,C17: Malignant neoplasm of small intestine,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1151,C18,Malignant neoplasm of colon,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C18,C18: Malignant neoplasm of colon,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1152,C19,Malignant neoplasm of rectosigmoid junction,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C19,C19: Malignant neoplasm of rectosigmoid junction,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1153,C20,Malignant neoplasm of rectum,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C20,C20: Malignant neoplasm of rectum,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1154,C21,Malignant neoplasm of anus and anal canal,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C21,C21: Malignant neoplasm of anus and anal canal,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1155,C22,Malignant neoplasm of liver and intrahepatic bile ducts,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C22,C22: Malignant neoplasm of liver and intrahepatic bile ducts,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1156,C23,Malignant neoplasm of gallbladder,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C23,C23: Malignant neoplasm of gallbladder,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1157,C24,Malignant neoplasm of other and unspecified parts of biliary tract,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C24,C24: Malignant neoplasm of other and unspecified parts,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1158,C25,Malignant neoplasm of pancreas,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C25,C25: Malignant neoplasm of pancreas,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1159,C26,Malignant neoplasm of other and ill-defined digestive organs,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C26,C26: Malignant neoplasm of other and ill-defined digestive organs,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1160,C30,Malignant neoplasm of nasal cavity and middle ear,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C30,C30: Malignant neoplasm of nasal cavity and middle ear,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1161,C31,Malignant neoplasm of accessory sinuses,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C31,C31: Malignant neoplasm of accessory sinuses,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1162,C32,Malignant neoplasm of larynx,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C32,C32: Malignant neoplasm of larynx,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1163,C33,Malignant neoplasm of trachea,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C33,C33: Malignant neoplasm of trachea,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1164,C34,Malignant neoplasm of bronchus and lung,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C34,C34: Malignant neoplasm of bronchus and lung,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1165,C37,Malignant neoplasm of thymus,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C37,C37: Malignant neoplasm of thymus,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1166,C38,"Malignant neoplasm of heart, mediastinum and pleura",3,Cancer,Morbidity,1.0,0.027777777777777776,1,C38,"C38: Malignant neoplasm of heart, mediastinum and pleura",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1167,C39,Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C39,C39: Malignant neoplasm of other and ill-defined sites in the,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1168,C40,Malignant neoplasm of bone and articular cartilage of limbs,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C40,C40: Malignant neoplasm of bone and articular cartilage of limbs,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1169,C41,Malignant neoplasm of bone and articular cartilage of other and unspecified sites,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C41,C41: Malignant neoplasm of bone and articular cartilage of other,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1171,C43,Malignant melanoma of skin,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C43,C43: Malignant melanoma of skin,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1172,C44,Other malignant neoplasms of skin,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C44,C44: Other malignant neoplasms of skin,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1173,C45,Mesothelioma,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C45,C45: Mesothelioma,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1174,C46,Kaposi's sarcoma,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C46,C46: Kaposi’s sarcoma,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1175,C47,Malignant neoplasm of peripheral nerves and autonomic nervous system,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C47,C47: Malignant neoplasm of peripheral nerves and autonomic,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1176,C48,Malignant neoplasm of retroperitoneum and peritoneum,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C48,C48: Malignant neoplasm of retroperitoneum and peritoneum,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1177,C49,Malignant neoplasm of other connective and soft tissue,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C49,C49: Malignant neoplasm of other connective and soft tissue,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1178,C50,Malignant neoplasm of breast,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C50,C50: Malignant neoplasm of breast,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1179,C51,Malignant neoplasm of vulva,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C51,C51: Malignant neoplasm of vulva,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1180,C52,Malignant neoplasm of vagina,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C52,C52: Malignant neoplasm of vagina,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1181,C53,Malignant neoplasm of cervix uteri,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C53,C53: Malignant neoplasm of cervix uteri,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1182,C54,Malignant neoplasm of corpus uteri,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C54,C54: Malignant neoplasm of corpus uteri,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1183,C55,"Malignant neoplasm of uterus, part unspecified",3,Cancer,Morbidity,1.0,0.027777777777777776,1,C55,"C55: Malignant neoplasm of uterus, part unspecified",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1184,C56,Malignant neoplasm of ovary,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C56,C56: Malignant neoplasm of ovary,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1185,C57,Malignant neoplasm of other and unspecified female genital organs,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C57,C57: Malignant neoplasm of other and unspecified female,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1186,C58,Malignant neoplasm of placenta,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C58,C58: Malignant neoplasm of placenta,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1187,C60,Malignant neoplasm of penis,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C60,C60: Malignant neoplasm of penis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1188,C61,Malignant neoplasm of prostate,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C61,C61: Malignant neoplasm of prostate,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1189,C62,Malignant neoplasm of testis,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C62,C62: Malignant neoplasm of testis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1190,C63,Malignant neoplasm of other and unspecified male genital organs,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C63,C63: Malignant neoplasm of other and unspecified male,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1191,C64,"Malignant neoplasm of kidney, except renal pelvis",3,Cancer,Morbidity,1.0,0.027777777777777776,1,C64,"C64: Malignant neoplasm of kidney, except renal pelvis",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1192,C65,Malignant neoplasm of renal pelvis,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C65,C65: Malignant neoplasm of renal pelvis,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1193,C66,Malignant neoplasm of ureter,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C66,C66: Malignant neoplasm of ureter,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1194,C67,Malignant neoplasm of bladder,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C67,C67: Malignant neoplasm of bladder,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1195,C68,Malignant neoplasm of other and unspecified urinary organs,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C68,C68: Malignant neoplasm of other and unspecified urinary organs,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1196,C69,Malignant neoplasm of eye and adnexa,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C69,C69: Malignant neoplasm of eye and adnexa,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1197,C70,Malignant neoplasm of meninges,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C70,C70: Malignant neoplasm of meninges,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1198,C71,Malignant neoplasm of brain,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C71,C71: Malignant neoplasm of brain,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1199,C72,"Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system",3,Cancer,Morbidity,1.0,0.027777777777777776,1,C72,"C72: Malignant neoplasm of spinal cord, cranial nerves and other",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1200,C73,Malignant neoplasm of thyroid gland,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C73,C73: Malignant neoplasm of thyroid gland,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1201,C74,Malignant neoplasm of adrenal gland,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C74,C74: Malignant neoplasm of adrenal gland,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1202,C75,Malignant neoplasm of other endocrine glands and related structures,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C75,C75: Malignant neoplasm of other endocrine glands,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1203,C76,Malignant neoplasm of other and ill-defined sites,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C76,C76: Malignant neoplasm of other and ill-defined sites,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1204,C77,Secondary and unspecified malignant neoplasm of lymph nodes,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C77,C77: Secondary and unspecified malignant neoplasm,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1205,C78,Secondary malignant neoplasm of respiratory and digestive organs,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C78,C78: Secondary malignant neoplasm of respiratory,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1206,C79,Secondary malignant neoplasm of other sites,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C79,C79: Secondary malignant neoplasm of other and,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1207,C80,Malignant neoplasm without specification of site,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C80,C80: Malignant neoplasm without specification of site,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1208,C81,Hodgkin's disease,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C81,C81: Hodgkin lymphoma,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1209,C82,Follicular [nodular] non-Hodgkin's lymphoma,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C82,C82: Follicular lymphoma,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1210,C83,Diffuse non-Hodgkin's lymphoma,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C83,C83: Non-follicular lymphoma,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1211,C84,Peripheral and cutaneous T-cell lymphomas,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C84,C84: Mature T/NK-cell lymphomas,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1212,C85,Other and unspecified types of non-Hodgkin's lymphoma,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C85,C85: Other and unspecified types of non-Hodgkin lymphoma,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1213,C86,Other specified types of T/NK-cell lymphoma,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C86,C86: Other specified types of T/NK-cell lymphoma,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1214,C88,Malignant immunoproliferative diseases,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C88,C88: Malignant immunoproliferative diseases,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1215,C90,Multiple myeloma and malignant plasma cell neoplasms,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C90,C90: Multiple myeloma and malignant plasma cell neoplasms,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1216,C91,Lymphoid leukaemia,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C91,C91: Lymphoid leukaemia,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1217,C92,Myeloid leukaemia,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C92,C92: Myeloid leukaemia,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1218,C93,Monocytic leukaemia,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C93,C93: Monocytic leukaemia,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1219,C94,Other leukaemias of specified cell type,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C94,C94: Other leukaemias of specified cell type,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1220,C95,Leukaemia of unspecified cell type,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C95,C95: Leukaemia of unspecified cell type,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1221,C96,"Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue",3,Cancer,Morbidity,1.0,0.027777777777777776,1,C96,"C96: Other and unspecified malignant neoplasms of lymphoid,",exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1222,C97,Malignant neoplasms of independent (primary) multiple sites,3,Cancer,Morbidity,1.0,0.027777777777777776,1,C97,C97: Malignant neoplasms of independent (primary) multiple sites,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1246,D37,Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs,3,Cancer,Morbidity,1.0,0.027777777777777776,1,D37,D37: Neoplasm of uncertain or unknown behaviour of oral cavity,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1247,D38,Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs,3,Cancer,Morbidity,1.0,0.027777777777777776,1,D38,D38: Neoplasm of uncertain or unknown behaviour of middle ear,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1248,D39,Neoplasm of uncertain or unknown behaviour of female genital organs,3,Cancer,Morbidity,1.0,0.027777777777777776,1,D39,D39: Neoplasm of uncertain or unknown behaviour of female,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1249,D40,Neoplasm of uncertain or unknown behaviour of male genital organs,3,Cancer,Morbidity,1.0,0.027777777777777776,1,D40,D40: Neoplasm of uncertain or unknown behaviour of male,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1250,D41,Neoplasm of uncertain or unknown behaviour of urinary organs,3,Cancer,Morbidity,1.0,0.027777777777777776,1,D41,D41: Neoplasm of uncertain or unknown behaviour,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1251,D42,Neoplasm of uncertain or unknown behaviour of meninges,3,Cancer,Morbidity,1.0,0.027777777777777776,1,D42,D42: Neoplasm of uncertain or unknown behaviour of meninges,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1252,D43,Neoplasm of uncertain or unknown behaviour of brain and central nervous system,3,Cancer,Morbidity,1.0,0.027777777777777776,1,D43,D43: Neoplasm of uncertain or unknown behaviour of brain and,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1253,D44,Neoplasm of uncertain or unknown behaviour of endocrine glands,3,Cancer,Morbidity,1.0,0.027777777777777776,1,D44,D44: Neoplasm of uncertain or unknown behaviour,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1254,D45,Polycythaemia vera,3,Cancer,Morbidity,1.0,0.027777777777777776,1,D45,D45: Polycythaemia vera,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1255,D46,Myelodysplastic syndromes,3,Cancer,Morbidity,1.0,0.027777777777777776,1,D46,D46: Myelodysplastic syndromes,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1256,D47,"Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue",3,Cancer,Morbidity,1.0,0.027777777777777776,1,D47,D47: Other neoplasms of uncertain or unknown behaviour,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf -1257,D48,Neoplasm of uncertain or unknown behaviour of other and unspecified sites,3,Cancer,Morbidity,1.0,0.027777777777777776,1,D48,D48: Neoplasm of uncertain or unknown behaviour of other,exact,cihi-hospital-frailty-risk-measure-meth-notes-en.pdf diff --git a/compute_burden_index_landmarks.py b/compute_burden_index_landmarks.py deleted file mode 100644 index d26dd86..0000000 --- a/compute_burden_index_landmarks.py +++ /dev/null @@ -1,1120 +0,0 @@ -from __future__ import annotations - -import argparse -import multiprocessing as mp -import time -from concurrent.futures import ProcessPoolExecutor, as_completed -from pathlib import Path -from typing import Any, Iterable - -import numpy as np -import pandas as pd -import torch -from torch.nn.utils.rnn import pad_sequence -from torch.utils.data import DataLoader, IterableDataset, get_worker_info -from tqdm.auto import tqdm - -from burden_index import ( - _build_readout_grid, - _observed_formed_burden, - load_burden_context, -) -from evaluate_auc_v2 import ( - make_eval_indices, - parse_float_list, -) -from targets import CHECKUP_IDX, NO_EVENT_IDX, PAD_IDX - - -def _parse_landmark_ages(args: argparse.Namespace) -> np.ndarray: - explicit = parse_float_list(args.landmark_ages) - if explicit: - ages = np.asarray(explicit, dtype=np.float32) - else: - ages = np.arange( - float(args.landmark_start), - float(args.landmark_stop) + 1e-6, - float(args.landmark_step), - dtype=np.float32, - ) - if ages.size == 0: - raise ValueError("No landmark ages were provided.") - return ages - - -def _parse_horizon(value: Any) -> float: - horizon = float(value) - if horizon < 0: - raise ValueError(f"horizon must be non-negative, got {horizon}") - return horizon - - -def _format_horizon_for_filename(horizon: float) -> str: - text = f"{float(horizon):g}".replace("-", "m").replace(".", "p") - return f"h{text}" - - -def _parse_devices(args: argparse.Namespace) -> list[str | None]: - if args.devices is not None and str(args.devices).strip(): - devices = [x.strip() for x in str(args.devices).split(",") if x.strip()] - if not devices: - raise ValueError("--devices was provided but no valid devices were parsed.") - return devices - return [args.device] - - -def _build_burden_matrix_from_mapping( - mapping_csv: Path, - *, - token_col: str, - category_id_col: str, - category_col: str, - key_area_col: str, - weight_col: str, -) -> tuple[np.ndarray, np.ndarray, pd.DataFrame]: - df = pd.read_csv(mapping_csv) - required = {token_col, category_id_col, category_col, weight_col} - missing = sorted(required - set(df.columns)) - if missing: - raise ValueError(f"{mapping_csv} is missing required columns: {missing}") - - df = df.copy() - df[token_col] = pd.to_numeric(df[token_col], errors="raise").astype(int) - raw_category = df[category_id_col] - numeric_category = pd.to_numeric(raw_category, errors="coerce") - if numeric_category.notna().all(): - df["_burden_category_key"] = numeric_category.astype(int) - else: - df["_burden_category_key"] = raw_category.astype(str) - df[weight_col] = pd.to_numeric(df[weight_col], errors="raise").astype(float) - df = df[df[weight_col] != 0].copy() - if df.empty: - raise ValueError(f"{mapping_csv} has no non-zero burden weights.") - - disease_ids = np.asarray(sorted(df[token_col].unique().tolist()), dtype=np.int64) - category_keys = sorted(df["_burden_category_key"].unique().tolist()) - - disease_pos = {int(token): j for j, token in enumerate(disease_ids.tolist())} - category_pos = {cat: i for i, cat in enumerate(category_keys)} - A = np.zeros((len(category_keys), disease_ids.size), dtype=np.float64) - for _, row in df.iterrows(): - token = int(row[token_col]) - cat = row["_burden_category_key"] - weight = float(row[weight_col]) - A[category_pos[cat], disease_pos[token]] += weight - - meta_cols = list(dict.fromkeys(["_burden_category_key", category_id_col, category_col])) - if key_area_col in df.columns: - meta_cols.append(key_area_col) - category_meta = ( - df[meta_cols] - .drop_duplicates(subset=["_burden_category_key"]) - .sort_values("_burden_category_key") - .reset_index(drop=True) - ) - category_meta = category_meta.rename( - columns={ - "_burden_category_key": "burden_dimension_id", - category_col: "burden_dimension", - key_area_col: "burden_key_area", - } - ) - if category_id_col in category_meta.columns: - category_meta = category_meta.drop(columns=[category_id_col]) - if "burden_key_area" not in category_meta.columns: - category_meta["burden_key_area"] = "" - - return A, disease_ids, category_meta - - -def _parse_burden_types(value: str) -> list[str]: - out = [x.strip().lower() for x in str(value).split(",") if x.strip()] - if not out: - raise ValueError("burden_types must contain at least one value.") - valid = {"functional", "organ"} - unknown = sorted(set(out) - valid) - if unknown: - raise ValueError(f"Unknown burden_types {unknown}; valid values are {sorted(valid)}") - return list(dict.fromkeys(out)) - - -def _load_mapping_specs(args: argparse.Namespace) -> list[dict[str, Any]]: - specs: list[dict[str, Any]] = [] - for burden_type in _parse_burden_types(args.burden_types): - if burden_type == "functional": - path = Path(args.functional_mapping_csv) - specs.append( - { - "burden_type": "functional", - "mapping_csv": path, - "token_col": "token_id", - "category_id_col": "hfrm_category_id", - "category_col": "hfrm_category", - "key_area_col": "hfrm_key_area", - "weight_col": args.functional_weight_col, - } - ) - elif burden_type == "organ": - path = Path(args.organ_mapping_csv) - specs.append( - { - "burden_type": "organ", - "mapping_csv": path, - "token_col": "token_id", - "category_id_col": "organ_system", - "category_col": "organ_system", - "key_area_col": "icd10_chapter_name", - "weight_col": "organ_weight", - } - ) - for spec in specs: - if not spec["mapping_csv"].exists(): - raise FileNotFoundError( - f"{spec['burden_type']} mapping_csv not found: {spec['mapping_csv']}" - ) - return specs - - -def _eligible_landmark_rows( - dataset: Any, - subset_indices: np.ndarray, - landmark_ages: np.ndarray, - *, - min_history_events: int, -) -> list[dict[str, Any]]: - rows: list[dict[str, Any]] = [] - special = np.asarray([PAD_IDX, CHECKUP_IDX, NO_EVENT_IDX], dtype=np.int64) - for patient_id, dataset_index in enumerate(subset_indices.tolist()): - sample = dataset.samples[int(dataset_index)] - seq_event = np.asarray(sample["event_seq"], dtype=np.int64) - seq_time = np.asarray(sample["time_seq"], dtype=np.float32) - tgt_event = np.asarray(sample["target_event_seq"], dtype=np.int64) - tgt_time = np.asarray(sample["target_time_seq"], dtype=np.float32) - if seq_event.size == 0 or tgt_event.size == 0: - continue - - full_event = np.concatenate([seq_event, tgt_event[-1:]]) - full_time = np.concatenate([seq_time, tgt_time[-1:]]) - followup_end = float(np.max(full_time)) - - for landmark_age in landmark_ages.tolist(): - landmark_age = float(landmark_age) - if not (followup_end > landmark_age): - continue - prefix_mask = full_time <= np.float32(landmark_age) - if not np.any(prefix_mask): - continue - prefix_events = full_event[prefix_mask].astype(np.int64, copy=False) - prefix_times = full_time[prefix_mask].astype(np.float32, copy=False) - valid_history = ~np.isin(prefix_events, special) - if int(valid_history.sum()) < int(min_history_events): - continue - - rows.append( - { - "patient_id": int(patient_id), - "dataset_index": int(dataset_index), - "sex": int(sample["sex"]), - "landmark_age": np.float32(landmark_age), - "t_query": np.float32(landmark_age), - "followup_end_time": np.float32(followup_end), - "event_seq": prefix_events, - "time_seq": prefix_times, - "other_type": np.asarray(sample["other_type"], dtype=np.int64), - "other_value": np.asarray(sample["other_value"], dtype=np.float32), - "other_value_kind": np.asarray( - sample["other_value_kind"], dtype=np.int64), - "other_time": np.asarray(sample["other_time"], dtype=np.float32), - } - ) - return rows - - -def _row_to_worker_spec(row: dict[str, Any]) -> dict[str, Any]: - return { - "patient_id": int(row["patient_id"]), - "dataset_index": int(row["dataset_index"]), - "landmark_age": float(row["landmark_age"]), - "followup_end_time": float(row["followup_end_time"]), - } - - -def _materialize_worker_rows( - dataset: Any, - row_specs: list[dict[str, Any]], -) -> list[dict[str, Any]]: - rows: list[dict[str, Any]] = [] - for spec in row_specs: - sample = dataset.samples[int(spec["dataset_index"])] - seq_event = np.asarray(sample["event_seq"], dtype=np.int64) - seq_time = np.asarray(sample["time_seq"], dtype=np.float32) - tgt_event = np.asarray(sample["target_event_seq"], dtype=np.int64) - tgt_time = np.asarray(sample["target_time_seq"], dtype=np.float32) - full_event = np.concatenate([seq_event, tgt_event[-1:]]) - full_time = np.concatenate([seq_time, tgt_time[-1:]]) - t_query = np.float32(float(spec["landmark_age"])) - prefix_mask = full_time <= t_query - landmark_age = np.float32(float(spec["landmark_age"])) - if landmark_age != t_query: - raise RuntimeError( - f"landmark_age and t_query diverged for dataset_index={spec['dataset_index']}" - ) - rows.append( - { - "patient_id": int(spec["patient_id"]), - "dataset_index": int(spec["dataset_index"]), - "sex": int(sample["sex"]), - "landmark_age": landmark_age, - "t_query": t_query, - "followup_end_time": np.float32(float(spec["followup_end_time"])), - "event_seq": full_event[prefix_mask].astype(np.int64, copy=False), - "time_seq": full_time[prefix_mask].astype(np.float32, copy=False), - "other_type": np.asarray(sample["other_type"], dtype=np.int64), - "other_value": np.asarray(sample["other_value"], dtype=np.float32), - "other_value_kind": np.asarray(sample["other_value_kind"], dtype=np.int64), - "other_time": np.asarray(sample["other_time"], dtype=np.float32), - } - ) - return rows - - -def _config_split_indices( - n: int, - cfg: dict[str, Any], - eval_split: str, - subset_size: int, -) -> np.ndarray: - args = argparse.Namespace( - train_ratio=None, - val_ratio=None, - test_ratio=None, - seed=None, - eval_split=eval_split, - dataset_subset_size=subset_size if subset_size > 0 else None, - ) - # make_eval_indices reads len(dataset), so a small shim is enough. - class _Sized: - def __len__(self) -> int: - return n - - return make_eval_indices(_Sized(), args, cfg) - - -class ReadoutJobIterableDataset(IterableDataset): - def __init__( - self, - *, - rows: list[dict[str, Any]], - formed_mode: str, - horizon: float, - ) -> None: - super().__init__() - self.rows = rows - self.formed_mode = str(formed_mode) - self.horizon = float(horizon) - if self.formed_mode not in {"observed", "model_weighted"}: - raise ValueError(f"Unknown formed_mode={self.formed_mode!r}") - - def __iter__(self) -> Iterable[dict[str, torch.Tensor]]: - worker = get_worker_info() - if worker is None: - start, step = 0, 1 - else: - start, step = int(worker.id), int(worker.num_workers) - - for row_idx in range(start, len(self.rows), step): - row = self.rows[row_idx] - if self.formed_mode == "model_weighted": - grid = _build_readout_grid( - event_seq=row["event_seq"], - time_seq=row["time_seq"], - other_type=row["other_type"], - other_time=row["other_time"], - t_query=float(row["t_query"]), - ) - if grid.size > 0: - end_times = np.concatenate( - [grid[1:], np.asarray([row["t_query"]], dtype=np.float32)] - ) - row_deltas = np.maximum(end_times - grid, 0.0).astype(np.float32) - valid = row_deltas > 0 - for query_time, delta in zip(grid[valid].tolist(), row_deltas[valid].tolist()): - yield _make_readout_job(row, row_idx, "formed", query_time, delta) - if self.horizon > 0: - yield _make_readout_job( - row, - row_idx, - "future", - float(row["t_query"]), - self.horizon, - ) - - -def _make_readout_job( - row: dict[str, Any], - row_idx: int, - kind: str, - query_time: float, - delta: float, -) -> dict[str, torch.Tensor]: - return { - "event_seq": torch.from_numpy(np.asarray(row["event_seq"], dtype=np.int64)).long(), - "time_seq": torch.from_numpy(np.asarray(row["time_seq"], dtype=np.float32)).float(), - "sex": torch.tensor(int(row["sex"]), dtype=torch.long), - "other_type": torch.from_numpy(np.asarray(row["other_type"], dtype=np.int64)).long(), - "other_value": torch.from_numpy(np.asarray(row["other_value"], dtype=np.float32)).float(), - "other_value_kind": torch.from_numpy( - np.asarray(row["other_value_kind"], dtype=np.int64) - ).long(), - "other_time": torch.from_numpy(np.asarray(row["other_time"], dtype=np.float32)).float(), - "query_time": torch.tensor(float(query_time), dtype=torch.float32), - "delta": torch.tensor(float(delta), dtype=torch.float32), - "row_idx": torch.tensor(int(row_idx), dtype=torch.long), - "kind": torch.tensor(0 if kind == "formed" else 1, dtype=torch.long), - } - - -def _collate_readout_jobs(batch: list[dict[str, torch.Tensor]]) -> dict[str, torch.Tensor]: - event_seq = pad_sequence( - [x["event_seq"] for x in batch], batch_first=True, padding_value=PAD_IDX - ) - time_seq = pad_sequence( - [x["time_seq"] for x in batch], batch_first=True, padding_value=0.0 - ) - other_type = pad_sequence( - [x["other_type"] for x in batch], batch_first=True, padding_value=0 - ) - other_value = pad_sequence( - [x["other_value"] for x in batch], batch_first=True, padding_value=0.0 - ) - other_value_kind = pad_sequence( - [x["other_value_kind"] for x in batch], batch_first=True, padding_value=0 - ) - other_time = pad_sequence( - [x["other_time"] for x in batch], batch_first=True, padding_value=0.0 - ) - return { - "event_seq": event_seq, - "time_seq": time_seq, - "padding_mask": event_seq > PAD_IDX, - "sex": torch.stack([x["sex"] for x in batch]), - "other_type": other_type, - "other_value": other_value, - "other_value_kind": other_value_kind, - "other_time": other_time, - "query_time": torch.stack([x["query_time"] for x in batch]), - "delta": torch.stack([x["delta"] for x in batch]), - "row_idx": torch.stack([x["row_idx"] for x in batch]), - "kind": torch.stack([x["kind"] for x in batch]), - } - - -@torch.inference_mode() -def _query_hidden_readout_batch( - *, - ctx: Any, - batch: dict[str, torch.Tensor], -) -> torch.Tensor: - event = batch["event_seq"].long().to(ctx.device, non_blocking=True) - return ctx.model( - event_seq=event, - time_seq=batch["time_seq"].float().to(ctx.device, non_blocking=True), - sex=batch["sex"].long().to(ctx.device, non_blocking=True), - padding_mask=event > PAD_IDX, - t_query=batch["query_time"].float().to(ctx.device, non_blocking=True), - other_type=batch["other_type"].long().to(ctx.device, non_blocking=True), - other_value=batch["other_value"].float().to(ctx.device, non_blocking=True), - other_value_kind=batch["other_value_kind"].long().to(ctx.device, non_blocking=True), - other_time=batch["other_time"].float().to(ctx.device, non_blocking=True), - target_mode="all_future", - ) - -@torch.inference_mode() -def _probabilities_from_hidden_torch( - *, - ctx: Any, - hidden: torch.Tensor, - disease_ids: np.ndarray, - deltas: np.ndarray, -) -> torch.Tensor: - if hidden.ndim != 2: - raise ValueError(f"hidden must have shape (N, H), got {tuple(hidden.shape)}") - if deltas.ndim != 1 or deltas.size != hidden.shape[0]: - raise ValueError( - "deltas must be 1D with the same length as hidden rows, got " - f"{deltas.shape} vs {tuple(hidden.shape)}" - ) - - ids = torch.as_tensor(disease_ids, dtype=torch.long, device=ctx.device) - logits = ctx.model.calc_risk(hidden)[:, ids] - rate = torch.nn.functional.softplus(logits).clamp_min(1e-8) - delta_t = torch.as_tensor(deltas, dtype=rate.dtype, device=ctx.device).clamp_min(0) - - if ctx.dist_mode == "weibull": - rho = ctx.model.calc_weibull_rho(hidden)[:, ids] - exposure = torch.pow(delta_t[:, None], rho) - elif ctx.dist_mode == "mixed": - exposure = delta_t[:, None].expand_as(rate) - death_idx = int(getattr(ctx.model, "death_idx", getattr(ctx.model, "vocab_size", 0) - 1)) - death_cols = [j for j, token in enumerate(disease_ids.tolist()) if int(token) == death_idx] - if death_cols: - death_rho = ctx.model.calc_death_rho(hidden) - for col in death_cols: - exposure[:, int(col)] = torch.pow(delta_t, death_rho) - else: - exposure = delta_t[:, None].expand_as(rate) - - return -torch.expm1(-rate * exposure) - -@torch.inference_mode() -def _readout_probabilities_from_batch( - *, - ctx: Any, - batch: dict[str, torch.Tensor], - union_disease_ids: np.ndarray, -) -> torch.Tensor: - hidden = _query_hidden_readout_batch(ctx=ctx, batch=batch) - deltas = batch["delta"].detach().cpu().numpy().astype(np.float32, copy=False) - return _probabilities_from_hidden_torch( - ctx=ctx, - hidden=hidden, - disease_ids=union_disease_ids, - deltas=deltas, - ).to(dtype=torch.float32) - - -def _observed_formed_for_rows( - *, - rows: list[dict[str, Any]], - union_disease_ids: np.ndarray, -) -> np.ndarray: - formed = np.zeros((len(rows), union_disease_ids.size), dtype=np.float64) - for row_idx, row in enumerate(rows): - formed[row_idx] = _observed_formed_burden( - disease_ids=union_disease_ids, - event_seq=row["event_seq"], - time_seq=row["time_seq"], - t_query=float(row["t_query"]), - ) - return formed - - -def _apply_readout_batch_to_accumulators( - *, - batch: dict[str, torch.Tensor], - readout_prob: torch.Tensor, - survival_by_row: torch.Tensor | None, - future_prob_by_row: torch.Tensor, - ctx: Any, -) -> None: - if readout_prob.numel() == 0: - return - - row_indices = batch["row_idx"].long().to(ctx.device, non_blocking=True) - kinds = batch["kind"].long().to(ctx.device, non_blocking=True) - kind_is_formed = kinds == 0 - kind_is_future = kinds == 1 - - if survival_by_row is not None and bool(kind_is_formed.any().item()): - formed_rows = row_indices[kind_is_formed] - formed_survival = 1.0 - readout_prob[kind_is_formed].clamp(0.0, 1.0) - if hasattr(survival_by_row, "scatter_reduce_"): - survival_by_row.scatter_reduce_( - dim=0, - index=formed_rows[:, None].expand_as(formed_survival), - src=formed_survival, - reduce="prod", - include_self=True, - ) - else: - for job_idx in torch.nonzero(kind_is_formed, as_tuple=False).flatten().tolist(): - survival_by_row[int(row_indices[job_idx].item())] *= ( - 1.0 - readout_prob[job_idx].clamp(0.0, 1.0) - ) - if bool(kind_is_future.any().item()): - future_rows = row_indices[kind_is_future] - future_prob_by_row[future_rows] = readout_prob[kind_is_future] - - -def _project_bi_rows( - *, - rows: list[dict[str, Any]], - horizon: float, - matrices: list[dict[str, Any]], - formed_mode: str, - formed_by_row: torch.Tensor, - future_prob_by_row: torch.Tensor, - ctx: Any, -) -> list[dict[str, Any]]: - disease_future_by_row = (1.0 - formed_by_row) * future_prob_by_row - disease_total_by_row = formed_by_row + disease_future_by_row - projected: list[dict[str, Any]] = [] - for matrix in matrices: - A = torch.as_tensor(matrix["A_union"], dtype=formed_by_row.dtype, device=ctx.device) - projected.append( - { - "matrix": matrix, - "historical": torch.matmul(formed_by_row, A.T).detach().cpu().numpy(), - "future": torch.matmul(disease_future_by_row, A.T).detach().cpu().numpy(), - "total": torch.matmul(disease_total_by_row, A.T).detach().cpu().numpy(), - } - ) - - out: list[dict[str, Any]] = [] - for row_idx, row in enumerate(rows): - query_time = float(row["t_query"]) - for item in projected: - matrix = item["matrix"] - historical = item["historical"][row_idx] - future = item["future"][row_idx] - total = item["total"][row_idx] - for dim_idx, meta in matrix["category_meta"].iterrows(): - out.append( - { - "patient_id": row["patient_id"], - "dataset_index": row["dataset_index"], - "sex": row["sex"], - "landmark_age": query_time, - "t_query": query_time, - "followup_end_time": float(row["followup_end_time"]), - "horizon": float(horizon), - "formed_mode": formed_mode, - "burden_type": matrix["burden_type"], - "burden_dimension_id": meta["burden_dimension_id"], - "burden_dimension": str(meta["burden_dimension"]), - "burden_key_area": str(meta.get("burden_key_area", "")), - "bi_historical": float(historical[int(dim_idx)]), - "bi_future": float(future[int(dim_idx)]), - "bi_total": float(total[int(dim_idx)]), - } - ) - return out - - -def _write_rows_csv(rows: list[dict[str, Any]], output_path: Path) -> int: - df = pd.DataFrame(rows) - df.to_csv(output_path, index=False) - return int(len(df)) - - -def _concat_csv_shards(shard_paths: list[Path], output_path: Path) -> None: - wrote_header = False - with output_path.open("w", encoding="utf-8", newline="") as out_f: - for shard_path in shard_paths: - with shard_path.open("r", encoding="utf-8", newline="") as in_f: - header = in_f.readline() - if not wrote_header: - out_f.write(header) - wrote_header = True - for line in in_f: - out_f.write(line) - shard_path.unlink(missing_ok=True) - - -def _compute_bi_from_streamed_readouts( - *, - rows: list[dict[str, Any]], - horizon: float, - matrices: list[dict[str, Any]], - union_disease_ids: np.ndarray, - formed_mode: str, - readout_batch_size: int, - num_workers: int, - ctx: Any, - log_prefix: str | None = None, -) -> tuple[list[dict[str, Any]], int, dict[str, float]]: - horizon = float(horizon) - if horizon < 0: - raise ValueError(f"horizon must be non-negative, got {horizon}") - - dtype = torch.float32 - if formed_mode == "observed": - formed_by_row = torch.as_tensor( - _observed_formed_for_rows( - rows=rows, - union_disease_ids=union_disease_ids, - ), - dtype=dtype, - device=ctx.device, - ) - survival_by_row = None - elif formed_mode == "model_weighted": - survival_by_row = torch.ones( - (len(rows), union_disease_ids.size), - dtype=dtype, - device=ctx.device, - ) - formed_by_row = None - else: - raise ValueError(f"Unknown formed_mode={formed_mode!r}") - future_prob_by_row = torch.zeros( - (len(rows), union_disease_ids.size), - dtype=dtype, - device=ctx.device, - ) - - readout_jobs = 0 - n_batches = 0 - build_readout_sec = 0.0 - forward_sec = 0.0 - reduce_sec = 0.0 - t_loader0 = time.perf_counter() - readout_dataset = ReadoutJobIterableDataset( - rows=rows, - formed_mode=formed_mode, - horizon=horizon, - ) - readout_loader = DataLoader( - readout_dataset, - batch_size=max(1, int(readout_batch_size)), - collate_fn=_collate_readout_jobs, - num_workers=max(0, int(num_workers)), - pin_memory=ctx.device.type == "cuda", - persistent_workers=int(num_workers) > 0, - prefetch_factor=2 if int(num_workers) > 0 else None, - ) - build_readout_sec += time.perf_counter() - t_loader0 - - for batch in readout_loader: - t_forward0 = time.perf_counter() - readout_prob = _readout_probabilities_from_batch( - ctx=ctx, - batch=batch, - union_disease_ids=union_disease_ids, - ) - if ctx.device.type == "cuda": - torch.cuda.synchronize(ctx.device) - forward_sec += time.perf_counter() - t_forward0 - - t_reduce0 = time.perf_counter() - _apply_readout_batch_to_accumulators( - batch=batch, - readout_prob=readout_prob, - survival_by_row=survival_by_row, - future_prob_by_row=future_prob_by_row, - ctx=ctx, - ) - if ctx.device.type == "cuda": - torch.cuda.synchronize(ctx.device) - reduce_sec += time.perf_counter() - t_reduce0 - - n_batches += 1 - readout_jobs += int(batch["row_idx"].numel()) - if log_prefix and (n_batches == 1 or n_batches % 50 == 0): - print( - f"{log_prefix} processed {readout_jobs} readout jobs " - f"in {n_batches} batches", - flush=True, - ) - - if survival_by_row is not None: - formed_by_row = 1.0 - survival_by_row - assert formed_by_row is not None - - t_project0 = time.perf_counter() - rows_out = _project_bi_rows( - rows=rows, - horizon=horizon, - matrices=matrices, - formed_mode=formed_mode, - formed_by_row=formed_by_row, - future_prob_by_row=future_prob_by_row, - ctx=ctx, - ) - if ctx.device.type == "cuda": - torch.cuda.synchronize(ctx.device) - reduce_sec += time.perf_counter() - t_project0 - timings = { - "build_readout_sec": build_readout_sec, - "forward_sec": forward_sec, - "reduce_sec": reduce_sec, - } - return rows_out, readout_jobs, timings - - -def _compute_chunk_worker(payload: dict[str, Any]) -> dict[str, Any]: - device = payload["device"] - run_path = Path(payload["run_path"]) - shard_path = Path(payload["shard_path"]) - print( - f"[BI worker {device}] starting with {len(payload['row_specs'])} rows", - flush=True, - ) - load_start = time.perf_counter() - ctx = load_burden_context(run_path, device=device) - print( - f"[BI worker {device}] context loaded in {time.perf_counter() - load_start:.2f}s", - flush=True, - ) - materialize_start = time.perf_counter() - rows = _materialize_worker_rows(ctx.dataset, payload["row_specs"]) - print( - f"[BI worker {device}] rows materialized in " - f"{time.perf_counter() - materialize_start:.2f}s", - flush=True, - ) - out, readout_jobs, timings = _compute_bi_from_streamed_readouts( - rows=rows, - horizon=payload["horizon"], - matrices=payload["matrices"], - union_disease_ids=payload["union_disease_ids"], - formed_mode=payload["formed_mode"], - readout_batch_size=int(payload["readout_batch_size"]), - num_workers=int(payload["num_workers"]), - ctx=ctx, - log_prefix=f"[BI worker {device}]", - ) - print( - f"[BI worker {device}] done: readout_jobs={readout_jobs}, " - f"build={timings['build_readout_sec']:.2f}s, " - f"forward={timings['forward_sec']:.2f}s, " - f"reduce={timings['reduce_sec']:.2f}s", - flush=True, - ) - write_start = time.perf_counter() - row_count = _write_rows_csv(out, shard_path) - timings["write_csv_sec"] = time.perf_counter() - write_start - print( - f"[BI worker {device}] wrote {row_count} rows to {shard_path} " - f"in {timings['write_csv_sec']:.2f}s", - flush=True, - ) - return { - "shard_path": str(shard_path), - "row_count": row_count, - "readout_jobs": readout_jobs, - "timings": timings, - } - - -def _attach_union_projection( - matrices: list[dict[str, Any]], -) -> tuple[np.ndarray, list[dict[str, Any]]]: - union_disease_ids = np.asarray( - sorted( - { - int(token) - for matrix in matrices - for token in np.asarray(matrix["disease_ids"], dtype=np.int64).tolist() - } - ), - dtype=np.int64, - ) - if union_disease_ids.size == 0: - raise ValueError("No disease tokens are covered by the requested burden matrices.") - - union_pos = {int(token): i for i, token in enumerate(union_disease_ids.tolist())} - projected: list[dict[str, Any]] = [] - for matrix in matrices: - disease_ids = np.asarray(matrix["disease_ids"], dtype=np.int64) - A = np.asarray(matrix["A"], dtype=np.float64) - A_union = np.zeros((A.shape[0], union_disease_ids.size), dtype=np.float64) - for local_col, token in enumerate(disease_ids.tolist()): - A_union[:, union_pos[int(token)]] += A[:, int(local_col)] - item = dict(matrix) - item["A_union"] = A_union - projected.append(item) - return union_disease_ids, projected - - -def _split_rows_for_devices( - rows: list[dict[str, Any]], - devices: list[str | None], - *, - formed_mode: str, - horizon: float, -) -> list[tuple[str | None, list[dict[str, Any]]]]: - if len(devices) <= 1: - return [(devices[0], rows)] - - buckets: list[list[dict[str, Any]]] = [[] for _ in devices] - loads = np.zeros(len(devices), dtype=np.int64) - weighted_rows = sorted( - rows, - key=lambda row: _estimate_readout_jobs_for_row( - row, - formed_mode=formed_mode, - horizon=horizon, - ), - reverse=True, - ) - for row in weighted_rows: - bucket_idx = int(np.argmin(loads)) - buckets[bucket_idx].append(row) - loads[bucket_idx] += _estimate_readout_jobs_for_row( - row, - formed_mode=formed_mode, - horizon=horizon, - ) - - chunks: list[tuple[str | None, list[dict[str, Any]]]] = [] - for device, bucket in zip(devices, buckets): - if not bucket: - continue - chunks.append((device, bucket)) - return chunks - - -def _estimate_readout_jobs_for_row( - row: dict[str, Any], - *, - formed_mode: str, - horizon: float, -) -> int: - n_jobs = 0 - if formed_mode == "model_weighted": - grid = _build_readout_grid( - event_seq=row["event_seq"], - time_seq=row["time_seq"], - other_type=row["other_type"], - other_time=row["other_time"], - t_query=float(row["t_query"]), - ) - if grid.size > 0: - end_times = np.concatenate([grid[1:], np.asarray([row["t_query"]], dtype=np.float32)]) - n_jobs += int(np.sum(np.maximum(end_times - grid, 0.0) > 0)) - if horizon > 0: - n_jobs += 1 - return max(n_jobs, 1) - - -def main() -> None: - parser = argparse.ArgumentParser( - description="Compute DeepHealth Burden Indices at landmark ages." - ) - parser.add_argument("--run_path", type=str, required=True) - parser.add_argument("--burden_types", type=str, default="functional,organ", - help="Comma-separated burden types to compute: functional,organ.") - parser.add_argument("--functional_mapping_csv", type=str, - default="cihi_hfrm_label_mapping.csv") - parser.add_argument("--organ_mapping_csv", type=str, - default="icd10_organ_label_mapping.csv") - parser.add_argument("--output_path", type=str, default=None) - parser.add_argument("--eval_split", type=str, default="test", - choices=["train", "val", "valid", "validation", "test", "all"]) - parser.add_argument("--formed_mode", type=str, default="model_weighted", - choices=["observed", "model_weighted"]) - parser.add_argument( - "--horizon", - type=float, - required=True, - help=( - "Future horizon in years. Use 0 to compute historical burden only " - "(bi_future=0 and bi_total=bi_historical)." - ), - ) - parser.add_argument("--landmark_ages", type=str, default=None) - parser.add_argument("--landmark_start", type=float, default=40.0) - parser.add_argument("--landmark_stop", type=float, default=80.0) - parser.add_argument("--landmark_step", type=float, default=5.0) - parser.add_argument("--min_history_events", type=int, default=1) - parser.add_argument("--dataset_subset_size", type=int, default=0) - parser.add_argument( - "--readout_batch_size", - type=int, - default=8192, - help=( - "Number of readout points forwarded together inside each worker. " - "Increase this to improve GPU utilization if memory allows." - ), - ) - parser.add_argument( - "--num_workers", - type=int, - default=4, - help="DataLoader workers per GPU process for readout job generation.", - ) - parser.add_argument("--device", type=str, default=None) - parser.add_argument( - "--devices", - type=str, - default=None, - help=( - "Comma-separated devices for data-parallel BI computation, e.g. " - "'cuda:0,cuda:1'. Overrides --device when provided." - ), - ) - parser.add_argument( - "--mp_start_method", - type=str, - default="fork", - choices=["fork", "forkserver"], - help="Multiprocessing start method for Linux multi-GPU runs.", - ) - parser.add_argument("--functional_weight_col", type=str, - default="hfrm_normalized_weight") - args = parser.parse_args() - - run_path = Path(args.run_path) - mapping_specs = _load_mapping_specs(args) - devices = _parse_devices(args) - - initial_device = "cpu" if len(devices) > 1 else devices[0] - ctx = load_burden_context(run_path, device=initial_device) - matrices = [] - for spec in mapping_specs: - A, disease_ids, category_meta = _build_burden_matrix_from_mapping( - spec["mapping_csv"], - token_col=spec["token_col"], - category_id_col=spec["category_id_col"], - category_col=spec["category_col"], - key_area_col=spec["key_area_col"], - weight_col=spec["weight_col"], - ) - matrices.append( - { - "burden_type": spec["burden_type"], - "A": A, - "disease_ids": disease_ids, - "category_meta": category_meta, - } - ) - union_disease_ids, matrices = _attach_union_projection(matrices) - landmark_ages = _parse_landmark_ages(args) - horizon = _parse_horizon(args.horizon) - eval_split = str(args.eval_split).lower() - if eval_split in {"valid", "validation"}: - eval_split = "val" - subset_indices = _config_split_indices( - len(ctx.dataset), - ctx.cfg, - eval_split, - int(args.dataset_subset_size), - ) - rows = _eligible_landmark_rows( - ctx.dataset, - subset_indices, - landmark_ages, - min_history_events=int(args.min_history_events), - ) - if not rows: - raise RuntimeError( - "No eligible landmark rows. Check eval split, landmark ages, and min_history_events." - ) - - output_path = Path(args.output_path) if args.output_path else ( - run_path - / f"burden_index_{eval_split}_{args.formed_mode}_{_format_horizon_for_filename(horizon)}.csv" - ) - output_path.parent.mkdir(parents=True, exist_ok=True) - - total_readout_jobs = 0 - output_written = False - shard_paths: list[Path] = [] - total_timings = { - "build_readout_sec": 0.0, - "forward_sec": 0.0, - "reduce_sec": 0.0, - "write_csv_sec": 0.0, - } - row_chunks = _split_rows_for_devices( - rows, - devices, - formed_mode=args.formed_mode, - horizon=horizon, - ) - for device, chunk_rows in row_chunks: - estimated_jobs = sum( - _estimate_readout_jobs_for_row( - row, - formed_mode=args.formed_mode, - horizon=horizon, - ) - for row in chunk_rows - ) - print( - f"Assigned {len(chunk_rows)} rows / ~{estimated_jobs} readout jobs to {device}", - flush=True, - ) - if len(row_chunks) == 1: - all_rows, total_readout_jobs, timings = _compute_bi_from_streamed_readouts( - rows=rows, - horizon=horizon, - matrices=matrices, - union_disease_ids=union_disease_ids, - formed_mode=args.formed_mode, - readout_batch_size=int(args.readout_batch_size), - num_workers=int(args.num_workers), - ctx=ctx, - log_prefix="[BI main]", - ) - for key, value in timings.items(): - total_timings[key] += float(value) - write_start = time.perf_counter() - _write_rows_csv(all_rows, output_path) - total_timings["write_csv_sec"] = time.perf_counter() - write_start - output_written = True - else: - # The main-process context is only needed to build the dataset and rows. - # Workers load their own model copy on the assigned device. - del ctx - payloads = [ - { - "device": device, - "run_path": str(run_path), - "shard_path": str( - output_path.with_name( - f"{output_path.stem}.part{part_idx:03d}{output_path.suffix}" - ) - ), - "row_specs": [_row_to_worker_spec(row) for row in chunk_rows], - "horizon": horizon, - "matrices": matrices, - "union_disease_ids": union_disease_ids, - "readout_batch_size": int(args.readout_batch_size), - "num_workers": int(args.num_workers), - "formed_mode": args.formed_mode, - } - for part_idx, (device, chunk_rows) in enumerate(row_chunks) - ] - with ProcessPoolExecutor( - max_workers=len(payloads), - mp_context=mp.get_context(args.mp_start_method), - ) as executor: - futures = [executor.submit(_compute_chunk_worker, p) for p in payloads] - for future in tqdm( - as_completed(futures), - total=len(futures), - desc="Computing BI chunks", - dynamic_ncols=True, - ): - result = future.result() - shard_paths.append(Path(result["shard_path"])) - total_readout_jobs += int(result["readout_jobs"]) - for key, value in result["timings"].items(): - total_timings[key] += float(value) - - write_start = time.perf_counter() - _concat_csv_shards(sorted(shard_paths), output_path) - total_timings["write_csv_sec"] += time.perf_counter() - write_start - output_written = True - - if not output_written: - raise RuntimeError("BI output was not written.") - print(f"Run path: {run_path}") - print(f"Eval split: {eval_split}") - print(f"Horizon: {horizon:g}") - print(f"Landmark rows: {len(rows)}") - print(f"Readout jobs: {total_readout_jobs}") - print(f"Readout batch size per worker: {int(args.readout_batch_size)}") - print(f"DataLoader workers per GPU process: {int(args.num_workers)}") - print(f"Multiprocessing start method: {args.mp_start_method}") - print( - "Timing seconds: " - f"build_readout={total_timings['build_readout_sec']:.2f}, " - f"forward={total_timings['forward_sec']:.2f}, " - f"reduce={total_timings['reduce_sec']:.2f}, " - f"write_csv={total_timings['write_csv_sec']:.2f}" - ) - print(f"Devices: {', '.join(str(d) for d, _ in row_chunks)}") - for matrix in matrices: - print( - f"{matrix['burden_type']} dimensions: {matrix['A'].shape[0]}, " - f"mapped disease tokens: {matrix['A'].shape[1]}" - ) - print(f"Union disease tokens evaluated once per sample: {union_disease_ids.size}") - print(f"Output: {output_path}") - - -if __name__ == "__main__": - main() diff --git a/compute_deephealth_indices_landmarks.py b/compute_deephealth_indices_landmarks.py new file mode 100644 index 0000000..d5657d7 --- /dev/null +++ b/compute_deephealth_indices_landmarks.py @@ -0,0 +1,717 @@ +from __future__ import annotations + +import argparse +import multiprocessing as mp +import time +from concurrent.futures import ProcessPoolExecutor, as_completed +from pathlib import Path +from typing import Any, Iterable + +import numpy as np +import pandas as pd +import torch +from torch.nn.utils.rnn import pad_sequence +from torch.utils.data import DataLoader, IterableDataset, get_worker_info +from tqdm.auto import tqdm + +from burden_index import ( + build_readout_grid, + load_deephealth_context, + probabilities_from_hidden, +) +from evaluate_auc_v2 import make_eval_indices, parse_float_list +from targets import CHECKUP_IDX, NO_EVENT_IDX, PAD_IDX + + +def _parse_landmark_ages(args: argparse.Namespace) -> np.ndarray: + explicit = parse_float_list(args.landmark_ages) + if explicit: + ages = np.asarray(explicit, dtype=np.float32) + else: + ages = np.arange( + float(args.landmark_start), + float(args.landmark_stop) + 1e-6, + float(args.landmark_step), + dtype=np.float32, + ) + if ages.size == 0: + raise ValueError("No landmark ages were provided.") + return ages + + +def _parse_devices(args: argparse.Namespace) -> list[str | None]: + if args.devices is not None and str(args.devices).strip(): + devices = [x.strip() for x in str(args.devices).split(",") if x.strip()] + if not devices: + raise ValueError("--devices was provided but no devices were parsed.") + return devices + return [args.device] + + +def _load_index_matrices( + *, + organ_mapping_csv: Path, + hfrs_mapping_csv: Path, +) -> tuple[np.ndarray, list[dict[str, Any]], dict[str, Any]]: + organ_df = pd.read_csv(organ_mapping_csv) + organ_required = {"token_id", "organ_id", "organ_label", "organ_weight"} + missing = sorted(organ_required - set(organ_df.columns)) + if missing: + raise ValueError(f"{organ_mapping_csv} is missing required columns: {missing}") + organ_df = organ_df.copy() + organ_df["token_id"] = pd.to_numeric(organ_df["token_id"], errors="raise").astype(int) + organ_df["organ_weight"] = pd.to_numeric( + organ_df["organ_weight"], errors="raise" + ).astype(float) + organ_df = organ_df[(organ_df["organ_id"].astype(str) != "") & (organ_df["organ_weight"] > 0)] + if organ_df.empty: + raise ValueError(f"{organ_mapping_csv} has no mapped organ rows.") + + hfrs_df = pd.read_csv(hfrs_mapping_csv) + hfrs_required = {"token_id", "hfrs_weight"} + missing = sorted(hfrs_required - set(hfrs_df.columns)) + if missing: + raise ValueError(f"{hfrs_mapping_csv} is missing required columns: {missing}") + hfrs_df = hfrs_df.copy() + hfrs_df["token_id"] = pd.to_numeric(hfrs_df["token_id"], errors="raise").astype(int) + hfrs_df["hfrs_weight"] = pd.to_numeric( + hfrs_df["hfrs_weight"], errors="raise" + ).astype(float) + hfrs_df = hfrs_df[hfrs_df["hfrs_weight"] > 0] + if hfrs_df.empty: + raise ValueError(f"{hfrs_mapping_csv} has no non-zero HFRS weights.") + + union_disease_ids = np.asarray( + sorted( + set(organ_df["token_id"].astype(int).tolist()) + | set(hfrs_df["token_id"].astype(int).tolist()) + ), + dtype=np.int64, + ) + union_pos = {int(token): i for i, token in enumerate(union_disease_ids.tolist())} + + organ_ids = sorted(organ_df["organ_id"].astype(str).unique().tolist()) + organ_pos = {organ_id: i for i, organ_id in enumerate(organ_ids)} + organ_matrix = np.zeros((len(organ_ids), union_disease_ids.size), dtype=np.float32) + organ_meta_by_id = {} + for _, row in organ_df.iterrows(): + organ_id = str(row["organ_id"]) + token = int(row["token_id"]) + organ_matrix[organ_pos[organ_id], union_pos[token]] = 1.0 + organ_meta_by_id.setdefault( + organ_id, + { + "index_type": "organ_involvement", + "index_id": organ_id, + "index_label": str(row["organ_label"]), + }, + ) + organ_meta = [organ_meta_by_id[organ_id] for organ_id in organ_ids] + + hfrs_weights = np.zeros(union_disease_ids.size, dtype=np.float32) + for _, row in hfrs_df.iterrows(): + hfrs_weights[union_pos[int(row["token_id"])]] = float(row["hfrs_weight"]) + hfrs_meta = { + "index_type": "frailty_risk", + "index_id": "deephealth_hfrs", + "index_label": "DeepHealth-HFRS frailty risk index", + } + + matrices = [ + { + "kind": "organ_involvement", + "matrix": organ_matrix, + "meta": organ_meta, + }, + { + "kind": "frailty_risk", + "weights": hfrs_weights, + "meta": hfrs_meta, + }, + ] + return union_disease_ids, matrices, { + "organ_mapped_tokens": int(organ_df["token_id"].nunique()), + "hfrs_mapped_tokens": int(hfrs_df["token_id"].nunique()), + } + + +def _config_split_indices( + n: int, + cfg: dict[str, Any], + eval_split: str, + subset_size: int, +) -> np.ndarray: + args = argparse.Namespace( + train_ratio=None, + val_ratio=None, + test_ratio=None, + seed=None, + eval_split=eval_split, + dataset_subset_size=subset_size if subset_size > 0 else None, + ) + + class _Sized: + def __len__(self) -> int: + return n + + return make_eval_indices(_Sized(), args, cfg) + + +def _eligible_landmark_rows( + dataset: Any, + subset_indices: np.ndarray, + landmark_ages: np.ndarray, + *, + min_history_events: int, +) -> list[dict[str, Any]]: + rows: list[dict[str, Any]] = [] + special = np.asarray([PAD_IDX, CHECKUP_IDX, NO_EVENT_IDX], dtype=np.int64) + for patient_id, dataset_index in enumerate(subset_indices.tolist()): + sample = dataset.samples[int(dataset_index)] + seq_event = np.asarray(sample["event_seq"], dtype=np.int64) + seq_time = np.asarray(sample["time_seq"], dtype=np.float32) + tgt_event = np.asarray(sample["target_event_seq"], dtype=np.int64) + tgt_time = np.asarray(sample["target_time_seq"], dtype=np.float32) + if seq_event.size == 0 or tgt_event.size == 0: + continue + + full_event = np.concatenate([seq_event, tgt_event[-1:]]) + full_time = np.concatenate([seq_time, tgt_time[-1:]]) + followup_end = float(np.max(full_time)) + + for landmark_age in landmark_ages.tolist(): + t_query = np.float32(float(landmark_age)) + if not (followup_end > float(t_query)): + continue + prefix_mask = full_time <= t_query + if not np.any(prefix_mask): + continue + prefix_events = full_event[prefix_mask].astype(np.int64, copy=False) + valid_history = ~np.isin(prefix_events, special) + if int(valid_history.sum()) < int(min_history_events): + continue + rows.append( + { + "patient_id": int(patient_id), + "dataset_index": int(dataset_index), + "sex": int(sample["sex"]), + "landmark_age": t_query, + "t_query": t_query, + "followup_end_time": np.float32(followup_end), + "event_seq": prefix_events, + "time_seq": full_time[prefix_mask].astype(np.float32, copy=False), + "other_type": np.asarray(sample["other_type"], dtype=np.int64), + "other_value": np.asarray(sample["other_value"], dtype=np.float32), + "other_value_kind": np.asarray(sample["other_value_kind"], dtype=np.int64), + "other_time": np.asarray(sample["other_time"], dtype=np.float32), + } + ) + return rows + + +def _row_to_worker_spec(row: dict[str, Any]) -> dict[str, Any]: + return { + "patient_id": int(row["patient_id"]), + "dataset_index": int(row["dataset_index"]), + "landmark_age": float(row["landmark_age"]), + "followup_end_time": float(row["followup_end_time"]), + } + + +def _materialize_worker_rows( + dataset: Any, + row_specs: list[dict[str, Any]], +) -> list[dict[str, Any]]: + rows: list[dict[str, Any]] = [] + for spec in row_specs: + sample = dataset.samples[int(spec["dataset_index"])] + seq_event = np.asarray(sample["event_seq"], dtype=np.int64) + seq_time = np.asarray(sample["time_seq"], dtype=np.float32) + tgt_event = np.asarray(sample["target_event_seq"], dtype=np.int64) + tgt_time = np.asarray(sample["target_time_seq"], dtype=np.float32) + full_event = np.concatenate([seq_event, tgt_event[-1:]]) + full_time = np.concatenate([seq_time, tgt_time[-1:]]) + t_query = np.float32(float(spec["landmark_age"])) + prefix_mask = full_time <= t_query + rows.append( + { + "patient_id": int(spec["patient_id"]), + "dataset_index": int(spec["dataset_index"]), + "sex": int(sample["sex"]), + "landmark_age": t_query, + "t_query": t_query, + "followup_end_time": np.float32(float(spec["followup_end_time"])), + "event_seq": full_event[prefix_mask].astype(np.int64, copy=False), + "time_seq": full_time[prefix_mask].astype(np.float32, copy=False), + "other_type": np.asarray(sample["other_type"], dtype=np.int64), + "other_value": np.asarray(sample["other_value"], dtype=np.float32), + "other_value_kind": np.asarray(sample["other_value_kind"], dtype=np.int64), + "other_time": np.asarray(sample["other_time"], dtype=np.float32), + } + ) + return rows + + +class HistoricalReadoutDataset(IterableDataset): + def __init__(self, rows: list[dict[str, Any]]) -> None: + super().__init__() + self.rows = rows + + def __iter__(self) -> Iterable[dict[str, torch.Tensor]]: + worker = get_worker_info() + if worker is None: + start, step = 0, 1 + else: + start, step = int(worker.id), int(worker.num_workers) + + for row_idx in range(start, len(self.rows), step): + row = self.rows[row_idx] + grid = build_readout_grid( + event_seq=row["event_seq"], + time_seq=row["time_seq"], + other_type=row["other_type"], + other_time=row["other_time"], + t_query=float(row["t_query"]), + ) + if grid.size == 0: + continue + end_times = np.concatenate([grid[1:], np.asarray([row["t_query"]], dtype=np.float32)]) + deltas = np.maximum(end_times - grid, 0.0).astype(np.float32) + valid = deltas > 0 + for query_time, delta in zip(grid[valid].tolist(), deltas[valid].tolist()): + yield _make_readout_job(row, row_idx, query_time, delta) + + +def _make_readout_job( + row: dict[str, Any], + row_idx: int, + query_time: float, + delta: float, +) -> dict[str, torch.Tensor]: + return { + "event_seq": torch.from_numpy(np.asarray(row["event_seq"], dtype=np.int64)).long(), + "time_seq": torch.from_numpy(np.asarray(row["time_seq"], dtype=np.float32)).float(), + "sex": torch.tensor(int(row["sex"]), dtype=torch.long), + "other_type": torch.from_numpy(np.asarray(row["other_type"], dtype=np.int64)).long(), + "other_value": torch.from_numpy(np.asarray(row["other_value"], dtype=np.float32)).float(), + "other_value_kind": torch.from_numpy( + np.asarray(row["other_value_kind"], dtype=np.int64) + ).long(), + "other_time": torch.from_numpy(np.asarray(row["other_time"], dtype=np.float32)).float(), + "query_time": torch.tensor(float(query_time), dtype=torch.float32), + "delta": torch.tensor(float(delta), dtype=torch.float32), + "row_idx": torch.tensor(int(row_idx), dtype=torch.long), + } + + +def _collate_readout_jobs(batch: list[dict[str, torch.Tensor]]) -> dict[str, torch.Tensor]: + event_seq = pad_sequence( + [x["event_seq"] for x in batch], batch_first=True, padding_value=PAD_IDX + ) + return { + "event_seq": event_seq, + "time_seq": pad_sequence( + [x["time_seq"] for x in batch], batch_first=True, padding_value=0.0 + ), + "padding_mask": event_seq > PAD_IDX, + "sex": torch.stack([x["sex"] for x in batch]), + "other_type": pad_sequence( + [x["other_type"] for x in batch], batch_first=True, padding_value=0 + ), + "other_value": pad_sequence( + [x["other_value"] for x in batch], batch_first=True, padding_value=0.0 + ), + "other_value_kind": pad_sequence( + [x["other_value_kind"] for x in batch], batch_first=True, padding_value=0 + ), + "other_time": pad_sequence( + [x["other_time"] for x in batch], batch_first=True, padding_value=0.0 + ), + "query_time": torch.stack([x["query_time"] for x in batch]), + "delta": torch.stack([x["delta"] for x in batch]), + "row_idx": torch.stack([x["row_idx"] for x in batch]), + } + + +@torch.inference_mode() +def _readout_probabilities( + *, + ctx: Any, + batch: dict[str, torch.Tensor], + disease_ids: np.ndarray, +) -> torch.Tensor: + event = batch["event_seq"].long().to(ctx.device, non_blocking=True) + hidden = ctx.model( + event_seq=event, + time_seq=batch["time_seq"].float().to(ctx.device, non_blocking=True), + sex=batch["sex"].long().to(ctx.device, non_blocking=True), + padding_mask=event > PAD_IDX, + t_query=batch["query_time"].float().to(ctx.device, non_blocking=True), + other_type=batch["other_type"].long().to(ctx.device, non_blocking=True), + other_value=batch["other_value"].float().to(ctx.device, non_blocking=True), + other_value_kind=batch["other_value_kind"].long().to(ctx.device, non_blocking=True), + other_time=batch["other_time"].float().to(ctx.device, non_blocking=True), + target_mode="all_future", + ) + deltas = batch["delta"].detach().cpu().numpy().astype(np.float32, copy=False) + prob = probabilities_from_hidden( + ctx=ctx, + hidden=hidden, + disease_ids=disease_ids, + deltas=deltas, + ) + return torch.as_tensor(prob, dtype=torch.float32, device=ctx.device) + + +def _project_rows( + *, + rows: list[dict[str, Any]], + survival_by_row: torch.Tensor, + matrices: list[dict[str, Any]], + ctx: Any, +) -> list[dict[str, Any]]: + disease_expression = 1.0 - survival_by_row.clamp(0.0, 1.0) + disease_intensity = -torch.log(survival_by_row.clamp(1e-7, 1.0)) + out: list[dict[str, Any]] = [] + + organ_matrix = torch.as_tensor( + matrices[0]["matrix"], dtype=torch.float32, device=ctx.device + ) + organ_values = -torch.expm1(-torch.matmul(disease_intensity, organ_matrix.T)) + organ_values_np = organ_values.detach().cpu().numpy() + + hfrs_weights = torch.as_tensor( + matrices[1]["weights"], dtype=torch.float32, device=ctx.device + ) + hfrs_values = torch.matmul(disease_expression, hfrs_weights) + hfrs_values_np = hfrs_values.detach().cpu().numpy() + + for row_idx, row in enumerate(rows): + base = { + "patient_id": row["patient_id"], + "dataset_index": row["dataset_index"], + "sex": row["sex"], + "landmark_age": float(row["landmark_age"]), + "t_query": float(row["t_query"]), + "followup_end_time": float(row["followup_end_time"]), + } + for dim_idx, meta in enumerate(matrices[0]["meta"]): + out.append( + { + **base, + "index_type": meta["index_type"], + "index_id": meta["index_id"], + "index_label": meta["index_label"], + "index_value": float(organ_values_np[row_idx, dim_idx]), + } + ) + out.append( + { + **base, + "index_type": matrices[1]["meta"]["index_type"], + "index_id": matrices[1]["meta"]["index_id"], + "index_label": matrices[1]["meta"]["index_label"], + "index_value": float(hfrs_values_np[row_idx]), + } + ) + return out + + +def _compute_rows( + *, + rows: list[dict[str, Any]], + disease_ids: np.ndarray, + matrices: list[dict[str, Any]], + readout_batch_size: int, + num_workers: int, + ctx: Any, + log_prefix: str, +) -> tuple[list[dict[str, Any]], int, dict[str, float]]: + survival_by_row = torch.ones( + (len(rows), disease_ids.size), dtype=torch.float32, device=ctx.device + ) + loader = DataLoader( + HistoricalReadoutDataset(rows), + batch_size=max(1, int(readout_batch_size)), + collate_fn=_collate_readout_jobs, + num_workers=max(0, int(num_workers)), + pin_memory=ctx.device.type == "cuda", + persistent_workers=int(num_workers) > 0, + prefetch_factor=2 if int(num_workers) > 0 else None, + ) + readout_jobs = 0 + n_batches = 0 + forward_sec = 0.0 + reduce_sec = 0.0 + for batch in loader: + t0 = time.perf_counter() + prob = _readout_probabilities(ctx=ctx, batch=batch, disease_ids=disease_ids) + if ctx.device.type == "cuda": + torch.cuda.synchronize(ctx.device) + forward_sec += time.perf_counter() - t0 + + t1 = time.perf_counter() + row_indices = batch["row_idx"].long().to(ctx.device, non_blocking=True) + interval_survival = 1.0 - prob.clamp(0.0, 1.0) + if hasattr(survival_by_row, "scatter_reduce_"): + survival_by_row.scatter_reduce_( + dim=0, + index=row_indices[:, None].expand_as(interval_survival), + src=interval_survival, + reduce="prod", + include_self=True, + ) + else: + for job_idx in range(interval_survival.shape[0]): + survival_by_row[int(row_indices[job_idx].item())] *= interval_survival[job_idx] + if ctx.device.type == "cuda": + torch.cuda.synchronize(ctx.device) + reduce_sec += time.perf_counter() - t1 + + n_batches += 1 + readout_jobs += int(batch["row_idx"].numel()) + if n_batches == 1 or n_batches % 50 == 0: + print( + f"{log_prefix} processed {readout_jobs} readout jobs in {n_batches} batches", + flush=True, + ) + + t2 = time.perf_counter() + out = _project_rows( + rows=rows, + survival_by_row=survival_by_row, + matrices=matrices, + ctx=ctx, + ) + if ctx.device.type == "cuda": + torch.cuda.synchronize(ctx.device) + reduce_sec += time.perf_counter() - t2 + return out, readout_jobs, {"forward_sec": forward_sec, "reduce_sec": reduce_sec} + + +def _write_rows_csv(rows: list[dict[str, Any]], output_path: Path) -> int: + df = pd.DataFrame(rows) + df.to_csv(output_path, index=False) + return int(len(df)) + + +def _concat_csv_shards(shard_paths: list[Path], output_path: Path) -> None: + wrote_header = False + with output_path.open("w", encoding="utf-8", newline="") as out_f: + for shard_path in shard_paths: + with shard_path.open("r", encoding="utf-8", newline="") as in_f: + header = in_f.readline() + if not wrote_header: + out_f.write(header) + wrote_header = True + for line in in_f: + out_f.write(line) + shard_path.unlink(missing_ok=True) + + +def _estimate_jobs(row: dict[str, Any]) -> int: + grid = build_readout_grid( + event_seq=row["event_seq"], + time_seq=row["time_seq"], + other_type=row["other_type"], + other_time=row["other_time"], + t_query=float(row["t_query"]), + ) + if grid.size == 0: + return 1 + end_times = np.concatenate([grid[1:], np.asarray([row["t_query"]], dtype=np.float32)]) + return max(int(np.sum(np.maximum(end_times - grid, 0.0) > 0)), 1) + + +def _split_rows(rows: list[dict[str, Any]], devices: list[str | None]) -> list[tuple[str | None, list[dict[str, Any]]]]: + if len(devices) <= 1: + return [(devices[0], rows)] + buckets: list[list[dict[str, Any]]] = [[] for _ in devices] + loads = np.zeros(len(devices), dtype=np.int64) + for row in sorted(rows, key=_estimate_jobs, reverse=True): + idx = int(np.argmin(loads)) + buckets[idx].append(row) + loads[idx] += _estimate_jobs(row) + return [(device, bucket) for device, bucket in zip(devices, buckets) if bucket] + + +def _worker(payload: dict[str, Any]) -> dict[str, Any]: + device = payload["device"] + shard_path = Path(payload["shard_path"]) + print(f"[Index worker {device}] starting with {len(payload['row_specs'])} rows", flush=True) + ctx = load_deephealth_context(payload["run_path"], device=device) + rows = _materialize_worker_rows(ctx.dataset, payload["row_specs"]) + out, readout_jobs, timings = _compute_rows( + rows=rows, + disease_ids=payload["disease_ids"], + matrices=payload["matrices"], + readout_batch_size=int(payload["readout_batch_size"]), + num_workers=int(payload["num_workers"]), + ctx=ctx, + log_prefix=f"[Index worker {device}]", + ) + t0 = time.perf_counter() + row_count = _write_rows_csv(out, shard_path) + timings["write_csv_sec"] = time.perf_counter() - t0 + print(f"[Index worker {device}] wrote {row_count} rows to {shard_path}", flush=True) + return { + "shard_path": str(shard_path), + "row_count": row_count, + "readout_jobs": readout_jobs, + "timings": timings, + } + + +def main() -> None: + parser = argparse.ArgumentParser( + description="Compute DeepHealth organ involvement and frailty risk indices." + ) + parser.add_argument("--run_path", type=str, required=True) + parser.add_argument( + "--organ_mapping_csv", + type=str, + default="organ_involvement_label_mapping.csv", + ) + parser.add_argument("--hfrs_mapping_csv", type=str, default="uk_hfrs_label_mapping.csv") + parser.add_argument("--output_path", type=str, default=None) + parser.add_argument( + "--eval_split", + type=str, + default="test", + choices=["train", "val", "valid", "validation", "test", "all"], + ) + parser.add_argument("--landmark_ages", type=str, default=None) + parser.add_argument("--landmark_start", type=float, default=40.0) + parser.add_argument("--landmark_stop", type=float, default=80.0) + parser.add_argument("--landmark_step", type=float, default=5.0) + parser.add_argument("--min_history_events", type=int, default=1) + parser.add_argument("--dataset_subset_size", type=int, default=0) + parser.add_argument("--readout_batch_size", type=int, default=8192) + parser.add_argument("--num_workers", type=int, default=4) + parser.add_argument("--device", type=str, default=None) + parser.add_argument("--devices", type=str, default=None) + parser.add_argument( + "--mp_start_method", + type=str, + default="fork", + choices=["fork", "forkserver"], + ) + args = parser.parse_args() + + run_path = Path(args.run_path) + devices = _parse_devices(args) + initial_device = "cpu" if len(devices) > 1 else devices[0] + ctx = load_deephealth_context(run_path, device=initial_device) + + disease_ids, matrices, mapping_counts = _load_index_matrices( + organ_mapping_csv=Path(args.organ_mapping_csv), + hfrs_mapping_csv=Path(args.hfrs_mapping_csv), + ) + landmark_ages = _parse_landmark_ages(args) + eval_split = str(args.eval_split).lower() + if eval_split in {"valid", "validation"}: + eval_split = "val" + subset_indices = _config_split_indices( + len(ctx.dataset), + ctx.cfg, + eval_split, + int(args.dataset_subset_size), + ) + rows = _eligible_landmark_rows( + ctx.dataset, + subset_indices, + landmark_ages, + min_history_events=int(args.min_history_events), + ) + if not rows: + raise RuntimeError("No eligible landmark rows.") + + output_path = Path(args.output_path) if args.output_path else ( + run_path / f"deephealth_indices_{eval_split}.csv" + ) + output_path.parent.mkdir(parents=True, exist_ok=True) + + chunks = _split_rows(rows, devices) + for device, chunk in chunks: + print( + f"Assigned {len(chunk)} rows / ~{sum(_estimate_jobs(r) for r in chunk)} " + f"readout jobs to {device}", + flush=True, + ) + + total_readout_jobs = 0 + timings = {"forward_sec": 0.0, "reduce_sec": 0.0, "write_csv_sec": 0.0} + if len(chunks) == 1: + out, total_readout_jobs, chunk_timings = _compute_rows( + rows=rows, + disease_ids=disease_ids, + matrices=matrices, + readout_batch_size=int(args.readout_batch_size), + num_workers=int(args.num_workers), + ctx=ctx, + log_prefix="[Index main]", + ) + for key, value in chunk_timings.items(): + timings[key] += float(value) + t0 = time.perf_counter() + _write_rows_csv(out, output_path) + timings["write_csv_sec"] = time.perf_counter() - t0 + else: + del ctx + payloads = [ + { + "device": device, + "run_path": str(run_path), + "shard_path": str( + output_path.with_name( + f"{output_path.stem}.part{part_idx:03d}{output_path.suffix}" + ) + ), + "row_specs": [_row_to_worker_spec(row) for row in chunk], + "disease_ids": disease_ids, + "matrices": matrices, + "readout_batch_size": int(args.readout_batch_size), + "num_workers": int(args.num_workers), + } + for part_idx, (device, chunk) in enumerate(chunks) + ] + shard_paths = [] + with ProcessPoolExecutor( + max_workers=len(payloads), + mp_context=mp.get_context(args.mp_start_method), + ) as executor: + futures = [executor.submit(_worker, payload) for payload in payloads] + for future in tqdm( + as_completed(futures), + total=len(futures), + desc="Computing DeepHealth index chunks", + dynamic_ncols=True, + ): + result = future.result() + shard_paths.append(Path(result["shard_path"])) + total_readout_jobs += int(result["readout_jobs"]) + for key, value in result["timings"].items(): + timings[key] += float(value) + t0 = time.perf_counter() + _concat_csv_shards(sorted(shard_paths), output_path) + timings["write_csv_sec"] += time.perf_counter() - t0 + + print(f"Run path: {run_path}") + print(f"Eval split: {eval_split}") + print(f"Landmark rows: {len(rows)}") + print(f"Readout jobs: {total_readout_jobs}") + print(f"Union disease tokens: {disease_ids.size}") + print(f"Organ mapped tokens: {mapping_counts['organ_mapped_tokens']}") + print(f"HFRS mapped tokens: {mapping_counts['hfrs_mapped_tokens']}") + print( + "Timing seconds: " + f"forward={timings['forward_sec']:.2f}, " + f"reduce={timings['reduce_sec']:.2f}, " + f"write_csv={timings['write_csv_sec']:.2f}" + ) + print(f"Devices: {', '.join(str(d) for d, _ in chunks)}") + print(f"Output: {output_path}") + + +if __name__ == "__main__": + main() diff --git a/icd10_organ_label_mapping.csv b/icd10_organ_label_mapping.csv deleted file mode 100644 index e4b5811..0000000 --- a/icd10_organ_label_mapping.csv +++ /dev/null @@ -1,1257 +0,0 @@ -token_id,label_code,label_name,icd10_chapter_id,icd10_chapter_name,organ_system,organ_weight,match_source -3,A00,(cholera),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -4,A01,(typhoid and paratyphoid fevers),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -5,A02,(other salmonella infections),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -6,A03,(shigellosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -7,A04,(other bacterial intestinal infections),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -8,A05,(other bacterial foodborne intoxications),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -9,A06,(amoebiasis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -10,A07,(other protozoal intestinal diseases),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -11,A08,(viral and other specified intestinal infections),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -12,A09,(diarrhoea and gastro-enteritis of presumed infectious origin),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -13,A15,"(respiratory tuberculosis, bacteriologically and histologically confirmed)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -14,A16,"(respiratory tuberculosis, not confirmed bacteriologically or histologically)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -15,A17,(tuberculosis of nervous system),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -16,A18,(tuberculosis of other organs),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -17,A19,(miliary tuberculosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -18,A20,(plague),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -19,A22,(anthrax),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -20,A23,(brucellosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -21,A24,(glanders and melioidosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -22,A25,(rat-bite fevers),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -23,A26,(erysipeloid),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -24,A27,(leptospirosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -25,A28,"(other zoonotic bacterial diseases, not elsewhere classified)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -26,A30,(leprosy [hansen's disease]),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -27,A31,(infection due to other mycobacteria),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -28,A32,(listeriosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -29,A33,(tetanus neonatorum),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -30,A35,(other tetanus),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -31,A36,(diphtheria),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -32,A37,(whooping cough),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -33,A38,(scarlet fever),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -34,A39,(meningococcal infection),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -35,A40,(streptococcal septicaemia),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -36,A41,(other septicaemia),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -37,A42,(actinomycosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -38,A43,(nocardiosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -39,A44,(bartonellosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -40,A46,(erysipelas),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -41,A48,"(other bacterial diseases, not elsewhere classified)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -42,A49,(bacterial infection of unspecified site),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -43,A50,(congenital syphilis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -44,A51,(early syphilis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -45,A52,(late syphilis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -46,A53,(other and unspecified syphilis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -47,A54,(gonococcal infection),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -48,A55,(chlamydial lymphogranuloma (venereum)),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -49,A56,(other sexually transmitted chlamydial diseases),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -50,A58,(granuloma inguinale),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -51,A59,(trichomoniasis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -52,A60,(anogenital herpesviral [herpes simplex] infections),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -53,A63,"(other predominantly sexually transmitted diseases, not elsewhere classified)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -54,A64,(unspecified sexually transmitted disease),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -55,A66,(yaws),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -56,A67,(pinta [carate]),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -57,A68,(relapsing fevers),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -58,A69,(other spirochaetal infections),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -59,A70,(chlamydia psittaci infection),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -60,A71,(trachoma),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -61,A74,(other diseases caused by chlamydiae),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -62,A75,(typhus fever),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -63,A77,(spotted fever [tick-borne rickettsioses]),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -64,A78,(q fever),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -65,A79,(other rickettsioses),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -66,A80,(acute poliomyelitis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -67,A81,(atypical virus infections of central nervous system),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -68,A82,(rabies),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -69,A83,(mosquito-borne viral encephalitis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -70,A84,(tick-borne viral encephalitis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -71,A85,"(other viral encephalitis, not elsewhere classified)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -72,A86,(unspecified viral encephalitis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -73,A87,(viral meningitis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -74,A88,"(other viral infections of central nervous system, not elsewhere classified)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -75,A89,(unspecified viral infection of central nervous system),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -76,A90,(dengue fever [classical dengue]),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -77,A91,(dengue haemorrhagic fever),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -78,A92,(other mosquito-borne viral fevers),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -79,A93,"(other arthropod-borne viral fevers, not elsewhere classified)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -80,A94,(unspecified arthropod-borne viral fever),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -81,A95,(yellow fever),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -82,A97,(dengue),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -83,A98,"(other viral haemorrhagic fevers, not elsewhere classified)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -84,B00,(herpesviral [herpes simplex] infections),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -85,B01,(varicella [chickenpox]),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -86,B02,(zoster [herpes zoster]),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -87,B03,(smallpox),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -88,B05,(measles),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -89,B06,(rubella [german measles]),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -90,B07,(viral warts),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -91,B08,"(other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -92,B09,(unspecified viral infection characterised by skin and mucous membrane lesions),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -93,B15,(acute hepatitis a),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -94,B16,(acute hepatitis b),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -95,B17,(other acute viral hepatitis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -96,B18,(chronic viral hepatitis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -97,B19,(unspecified viral hepatitis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -98,B20,(human immunodeficiency virus [hiv] disease resulting in infectious and parasitic diseases),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -99,B21,(human immunodeficiency virus [hiv] disease resulting in malignant neoplasms),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -100,B22,(human immunodeficiency virus [hiv] disease resulting in other specified diseases),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -101,B23,(human immunodeficiency virus [hiv] disease resulting in other conditions),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -102,B24,(unspecified human immunodeficiency virus [hiv] disease),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -103,B25,(cytomegaloviral disease),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -104,B26,(mumps),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -105,B27,(infectious mononucleosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -106,B30,(viral conjunctivitis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -107,B33,"(other viral diseases, not elsewhere classified)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -108,B34,(viral infection of unspecified site),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -109,B35,(dermatophytosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -110,B36,(other superficial mycoses),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -111,B37,(candidiasis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -112,B38,(coccidioidomycosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -113,B39,(histoplasmosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -114,B40,(blastomycosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -115,B42,(sporotrichosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -116,B43,(chromomycosis and phaeomycotic abscess),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -117,B44,(aspergillosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -118,B45,(cryptococcosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -119,B46,(zygomycosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -120,B47,(mycetoma),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -121,B48,"(other mycoses, not elsewhere classified)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -122,B49,(unspecified mycosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -123,B50,(plasmodium falciparum malaria),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -124,B51,(plasmodium vivax malaria),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -125,B52,(plasmodium malariae malaria),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -126,B53,(other parasitologically confirmed malaria),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -127,B54,(unspecified malaria),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -128,B55,(leishmaniasis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -129,B57,(chagas' disease),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -130,B58,(toxoplasmosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -131,B59,(pneumocystosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -132,B60,"(other protozoal diseases, not elsewhere classified)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -133,B65,(schistosomiasis [bilharziasis]),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -134,B66,(other fluke infections),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -135,B67,(echinococcosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -136,B68,(taeniasis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -137,B69,(cysticercosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -138,B71,(other cestode infections),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -139,B73,(onchocerciasis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -140,B74,(filariasis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -141,B75,(trichinellosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -142,B76,(hookworm diseases),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -143,B77,(ascariasis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -144,B78,(strongyloidiasis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -145,B79,(trichuriasis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -146,B80,(enterobiasis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -147,B81,"(other intestinal helminthiases, not elsewhere classified)",I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -148,B82,(unspecified intestinal parasitism),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -149,B83,(other helminthiases),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -150,B85,(pediculosis and phthiriasis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -151,B86,(scabies),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -152,B87,(myiasis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -153,B88,(other infestations),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -154,B89,(unspecified parasitic disease),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -155,B90,(sequelae of tuberculosis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -156,B91,(sequelae of poliomyelitis),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -157,B94,(sequelae of other and unspecified infectious and parasitic diseases),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -158,B95,(streptococcus and staphylococcus as the cause of diseases classified to other chapters),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -159,B96,(other bacterial agents as the cause of diseases classified to other chapters),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -160,B97,(viral agents as the cause of diseases classified to other chapters),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -161,B98,(other specified infectious agents as the cause of diseases classified to other chapters),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -162,B99,(other and unspecified infectious diseases),I,Certain infectious and parasitic diseases,infection_immune,1.0,icd10_chapter_range -163,D50,(iron deficiency anaemia),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -164,D51,(vitamin b12 deficiency anaemia),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -165,D52,(folate deficiency anaemia),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -166,D53,(other nutritional anaemias),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -167,D55,(anaemia due to enzyme disorders),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -168,D56,(thalassaemia),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -169,D57,(sickle-cell disorders),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -170,D58,(other hereditary haemolytic anaemias),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -171,D59,(acquired haemolytic anaemia),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -172,D60,(acquired pure red cell aplasia [erythroblastopenia]),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -173,D61,(other aplastic anaemias),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -174,D62,(acute posthaemorrhagic anaemia),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -175,D63,(anaemia in chronic diseases classified elsewhere),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -176,D64,(other anaemias),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -177,D65,(disseminated intravascular coagulation [defibrination syndrome]),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -178,D66,(hereditary factor viii deficiency),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -179,D67,(hereditary factor ix deficiency),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -180,D68,(other coagulation defects),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -181,D69,(purpura and other haemorrhagic conditions),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -182,D70,(agranulocytosis),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -183,D71,(functional disorders of polymorphonuclear neutrophils),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -184,D72,(other disorders of white blood cells),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -185,D73,(diseases of spleen),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -186,D74,(methaemoglobinaemia),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -187,D75,(other diseases of blood and blood-forming organs),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -188,D76,(certain diseases involving lymphoreticular tissue and reticulohistiocytic system),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -189,D77,(other disorders of blood and blood-forming organs in diseases classified elsewhere),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -190,D80,(immunodeficiency with predominantly antibody defects),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -191,D81,(combined immunodeficiencies),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -192,D82,(immunodeficiency associated with other major defects),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -193,D83,(common variable immunodeficiency),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -194,D84,(other immunodeficiencies),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -195,D86,(sarcoidosis),III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -196,D89,"(other disorders involving the immune mechanism, not elsewhere classified)",III,Diseases of the blood and immune mechanism,hematologic_immune,1.0,icd10_chapter_range -197,E01,(iodine-deficiency-related thyroid disorders and allied conditions),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -198,E02,(subclinical iodine-deficiency hypothyroidism),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -199,E03,(other hypothyroidism),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -200,E04,(other non-toxic goitre),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -201,E05,(thyrotoxicosis [hyperthyroidism]),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -202,E06,(thyroiditis),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -203,E07,(other disorders of thyroid),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -204,E10,(insulin-dependent diabetes mellitus),IV,"Endocrine, nutritional and metabolic diseases",diabetes_metabolic,1.0,icd10_chapter_range -205,E11,(non-insulin-dependent diabetes mellitus),IV,"Endocrine, nutritional and metabolic diseases",diabetes_metabolic,1.0,icd10_chapter_range -206,E12,(malnutrition-related diabetes mellitus),IV,"Endocrine, nutritional and metabolic diseases",diabetes_metabolic,1.0,icd10_chapter_range -207,E13,(other specified diabetes mellitus),IV,"Endocrine, nutritional and metabolic diseases",diabetes_metabolic,1.0,icd10_chapter_range -208,E14,(unspecified diabetes mellitus),IV,"Endocrine, nutritional and metabolic diseases",diabetes_metabolic,1.0,icd10_chapter_range -209,E15,(nondiabetic hypoglycaemic coma),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -210,E16,(other disorders of pancreatic internal secretion),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -211,E20,(hypoparathyroidism),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -212,E21,(hyperparathyroidism and other disorders of parathyroid gland),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -213,E22,(hyperfunction of pituitary gland),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -214,E23,(hypofunction and other disorders of pituitary gland),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -215,E24,(cushing's syndrome),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -216,E25,(adrenogenital disorders),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -217,E26,(hyperaldosteronism),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -218,E27,(other disorders of adrenal gland),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -219,E28,(ovarian dysfunction),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -220,E29,(testicular dysfunction),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -221,E30,"(disorders of puberty, not elsewhere classified)",IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -222,E31,(polyglandular dysfunction),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -223,E32,(diseases of thymus),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -224,E34,(other endocrine disorders),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -225,E35,(disorders of endocrine glands in diseases classified elsewhere),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -226,E41,(nutritional marasmus),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -227,E43,(unspecified severe protein-energy malnutrition),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -228,E44,(protein-energy malnutrition of moderate and mild degree),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -229,E45,(retarded development following protein-energy malnutrition),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -230,E46,(unspecified protein-energy malnutrition),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -231,E50,(vitamin a deficiency),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -232,E51,(thiamine deficiency),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -233,E52,(niacin deficiency [pellagra]),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -234,E53,(deficiency of other b group vitamins),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -235,E54,(ascorbic acid deficiency),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -236,E55,(vitamin d deficiency),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -237,E56,(other vitamin deficiencies),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -238,E58,(dietary calcium deficiency),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -239,E59,(dietary selenium deficiency),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -240,E60,(dietary zinc deficiency),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -241,E61,(deficiency of other nutrient elements),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -242,E63,(other nutritional deficiencies),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -243,E64,(sequelae of malnutrition and other nutritional deficiencies),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -244,E65,(localised adiposity),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -245,E66,(obesity),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -246,E67,(other hyperalimentation),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -247,E68,(sequelae of hyperalimentation),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -248,E70,(disorders of aromatic amino-acid metabolism),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -249,E71,(disorders of branched-chain amino-acid metabolism and fatty-acid metabolism),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -250,E72,(other disorders of amino-acid metabolism),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -251,E73,(lactose intolerance),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -252,E74,(other disorders of carbohydrate metabolism),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -253,E75,(disorders of sphingolipid metabolism and other lipid storage disorders),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -254,E76,(disorders of glycosaminoglycan metabolism),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -255,E77,(disorders of glycoprotein metabolism),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -256,E78,(disorders of lipoprotein metabolism and other lipidaemias),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -257,E79,(disorders of purine and pyrimidine metabolism),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -258,E80,(disorders of porphyrin and bilirubin metabolism),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -259,E83,(disorders of mineral metabolism),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -260,E84,(cystic fibrosis),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -261,E85,(amyloidosis),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -262,E86,(volume depletion),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -263,E87,"(other disorders of fluid, electrolyte and acid-base balance)",IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -264,E88,(other metabolic disorders),IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -265,E89,"(postprocedural endocrine and metabolic disorders, not elsewhere classified)",IV,"Endocrine, nutritional and metabolic diseases",metabolic_endocrine,1.0,icd10_chapter_range -266,F00,(dementia in alzheimer's disease),V,Mental and behavioural disorders,cognition_neuropsychiatric,1.0,icd10_chapter_range -267,F01,(vascular dementia),V,Mental and behavioural disorders,cognition_neuropsychiatric,1.0,icd10_chapter_range -268,F02,(dementia in other diseases classified elsewhere),V,Mental and behavioural disorders,cognition_neuropsychiatric,1.0,icd10_chapter_range -269,F03,(unspecified dementia),V,Mental and behavioural disorders,cognition_neuropsychiatric,1.0,icd10_chapter_range -270,F04,"(organic amnesic syndrome, not induced by alcohol and other psychoactive substances)",V,Mental and behavioural disorders,cognition_neuropsychiatric,1.0,icd10_chapter_range -271,F05,"(delirium, not induced by alcohol and other psychoactive substances)",V,Mental and behavioural disorders,cognition_neuropsychiatric,1.0,icd10_chapter_range -272,F06,(other mental disorders due to brain damage and dysfunction and to physical disease),V,Mental and behavioural disorders,cognition_neuropsychiatric,1.0,icd10_chapter_range -273,F07,"(personality and behavioural disorders due to brain disease, damage and dysfunction)",V,Mental and behavioural disorders,cognition_neuropsychiatric,1.0,icd10_chapter_range -274,F09,(unspecified organic or symptomatic mental disorder),V,Mental and behavioural disorders,cognition_neuropsychiatric,1.0,icd10_chapter_range -275,F10,(mental and behavioural disorders due to use of alcohol),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -276,F11,(mental and behavioural disorders due to use of opioids),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -277,F12,(mental and behavioural disorders due to use of cannabinoids),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -278,F13,(mental and behavioural disorders due to use of sedatives or hypnotics),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -279,F14,(mental and behavioural disorders due to use of cocaine),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -280,F15,"(mental and behavioural disorders due to use of other stimulants, including caffeine)",V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -281,F16,(mental and behavioural disorders due to use of hallucinogens),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -282,F17,(mental and behavioural disorders due to use of tobacco),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -283,F18,(mental and behavioural disorders due to use of volatile solvents),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -284,F19,(mental and behavioural disorders due to multiple drug use and use of other psychoactive substances),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -285,F20,(schizophrenia),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -286,F21,(schizotypal disorder),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -287,F22,(persistent delusional disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -288,F23,(acute and transient psychotic disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -289,F24,(induced delusional disorder),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -290,F25,(schizoaffective disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -291,F28,(other nonorganic psychotic disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -292,F29,(unspecified nonorganic psychosis),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -293,F30,(manic episode),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -294,F31,(bipolar affective disorder),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -295,F32,(depressive episode),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -296,F33,(recurrent depressive disorder),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -297,F34,(persistent mood [affective] disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -298,F38,(other mood [affective] disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -299,F39,(unspecified mood [affective] disorder),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -300,F40,(phobic anxiety disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -301,F41,(other anxiety disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -302,F42,(obsessive-compulsive disorder),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -303,F43,"(reaction to severe stress, and adjustment disorders)",V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -304,F44,(dissociative [conversion] disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -305,F45,(somatoform disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -306,F48,(other neurotic disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -307,F50,(eating disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -308,F51,(nonorganic sleep disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -309,F52,"(sexual dysfunction, not caused by organic disorder or disease)",V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -310,F53,"(mental and behavioural disorders associated with the puerperium, not elsewhere classified)",V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -311,F54,(psychological and behavioural factors associated with disorders or diseases classified elsewhere),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -312,F55,(abuse of non-dependence-producing substances),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -313,F59,(unspecified behavioural syndromes associated with physiological disturbances and physical factors),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -314,F60,(specific personality disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -315,F61,(mixed and other personality disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -316,F62,"(enduring personality changes, not attributable to brain damage and disease)",V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -317,F63,(habit and impulse disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -318,F64,(gender identity disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -319,F65,(disorders of sexual preference),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -320,F66,(psychological and behavioural disorders associated with sexual development and orientation),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -321,F68,(other disorders of adult personality and behaviour),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -322,F69,(unspecified disorder of adult personality and behaviour),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -323,F70,(mild mental retardation),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -324,F71,(moderate mental retardation),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -325,F72,(severe mental retardation),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -326,F78,(other mental retardation),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -327,F79,(unspecified mental retardation),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -328,F80,(specific developmental disorders of speech and language),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -329,F81,(specific developmental disorders of scholastic skills),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -330,F82,(specific developmental disorder of motor function),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -331,F83,(mixed specific developmental disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -332,F84,(pervasive developmental disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -333,F88,(other disorders of psychological development),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -334,F89,(unspecified disorder of psychological development),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -335,F90,(hyperkinetic disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -336,F91,(conduct disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -337,F92,(mixed disorders of conduct and emotions),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -338,F93,(emotional disorders with onset specific to childhood),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -339,F94,(disorders of social functioning with onset specific to childhood and adolescence),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -340,F95,(tic disorders),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -341,F98,(other behavioural and emotional disorders with onset usually occurring in childhood and adolescence),V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -342,F99,"(mental disorder, not otherwise specified)",V,Mental and behavioural disorders,mental_behavioral,1.0,icd10_chapter_range -343,G00,"(bacterial meningitis, not elsewhere classified)",VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -344,G01,(meningitis in bacterial diseases classified elsewhere),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -345,G02,(meningitis in other infectious and parasitic diseases classified elsewhere),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -346,G03,(meningitis due to other and unspecified causes),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -347,G04,"(encephalitis, myelitis and encephalomyelitis)",VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -348,G05,"(encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere)",VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -349,G06,(intracranial and intraspinal abscess and granuloma),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -350,G07,(intracranial and intraspinal abscess and granuloma in diseases classified elsewhere),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -351,G08,(intracranial and intraspinal phlebitis and thrombophlebitis),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -352,G09,(sequelae of inflammatory diseases of central nervous system),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -353,G10,(huntington's disease),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -354,G11,(hereditary ataxia),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -355,G12,(spinal muscular atrophy and related syndromes),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -356,G13,(systemic atrophies primarily affecting central nervous system in diseases classified elsewhere),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -357,G14,(postpolio syndrome),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -358,G20,(parkinson's disease),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -359,G21,(secondary parkinsonism),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -360,G22,(parkinsonism in diseases classified elsewhere),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -361,G23,(other degenerative diseases of basal ganglia),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -362,G24,(dystonia),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -363,G25,(other extrapyramidal and movement disorders),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -364,G30,(alzheimer's disease),VI,Diseases of the nervous system,cognition_neurodegenerative,1.0,icd10_chapter_range -365,G31,"(other degenerative diseases of nervous system, not elsewhere classified)",VI,Diseases of the nervous system,cognition_neurodegenerative,1.0,icd10_chapter_range -366,G32,(other degenerative disorders of nervous system in diseases classified elsewhere),VI,Diseases of the nervous system,cognition_neurodegenerative,1.0,icd10_chapter_range -367,G35,(multiple sclerosis),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -368,G36,(other acute disseminated demyelination),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -369,G37,(other demyelinating diseases of central nervous system),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -370,G40,(epilepsy),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -371,G41,(status epilepticus),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -372,G43,(migraine),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -373,G44,(other headache syndromes),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -374,G45,(transient cerebral ischaemic attacks and related syndromes),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -375,G46,(vascular syndromes of brain in cerebrovascular diseases),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -376,G47,(sleep disorders),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -377,G50,(disorders of trigeminal nerve),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -378,G51,(facial nerve disorders),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -379,G52,(disorders of other cranial nerves),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -380,G53,(cranial nerve disorders in diseases classified elsewhere),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -381,G54,(nerve root and plexus disorders),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -382,G55,(nerve root and plexus compressions in diseases classified elsewhere),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -383,G56,(mononeuropathies of upper limb),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -384,G57,(mononeuropathies of lower limb),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -385,G58,(other mononeuropathies),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -386,G59,(mononeuropathy in diseases classified elsewhere),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -387,G60,(hereditary and idiopathic neuropathy),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -388,G61,(inflammatory polyneuropathy),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -389,G62,(other polyneuropathies),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -390,G63,(polyneuropathy in diseases classified elsewhere),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -391,G64,(other disorders of peripheral nervous system),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -392,G70,(myasthenia gravis and other myoneural disorders),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -393,G71,(primary disorders of muscles),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -394,G72,(other myopathies),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -395,G73,(disorders of myoneural junction and muscle in diseases classified elsewhere),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -396,G80,(infantile cerebral palsy),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -397,G81,(hemiplegia),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -398,G82,(paraplegia and tetraplegia),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -399,G83,(other paralytic syndromes),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -400,G90,(disorders of autonomic nervous system),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -401,G91,(hydrocephalus),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -402,G92,(toxic encephalopathy),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -403,G93,(other disorders of brain),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -404,G94,(other disorders of brain in diseases classified elsewhere),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -405,G95,(other diseases of spinal cord),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -406,G96,(other disorders of central nervous system),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -407,G97,"(postprocedural disorders of nervous system, not elsewhere classified)",VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -408,G98,"(other disorders of nervous system, not elsewhere classified)",VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -409,G99,(other disorders of nervous system in diseases classified elsewhere),VI,Diseases of the nervous system,neurologic,1.0,icd10_chapter_range -410,H00,(hordeolum and chalazion),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -411,H01,(other inflammation of eyelid),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -412,H02,(other disorders of eyelid),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -413,H03,(disorders of eyelid in diseases classified elsewhere),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -414,H04,(disorders of lachrymal system),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -415,H05,(disorders of orbit),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -416,H06,(disorders of lachrymal system and orbit in diseases classified elsewhere),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -417,H10,(conjunctivitis),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -418,H11,(other disorders of conjunctiva),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -419,H13,(disorders of conjunctiva in diseases classified elsewhere),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -420,H15,(disorders of sclera),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -421,H16,(keratitis),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -422,H17,(corneal scars and opacities),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -423,H18,(other disorders of cornea),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -424,H19,(disorders of sclera and cornea in diseases classified elsewhere),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -425,H20,(iridocyclitis),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -426,H21,(other disorders of iris and ciliary body),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -427,H22,(disorders of iris and ciliary body in diseases classified elsewhere),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -428,H25,(senile cataract),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -429,H26,(other cataract),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -430,H27,(other disorders of lens),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -431,H28,(cataract and other disorders of lens in diseases classified elsewhere),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -432,H30,(chorioretinal inflammation),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -433,H31,(other disorders of choroid),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -434,H32,(chorioretinal disorders in diseases classified elsewhere),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -435,H33,(retinal detachments and breaks),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -436,H34,(retinal vascular occlusions),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -437,H35,(other retinal disorders),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -438,H36,(retinal disorders in diseases classified elsewhere),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -439,H40,(glaucoma),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -440,H42,(glaucoma in diseases classified elsewhere),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -441,H43,(disorders of vitreous body),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -442,H44,(disorders of globe),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -443,H45,(disorders of vitreous body and globe in diseases classified elsewhere),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -444,H46,(optic neuritis),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -445,H47,(other disorders of optic [2nd] nerve and visual pathways),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -446,H48,(disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -447,H49,(paralytic strabismus),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -448,H50,(other strabismus),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -449,H51,(other disorders of binocular movement),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -450,H52,(disorders of refraction and accommodation),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -451,H53,(visual disturbances),VII,Diseases of the eye and adnexa,sensory_vision,1.0,icd10_chapter_range -452,H54,(blindness and low vision),VII,Diseases of the eye and adnexa,sensory_vision,1.0,icd10_chapter_range -453,H55,(nystagmus and other irregular eye movements),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -454,H57,(other disorders of eye and adnexa),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -455,H58,(other disorders of eye and adnexa in diseases classified elsewhere),VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -456,H59,"(postprocedural disorders of eye and adnexa, not elsewhere classified)",VII,Diseases of the eye and adnexa,sensory_eye,1.0,icd10_chapter_range -457,H60,(otitis externa),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -458,H61,(other disorders of external ear),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -459,H62,(disorders of external ear in diseases classified elsewhere),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -460,H65,(nonsuppurative otitis media),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -461,H66,(suppurative and unspecified otitis media),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -462,H67,(otitis media in diseases classified elsewhere),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -463,H68,(eustachian salpingitis and obstruction),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -464,H69,(other disorders of eustachian tube),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -465,H70,(mastoiditis and related conditions),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -466,H71,(cholesteatoma of middle ear),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -467,H72,(perforation of tympanic membrane),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -468,H73,(other disorders of tympanic membrane),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -469,H74,(other disorders of middle ear and mastoid),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -470,H75,(other disorders of middle ear and mastoid in diseases classified elsewhere),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -471,H80,(otosclerosis),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -472,H81,(disorders of vestibular function),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -473,H82,(vertiginous syndromes in diseases classified elsewhere),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -474,H83,(other diseases of inner ear),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -475,H90,(conductive and sensorineural hearing loss),VIII,Diseases of the ear and mastoid process,sensory_hearing,1.0,icd10_chapter_range -476,H91,(other hearing loss),VIII,Diseases of the ear and mastoid process,sensory_hearing,1.0,icd10_chapter_range -477,H92,(otalgia and effusion of ear),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -478,H93,"(other disorders of ear, not elsewhere classified)",VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -479,H94,(other disorders of ear in diseases classified elsewhere),VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -480,H95,"(postprocedural disorders of ear and mastoid process, not elsewhere classified)",VIII,Diseases of the ear and mastoid process,sensory_ear,1.0,icd10_chapter_range -481,I00,(rheumatic fever without mention of heart involvement),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -482,I01,(rheumatic fever with heart involvement),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -483,I02,(rheumatic chorea),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -484,I05,(rheumatic mitral valve diseases),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -485,I06,(rheumatic aortic valve diseases),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -486,I07,(rheumatic tricuspid valve diseases),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -487,I08,(multiple valve diseases),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -488,I09,(other rheumatic heart diseases),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -489,I10,(essential (primary) hypertension),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -490,I11,(hypertensive heart disease),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -491,I12,(hypertensive renal disease),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -492,I13,(hypertensive heart and renal disease),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -493,I15,(secondary hypertension),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -494,I20,(angina pectoris),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -495,I21,(acute myocardial infarction),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -496,I22,(subsequent myocardial infarction),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -497,I23,(certain current complications following acute myocardial infarction),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -498,I24,(other acute ischaemic heart diseases),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -499,I25,(chronic ischaemic heart disease),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -500,I26,(pulmonary embolism),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -501,I27,(other pulmonary heart diseases),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -502,I28,(other diseases of pulmonary vessels),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -503,I30,(acute pericarditis),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -504,I31,(other diseases of pericardium),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -505,I32,(pericarditis in diseases classified elsewhere),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -506,I33,(acute and subacute endocarditis),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -507,I34,(nonrheumatic mitral valve disorders),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -508,I35,(nonrheumatic aortic valve disorders),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -509,I36,(nonrheumatic tricuspid valve disorders),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -510,I37,(pulmonary valve disorders),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -511,I38,"(endocarditis, valve unspecified)",IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -512,I39,(endocarditis and heart valve disorders in diseases classified elsewhere),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -513,I40,(acute myocarditis),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -514,I41,(myocarditis in diseases classified elsewhere),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -515,I42,(cardiomyopathy),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -516,I43,(cardiomyopathy in diseases classified elsewhere),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -517,I44,(atrioventricular and left bundle-branch block),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -518,I45,(other conduction disorders),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -519,I46,(cardiac arrest),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -520,I47,(paroxysmal tachycardia),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -521,I48,(atrial fibrillation and flutter),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -522,I49,(other cardiac arrhythmias),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -523,I50,(heart failure),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -524,I51,(complications and ill-defined descriptions of heart disease),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -525,I52,(other heart disorders in diseases classified elsewhere),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -526,I60,(subarachnoid haemorrhage),IX,Diseases of the circulatory system,brain_vascular,1.0,icd10_chapter_range -527,I61,(intracerebral haemorrhage),IX,Diseases of the circulatory system,brain_vascular,1.0,icd10_chapter_range -528,I62,(other nontraumatic intracranial haemorrhage),IX,Diseases of the circulatory system,brain_vascular,1.0,icd10_chapter_range -529,I63,(cerebral infarction),IX,Diseases of the circulatory system,brain_vascular,1.0,icd10_chapter_range -530,I64,"(stroke, not specified as haemorrhage or infarction)",IX,Diseases of the circulatory system,brain_vascular,1.0,icd10_chapter_range -531,I65,"(occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction)",IX,Diseases of the circulatory system,brain_vascular,1.0,icd10_chapter_range -532,I66,"(occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction)",IX,Diseases of the circulatory system,brain_vascular,1.0,icd10_chapter_range -533,I67,(other cerebrovascular diseases),IX,Diseases of the circulatory system,brain_vascular,1.0,icd10_chapter_range -534,I68,(cerebrovascular disorders in diseases classified elsewhere),IX,Diseases of the circulatory system,brain_vascular,1.0,icd10_chapter_range -535,I69,(sequelae of cerebrovascular disease),IX,Diseases of the circulatory system,brain_vascular,1.0,icd10_chapter_range -536,I70,(atherosclerosis),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -537,I71,(aortic aneurysm and dissection),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -538,I72,(other aneurysm),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -539,I73,(other peripheral vascular diseases),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -540,I74,(arterial embolism and thrombosis),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -541,I77,(other disorders of arteries and arterioles),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -542,I78,(diseases of capillaries),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -543,I79,"(disorders of arteries, arterioles and capillaries in diseases classified elsewhere)",IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -544,I80,(phlebitis and thrombophlebitis),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -545,I81,(portal vein thrombosis),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -546,I82,(other venous embolism and thrombosis),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -547,I83,(varicose veins of lower extremities),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -548,I84,(haemorrhoids),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -549,I85,(oesophageal varices),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -550,I86,(varicose veins of other sites),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -551,I87,(other disorders of veins),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -552,I88,(nonspecific lymphadenitis),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -553,I89,(other non-infective disorders of lymphatic vessels and lymph nodes),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -554,I95,(hypotension),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -555,I97,"(postprocedural disorders of circulatory system, not elsewhere classified)",IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -556,I98,(other disorders of circulatory system in diseases classified elsewhere),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -557,I99,(other and unspecified disorders of circulatory system),IX,Diseases of the circulatory system,cardiovascular,1.0,icd10_chapter_range -558,J00,(acute nasopharyngitis [common cold]),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -559,J01,(acute sinusitis),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -560,J02,(acute pharyngitis),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -561,J03,(acute tonsillitis),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -562,J04,(acute laryngitis and tracheitis),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -563,J05,(acute obstructive laryngitis [croup] and epiglottitis),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -564,J06,(acute upper respiratory infections of multiple and unspecified sites),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -565,J09,(influenza due to certain identified influenza virus),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -566,J10,(influenza due to identified influenza virus),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -567,J11,"(influenza, virus not identified)",X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -568,J12,"(viral pneumonia, not elsewhere classified)",X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -569,J13,(pneumonia due to streptococcus pneumoniae),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -570,J14,(pneumonia due to haemophilus influenzae),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -571,J15,"(bacterial pneumonia, not elsewhere classified)",X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -572,J16,"(pneumonia due to other infectious organisms, not elsewhere classified)",X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -573,J17,(pneumonia in diseases classified elsewhere),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -574,J18,"(pneumonia, organism unspecified)",X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -575,J20,(acute bronchitis),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -576,J21,(acute bronchiolitis),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -577,J22,(unspecified acute lower respiratory infection),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -578,J30,(vasomotor and allergic rhinitis),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -579,J31,"(chronic rhinitis, nasopharyngitis and pharyngitis)",X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -580,J32,(chronic sinusitis),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -581,J33,(nasal polyp),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -582,J34,(other disorders of nose and nasal sinuses),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -583,J35,(chronic diseases of tonsils and adenoids),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -584,J36,(peritonsillar abscess),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -585,J37,(chronic laryngitis and laryngotracheitis),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -586,J38,"(diseases of vocal cords and larynx, not elsewhere classified)",X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -587,J39,(other diseases of upper respiratory tract),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -588,J40,"(bronchitis, not specified as acute or chronic)",X,Diseases of the respiratory system,chronic_respiratory,1.0,icd10_chapter_range -589,J41,(simple and mucopurulent chronic bronchitis),X,Diseases of the respiratory system,chronic_respiratory,1.0,icd10_chapter_range -590,J42,(unspecified chronic bronchitis),X,Diseases of the respiratory system,chronic_respiratory,1.0,icd10_chapter_range -591,J43,(emphysema),X,Diseases of the respiratory system,chronic_respiratory,1.0,icd10_chapter_range -592,J44,(other chronic obstructive pulmonary disease),X,Diseases of the respiratory system,chronic_respiratory,1.0,icd10_chapter_range -593,J45,(asthma),X,Diseases of the respiratory system,chronic_respiratory,1.0,icd10_chapter_range -594,J46,(status asthmaticus),X,Diseases of the respiratory system,chronic_respiratory,1.0,icd10_chapter_range -595,J47,(bronchiectasis),X,Diseases of the respiratory system,chronic_respiratory,1.0,icd10_chapter_range -596,J60,(coalworker's pneumoconiosis),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -597,J61,(pneumoconiosis due to asbestos and other mineral fibres),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -598,J62,(pneumoconiosis due to dust containing silica),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -599,J63,(pneumoconiosis due to other inorganic dusts),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -600,J64,(unspecified pneumoconiosis),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -601,J66,(airway disease due to specific organic dust),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -602,J67,(hypersensitivity pneumonitis due to organic dust),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -603,J68,"(respiratory conditions due to inhalation of chemicals, gases, fumes and vapours)",X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -604,J69,(pneumonitis due to solids and liquids),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -605,J70,(respiratory conditions due to other external agents),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -606,J80,(adult respiratory distress syndrome),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -607,J81,(pulmonary oedema),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -608,J82,"(pulmonary eosinophilia, not elsewhere classified)",X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -609,J84,(other interstitial pulmonary diseases),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -610,J85,(abscess of lung and mediastinum),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -611,J86,(pyothorax),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -612,J90,"(pleural effusion, not elsewhere classified)",X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -613,J91,(pleural effusion in conditions classified elsewhere),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -614,J92,(pleural plaque),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -615,J93,(pneumothorax),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -616,J94,(other pleural conditions),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -617,J95,"(postprocedural respiratory disorders, not elsewhere classified)",X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -618,J96,"(respiratory failure, not elsewhere classified)",X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -619,J98,(other respiratory disorders),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -620,J99,(respiratory disorders in diseases classified elsewhere),X,Diseases of the respiratory system,respiratory,1.0,icd10_chapter_range -621,K00,(disorders of tooth development and eruption),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -622,K01,(embedded and impacted teeth),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -623,K02,(dental caries),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -624,K03,(other diseases of hard tissues of teeth),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -625,K04,(diseases of pulp and periapical tissues),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -626,K05,(gingivitis and periodontal diseases),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -627,K06,(other disorders of gingiva and edentulous alveolar ridge),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -628,K07,(dentofacial anomalies [including malocclusion]),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -629,K08,(other disorders of teeth and supporting structures),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -630,K09,"(cysts of oral region, not elsewhere classified)",XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -631,K10,(other diseases of jaws),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -632,K11,(diseases of salivary glands),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -633,K12,(stomatitis and related lesions),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -634,K13,(other diseases of lip and oral mucosa),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -635,K14,(diseases of tongue),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -636,K20,(oesophagitis),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -637,K21,(gastro-oesophageal reflux disease),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -638,K22,(other diseases of oesophagus),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -639,K23,(disorders of oesophagus in diseases classified elsewhere),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -640,K25,(gastric ulcer),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -641,K26,(duodenal ulcer),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -642,K27,"(peptic ulcer, site unspecified)",XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -643,K28,(gastrojejunal ulcer),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -644,K29,(gastritis and duodenitis),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -645,K30,(dyspepsia),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -646,K31,(other diseases of stomach and duodenum),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -647,K35,(acute appendicitis),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -648,K36,(other appendicitis),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -649,K37,(unspecified appendicitis),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -650,K38,(other diseases of appendix),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -651,K40,(inguinal hernia),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -652,K41,(femoral hernia),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -653,K42,(umbilical hernia),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -654,K43,(ventral hernia),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -655,K44,(diaphragmatic hernia),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -656,K45,(other abdominal hernia),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -657,K46,(unspecified abdominal hernia),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -658,K50,(crohn's disease [regional enteritis]),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -659,K51,(ulcerative colitis),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -660,K52,(other non-infective gastro-enteritis and colitis),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -661,K55,(vascular disorders of intestine),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -662,K56,(paralytic ileus and intestinal obstruction without hernia),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -663,K57,(diverticular disease of intestine),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -664,K58,(irritable bowel syndrome),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -665,K59,(other functional intestinal disorders),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -666,K60,(fissure and fistula of anal and rectal regions),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -667,K61,(abscess of anal and rectal regions),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -668,K62,(other diseases of anus and rectum),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -669,K63,(other diseases of intestine),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -670,K64,(haemorrhoids and perianal venous thrombosis),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -671,K65,(peritonitis),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -672,K66,(other disorders of peritoneum),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -673,K67,(disorders of peritoneum in infectious diseases classified elsewhere),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -674,K70,(alcoholic liver disease),XI,Diseases of the digestive system,liver,1.0,icd10_chapter_range -675,K71,(toxic liver disease),XI,Diseases of the digestive system,liver,1.0,icd10_chapter_range -676,K72,"(hepatic failure, not elsewhere classified)",XI,Diseases of the digestive system,liver,1.0,icd10_chapter_range -677,K73,"(chronic hepatitis, not elsewhere classified)",XI,Diseases of the digestive system,liver,1.0,icd10_chapter_range -678,K74,(fibrosis and cirrhosis of liver),XI,Diseases of the digestive system,liver,1.0,icd10_chapter_range -679,K75,(other inflammatory liver diseases),XI,Diseases of the digestive system,liver,1.0,icd10_chapter_range -680,K76,(other diseases of liver),XI,Diseases of the digestive system,liver,1.0,icd10_chapter_range -681,K77,(liver disorders in diseases classified elsewhere),XI,Diseases of the digestive system,liver,1.0,icd10_chapter_range -682,K80,(cholelithiasis),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -683,K81,(cholecystitis),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -684,K82,(other diseases of gallbladder),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -685,K83,(other diseases of biliary tract),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -686,K85,(acute pancreatitis),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -687,K86,(other diseases of pancreas),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -688,K87,"(disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere)",XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -689,K90,(intestinal malabsorption),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -690,K91,"(postprocedural disorders of digestive system, not elsewhere classified)",XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -691,K92,(other diseases of digestive system),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -692,K93,(disorders of other digestive organs in diseases classified elsewhere),XI,Diseases of the digestive system,digestive_liver,1.0,icd10_chapter_range -693,L00,(staphylococcal scalded skin syndrome),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -694,L01,(impetigo),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -695,L02,"(cutaneous abscess, furuncle and carbuncle)",XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -696,L03,(cellulitis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -697,L04,(acute lymphadenitis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -698,L05,(pilonidal cyst),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -699,L08,(other local infections of skin and subcutaneous tissue),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -700,L10,(pemphigus),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -701,L11,(other acantholytic disorders),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -702,L12,(pemphigoid),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -703,L13,(other bullous disorders),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -704,L14,(bullous disorders in diseases classified elsewhere),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -705,L20,(atopic dermatitis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -706,L21,(seborrhoeic dermatitis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -707,L22,(diaper [napkin] dermatitis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -708,L23,(allergic contact dermatitis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -709,L24,(irritant contact dermatitis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -710,L25,(unspecified contact dermatitis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -711,L26,(exfoliative dermatitis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -712,L27,(dermatitis due to substances taken internally),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -713,L28,(lichen simplex chronicus and prurigo),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -714,L29,(pruritus),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -715,L30,(other dermatitis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -716,L40,(psoriasis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -717,L41,(parapsoriasis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -718,L42,(pityriasis rosea),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -719,L43,(lichen planus),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -720,L44,(other papulosquamous disorders),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -721,L50,(urticaria),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -722,L51,(erythema multiforme),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -723,L52,(erythema nodosum),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -724,L53,(other erythematous conditions),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -725,L54,(erythema in diseases classified elsewhere),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -726,L55,(sunburn),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -727,L56,(other acute skin changes due to ultraviolet radiation),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -728,L57,(skin changes due to chronic exposure to nonionising radiation),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -729,L58,(radiodermatitis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -730,L59,(other disorders of skin and subcutaneous tissue related to radiation),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -731,L60,(nail disorders),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -732,L62,(nail disorders in diseases classified elsewhere),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -733,L63,(alopecia areata),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -734,L64,(androgenic alopecia),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -735,L65,(other nonscarring hair loss),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -736,L66,(cicatricial alopecia [scarring hair loss]),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -737,L67,(hair colour and hair shaft abnormalities),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -738,L68,(hypertrichosis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -739,L70,(acne),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -740,L71,(rosacea),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -741,L72,(follicular cysts of skin and subcutaneous tissue),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -742,L73,(other follicular disorders),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -743,L74,(eccrine sweat disorders),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -744,L75,(apocrine sweat disorders),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -745,L80,(vitiligo),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -746,L81,(other disorders of pigmentation),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -747,L82,(seborrhoeic keratosis),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -748,L83,(acanthosis nigricans),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -749,L84,(corns and callosities),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -750,L85,(other epidermal thickening),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -751,L86,(keratoderma in diseases classified elsewhere),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -752,L87,(transepidermal elimination disorders),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -753,L88,(pyoderma gangrenosum),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -754,L89,(decubitus ulcer),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -755,L90,(atrophic disorders of skin),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -756,L91,(hypertrophic disorders of skin),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -757,L92,(granulomatous disorders of skin and subcutaneous tissue),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -758,L93,(lupus erythematosus),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -759,L94,(other localised connective tissue disorders),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -760,L95,"(vasculitis limited to skin, not elsewhere classified)",XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -761,L97,"(ulcer of lower limb, not elsewhere classified)",XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -762,L98,"(other disorders of skin and subcutaneous tissue, not elsewhere classified)",XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -763,L99,(other disorders of skin and subcutaneous tissue in diseases classified elsewhere),XII,Diseases of the skin and subcutaneous tissue,skin_soft_tissue,1.0,icd10_chapter_range -764,M00,(pyogenic arthritis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -765,M01,(direct infections of joint in infectious and parasitic diseases classified elsewhere),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -766,M02,(reactive arthropathies),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -767,M03,(postinfective and reactive arthropathies in diseases classified elsewhere),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -768,M05,(seropositive rheumatoid arthritis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -769,M06,(other rheumatoid arthritis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -770,M07,(psoriatic and enteropathic arthropathies),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -771,M08,(juvenile arthritis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -772,M09,(juvenile arthritis in diseases classified elsewhere),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -773,M10,(gout),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -774,M11,(other crystal arthropathies),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -775,M12,(other specific arthropathies),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -776,M13,(other arthritis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -777,M14,(arthropathies in other diseases classified elsewhere),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -778,M15,(polyarthrosis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -779,M16,(coxarthrosis [arthrosis of hip]),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -780,M17,(gonarthrosis [arthrosis of knee]),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -781,M18,(arthrosis of first carpometacarpal joint),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -782,M19,(other arthrosis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -783,M20,(acquired deformities of fingers and toes),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -784,M21,(other acquired deformities of limbs),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -785,M22,(disorders of patella),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -786,M23,(internal derangement of knee),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -787,M24,(other specific joint derangements),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -788,M25,"(other joint disorders, not elsewhere classified)",XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -789,M30,(polyarteritis nodosa and related conditions),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -790,M31,(other necrotising vasculopathies),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -791,M32,(systemic lupus erythematosus),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -792,M33,(dermatopolymyositis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -793,M34,(systemic sclerosis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -794,M35,(other systemic involvement of connective tissue),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -795,M36,(systemic disorders of connective tissue in diseases classified elsewhere),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -796,M40,(kyphosis and lordosis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -797,M41,(scoliosis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -798,M42,(spinal osteochondrosis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -799,M43,(other deforming dorsopathies),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -800,M45,(ankylosing spondylitis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -801,M46,(other inflammatory spondylopathies),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -802,M47,(spondylosis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -803,M48,(other spondylopathies),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -804,M49,(spondylopathies in diseases classified elsewhere),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -805,M50,(cervical disk disorders),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -806,M51,(other intervertebral disk disorders),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -807,M53,"(other dorsopathies, not elsewhere classified)",XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -808,M54,(dorsalgia),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -809,M60,(myositis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -810,M61,(calcification and ossification of muscle),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -811,M62,(other disorders of muscle),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -812,M63,(disorders of muscle in diseases classified elsewhere),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -813,M65,(synovitis and tenosynovitis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -814,M66,(spontaneous rupture of synovium and tendon),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -815,M67,(other disorders of synovium and tendon),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -816,M68,(disorders of synovium and tendon in diseases classified elsewhere),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -817,M70,"(soft tissue disorders related to use, overuse and pressure)",XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -818,M71,(other bursopathies),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -819,M72,(fibroblastic disorders),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -820,M73,(soft tissue disorders in diseases classified elsewhere),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -821,M75,(shoulder lesions),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -822,M76,"(enthesopathies of lower limb, excluding foot)",XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -823,M77,(other enthesopathies),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -824,M79,"(other soft tissue disorders, not elsewhere classified)",XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -825,M80,(osteoporosis with pathological fracture),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -826,M81,(osteoporosis without pathological fracture),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -827,M82,(osteoporosis in diseases classified elsewhere),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -828,M83,(adult osteomalacia),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -829,M84,(disorders of continuity of bone),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -830,M85,(other disorders of bone density and structure),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -831,M86,(osteomyelitis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -832,M87,(osteonecrosis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -833,M88,(paget's disease of bone [osteitis deformans]),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -834,M89,(other disorders of bone),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -835,M90,(osteopathies in diseases classified elsewhere),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -836,M91,(juvenile osteochondrosis of hip and pelvis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -837,M92,(other juvenile osteochondrosis),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -838,M93,(other osteochondropathies),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -839,M94,(other disorders of cartilage),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -840,M95,(other acquired deformities of musculoskeletal system and connective tissue),XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -841,M96,"(postprocedural musculoskeletal disorders, not elsewhere classified)",XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -842,M99,"(biomechanical lesions, not elsewhere classified)",XIII,Diseases of the musculoskeletal system,musculoskeletal,1.0,icd10_chapter_range -843,N00,(acute nephritic syndrome),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -844,N01,(rapidly progressive nephritic syndrome),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -845,N02,(recurrent and persistent haematuria),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -846,N03,(chronic nephritic syndrome),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -847,N04,(nephrotic syndrome),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -848,N05,(unspecified nephritic syndrome),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -849,N06,(isolated proteinuria with specified morphological lesion),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -850,N07,"(hereditary nephropathy, not elsewhere classified)",XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -851,N08,(glomerular disorders in diseases classified elsewhere),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -852,N10,(acute tubulo-interstitial nephritis),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -853,N11,(chronic tubulo-interstitial nephritis),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -854,N12,"(tubulo-interstitial nephritis, not specified as acute or chronic)",XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -855,N13,(obstructive and reflux uropathy),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -856,N14,(drug- and heavy-metal-induced tubulo-interstitial and tubular conditions),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -857,N15,(other renal tubulo-interstitial diseases),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -858,N16,(renal tubulo-interstitial disorders in diseases classified elsewhere),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -859,N17,(acute renal failure),XIV,Diseases of the genitourinary system,kidney,1.0,icd10_chapter_range -860,N18,(chronic renal failure),XIV,Diseases of the genitourinary system,kidney,1.0,icd10_chapter_range -861,N19,(unspecified renal failure),XIV,Diseases of the genitourinary system,kidney,1.0,icd10_chapter_range -862,N20,(calculus of kidney and ureter),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -863,N21,(calculus of lower urinary tract),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -864,N22,(calculus of urinary tract in diseases classified elsewhere),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -865,N23,(unspecified renal colic),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -866,N25,(disorders resulting from impaired renal tubular function),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -867,N26,(unspecified contracted kidney),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -868,N27,(small kidney of unknown cause),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -869,N28,"(other disorders of kidney and ureter, not elsewhere classified)",XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -870,N29,(other disorders of kidney and ureter in diseases classified elsewhere),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -871,N30,(cystitis),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -872,N31,"(neuromuscular dysfunction of bladder, not elsewhere classified)",XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -873,N32,(other disorders of bladder),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -874,N33,(bladder disorders in diseases classified elsewhere),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -875,N34,(urethritis and urethral syndrome),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -876,N35,(urethral stricture),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -877,N36,(other disorders of urethra),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -878,N37,(urethral disorders in diseases classified elsewhere),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -879,N39,(other disorders of urinary system),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -880,N40,(hyperplasia of prostate),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -881,N41,(inflammatory diseases of prostate),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -882,N42,(other disorders of prostate),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -883,N43,(hydrocele and spermatocele),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -884,N44,(torsion of testis),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -885,N45,(orchitis and epididymitis),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -886,N46,(male infertility),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -887,N47,"(redundant prepuce, phimosis and paraphimosis)",XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -888,N48,(other disorders of penis),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -889,N49,"(inflammatory disorders of male genital organs, not elsewhere classified)",XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -890,N50,(other disorders of male genital organs),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -891,N51,(disorders of male genital organs in diseases classified elsewhere),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -892,N60,(benign mammary dysplasia),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -893,N61,(inflammatory disorders of breast),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -894,N62,(hypertrophy of breast),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -895,N63,(unspecified lump in breast),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -896,N64,(other disorders of breast),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -897,N70,(salpingitis and oophoritis),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -898,N71,"(inflammatory disease of uterus, except cervix)",XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -899,N72,(inflammatory disease of cervix uteri),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -900,N73,(other female pelvic inflammatory diseases),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -901,N74,(female pelvic inflammatory disorders in diseases classified elsewhere),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -902,N75,(diseases of bartholin's gland),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -903,N76,(other inflammation of vagina and vulva),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -904,N77,(vulvovaginal ulceration and inflammation in diseases classified elsewhere),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -905,N80,(endometriosis),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -906,N81,(female genital prolapse),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -907,N82,(fistulae involving female genital tract),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -908,N83,"(noninflammatory disorders of ovary, fallopian tube and broad ligament)",XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -909,N84,(polyp of female genital tract),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -910,N85,"(other noninflammatory disorders of uterus, except cervix)",XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -911,N86,(erosion and ectropion of cervix uteri),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -912,N87,(dysplasia of cervix uteri),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -913,N88,(other noninflammatory disorders of cervix uteri),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -914,N89,(other noninflammatory disorders of vagina),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -915,N90,(other noninflammatory disorders of vulva and perineum),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -916,N91,"(absent, scanty and rare menstruation)",XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -917,N92,"(excessive, frequent and irregular menstruation)",XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -918,N93,(other abnormal uterine and vaginal bleeding),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -919,N94,(pain and other conditions associated with female genital organs and menstrual cycle),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -920,N95,(menopausal and other perimenopausal disorders),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -921,N96,(habitual aborter),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -922,N97,(female infertility),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -923,N98,(complications associated with artificial fertilisation),XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -924,N99,"(postprocedural disorders of genito-urinary system, not elsewhere classified)",XIV,Diseases of the genitourinary system,genitourinary_renal,1.0,icd10_chapter_range -925,O00,(ectopic pregnancy),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -926,O01,(hydatidiform mole),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -927,O02,(other abnormal products of conception),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -928,O03,(spontaneous abortion),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -929,O04,(medical abortion),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -930,O05,(other abortion),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -931,O06,(unspecified abortion),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -932,O07,(failed attempted abortion),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -933,O08,(complications following abortion and ectopic and molar pregnancy),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -934,O10,"(pre-existing hypertension complicating pregnancy, childbirth and the puerperium)",XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -935,O11,(pre-existing hypertensive disorder with superimposed proteinuria),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -936,O12,(gestational [pregnancy-induced] oedema and proteinuria without hypertension),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -937,O13,(gestational [pregnancy-induced] hypertension without significant proteinuria),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -938,O14,(gestational [pregnancy-induced] hypertension with significant proteinuria),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -939,O15,(eclampsia),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -940,O16,(unspecified maternal hypertension),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -941,O20,(haemorrhage in early pregnancy),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -942,O21,(excessive vomiting in pregnancy),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -943,O22,(venous complications in pregnancy),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -944,O23,(infections of genito-urinary tract in pregnancy),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -945,O24,(diabetes mellitus in pregnancy),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -946,O25,(malnutrition in pregnancy),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -947,O26,(maternal care for other conditions predominantly related to pregnancy),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -948,O28,(abnormal findings on antenatal screening of mother),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -949,O29,(complications of anaesthesia during pregnancy),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -950,O30,(multiple gestation),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -951,O31,(complications specific to multiple gestation),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -952,O32,(maternal care for known or suspected malpresentation of foetus),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -953,O33,(maternal care for known or suspected disproportion),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -954,O34,(maternal care for known or suspected abnormality of pelvic organs),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -955,O35,(maternal care for known or suspected foetal abnormality and damage),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -956,O36,(maternal care for other known or suspected foetal problems),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -957,O40,(polyhydramnios),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -958,O41,(other disorders of amniotic fluid and membranes),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -959,O42,(premature rupture of membranes),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -960,O43,(placental disorders),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -961,O44,(placenta praevia),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -962,O45,(premature separation of placenta [abruptio placentae]),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -963,O46,"(antepartum haemorrhage, not elsewhere classified)",XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -964,O47,(false labour),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -965,O48,(prolonged pregnancy),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -966,O60,(preterm delivery),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -967,O61,(failed induction of labour),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -968,O62,(abnormalities of forces of labour),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -969,O63,(long labour),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -970,O64,(obstructed labour due to malposition and malpresentation of foetus),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -971,O65,(obstructed labour due to maternal pelvic abnormality),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -972,O66,(other obstructed labour),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -973,O67,"(labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified)",XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -974,O68,(labour and delivery complicated by foetal stress [distress]),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -975,O69,(labour and delivery complicated by umbilical cord complications),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -976,O70,(perineal laceration during delivery),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -977,O71,(other obstetric trauma),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -978,O72,(postpartum haemorrhage),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -979,O73,"(retained placenta and membranes, without haemorrhage)",XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -980,O74,(complications of anaesthesia during labour and delivery),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -981,O75,"(other complications of labour and delivery, not elsewhere classified)",XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -982,O80,(single spontaneous delivery),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -983,O81,(single delivery by forceps and vacuum extractor),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -984,O82,(single delivery by caesarean section),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -985,O83,(other assisted single delivery),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -986,O84,(multiple delivery),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -987,O85,(puerperal sepsis),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -988,O86,(other puerperal infections),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -989,O87,(venous complications in the puerperium),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -990,O88,(obstetric embolism),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -991,O89,(complications of anaesthesia during the puerperium),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -992,O90,"(complications of the puerperium, not elsewhere classified)",XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -993,O91,(infections of breast associated with childbirth),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -994,O92,(other disorders of breast and lactation associated with childbirth),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -995,O94,"(sequelae of complication of pregnancy, childbirth and the puerperium)",XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -996,O96,(death from any obstetric cause occurring more than 42 days but less than one year after delivery),XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -997,O98,"(maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium)",XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -998,O99,"(other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium)",XV,"Pregnancy, childbirth and puerperium",pregnancy_reproductive,1.0,icd10_chapter_range -999,P00,(foetus and newborn affected by maternal conditions that may be unrelated to present pregnancy),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1000,P02,"(foetus and newborn affected by complications of placenta, cord and membranes)",XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1001,P03,(foetus and newborn affected by other complications of labour and delivery),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1002,P04,(foetus and newborn affected by noxious influences transmitted via placenta or breast milk),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1003,P05,(slow foetal growth and foetal malnutrition),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1004,P07,"(disorders related to short gestation and low birth weight, not elsewhere classified)",XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1005,P08,(disorders related to long gestation and high birth weight),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1006,P10,(intracranial laceration and haemorrhage due to birth injury),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1007,P11,(other birth injuries to central nervous system),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1008,P12,(birth injury to scalp),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1009,P13,(birth injury to skeleton),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1010,P14,(birth injury to peripheral nervous system),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1011,P15,(other birth injuries),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1012,P20,(intra-uterine hypoxia),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1013,P21,(birth asphyxia),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1014,P22,(respiratory distress of newborn),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1015,P23,(congenital pneumonia),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1016,P24,(neonatal aspiration syndromes),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1017,P25,(interstitial emphysema and related conditions originating in the perinatal period),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1018,P26,(pulmonary haemorrhage originating in the perinatal period),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1019,P27,(chronic respiratory disease originating in the perinatal period),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1020,P28,(other respiratory conditions originating in the perinatal period),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1021,P29,(cardiovascular disorders originating in the perinatal period),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1022,P35,(congenital viral diseases),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1023,P36,(bacterial sepsis of newborn),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1024,P37,(other congenital infectious and parasitic diseases),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1025,P38,(omphalitis of newborn with or without mild haemorrhage),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1026,P39,(other infections specific to the perinatal period),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1027,P50,(foetal blood loss),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1028,P51,(umbilical haemorrhage of newborn),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1029,P52,(intracranial nontraumatic haemorrhage of foetus and newborn),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1030,P53,(haemorrhagic disease of foetus and newborn),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1031,P54,(other neonatal haemorrhages),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1032,P55,(haemolytic disease of foetus and newborn),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1033,P58,(neonatal jaundice due to other excessive haemolysis),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1034,P59,(neonatal jaundice from other and unspecified causes),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1035,P61,(other perinatal haematological disorders),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1036,P70,(transitory disorders of carbohydrate metabolism specific to foetus and newborn),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1037,P71,(transitory neonatal disorders of calcium and magnesium metabolism),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1038,P78,(other perinatal digestive system disorders),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1039,P83,(other conditions of integument specific to foetus and newborn),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1040,P91,(other disturbances of cerebral status of newborn),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1041,P92,(feeding problems of newborn),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1042,P94,(disorders of muscle tone of newborn),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1043,P95,(foetal death of unspecified cause),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1044,P96,(other conditions originating in the perinatal period),XVI,Certain conditions originating in the perinatal period,perinatal,1.0,icd10_chapter_range -1045,Q00,(anencephaly and similar malformations),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1046,Q01,(encephalocele),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1047,Q02,(microcephaly),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1048,Q03,(congenital hydrocephalus),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1049,Q04,(other congenital malformations of brain),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1050,Q05,(spina bifida),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1051,Q06,(other congenital malformations of spinal cord),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1052,Q07,(other congenital malformations of nervous system),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1053,Q10,"(congenital malformations of eyelid, lachrymal apparatus and orbit)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1054,Q11,"(anophthalmos, microphthalmos and macrophthalmos)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1055,Q12,(congenital lens malformations),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1056,Q13,(congenital malformations of anterior segment of eye),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1057,Q14,(congenital malformations of posterior segment of eye),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1058,Q15,(other congenital malformations of eye),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1059,Q16,(congenital malformations of ear causing impairment of hearing),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1060,Q17,(other congenital malformations of ear),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1061,Q18,(other congenital malformations of face and neck),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1062,Q20,(congenital malformations of cardiac chambers and connexions),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1063,Q21,(congenital malformations of cardiac septa),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1064,Q22,(congenital malformations of pulmonary and tricuspid valves),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1065,Q23,(congenital malformations of aortic and mitral valves),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1066,Q24,(other congenital malformations of heart),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1067,Q25,(congenital malformations of great arteries),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1068,Q26,(congenital malformations of great veins),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1069,Q27,(other congenital malformations of peripheral vascular system),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1070,Q28,(other congenital malformations of circulatory system),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1071,Q30,(congenital malformations of nose),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1072,Q31,(congenital malformations of larynx),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1073,Q32,(congenital malformations of trachea and bronchus),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1074,Q33,(congenital malformations of lung),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1075,Q34,(other congenital malformations of respiratory system),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1076,Q35,(cleft palate),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1077,Q36,(cleft lip),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1078,Q37,(cleft palate with cleft lip),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1079,Q38,"(other congenital malformations of tongue, mouth and pharynx)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1080,Q39,(congenital malformations of oesophagus),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1081,Q40,(other congenital malformations of upper alimentary tract),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1082,Q41,"(congenital absence, atresia and stenosis of small intestine)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1083,Q42,"(congenital absence, atresia and stenosis of large intestine)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1084,Q43,(other congenital malformations of intestine),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1085,Q44,"(congenital malformations of gallbladder, bile ducts and liver)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1086,Q45,(other congenital malformations of digestive system),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1087,Q50,"(congenital malformations of ovaries, fallopian tubes and broad ligaments)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1088,Q51,(congenital malformations of uterus and cervix),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1089,Q52,(other congenital malformations of female genitalia),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1090,Q53,(undescended testicle),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1091,Q54,(hypospadias),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1092,Q55,(other congenital malformations of male genital organs),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1093,Q56,(indeterminate sex and pseudohermaphroditism),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1094,Q60,(renal agenesis and other reduction defects of kidney),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1095,Q61,(cystic kidney disease),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1096,Q62,(congenital obstructive defects of renal pelvis and congenital malformations of ureter),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1097,Q63,(other congenital malformations of kidney),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1098,Q64,(other congenital malformations of urinary system),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1099,Q65,(congenital deformities of hip),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1100,Q66,(congenital deformities of feet),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1101,Q67,"(congenital musculoskeletal deformities of head, face, spine and chest)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1102,Q68,(other congenital musculoskeletal deformities),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1103,Q69,(polydactyly),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1104,Q70,(syndactyly),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1105,Q71,(reduction defects of upper limb),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1106,Q72,(reduction defects of lower limb),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1107,Q73,(reduction defects of unspecified limb),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1108,Q74,(other congenital malformations of limb(s)),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1109,Q75,(other congenital malformations of skull and face bones),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1110,Q76,(congenital malformations of spine and bony thorax),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1111,Q77,(osteochondrodysplasia with defects of growth of tubular bones and spine),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1112,Q78,(other osteochondrodysplasias),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1113,Q79,"(congenital malformations of musculoskeletal system, not elsewhere classified)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1114,Q80,(congenital ichthyosis),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1115,Q81,(epidermolysis bullosa),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1116,Q82,(other congenital malformations of skin),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1117,Q83,(congenital malformations of breast),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1118,Q84,(other congenital malformations of integument),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1119,Q85,"(phakomatoses, not elsewhere classified)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1120,Q86,"(congenital malformation syndromes due to known exogenous causes, not elsewhere classified)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1121,Q87,(other specified congenital malformation syndromes affecting multiple systems),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1122,Q89,"(other congenital malformations, not elsewhere classified)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1123,Q90,(down's syndrome),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1124,Q91,(edwards' syndrome and patau's syndrome),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1125,Q92,"(other trisomies and partial trisomies of the autosomes, not elsewhere classified)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1126,Q93,"(monosomies and deletions from the autosomes, not elsewhere classified)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1127,Q95,"(balanced rearrangements and structural markers, not elsewhere classified)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1128,Q96,(turner's syndrome),XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1129,Q97,"(other sex chromosome abnormalities, female phenotype, not elsewhere classified)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1130,Q98,"(other sex chromosome abnormalities, male phenotype, not elsewhere classified)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1131,Q99,"(other chromosome abnormalities, not elsewhere classified)",XVII,Congenital malformations,congenital,1.0,icd10_chapter_range -1132,CXX,Unknown Cancer,,,unmapped,0.0,icd10_chapter_range -1133,C00,Malignant neoplasm of lip,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1134,C01,Malignant neoplasm of base of tongue,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1135,C02,Malignant neoplasm of other and unspecified parts of tongue,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1136,C03,Malignant neoplasm of gum,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1137,C04,Malignant neoplasm of floor of mouth,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1138,C05,Malignant neoplasm of palate,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1139,C06,Malignant neoplasm of other and unspecified parts of mouth,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1140,C07,Malignant neoplasm of parotid gland,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1141,C08,Malignant neoplasm of other and unspecified major salivary glands,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1142,C09,Malignant neoplasm of tonsil,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1143,C10,Malignant neoplasm of oropharynx,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1144,C11,Malignant neoplasm of nasopharynx,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1145,C12,Malignant neoplasm of pyriform sinus,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1146,C13,Malignant neoplasm of hypopharynx,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1147,C14,"Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx",II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1148,C15,Malignant neoplasm of oesophagus,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1149,C16,Malignant neoplasm of stomach,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1150,C17,Malignant neoplasm of small intestine,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1151,C18,Malignant neoplasm of colon,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1152,C19,Malignant neoplasm of rectosigmoid junction,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1153,C20,Malignant neoplasm of rectum,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1154,C21,Malignant neoplasm of anus and anal canal,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1155,C22,Malignant neoplasm of liver and intrahepatic bile ducts,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1156,C23,Malignant neoplasm of gallbladder,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1157,C24,Malignant neoplasm of other and unspecified parts of biliary tract,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1158,C25,Malignant neoplasm of pancreas,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1159,C26,Malignant neoplasm of other and ill-defined digestive organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1160,C30,Malignant neoplasm of nasal cavity and middle ear,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1161,C31,Malignant neoplasm of accessory sinuses,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1162,C32,Malignant neoplasm of larynx,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1163,C33,Malignant neoplasm of trachea,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1164,C34,Malignant neoplasm of bronchus and lung,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1165,C37,Malignant neoplasm of thymus,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1166,C38,"Malignant neoplasm of heart, mediastinum and pleura",II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1167,C39,Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1168,C40,Malignant neoplasm of bone and articular cartilage of limbs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1169,C41,Malignant neoplasm of bone and articular cartilage of other and unspecified sites,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1170,C42,hematopoietic and reticuloendothelial systems (ICD-O-3 specific),II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1171,C43,Malignant melanoma of skin,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1172,C44,Other malignant neoplasms of skin,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1173,C45,Mesothelioma,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1174,C46,Kaposi's sarcoma,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1175,C47,Malignant neoplasm of peripheral nerves and autonomic nervous system,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1176,C48,Malignant neoplasm of retroperitoneum and peritoneum,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1177,C49,Malignant neoplasm of other connective and soft tissue,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1178,C50,Malignant neoplasm of breast,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1179,C51,Malignant neoplasm of vulva,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1180,C52,Malignant neoplasm of vagina,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1181,C53,Malignant neoplasm of cervix uteri,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1182,C54,Malignant neoplasm of corpus uteri,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1183,C55,"Malignant neoplasm of uterus, part unspecified",II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1184,C56,Malignant neoplasm of ovary,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1185,C57,Malignant neoplasm of other and unspecified female genital organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1186,C58,Malignant neoplasm of placenta,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1187,C60,Malignant neoplasm of penis,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1188,C61,Malignant neoplasm of prostate,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1189,C62,Malignant neoplasm of testis,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1190,C63,Malignant neoplasm of other and unspecified male genital organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1191,C64,"Malignant neoplasm of kidney, except renal pelvis",II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1192,C65,Malignant neoplasm of renal pelvis,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1193,C66,Malignant neoplasm of ureter,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1194,C67,Malignant neoplasm of bladder,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1195,C68,Malignant neoplasm of other and unspecified urinary organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1196,C69,Malignant neoplasm of eye and adnexa,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1197,C70,Malignant neoplasm of meninges,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1198,C71,Malignant neoplasm of brain,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1199,C72,"Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system",II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1200,C73,Malignant neoplasm of thyroid gland,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1201,C74,Malignant neoplasm of adrenal gland,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1202,C75,Malignant neoplasm of other endocrine glands and related structures,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1203,C76,Malignant neoplasm of other and ill-defined sites,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1204,C77,Secondary and unspecified malignant neoplasm of lymph nodes,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1205,C78,Secondary malignant neoplasm of respiratory and digestive organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1206,C79,Secondary malignant neoplasm of other sites,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1207,C80,Malignant neoplasm without specification of site,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1208,C81,Hodgkin's disease,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1209,C82,Follicular [nodular] non-Hodgkin's lymphoma,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1210,C83,Diffuse non-Hodgkin's lymphoma,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1211,C84,Peripheral and cutaneous T-cell lymphomas,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1212,C85,Other and unspecified types of non-Hodgkin's lymphoma,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1213,C86,Other specified types of T/NK-cell lymphoma,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1214,C88,Malignant immunoproliferative diseases,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1215,C90,Multiple myeloma and malignant plasma cell neoplasms,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1216,C91,Lymphoid leukaemia,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1217,C92,Myeloid leukaemia,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1218,C93,Monocytic leukaemia,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1219,C94,Other leukaemias of specified cell type,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1220,C95,Leukaemia of unspecified cell type,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1221,C96,"Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue",II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1222,C97,Malignant neoplasms of independent (primary) multiple sites,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1223,D00,"Carcinoma in situ of oral cavity, oesophagus and stomach",II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1224,D01,Carcinoma in situ of other and unspecified digestive organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1225,D02,Carcinoma in situ of middle ear and respiratory system,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1226,D03,Melanoma in situ,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1227,D04,Carcinoma in situ of skin,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1228,D05,Carcinoma in situ of breast,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1229,D06,Carcinoma in situ of cervix uteri,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1230,D07,Carcinoma in situ of other and unspecified genital organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1231,D09,Carcinoma in situ of other and unspecified sites,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1232,D10,Benign neoplasm of mouth and pharynx,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1233,D11,Benign neoplasm of major salivary glands,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1234,D12,"Benign neoplasm of colon, rectum, anus and anal canal",II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1235,D13,Benign neoplasm of other and ill-defined parts of digestive system,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1236,D15,Benign neoplasm of other and unspecified intrathoracic organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1237,D16,Benign neoplasm of bone and articular cartilage,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1238,D18,"Haemangioma and lymphangioma, any site",II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1239,D27,Benign neoplasm of ovary,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1240,D30,Benign neoplasm of urinary organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1241,D32,Benign neoplasm of meninges,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1242,D33,Benign neoplasm of brain and other parts of central nervous system,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1243,D34,Benign neoplasm of thyroid gland,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1244,D35,Benign neoplasm of other and unspecified endocrine glands,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1245,D36,Benign neoplasm of other and unspecified sites,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1246,D37,Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1247,D38,Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1248,D39,Neoplasm of uncertain or unknown behaviour of female genital organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1249,D40,Neoplasm of uncertain or unknown behaviour of male genital organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1250,D41,Neoplasm of uncertain or unknown behaviour of urinary organs,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1251,D42,Neoplasm of uncertain or unknown behaviour of meninges,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1252,D43,Neoplasm of uncertain or unknown behaviour of brain and central nervous system,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1253,D44,Neoplasm of uncertain or unknown behaviour of endocrine glands,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1254,D45,Polycythaemia vera,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1255,D46,Myelodysplastic syndromes,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1256,D47,"Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue",II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1257,D48,Neoplasm of uncertain or unknown behaviour of other and unspecified sites,II,Neoplasms,neoplasm,1.0,icd10_chapter_range -1258,DEATH,,,,unmapped,0.0,icd10_chapter_range diff --git a/organ_involvement_label_mapping.csv b/organ_involvement_label_mapping.csv new file mode 100644 index 0000000..a35f2b9 --- /dev/null +++ b/organ_involvement_label_mapping.csv @@ -0,0 +1,1257 @@ +token_id,label_code,label_name,organ_id,organ_label,organ_weight,match_source,mapping_source +3,A00,(cholera),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +4,A01,(typhoid and paratyphoid fevers),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +5,A02,(other salmonella infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +6,A03,(shigellosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +7,A04,(other bacterial intestinal infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +8,A05,(other bacterial foodborne intoxications),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +9,A06,(amoebiasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +10,A07,(other protozoal intestinal diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +11,A08,(viral and other specified intestinal infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +12,A09,(diarrhoea and gastro-enteritis of presumed infectious origin),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +13,A15,"(respiratory tuberculosis, bacteriologically and histologically confirmed)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +14,A16,"(respiratory tuberculosis, not confirmed bacteriologically or histologically)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +15,A17,(tuberculosis of nervous system),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +16,A18,(tuberculosis of other organs),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +17,A19,(miliary tuberculosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +18,A20,(plague),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +19,A22,(anthrax),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +20,A23,(brucellosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +21,A24,(glanders and melioidosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +22,A25,(rat-bite fevers),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +23,A26,(erysipeloid),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +24,A27,(leptospirosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +25,A28,"(other zoonotic bacterial diseases, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +26,A30,(leprosy [hansen's disease]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +27,A31,(infection due to other mycobacteria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +28,A32,(listeriosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +29,A33,(tetanus neonatorum),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +30,A35,(other tetanus),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +31,A36,(diphtheria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +32,A37,(whooping cough),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +33,A38,(scarlet fever),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +34,A39,(meningococcal infection),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +35,A40,(streptococcal septicaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +36,A41,(other septicaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +37,A42,(actinomycosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +38,A43,(nocardiosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +39,A44,(bartonellosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +40,A46,(erysipelas),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +41,A48,"(other bacterial diseases, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +42,A49,(bacterial infection of unspecified site),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +43,A50,(congenital syphilis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +44,A51,(early syphilis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +45,A52,(late syphilis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +46,A53,(other and unspecified syphilis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +47,A54,(gonococcal infection),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +48,A55,(chlamydial lymphogranuloma (venereum)),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +49,A56,(other sexually transmitted chlamydial diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +50,A58,(granuloma inguinale),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +51,A59,(trichomoniasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +52,A60,(anogenital herpesviral [herpes simplex] infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +53,A63,"(other predominantly sexually transmitted diseases, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +54,A64,(unspecified sexually transmitted disease),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +55,A66,(yaws),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +56,A67,(pinta [carate]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +57,A68,(relapsing fevers),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +58,A69,(other spirochaetal infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +59,A70,(chlamydia psittaci infection),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +60,A71,(trachoma),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +61,A74,(other diseases caused by chlamydiae),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +62,A75,(typhus fever),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +63,A77,(spotted fever [tick-borne rickettsioses]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +64,A78,(q fever),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +65,A79,(other rickettsioses),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +66,A80,(acute poliomyelitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +67,A81,(atypical virus infections of central nervous system),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +68,A82,(rabies),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +69,A83,(mosquito-borne viral encephalitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +70,A84,(tick-borne viral encephalitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +71,A85,"(other viral encephalitis, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +72,A86,(unspecified viral encephalitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +73,A87,(viral meningitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +74,A88,"(other viral infections of central nervous system, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +75,A89,(unspecified viral infection of central nervous system),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +76,A90,(dengue fever [classical dengue]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +77,A91,(dengue haemorrhagic fever),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +78,A92,(other mosquito-borne viral fevers),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +79,A93,"(other arthropod-borne viral fevers, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +80,A94,(unspecified arthropod-borne viral fever),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +81,A95,(yellow fever),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +82,A97,(dengue),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +83,A98,"(other viral haemorrhagic fevers, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +84,B00,(herpesviral [herpes simplex] infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +85,B01,(varicella [chickenpox]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +86,B02,(zoster [herpes zoster]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +87,B03,(smallpox),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +88,B05,(measles),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +89,B06,(rubella [german measles]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +90,B07,(viral warts),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +91,B08,"(other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +92,B09,(unspecified viral infection characterised by skin and mucous membrane lesions),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +93,B15,(acute hepatitis a),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +94,B16,(acute hepatitis b),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +95,B17,(other acute viral hepatitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +96,B18,(chronic viral hepatitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +97,B19,(unspecified viral hepatitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +98,B20,(human immunodeficiency virus [hiv] disease resulting in infectious and parasitic diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +99,B21,(human immunodeficiency virus [hiv] disease resulting in malignant neoplasms),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +100,B22,(human immunodeficiency virus [hiv] disease resulting in other specified diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +101,B23,(human immunodeficiency virus [hiv] disease resulting in other conditions),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +102,B24,(unspecified human immunodeficiency virus [hiv] disease),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +103,B25,(cytomegaloviral disease),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +104,B26,(mumps),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +105,B27,(infectious mononucleosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +106,B30,(viral conjunctivitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +107,B33,"(other viral diseases, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +108,B34,(viral infection of unspecified site),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +109,B35,(dermatophytosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +110,B36,(other superficial mycoses),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +111,B37,(candidiasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +112,B38,(coccidioidomycosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +113,B39,(histoplasmosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +114,B40,(blastomycosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +115,B42,(sporotrichosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +116,B43,(chromomycosis and phaeomycotic abscess),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +117,B44,(aspergillosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +118,B45,(cryptococcosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +119,B46,(zygomycosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +120,B47,(mycetoma),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +121,B48,"(other mycoses, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +122,B49,(unspecified mycosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +123,B50,(plasmodium falciparum malaria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +124,B51,(plasmodium vivax malaria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +125,B52,(plasmodium malariae malaria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +126,B53,(other parasitologically confirmed malaria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +127,B54,(unspecified malaria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +128,B55,(leishmaniasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +129,B57,(chagas' disease),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +130,B58,(toxoplasmosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +131,B59,(pneumocystosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +132,B60,"(other protozoal diseases, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +133,B65,(schistosomiasis [bilharziasis]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +134,B66,(other fluke infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +135,B67,(echinococcosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +136,B68,(taeniasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +137,B69,(cysticercosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +138,B71,(other cestode infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +139,B73,(onchocerciasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +140,B74,(filariasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +141,B75,(trichinellosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +142,B76,(hookworm diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +143,B77,(ascariasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +144,B78,(strongyloidiasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +145,B79,(trichuriasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +146,B80,(enterobiasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +147,B81,"(other intestinal helminthiases, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +148,B82,(unspecified intestinal parasitism),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +149,B83,(other helminthiases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +150,B85,(pediculosis and phthiriasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +151,B86,(scabies),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +152,B87,(myiasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +153,B88,(other infestations),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +154,B89,(unspecified parasitic disease),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +155,B90,(sequelae of tuberculosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +156,B91,(sequelae of poliomyelitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +157,B94,(sequelae of other and unspecified infectious and parasitic diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +158,B95,(streptococcus and staphylococcus as the cause of diseases classified to other chapters),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +159,B96,(other bacterial agents as the cause of diseases classified to other chapters),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +160,B97,(viral agents as the cause of diseases classified to other chapters),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +161,B98,(other specified infectious agents as the cause of diseases classified to other chapters),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +162,B99,(other and unspecified infectious diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +163,D50,(iron deficiency anaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +164,D51,(vitamin b12 deficiency anaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +165,D52,(folate deficiency anaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +166,D53,(other nutritional anaemias),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +167,D55,(anaemia due to enzyme disorders),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +168,D56,(thalassaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +169,D57,(sickle-cell disorders),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +170,D58,(other hereditary haemolytic anaemias),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +171,D59,(acquired haemolytic anaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +172,D60,(acquired pure red cell aplasia [erythroblastopenia]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +173,D61,(other aplastic anaemias),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +174,D62,(acute posthaemorrhagic anaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +175,D63,(anaemia in chronic diseases classified elsewhere),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +176,D64,(other anaemias),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +177,D65,(disseminated intravascular coagulation [defibrination syndrome]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +178,D66,(hereditary factor viii deficiency),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +179,D67,(hereditary factor ix deficiency),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +180,D68,(other coagulation defects),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +181,D69,(purpura and other haemorrhagic conditions),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +182,D70,(agranulocytosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +183,D71,(functional disorders of polymorphonuclear neutrophils),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +184,D72,(other disorders of white blood cells),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +185,D73,(diseases of spleen),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +186,D74,(methaemoglobinaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +187,D75,(other diseases of blood and blood-forming organs),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +188,D76,(certain diseases involving lymphoreticular tissue and reticulohistiocytic system),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +189,D77,(other disorders of blood and blood-forming organs in diseases classified elsewhere),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +190,D80,(immunodeficiency with predominantly antibody defects),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +191,D81,(combined immunodeficiencies),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +192,D82,(immunodeficiency associated with other major defects),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +193,D83,(common variable immunodeficiency),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +194,D84,(other immunodeficiencies),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +195,D86,(sarcoidosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +196,D89,"(other disorders involving the immune mechanism, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +197,E01,(iodine-deficiency-related thyroid disorders and allied conditions),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +198,E02,(subclinical iodine-deficiency hypothyroidism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +199,E03,(other hypothyroidism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +200,E04,(other non-toxic goitre),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +201,E05,(thyrotoxicosis [hyperthyroidism]),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +202,E06,(thyroiditis),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +203,E07,(other disorders of thyroid),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +204,E10,(insulin-dependent diabetes mellitus),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +205,E11,(non-insulin-dependent diabetes mellitus),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +206,E12,(malnutrition-related diabetes mellitus),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +207,E13,(other specified diabetes mellitus),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +208,E14,(unspecified diabetes mellitus),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +209,E15,(nondiabetic hypoglycaemic coma),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +210,E16,(other disorders of pancreatic internal secretion),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +211,E20,(hypoparathyroidism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +212,E21,(hyperparathyroidism and other disorders of parathyroid gland),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +213,E22,(hyperfunction of pituitary gland),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +214,E23,(hypofunction and other disorders of pituitary gland),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +215,E24,(cushing's syndrome),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +216,E25,(adrenogenital disorders),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +217,E26,(hyperaldosteronism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +218,E27,(other disorders of adrenal gland),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +219,E28,(ovarian dysfunction),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +220,E29,(testicular dysfunction),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +221,E30,"(disorders of puberty, not elsewhere classified)",adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +222,E31,(polyglandular dysfunction),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +223,E32,(diseases of thymus),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +224,E34,(other endocrine disorders),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +225,E35,(disorders of endocrine glands in diseases classified elsewhere),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +226,E41,(nutritional marasmus),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +227,E43,(unspecified severe protein-energy malnutrition),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +228,E44,(protein-energy malnutrition of moderate and mild degree),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +229,E45,(retarded development following protein-energy malnutrition),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +230,E46,(unspecified protein-energy malnutrition),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +231,E50,(vitamin a deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +232,E51,(thiamine deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +233,E52,(niacin deficiency [pellagra]),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +234,E53,(deficiency of other b group vitamins),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +235,E54,(ascorbic acid deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +236,E55,(vitamin d deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +237,E56,(other vitamin deficiencies),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +238,E58,(dietary calcium deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +239,E59,(dietary selenium deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +240,E60,(dietary zinc deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +241,E61,(deficiency of other nutrient elements),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +242,E63,(other nutritional deficiencies),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +243,E64,(sequelae of malnutrition and other nutritional deficiencies),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +244,E65,(localised adiposity),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +245,E66,(obesity),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +246,E67,(other hyperalimentation),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +247,E68,(sequelae of hyperalimentation),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +248,E70,(disorders of aromatic amino-acid metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +249,E71,(disorders of branched-chain amino-acid metabolism and fatty-acid metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +250,E72,(other disorders of amino-acid metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +251,E73,(lactose intolerance),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +252,E74,(other disorders of carbohydrate metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +253,E75,(disorders of sphingolipid metabolism and other lipid storage disorders),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +254,E76,(disorders of glycosaminoglycan metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +255,E77,(disorders of glycoprotein metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +256,E78,(disorders of lipoprotein metabolism and other lipidaemias),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +257,E79,(disorders of purine and pyrimidine metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +258,E80,(disorders of porphyrin and bilirubin metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +259,E83,(disorders of mineral metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +260,E84,(cystic fibrosis),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +261,E85,(amyloidosis),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +262,E86,(volume depletion),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +263,E87,"(other disorders of fluid, electrolyte and acid-base balance)",adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +264,E88,(other metabolic disorders),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +265,E89,"(postprocedural endocrine and metabolic disorders, not elsewhere classified)",adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +266,F00,(dementia in alzheimer's disease),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +267,F01,(vascular dementia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +268,F02,(dementia in other diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +269,F03,(unspecified dementia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +270,F04,"(organic amnesic syndrome, not induced by alcohol and other psychoactive substances)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +271,F05,"(delirium, not induced by alcohol and other psychoactive substances)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +272,F06,(other mental disorders due to brain damage and dysfunction and to physical disease),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +273,F07,"(personality and behavioural disorders due to brain disease, damage and dysfunction)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +274,F09,(unspecified organic or symptomatic mental disorder),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +275,F10,(mental and behavioural disorders due to use of alcohol),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +276,F11,(mental and behavioural disorders due to use of opioids),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +277,F12,(mental and behavioural disorders due to use of cannabinoids),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +278,F13,(mental and behavioural disorders due to use of sedatives or hypnotics),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +279,F14,(mental and behavioural disorders due to use of cocaine),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +280,F15,"(mental and behavioural disorders due to use of other stimulants, including caffeine)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +281,F16,(mental and behavioural disorders due to use of hallucinogens),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +282,F17,(mental and behavioural disorders due to use of tobacco),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +283,F18,(mental and behavioural disorders due to use of volatile solvents),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +284,F19,(mental and behavioural disorders due to multiple drug use and use of other psychoactive substances),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +285,F20,(schizophrenia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +286,F21,(schizotypal disorder),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +287,F22,(persistent delusional disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +288,F23,(acute and transient psychotic disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +289,F24,(induced delusional disorder),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +290,F25,(schizoaffective disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +291,F28,(other nonorganic psychotic disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +292,F29,(unspecified nonorganic psychosis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +293,F30,(manic episode),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +294,F31,(bipolar affective disorder),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +295,F32,(depressive episode),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +296,F33,(recurrent depressive disorder),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +297,F34,(persistent mood [affective] disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +298,F38,(other mood [affective] disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +299,F39,(unspecified mood [affective] disorder),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +300,F40,(phobic anxiety disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +301,F41,(other anxiety disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +302,F42,(obsessive-compulsive disorder),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +303,F43,"(reaction to severe stress, and adjustment disorders)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +304,F44,(dissociative [conversion] disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +305,F45,(somatoform disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +306,F48,(other neurotic disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +307,F50,(eating disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +308,F51,(nonorganic sleep disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +309,F52,"(sexual dysfunction, not caused by organic disorder or disease)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +310,F53,"(mental and behavioural disorders associated with the puerperium, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +311,F54,(psychological and behavioural factors associated with disorders or diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +312,F55,(abuse of non-dependence-producing substances),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +313,F59,(unspecified behavioural syndromes associated with physiological disturbances and physical factors),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +314,F60,(specific personality disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +315,F61,(mixed and other personality disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +316,F62,"(enduring personality changes, not attributable to brain damage and disease)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +317,F63,(habit and impulse disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +318,F64,(gender identity disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +319,F65,(disorders of sexual preference),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +320,F66,(psychological and behavioural disorders associated with sexual development and orientation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +321,F68,(other disorders of adult personality and behaviour),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +322,F69,(unspecified disorder of adult personality and behaviour),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +323,F70,(mild mental retardation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +324,F71,(moderate mental retardation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +325,F72,(severe mental retardation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +326,F78,(other mental retardation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +327,F79,(unspecified mental retardation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +328,F80,(specific developmental disorders of speech and language),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +329,F81,(specific developmental disorders of scholastic skills),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +330,F82,(specific developmental disorder of motor function),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +331,F83,(mixed specific developmental disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +332,F84,(pervasive developmental disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +333,F88,(other disorders of psychological development),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +334,F89,(unspecified disorder of psychological development),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +335,F90,(hyperkinetic disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +336,F91,(conduct disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +337,F92,(mixed disorders of conduct and emotions),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +338,F93,(emotional disorders with onset specific to childhood),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +339,F94,(disorders of social functioning with onset specific to childhood and adolescence),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +340,F95,(tic disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +341,F98,(other behavioural and emotional disorders with onset usually occurring in childhood and adolescence),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +342,F99,"(mental disorder, not otherwise specified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +343,G00,"(bacterial meningitis, not elsewhere classified)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +344,G01,(meningitis in bacterial diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +345,G02,(meningitis in other infectious and parasitic diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +346,G03,(meningitis due to other and unspecified causes),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +347,G04,"(encephalitis, myelitis and encephalomyelitis)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +348,G05,"(encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +349,G06,(intracranial and intraspinal abscess and granuloma),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +350,G07,(intracranial and intraspinal abscess and granuloma in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +351,G08,(intracranial and intraspinal phlebitis and thrombophlebitis),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +352,G09,(sequelae of inflammatory diseases of central nervous system),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +353,G10,(huntington's disease),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +354,G11,(hereditary ataxia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +355,G12,(spinal muscular atrophy and related syndromes),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +356,G13,(systemic atrophies primarily affecting central nervous system in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +357,G14,(postpolio syndrome),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +358,G20,(parkinson's disease),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +359,G21,(secondary parkinsonism),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +360,G22,(parkinsonism in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +361,G23,(other degenerative diseases of basal ganglia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +362,G24,(dystonia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +363,G25,(other extrapyramidal and movement disorders),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +364,G30,(alzheimer's disease),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +365,G31,"(other degenerative diseases of nervous system, not elsewhere classified)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +366,G32,(other degenerative disorders of nervous system in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +367,G35,(multiple sclerosis),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +368,G36,(other acute disseminated demyelination),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +369,G37,(other demyelinating diseases of central nervous system),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +370,G40,(epilepsy),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +371,G41,(status epilepticus),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +372,G43,(migraine),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +373,G44,(other headache syndromes),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +374,G45,(transient cerebral ischaemic attacks and related syndromes),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +375,G46,(vascular syndromes of brain in cerebrovascular diseases),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +376,G47,(sleep disorders),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +377,G50,(disorders of trigeminal nerve),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +378,G51,(facial nerve disorders),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +379,G52,(disorders of other cranial nerves),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +380,G53,(cranial nerve disorders in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +381,G54,(nerve root and plexus disorders),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +382,G55,(nerve root and plexus compressions in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +383,G56,(mononeuropathies of upper limb),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +384,G57,(mononeuropathies of lower limb),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +385,G58,(other mononeuropathies),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +386,G59,(mononeuropathy in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +387,G60,(hereditary and idiopathic neuropathy),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +388,G61,(inflammatory polyneuropathy),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +389,G62,(other polyneuropathies),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +390,G63,(polyneuropathy in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +391,G64,(other disorders of peripheral nervous system),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +392,G70,(myasthenia gravis and other myoneural disorders),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +393,G71,(primary disorders of muscles),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +394,G72,(other myopathies),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +395,G73,(disorders of myoneural junction and muscle in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +396,G80,(infantile cerebral palsy),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +397,G81,(hemiplegia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +398,G82,(paraplegia and tetraplegia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +399,G83,(other paralytic syndromes),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +400,G90,(disorders of autonomic nervous system),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +401,G91,(hydrocephalus),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +402,G92,(toxic encephalopathy),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +403,G93,(other disorders of brain),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +404,G94,(other disorders of brain in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +405,G95,(other diseases of spinal cord),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +406,G96,(other disorders of central nervous system),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +407,G97,"(postprocedural disorders of nervous system, not elsewhere classified)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +408,G98,"(other disorders of nervous system, not elsewhere classified)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +409,G99,(other disorders of nervous system in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +410,H00,(hordeolum and chalazion),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +411,H01,(other inflammation of eyelid),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +412,H02,(other disorders of eyelid),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +413,H03,(disorders of eyelid in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +414,H04,(disorders of lachrymal system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +415,H05,(disorders of orbit),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +416,H06,(disorders of lachrymal system and orbit in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +417,H10,(conjunctivitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +418,H11,(other disorders of conjunctiva),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +419,H13,(disorders of conjunctiva in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +420,H15,(disorders of sclera),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +421,H16,(keratitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +422,H17,(corneal scars and opacities),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +423,H18,(other disorders of cornea),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +424,H19,(disorders of sclera and cornea in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +425,H20,(iridocyclitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +426,H21,(other disorders of iris and ciliary body),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +427,H22,(disorders of iris and ciliary body in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +428,H25,(senile cataract),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +429,H26,(other cataract),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +430,H27,(other disorders of lens),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +431,H28,(cataract and other disorders of lens in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +432,H30,(chorioretinal inflammation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +433,H31,(other disorders of choroid),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +434,H32,(chorioretinal disorders in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +435,H33,(retinal detachments and breaks),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +436,H34,(retinal vascular occlusions),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +437,H35,(other retinal disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +438,H36,(retinal disorders in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +439,H40,(glaucoma),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +440,H42,(glaucoma in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +441,H43,(disorders of vitreous body),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +442,H44,(disorders of globe),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +443,H45,(disorders of vitreous body and globe in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +444,H46,(optic neuritis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +445,H47,(other disorders of optic [2nd] nerve and visual pathways),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +446,H48,(disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +447,H49,(paralytic strabismus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +448,H50,(other strabismus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +449,H51,(other disorders of binocular movement),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +450,H52,(disorders of refraction and accommodation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +451,H53,(visual disturbances),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +452,H54,(blindness and low vision),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +453,H55,(nystagmus and other irregular eye movements),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +454,H57,(other disorders of eye and adnexa),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +455,H58,(other disorders of eye and adnexa in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +456,H59,"(postprocedural disorders of eye and adnexa, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +457,H60,(otitis externa),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +458,H61,(other disorders of external ear),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +459,H62,(disorders of external ear in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +460,H65,(nonsuppurative otitis media),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +461,H66,(suppurative and unspecified otitis media),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +462,H67,(otitis media in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +463,H68,(eustachian salpingitis and obstruction),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +464,H69,(other disorders of eustachian tube),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +465,H70,(mastoiditis and related conditions),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +466,H71,(cholesteatoma of middle ear),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +467,H72,(perforation of tympanic membrane),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +468,H73,(other disorders of tympanic membrane),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +469,H74,(other disorders of middle ear and mastoid),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +470,H75,(other disorders of middle ear and mastoid in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +471,H80,(otosclerosis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +472,H81,(disorders of vestibular function),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +473,H82,(vertiginous syndromes in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +474,H83,(other diseases of inner ear),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +475,H90,(conductive and sensorineural hearing loss),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +476,H91,(other hearing loss),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +477,H92,(otalgia and effusion of ear),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +478,H93,"(other disorders of ear, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +479,H94,(other disorders of ear in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +480,H95,"(postprocedural disorders of ear and mastoid process, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +481,I00,(rheumatic fever without mention of heart involvement),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +482,I01,(rheumatic fever with heart involvement),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +483,I02,(rheumatic chorea),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +484,I05,(rheumatic mitral valve diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +485,I06,(rheumatic aortic valve diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +486,I07,(rheumatic tricuspid valve diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +487,I08,(multiple valve diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +488,I09,(other rheumatic heart diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +489,I10,(essential (primary) hypertension),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +490,I11,(hypertensive heart disease),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +491,I12,(hypertensive renal disease),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +492,I13,(hypertensive heart and renal disease),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +493,I15,(secondary hypertension),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +494,I20,(angina pectoris),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +495,I21,(acute myocardial infarction),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +496,I22,(subsequent myocardial infarction),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +497,I23,(certain current complications following acute myocardial infarction),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +498,I24,(other acute ischaemic heart diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +499,I25,(chronic ischaemic heart disease),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +500,I26,(pulmonary embolism),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +501,I27,(other pulmonary heart diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +502,I28,(other diseases of pulmonary vessels),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +503,I30,(acute pericarditis),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +504,I31,(other diseases of pericardium),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +505,I32,(pericarditis in diseases classified elsewhere),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +506,I33,(acute and subacute endocarditis),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +507,I34,(nonrheumatic mitral valve disorders),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +508,I35,(nonrheumatic aortic valve disorders),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +509,I36,(nonrheumatic tricuspid valve disorders),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +510,I37,(pulmonary valve disorders),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +511,I38,"(endocarditis, valve unspecified)",heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +512,I39,(endocarditis and heart valve disorders in diseases classified elsewhere),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +513,I40,(acute myocarditis),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +514,I41,(myocarditis in diseases classified elsewhere),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +515,I42,(cardiomyopathy),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +516,I43,(cardiomyopathy in diseases classified elsewhere),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +517,I44,(atrioventricular and left bundle-branch block),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +518,I45,(other conduction disorders),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +519,I46,(cardiac arrest),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +520,I47,(paroxysmal tachycardia),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +521,I48,(atrial fibrillation and flutter),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +522,I49,(other cardiac arrhythmias),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +523,I50,(heart failure),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +524,I51,(complications and ill-defined descriptions of heart disease),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +525,I52,(other heart disorders in diseases classified elsewhere),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +526,I60,(subarachnoid haemorrhage),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +527,I61,(intracerebral haemorrhage),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +528,I62,(other nontraumatic intracranial haemorrhage),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +529,I63,(cerebral infarction),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +530,I64,"(stroke, not specified as haemorrhage or infarction)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +531,I65,"(occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +532,I66,"(occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +533,I67,(other cerebrovascular diseases),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +534,I68,(cerebrovascular disorders in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +535,I69,(sequelae of cerebrovascular disease),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +536,I70,(atherosclerosis),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +537,I71,(aortic aneurysm and dissection),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +538,I72,(other aneurysm),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +539,I73,(other peripheral vascular diseases),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +540,I74,(arterial embolism and thrombosis),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +541,I77,(other disorders of arteries and arterioles),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +542,I78,(diseases of capillaries),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +543,I79,"(disorders of arteries, arterioles and capillaries in diseases classified elsewhere)",artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +544,I80,(phlebitis and thrombophlebitis),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +545,I81,(portal vein thrombosis),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +546,I82,(other venous embolism and thrombosis),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +547,I83,(varicose veins of lower extremities),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +548,I84,(haemorrhoids),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +549,I85,(oesophageal varices),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +550,I86,(varicose veins of other sites),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +551,I87,(other disorders of veins),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +552,I88,(nonspecific lymphadenitis),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +553,I89,(other non-infective disorders of lymphatic vessels and lymph nodes),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +554,I95,(hypotension),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +555,I97,"(postprocedural disorders of circulatory system, not elsewhere classified)",artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +556,I98,(other disorders of circulatory system in diseases classified elsewhere),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +557,I99,(other and unspecified disorders of circulatory system),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +558,J00,(acute nasopharyngitis [common cold]),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +559,J01,(acute sinusitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +560,J02,(acute pharyngitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +561,J03,(acute tonsillitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +562,J04,(acute laryngitis and tracheitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +563,J05,(acute obstructive laryngitis [croup] and epiglottitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +564,J06,(acute upper respiratory infections of multiple and unspecified sites),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +565,J09,(influenza due to certain identified influenza virus),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +566,J10,(influenza due to identified influenza virus),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +567,J11,"(influenza, virus not identified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +568,J12,"(viral pneumonia, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +569,J13,(pneumonia due to streptococcus pneumoniae),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +570,J14,(pneumonia due to haemophilus influenzae),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +571,J15,"(bacterial pneumonia, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +572,J16,"(pneumonia due to other infectious organisms, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +573,J17,(pneumonia in diseases classified elsewhere),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +574,J18,"(pneumonia, organism unspecified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +575,J20,(acute bronchitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +576,J21,(acute bronchiolitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +577,J22,(unspecified acute lower respiratory infection),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +578,J30,(vasomotor and allergic rhinitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +579,J31,"(chronic rhinitis, nasopharyngitis and pharyngitis)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +580,J32,(chronic sinusitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +581,J33,(nasal polyp),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +582,J34,(other disorders of nose and nasal sinuses),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +583,J35,(chronic diseases of tonsils and adenoids),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +584,J36,(peritonsillar abscess),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +585,J37,(chronic laryngitis and laryngotracheitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +586,J38,"(diseases of vocal cords and larynx, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +587,J39,(other diseases of upper respiratory tract),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +588,J40,"(bronchitis, not specified as acute or chronic)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +589,J41,(simple and mucopurulent chronic bronchitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +590,J42,(unspecified chronic bronchitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +591,J43,(emphysema),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +592,J44,(other chronic obstructive pulmonary disease),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +593,J45,(asthma),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +594,J46,(status asthmaticus),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +595,J47,(bronchiectasis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +596,J60,(coalworker's pneumoconiosis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +597,J61,(pneumoconiosis due to asbestos and other mineral fibres),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +598,J62,(pneumoconiosis due to dust containing silica),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +599,J63,(pneumoconiosis due to other inorganic dusts),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +600,J64,(unspecified pneumoconiosis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +601,J66,(airway disease due to specific organic dust),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +602,J67,(hypersensitivity pneumonitis due to organic dust),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +603,J68,"(respiratory conditions due to inhalation of chemicals, gases, fumes and vapours)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +604,J69,(pneumonitis due to solids and liquids),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +605,J70,(respiratory conditions due to other external agents),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +606,J80,(adult respiratory distress syndrome),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +607,J81,(pulmonary oedema),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +608,J82,"(pulmonary eosinophilia, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +609,J84,(other interstitial pulmonary diseases),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +610,J85,(abscess of lung and mediastinum),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +611,J86,(pyothorax),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +612,J90,"(pleural effusion, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +613,J91,(pleural effusion in conditions classified elsewhere),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +614,J92,(pleural plaque),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +615,J93,(pneumothorax),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +616,J94,(other pleural conditions),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +617,J95,"(postprocedural respiratory disorders, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +618,J96,"(respiratory failure, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +619,J98,(other respiratory disorders),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +620,J99,(respiratory disorders in diseases classified elsewhere),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +621,K00,(disorders of tooth development and eruption),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +622,K01,(embedded and impacted teeth),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +623,K02,(dental caries),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +624,K03,(other diseases of hard tissues of teeth),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +625,K04,(diseases of pulp and periapical tissues),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +626,K05,(gingivitis and periodontal diseases),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +627,K06,(other disorders of gingiva and edentulous alveolar ridge),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +628,K07,(dentofacial anomalies [including malocclusion]),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +629,K08,(other disorders of teeth and supporting structures),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +630,K09,"(cysts of oral region, not elsewhere classified)",intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +631,K10,(other diseases of jaws),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +632,K11,(diseases of salivary glands),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +633,K12,(stomatitis and related lesions),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +634,K13,(other diseases of lip and oral mucosa),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +635,K14,(diseases of tongue),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +636,K20,(oesophagitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +637,K21,(gastro-oesophageal reflux disease),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +638,K22,(other diseases of oesophagus),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +639,K23,(disorders of oesophagus in diseases classified elsewhere),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +640,K25,(gastric ulcer),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +641,K26,(duodenal ulcer),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +642,K27,"(peptic ulcer, site unspecified)",intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +643,K28,(gastrojejunal ulcer),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +644,K29,(gastritis and duodenitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +645,K30,(dyspepsia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +646,K31,(other diseases of stomach and duodenum),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +647,K35,(acute appendicitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +648,K36,(other appendicitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +649,K37,(unspecified appendicitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +650,K38,(other diseases of appendix),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +651,K40,(inguinal hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +652,K41,(femoral hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +653,K42,(umbilical hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +654,K43,(ventral hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +655,K44,(diaphragmatic hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +656,K45,(other abdominal hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +657,K46,(unspecified abdominal hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +658,K50,(crohn's disease [regional enteritis]),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +659,K51,(ulcerative colitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +660,K52,(other non-infective gastro-enteritis and colitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +661,K55,(vascular disorders of intestine),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +662,K56,(paralytic ileus and intestinal obstruction without hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +663,K57,(diverticular disease of intestine),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +664,K58,(irritable bowel syndrome),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +665,K59,(other functional intestinal disorders),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +666,K60,(fissure and fistula of anal and rectal regions),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +667,K61,(abscess of anal and rectal regions),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +668,K62,(other diseases of anus and rectum),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +669,K63,(other diseases of intestine),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +670,K64,(haemorrhoids and perianal venous thrombosis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +671,K65,(peritonitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +672,K66,(other disorders of peritoneum),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +673,K67,(disorders of peritoneum in infectious diseases classified elsewhere),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +674,K70,(alcoholic liver disease),liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +675,K71,(toxic liver disease),liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +676,K72,"(hepatic failure, not elsewhere classified)",liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +677,K73,"(chronic hepatitis, not elsewhere classified)",liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +678,K74,(fibrosis and cirrhosis of liver),liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +679,K75,(other inflammatory liver diseases),liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +680,K76,(other diseases of liver),liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +681,K77,(liver disorders in diseases classified elsewhere),liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +682,K80,(cholelithiasis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +683,K81,(cholecystitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +684,K82,(other diseases of gallbladder),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +685,K83,(other diseases of biliary tract),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +686,K85,(acute pancreatitis),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +687,K86,(other diseases of pancreas),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +688,K87,"(disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere)",intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +689,K90,(intestinal malabsorption),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +690,K91,"(postprocedural disorders of digestive system, not elsewhere classified)",intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +691,K92,(other diseases of digestive system),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +692,K93,(disorders of other digestive organs in diseases classified elsewhere),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +693,L00,(staphylococcal scalded skin syndrome),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +694,L01,(impetigo),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +695,L02,"(cutaneous abscess, furuncle and carbuncle)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +696,L03,(cellulitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +697,L04,(acute lymphadenitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +698,L05,(pilonidal cyst),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +699,L08,(other local infections of skin and subcutaneous tissue),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +700,L10,(pemphigus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +701,L11,(other acantholytic disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +702,L12,(pemphigoid),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +703,L13,(other bullous disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +704,L14,(bullous disorders in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +705,L20,(atopic dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +706,L21,(seborrhoeic dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +707,L22,(diaper [napkin] dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +708,L23,(allergic contact dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +709,L24,(irritant contact dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +710,L25,(unspecified contact dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +711,L26,(exfoliative dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +712,L27,(dermatitis due to substances taken internally),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +713,L28,(lichen simplex chronicus and prurigo),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +714,L29,(pruritus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +715,L30,(other dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +716,L40,(psoriasis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +717,L41,(parapsoriasis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +718,L42,(pityriasis rosea),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +719,L43,(lichen planus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +720,L44,(other papulosquamous disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +721,L50,(urticaria),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +722,L51,(erythema multiforme),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +723,L52,(erythema nodosum),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +724,L53,(other erythematous conditions),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +725,L54,(erythema in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +726,L55,(sunburn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +727,L56,(other acute skin changes due to ultraviolet radiation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +728,L57,(skin changes due to chronic exposure to nonionising radiation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +729,L58,(radiodermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +730,L59,(other disorders of skin and subcutaneous tissue related to radiation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +731,L60,(nail disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +732,L62,(nail disorders in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +733,L63,(alopecia areata),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +734,L64,(androgenic alopecia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +735,L65,(other nonscarring hair loss),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +736,L66,(cicatricial alopecia [scarring hair loss]),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +737,L67,(hair colour and hair shaft abnormalities),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +738,L68,(hypertrichosis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +739,L70,(acne),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +740,L71,(rosacea),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +741,L72,(follicular cysts of skin and subcutaneous tissue),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +742,L73,(other follicular disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +743,L74,(eccrine sweat disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +744,L75,(apocrine sweat disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +745,L80,(vitiligo),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +746,L81,(other disorders of pigmentation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +747,L82,(seborrhoeic keratosis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +748,L83,(acanthosis nigricans),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +749,L84,(corns and callosities),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +750,L85,(other epidermal thickening),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +751,L86,(keratoderma in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +752,L87,(transepidermal elimination disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +753,L88,(pyoderma gangrenosum),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +754,L89,(decubitus ulcer),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +755,L90,(atrophic disorders of skin),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +756,L91,(hypertrophic disorders of skin),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +757,L92,(granulomatous disorders of skin and subcutaneous tissue),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +758,L93,(lupus erythematosus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +759,L94,(other localised connective tissue disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +760,L95,"(vasculitis limited to skin, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +761,L97,"(ulcer of lower limb, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +762,L98,"(other disorders of skin and subcutaneous tissue, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +763,L99,(other disorders of skin and subcutaneous tissue in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +764,M00,(pyogenic arthritis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +765,M01,(direct infections of joint in infectious and parasitic diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +766,M02,(reactive arthropathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +767,M03,(postinfective and reactive arthropathies in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +768,M05,(seropositive rheumatoid arthritis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +769,M06,(other rheumatoid arthritis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +770,M07,(psoriatic and enteropathic arthropathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +771,M08,(juvenile arthritis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +772,M09,(juvenile arthritis in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +773,M10,(gout),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +774,M11,(other crystal arthropathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +775,M12,(other specific arthropathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +776,M13,(other arthritis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +777,M14,(arthropathies in other diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +778,M15,(polyarthrosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +779,M16,(coxarthrosis [arthrosis of hip]),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +780,M17,(gonarthrosis [arthrosis of knee]),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +781,M18,(arthrosis of first carpometacarpal joint),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +782,M19,(other arthrosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +783,M20,(acquired deformities of fingers and toes),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +784,M21,(other acquired deformities of limbs),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +785,M22,(disorders of patella),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +786,M23,(internal derangement of knee),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +787,M24,(other specific joint derangements),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +788,M25,"(other joint disorders, not elsewhere classified)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +789,M30,(polyarteritis nodosa and related conditions),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +790,M31,(other necrotising vasculopathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +791,M32,(systemic lupus erythematosus),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +792,M33,(dermatopolymyositis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +793,M34,(systemic sclerosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +794,M35,(other systemic involvement of connective tissue),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +795,M36,(systemic disorders of connective tissue in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +796,M40,(kyphosis and lordosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +797,M41,(scoliosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +798,M42,(spinal osteochondrosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +799,M43,(other deforming dorsopathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +800,M45,(ankylosing spondylitis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +801,M46,(other inflammatory spondylopathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +802,M47,(spondylosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +803,M48,(other spondylopathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +804,M49,(spondylopathies in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +805,M50,(cervical disk disorders),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +806,M51,(other intervertebral disk disorders),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +807,M53,"(other dorsopathies, not elsewhere classified)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +808,M54,(dorsalgia),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +809,M60,(myositis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +810,M61,(calcification and ossification of muscle),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +811,M62,(other disorders of muscle),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +812,M63,(disorders of muscle in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +813,M65,(synovitis and tenosynovitis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +814,M66,(spontaneous rupture of synovium and tendon),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +815,M67,(other disorders of synovium and tendon),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +816,M68,(disorders of synovium and tendon in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +817,M70,"(soft tissue disorders related to use, overuse and pressure)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +818,M71,(other bursopathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +819,M72,(fibroblastic disorders),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +820,M73,(soft tissue disorders in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +821,M75,(shoulder lesions),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +822,M76,"(enthesopathies of lower limb, excluding foot)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +823,M77,(other enthesopathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +824,M79,"(other soft tissue disorders, not elsewhere classified)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +825,M80,(osteoporosis with pathological fracture),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +826,M81,(osteoporosis without pathological fracture),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +827,M82,(osteoporosis in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +828,M83,(adult osteomalacia),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +829,M84,(disorders of continuity of bone),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +830,M85,(other disorders of bone density and structure),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +831,M86,(osteomyelitis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +832,M87,(osteonecrosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +833,M88,(paget's disease of bone [osteitis deformans]),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +834,M89,(other disorders of bone),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +835,M90,(osteopathies in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +836,M91,(juvenile osteochondrosis of hip and pelvis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +837,M92,(other juvenile osteochondrosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +838,M93,(other osteochondropathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +839,M94,(other disorders of cartilage),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +840,M95,(other acquired deformities of musculoskeletal system and connective tissue),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +841,M96,"(postprocedural musculoskeletal disorders, not elsewhere classified)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +842,M99,"(biomechanical lesions, not elsewhere classified)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +843,N00,(acute nephritic syndrome),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +844,N01,(rapidly progressive nephritic syndrome),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +845,N02,(recurrent and persistent haematuria),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +846,N03,(chronic nephritic syndrome),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +847,N04,(nephrotic syndrome),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +848,N05,(unspecified nephritic syndrome),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +849,N06,(isolated proteinuria with specified morphological lesion),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +850,N07,"(hereditary nephropathy, not elsewhere classified)",kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +851,N08,(glomerular disorders in diseases classified elsewhere),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +852,N10,(acute tubulo-interstitial nephritis),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +853,N11,(chronic tubulo-interstitial nephritis),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +854,N12,"(tubulo-interstitial nephritis, not specified as acute or chronic)",kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +855,N13,(obstructive and reflux uropathy),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +856,N14,(drug- and heavy-metal-induced tubulo-interstitial and tubular conditions),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +857,N15,(other renal tubulo-interstitial diseases),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +858,N16,(renal tubulo-interstitial disorders in diseases classified elsewhere),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +859,N17,(acute renal failure),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +860,N18,(chronic renal failure),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +861,N19,(unspecified renal failure),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +862,N20,(calculus of kidney and ureter),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +863,N21,(calculus of lower urinary tract),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +864,N22,(calculus of urinary tract in diseases classified elsewhere),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +865,N23,(unspecified renal colic),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +866,N25,(disorders resulting from impaired renal tubular function),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +867,N26,(unspecified contracted kidney),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +868,N27,(small kidney of unknown cause),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +869,N28,"(other disorders of kidney and ureter, not elsewhere classified)",kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +870,N29,(other disorders of kidney and ureter in diseases classified elsewhere),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +871,N30,(cystitis),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +872,N31,"(neuromuscular dysfunction of bladder, not elsewhere classified)",kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +873,N32,(other disorders of bladder),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +874,N33,(bladder disorders in diseases classified elsewhere),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +875,N34,(urethritis and urethral syndrome),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +876,N35,(urethral stricture),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +877,N36,(other disorders of urethra),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +878,N37,(urethral disorders in diseases classified elsewhere),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +879,N39,(other disorders of urinary system),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +880,N40,(hyperplasia of prostate),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +881,N41,(inflammatory diseases of prostate),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +882,N42,(other disorders of prostate),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +883,N43,(hydrocele and spermatocele),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +884,N44,(torsion of testis),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +885,N45,(orchitis and epididymitis),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +886,N46,(male infertility),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +887,N47,"(redundant prepuce, phimosis and paraphimosis)",male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +888,N48,(other disorders of penis),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +889,N49,"(inflammatory disorders of male genital organs, not elsewhere classified)",male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +890,N50,(other disorders of male genital organs),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +891,N51,(disorders of male genital organs in diseases classified elsewhere),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +892,N60,(benign mammary dysplasia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +893,N61,(inflammatory disorders of breast),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +894,N62,(hypertrophy of breast),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +895,N63,(unspecified lump in breast),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +896,N64,(other disorders of breast),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +897,N70,(salpingitis and oophoritis),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +898,N71,"(inflammatory disease of uterus, except cervix)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +899,N72,(inflammatory disease of cervix uteri),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +900,N73,(other female pelvic inflammatory diseases),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +901,N74,(female pelvic inflammatory disorders in diseases classified elsewhere),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +902,N75,(diseases of bartholin's gland),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +903,N76,(other inflammation of vagina and vulva),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +904,N77,(vulvovaginal ulceration and inflammation in diseases classified elsewhere),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +905,N80,(endometriosis),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +906,N81,(female genital prolapse),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +907,N82,(fistulae involving female genital tract),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +908,N83,"(noninflammatory disorders of ovary, fallopian tube and broad ligament)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +909,N84,(polyp of female genital tract),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +910,N85,"(other noninflammatory disorders of uterus, except cervix)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +911,N86,(erosion and ectropion of cervix uteri),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +912,N87,(dysplasia of cervix uteri),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +913,N88,(other noninflammatory disorders of cervix uteri),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +914,N89,(other noninflammatory disorders of vagina),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +915,N90,(other noninflammatory disorders of vulva and perineum),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +916,N91,"(absent, scanty and rare menstruation)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +917,N92,"(excessive, frequent and irregular menstruation)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +918,N93,(other abnormal uterine and vaginal bleeding),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +919,N94,(pain and other conditions associated with female genital organs and menstrual cycle),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +920,N95,(menopausal and other perimenopausal disorders),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +921,N96,(habitual aborter),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +922,N97,(female infertility),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +923,N98,(complications associated with artificial fertilisation),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +924,N99,"(postprocedural disorders of genito-urinary system, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +925,O00,(ectopic pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +926,O01,(hydatidiform mole),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +927,O02,(other abnormal products of conception),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +928,O03,(spontaneous abortion),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +929,O04,(medical abortion),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +930,O05,(other abortion),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +931,O06,(unspecified abortion),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +932,O07,(failed attempted abortion),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +933,O08,(complications following abortion and ectopic and molar pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +934,O10,"(pre-existing hypertension complicating pregnancy, childbirth and the puerperium)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +935,O11,(pre-existing hypertensive disorder with superimposed proteinuria),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +936,O12,(gestational [pregnancy-induced] oedema and proteinuria without hypertension),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +937,O13,(gestational [pregnancy-induced] hypertension without significant proteinuria),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +938,O14,(gestational [pregnancy-induced] hypertension with significant proteinuria),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +939,O15,(eclampsia),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +940,O16,(unspecified maternal hypertension),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +941,O20,(haemorrhage in early pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +942,O21,(excessive vomiting in pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +943,O22,(venous complications in pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +944,O23,(infections of genito-urinary tract in pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +945,O24,(diabetes mellitus in pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +946,O25,(malnutrition in pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +947,O26,(maternal care for other conditions predominantly related to pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +948,O28,(abnormal findings on antenatal screening of mother),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +949,O29,(complications of anaesthesia during pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +950,O30,(multiple gestation),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +951,O31,(complications specific to multiple gestation),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +952,O32,(maternal care for known or suspected malpresentation of foetus),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +953,O33,(maternal care for known or suspected disproportion),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +954,O34,(maternal care for known or suspected abnormality of pelvic organs),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +955,O35,(maternal care for known or suspected foetal abnormality and damage),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +956,O36,(maternal care for other known or suspected foetal problems),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +957,O40,(polyhydramnios),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +958,O41,(other disorders of amniotic fluid and membranes),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +959,O42,(premature rupture of membranes),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +960,O43,(placental disorders),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +961,O44,(placenta praevia),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +962,O45,(premature separation of placenta [abruptio placentae]),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +963,O46,"(antepartum haemorrhage, not elsewhere classified)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +964,O47,(false labour),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +965,O48,(prolonged pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +966,O60,(preterm delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +967,O61,(failed induction of labour),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +968,O62,(abnormalities of forces of labour),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +969,O63,(long labour),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +970,O64,(obstructed labour due to malposition and malpresentation of foetus),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +971,O65,(obstructed labour due to maternal pelvic abnormality),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +972,O66,(other obstructed labour),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +973,O67,"(labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +974,O68,(labour and delivery complicated by foetal stress [distress]),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +975,O69,(labour and delivery complicated by umbilical cord complications),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +976,O70,(perineal laceration during delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +977,O71,(other obstetric trauma),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +978,O72,(postpartum haemorrhage),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +979,O73,"(retained placenta and membranes, without haemorrhage)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +980,O74,(complications of anaesthesia during labour and delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +981,O75,"(other complications of labour and delivery, not elsewhere classified)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +982,O80,(single spontaneous delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +983,O81,(single delivery by forceps and vacuum extractor),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +984,O82,(single delivery by caesarean section),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +985,O83,(other assisted single delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +986,O84,(multiple delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +987,O85,(puerperal sepsis),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +988,O86,(other puerperal infections),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +989,O87,(venous complications in the puerperium),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +990,O88,(obstetric embolism),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +991,O89,(complications of anaesthesia during the puerperium),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +992,O90,"(complications of the puerperium, not elsewhere classified)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +993,O91,(infections of breast associated with childbirth),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +994,O92,(other disorders of breast and lactation associated with childbirth),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +995,O94,"(sequelae of complication of pregnancy, childbirth and the puerperium)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +996,O96,(death from any obstetric cause occurring more than 42 days but less than one year after delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +997,O98,"(maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +998,O99,"(other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +999,P00,(foetus and newborn affected by maternal conditions that may be unrelated to present pregnancy),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1000,P02,"(foetus and newborn affected by complications of placenta, cord and membranes)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1001,P03,(foetus and newborn affected by other complications of labour and delivery),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1002,P04,(foetus and newborn affected by noxious influences transmitted via placenta or breast milk),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1003,P05,(slow foetal growth and foetal malnutrition),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1004,P07,"(disorders related to short gestation and low birth weight, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1005,P08,(disorders related to long gestation and high birth weight),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1006,P10,(intracranial laceration and haemorrhage due to birth injury),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1007,P11,(other birth injuries to central nervous system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1008,P12,(birth injury to scalp),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1009,P13,(birth injury to skeleton),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1010,P14,(birth injury to peripheral nervous system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1011,P15,(other birth injuries),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1012,P20,(intra-uterine hypoxia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1013,P21,(birth asphyxia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1014,P22,(respiratory distress of newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1015,P23,(congenital pneumonia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1016,P24,(neonatal aspiration syndromes),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1017,P25,(interstitial emphysema and related conditions originating in the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1018,P26,(pulmonary haemorrhage originating in the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1019,P27,(chronic respiratory disease originating in the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1020,P28,(other respiratory conditions originating in the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1021,P29,(cardiovascular disorders originating in the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1022,P35,(congenital viral diseases),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1023,P36,(bacterial sepsis of newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1024,P37,(other congenital infectious and parasitic diseases),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1025,P38,(omphalitis of newborn with or without mild haemorrhage),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1026,P39,(other infections specific to the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1027,P50,(foetal blood loss),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1028,P51,(umbilical haemorrhage of newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1029,P52,(intracranial nontraumatic haemorrhage of foetus and newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1030,P53,(haemorrhagic disease of foetus and newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1031,P54,(other neonatal haemorrhages),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1032,P55,(haemolytic disease of foetus and newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1033,P58,(neonatal jaundice due to other excessive haemolysis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1034,P59,(neonatal jaundice from other and unspecified causes),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1035,P61,(other perinatal haematological disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1036,P70,(transitory disorders of carbohydrate metabolism specific to foetus and newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1037,P71,(transitory neonatal disorders of calcium and magnesium metabolism),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1038,P78,(other perinatal digestive system disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1039,P83,(other conditions of integument specific to foetus and newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1040,P91,(other disturbances of cerebral status of newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1041,P92,(feeding problems of newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1042,P94,(disorders of muscle tone of newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1043,P95,(foetal death of unspecified cause),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1044,P96,(other conditions originating in the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1045,Q00,(anencephaly and similar malformations),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1046,Q01,(encephalocele),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1047,Q02,(microcephaly),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1048,Q03,(congenital hydrocephalus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1049,Q04,(other congenital malformations of brain),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1050,Q05,(spina bifida),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1051,Q06,(other congenital malformations of spinal cord),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1052,Q07,(other congenital malformations of nervous system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1053,Q10,"(congenital malformations of eyelid, lachrymal apparatus and orbit)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1054,Q11,"(anophthalmos, microphthalmos and macrophthalmos)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1055,Q12,(congenital lens malformations),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1056,Q13,(congenital malformations of anterior segment of eye),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1057,Q14,(congenital malformations of posterior segment of eye),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1058,Q15,(other congenital malformations of eye),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1059,Q16,(congenital malformations of ear causing impairment of hearing),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1060,Q17,(other congenital malformations of ear),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1061,Q18,(other congenital malformations of face and neck),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1062,Q20,(congenital malformations of cardiac chambers and connexions),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1063,Q21,(congenital malformations of cardiac septa),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1064,Q22,(congenital malformations of pulmonary and tricuspid valves),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1065,Q23,(congenital malformations of aortic and mitral valves),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1066,Q24,(other congenital malformations of heart),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1067,Q25,(congenital malformations of great arteries),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1068,Q26,(congenital malformations of great veins),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1069,Q27,(other congenital malformations of peripheral vascular system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1070,Q28,(other congenital malformations of circulatory system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1071,Q30,(congenital malformations of nose),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1072,Q31,(congenital malformations of larynx),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1073,Q32,(congenital malformations of trachea and bronchus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1074,Q33,(congenital malformations of lung),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1075,Q34,(other congenital malformations of respiratory system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1076,Q35,(cleft palate),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1077,Q36,(cleft lip),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1078,Q37,(cleft palate with cleft lip),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1079,Q38,"(other congenital malformations of tongue, mouth and pharynx)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1080,Q39,(congenital malformations of oesophagus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1081,Q40,(other congenital malformations of upper alimentary tract),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1082,Q41,"(congenital absence, atresia and stenosis of small intestine)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1083,Q42,"(congenital absence, atresia and stenosis of large intestine)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1084,Q43,(other congenital malformations of intestine),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1085,Q44,"(congenital malformations of gallbladder, bile ducts and liver)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1086,Q45,(other congenital malformations of digestive system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1087,Q50,"(congenital malformations of ovaries, fallopian tubes and broad ligaments)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1088,Q51,(congenital malformations of uterus and cervix),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1089,Q52,(other congenital malformations of female genitalia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1090,Q53,(undescended testicle),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1091,Q54,(hypospadias),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1092,Q55,(other congenital malformations of male genital organs),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1093,Q56,(indeterminate sex and pseudohermaphroditism),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1094,Q60,(renal agenesis and other reduction defects of kidney),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1095,Q61,(cystic kidney disease),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1096,Q62,(congenital obstructive defects of renal pelvis and congenital malformations of ureter),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1097,Q63,(other congenital malformations of kidney),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1098,Q64,(other congenital malformations of urinary system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1099,Q65,(congenital deformities of hip),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1100,Q66,(congenital deformities of feet),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1101,Q67,"(congenital musculoskeletal deformities of head, face, spine and chest)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1102,Q68,(other congenital musculoskeletal deformities),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1103,Q69,(polydactyly),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1104,Q70,(syndactyly),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1105,Q71,(reduction defects of upper limb),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1106,Q72,(reduction defects of lower limb),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1107,Q73,(reduction defects of unspecified limb),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1108,Q74,(other congenital malformations of limb(s)),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1109,Q75,(other congenital malformations of skull and face bones),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1110,Q76,(congenital malformations of spine and bony thorax),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1111,Q77,(osteochondrodysplasia with defects of growth of tubular bones and spine),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1112,Q78,(other osteochondrodysplasias),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1113,Q79,"(congenital malformations of musculoskeletal system, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1114,Q80,(congenital ichthyosis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1115,Q81,(epidermolysis bullosa),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1116,Q82,(other congenital malformations of skin),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1117,Q83,(congenital malformations of breast),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1118,Q84,(other congenital malformations of integument),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1119,Q85,"(phakomatoses, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1120,Q86,"(congenital malformation syndromes due to known exogenous causes, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1121,Q87,(other specified congenital malformation syndromes affecting multiple systems),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1122,Q89,"(other congenital malformations, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1123,Q90,(down's syndrome),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1124,Q91,(edwards' syndrome and patau's syndrome),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1125,Q92,"(other trisomies and partial trisomies of the autosomes, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1126,Q93,"(monosomies and deletions from the autosomes, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1127,Q95,"(balanced rearrangements and structural markers, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1128,Q96,(turner's syndrome),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1129,Q97,"(other sex chromosome abnormalities, female phenotype, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1130,Q98,"(other sex chromosome abnormalities, male phenotype, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1131,Q99,"(other chromosome abnormalities, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1132,CXX,Unknown Cancer,,,0.0,unmapped_non_icd10,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1133,C00,Malignant neoplasm of lip,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1134,C01,Malignant neoplasm of base of tongue,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1135,C02,Malignant neoplasm of other and unspecified parts of tongue,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1136,C03,Malignant neoplasm of gum,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1137,C04,Malignant neoplasm of floor of mouth,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1138,C05,Malignant neoplasm of palate,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1139,C06,Malignant neoplasm of other and unspecified parts of mouth,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1140,C07,Malignant neoplasm of parotid gland,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1141,C08,Malignant neoplasm of other and unspecified major salivary glands,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1142,C09,Malignant neoplasm of tonsil,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1143,C10,Malignant neoplasm of oropharynx,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1144,C11,Malignant neoplasm of nasopharynx,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1145,C12,Malignant neoplasm of pyriform sinus,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1146,C13,Malignant neoplasm of hypopharynx,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1147,C14,"Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1148,C15,Malignant neoplasm of oesophagus,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1149,C16,Malignant neoplasm of stomach,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1150,C17,Malignant neoplasm of small intestine,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1151,C18,Malignant neoplasm of colon,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1152,C19,Malignant neoplasm of rectosigmoid junction,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1153,C20,Malignant neoplasm of rectum,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1154,C21,Malignant neoplasm of anus and anal canal,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1155,C22,Malignant neoplasm of liver and intrahepatic bile ducts,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1156,C23,Malignant neoplasm of gallbladder,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1157,C24,Malignant neoplasm of other and unspecified parts of biliary tract,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1158,C25,Malignant neoplasm of pancreas,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1159,C26,Malignant neoplasm of other and ill-defined digestive organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1160,C30,Malignant neoplasm of nasal cavity and middle ear,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1161,C31,Malignant neoplasm of accessory sinuses,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1162,C32,Malignant neoplasm of larynx,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1163,C33,Malignant neoplasm of trachea,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1164,C34,Malignant neoplasm of bronchus and lung,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1165,C37,Malignant neoplasm of thymus,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1166,C38,"Malignant neoplasm of heart, mediastinum and pleura",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1167,C39,Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1168,C40,Malignant neoplasm of bone and articular cartilage of limbs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1169,C41,Malignant neoplasm of bone and articular cartilage of other and unspecified sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1170,C42,hematopoietic and reticuloendothelial systems (ICD-O-3 specific),neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1171,C43,Malignant melanoma of skin,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1172,C44,Other malignant neoplasms of skin,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1173,C45,Mesothelioma,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1174,C46,Kaposi's sarcoma,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1175,C47,Malignant neoplasm of peripheral nerves and autonomic nervous system,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1176,C48,Malignant neoplasm of retroperitoneum and peritoneum,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1177,C49,Malignant neoplasm of other connective and soft tissue,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1178,C50,Malignant neoplasm of breast,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1179,C51,Malignant neoplasm of vulva,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1180,C52,Malignant neoplasm of vagina,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1181,C53,Malignant neoplasm of cervix uteri,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1182,C54,Malignant neoplasm of corpus uteri,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1183,C55,"Malignant neoplasm of uterus, part unspecified",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1184,C56,Malignant neoplasm of ovary,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1185,C57,Malignant neoplasm of other and unspecified female genital organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1186,C58,Malignant neoplasm of placenta,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1187,C60,Malignant neoplasm of penis,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1188,C61,Malignant neoplasm of prostate,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1189,C62,Malignant neoplasm of testis,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1190,C63,Malignant neoplasm of other and unspecified male genital organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1191,C64,"Malignant neoplasm of kidney, except renal pelvis",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1192,C65,Malignant neoplasm of renal pelvis,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1193,C66,Malignant neoplasm of ureter,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1194,C67,Malignant neoplasm of bladder,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1195,C68,Malignant neoplasm of other and unspecified urinary organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1196,C69,Malignant neoplasm of eye and adnexa,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1197,C70,Malignant neoplasm of meninges,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1198,C71,Malignant neoplasm of brain,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1199,C72,"Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1200,C73,Malignant neoplasm of thyroid gland,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1201,C74,Malignant neoplasm of adrenal gland,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1202,C75,Malignant neoplasm of other endocrine glands and related structures,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1203,C76,Malignant neoplasm of other and ill-defined sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1204,C77,Secondary and unspecified malignant neoplasm of lymph nodes,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1205,C78,Secondary malignant neoplasm of respiratory and digestive organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1206,C79,Secondary malignant neoplasm of other sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1207,C80,Malignant neoplasm without specification of site,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1208,C81,Hodgkin's disease,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1209,C82,Follicular [nodular] non-Hodgkin's lymphoma,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1210,C83,Diffuse non-Hodgkin's lymphoma,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1211,C84,Peripheral and cutaneous T-cell lymphomas,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1212,C85,Other and unspecified types of non-Hodgkin's lymphoma,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1213,C86,Other specified types of T/NK-cell lymphoma,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1214,C88,Malignant immunoproliferative diseases,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1215,C90,Multiple myeloma and malignant plasma cell neoplasms,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1216,C91,Lymphoid leukaemia,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1217,C92,Myeloid leukaemia,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1218,C93,Monocytic leukaemia,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1219,C94,Other leukaemias of specified cell type,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1220,C95,Leukaemia of unspecified cell type,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1221,C96,"Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1222,C97,Malignant neoplasms of independent (primary) multiple sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1223,D00,"Carcinoma in situ of oral cavity, oesophagus and stomach",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1224,D01,Carcinoma in situ of other and unspecified digestive organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1225,D02,Carcinoma in situ of middle ear and respiratory system,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1226,D03,Melanoma in situ,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1227,D04,Carcinoma in situ of skin,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1228,D05,Carcinoma in situ of breast,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1229,D06,Carcinoma in situ of cervix uteri,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1230,D07,Carcinoma in situ of other and unspecified genital organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1231,D09,Carcinoma in situ of other and unspecified sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1232,D10,Benign neoplasm of mouth and pharynx,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1233,D11,Benign neoplasm of major salivary glands,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1234,D12,"Benign neoplasm of colon, rectum, anus and anal canal",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1235,D13,Benign neoplasm of other and ill-defined parts of digestive system,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1236,D15,Benign neoplasm of other and unspecified intrathoracic organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1237,D16,Benign neoplasm of bone and articular cartilage,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1238,D18,"Haemangioma and lymphangioma, any site",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1239,D27,Benign neoplasm of ovary,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1240,D30,Benign neoplasm of urinary organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1241,D32,Benign neoplasm of meninges,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1242,D33,Benign neoplasm of brain and other parts of central nervous system,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1243,D34,Benign neoplasm of thyroid gland,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1244,D35,Benign neoplasm of other and unspecified endocrine glands,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1245,D36,Benign neoplasm of other and unspecified sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1246,D37,Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1247,D38,Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1248,D39,Neoplasm of uncertain or unknown behaviour of female genital organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1249,D40,Neoplasm of uncertain or unknown behaviour of male genital organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1250,D41,Neoplasm of uncertain or unknown behaviour of urinary organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1251,D42,Neoplasm of uncertain or unknown behaviour of meninges,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1252,D43,Neoplasm of uncertain or unknown behaviour of brain and central nervous system,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1253,D44,Neoplasm of uncertain or unknown behaviour of endocrine glands,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1254,D45,Polycythaemia vera,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1255,D46,Myelodysplastic syndromes,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1256,D47,"Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1257,D48,Neoplasm of uncertain or unknown behaviour of other and unspecified sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules +1258,DEATH,,,,0.0,unmapped_non_icd10,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules diff --git a/plot_burden_index_trajectories.py b/plot_burden_index_trajectories.py deleted file mode 100644 index ecbb118..0000000 --- a/plot_burden_index_trajectories.py +++ /dev/null @@ -1,258 +0,0 @@ -from __future__ import annotations - -import argparse -from pathlib import Path -from typing import Iterable - -try: - import matplotlib - - matplotlib.use("Agg") - import matplotlib.pyplot as plt -except ModuleNotFoundError as exc: - raise ModuleNotFoundError( - "plot_burden_index_trajectories.py requires matplotlib. " - "Install it in the server environment before running this script." - ) from exc -import numpy as np -import pandas as pd - - -REQUIRED_COLUMNS = { - "patient_id", - "sex", - "landmark_age", - "burden_type", - "burden_dimension", - "bi_historical", - "bi_future", - "bi_total", -} - - -def _sex_label(value: object) -> str: - text = str(value).strip().lower() - if text in {"0", "0.0", "female", "f", "woman"}: - return "female" - if text in {"1", "1.0", "male", "m", "man"}: - return "male" - return text or "unknown" - - -def _load_bi_csv(path: Path) -> pd.DataFrame: - header = pd.read_csv(path, nrows=0) - missing = sorted(REQUIRED_COLUMNS - set(header.columns)) - if missing: - raise ValueError(f"{path} is missing required columns: {missing}") - - df = pd.read_csv( - path, - usecols=[ - "patient_id", - "sex", - "landmark_age", - "burden_type", - "burden_dimension", - "bi_historical", - "bi_future", - "bi_total", - ], - ) - df["sex_label"] = df["sex"].map(_sex_label) - df["landmark_age"] = pd.to_numeric(df["landmark_age"], errors="raise") - for col in ["bi_historical", "bi_future", "bi_total"]: - df[col] = pd.to_numeric(df[col], errors="raise") - return df - - -def _sample_patients( - df: pd.DataFrame, - *, - n_per_sex: int, - seed: int, -) -> dict[str, np.ndarray]: - rng = np.random.default_rng(int(seed)) - samples: dict[str, np.ndarray] = {} - for sex_label in ["female", "male"]: - ids = np.asarray(sorted(df.loc[df["sex_label"] == sex_label, "patient_id"].unique())) - if ids.size == 0: - samples[sex_label] = np.asarray([], dtype=np.int64) - continue - take = min(int(n_per_sex), int(ids.size)) - samples[sex_label] = np.asarray(rng.choice(ids, size=take, replace=False)) - return samples - - -def _aggregate_total(df: pd.DataFrame) -> pd.DataFrame: - return ( - df.groupby(["patient_id", "sex_label", "burden_type", "landmark_age"], as_index=False) - [["bi_historical", "bi_future", "bi_total"]] - .sum() - ) - - -def _plot_selected_trajectories( - total_df: pd.DataFrame, - *, - burden_type: str, - selected: dict[str, np.ndarray], - output_dir: Path, -) -> None: - sub = total_df[total_df["burden_type"] == burden_type].copy() - mean_df = ( - sub.groupby(["sex_label", "landmark_age"], as_index=False)["bi_total"] - .mean() - .sort_values("landmark_age") - ) - - fig, ax = plt.subplots(figsize=(9.5, 5.5), dpi=160) - colors = {"female": "#b83280", "male": "#2563eb"} - for sex_label in ["female", "male"]: - patient_ids = selected.get(sex_label, np.asarray([], dtype=np.int64)) - for pid in patient_ids: - one = sub[sub["patient_id"] == pid].sort_values("landmark_age") - if one.empty: - continue - ax.plot( - one["landmark_age"], - one["bi_total"], - color=colors.get(sex_label, "0.4"), - alpha=0.22, - linewidth=1.0, - ) - mean_one = mean_df[mean_df["sex_label"] == sex_label] - if not mean_one.empty: - ax.plot( - mean_one["landmark_age"], - mean_one["bi_total"], - color=colors.get(sex_label, "0.4"), - linewidth=2.8, - label=f"{sex_label} mean", - ) - - ax.set_title(f"{burden_type}: sampled individual trajectories and sex-specific means") - ax.set_xlabel("Landmark age") - ax.set_ylabel("Total burden index") - ax.grid(True, alpha=0.25) - ax.legend(frameon=False) - fig.tight_layout() - fig.savefig(output_dir / f"{burden_type}_sampled_trajectories_by_sex.png") - plt.close(fig) - - -def _top_dimensions(df: pd.DataFrame, *, burden_type: str, top_n: int) -> list[str]: - sub = df[df["burden_type"] == burden_type] - if sub.empty: - return [] - ranked = ( - sub.groupby("burden_dimension")["bi_total"] - .mean() - .sort_values(ascending=False) - .head(int(top_n)) - ) - return [str(x) for x in ranked.index.tolist()] - - -def _plot_dimension_mean_panels( - df: pd.DataFrame, - *, - burden_type: str, - dimensions: Iterable[str], - output_dir: Path, -) -> None: - dims = list(dimensions) - if not dims: - return - - mean_df = ( - df[(df["burden_type"] == burden_type) & (df["burden_dimension"].isin(dims))] - .groupby(["sex_label", "burden_dimension", "landmark_age"], as_index=False)["bi_total"] - .mean() - .sort_values("landmark_age") - ) - n_cols = min(3, len(dims)) - n_rows = int(np.ceil(len(dims) / n_cols)) - fig, axes = plt.subplots( - n_rows, - n_cols, - figsize=(4.2 * n_cols, 3.2 * n_rows), - dpi=160, - squeeze=False, - ) - colors = {"female": "#b83280", "male": "#2563eb"} - for ax, dim in zip(axes.ravel(), dims): - panel = mean_df[mean_df["burden_dimension"] == dim] - for sex_label in ["female", "male"]: - one = panel[panel["sex_label"] == sex_label] - if one.empty: - continue - ax.plot( - one["landmark_age"], - one["bi_total"], - color=colors.get(sex_label, "0.4"), - linewidth=2.0, - label=sex_label, - ) - ax.set_title(str(dim), fontsize=9) - ax.set_xlabel("Age") - ax.set_ylabel("Mean BI") - ax.grid(True, alpha=0.25) - - for ax in axes.ravel()[len(dims):]: - ax.axis("off") - handles, labels = axes.ravel()[0].get_legend_handles_labels() - if handles: - fig.legend(handles, labels, loc="upper right", frameon=False) - fig.suptitle(f"{burden_type}: sex-specific mean trajectories for top dimensions") - fig.tight_layout(rect=(0, 0, 0.98, 0.95)) - fig.savefig(output_dir / f"{burden_type}_top_dimension_means_by_sex.png") - plt.close(fig) - - -def main() -> None: - parser = argparse.ArgumentParser( - description="Plot DeepHealth burden-index trajectories by sex." - ) - parser.add_argument("--input_csv", type=str, required=True) - parser.add_argument("--output_dir", type=str, default=None) - parser.add_argument("--n_per_sex", type=int, default=10) - parser.add_argument("--seed", type=int, default=2026) - parser.add_argument("--top_dimensions", type=int, default=12) - args = parser.parse_args() - - input_csv = Path(args.input_csv) - output_dir = Path(args.output_dir) if args.output_dir else input_csv.with_suffix("") - output_dir.mkdir(parents=True, exist_ok=True) - - df = _load_bi_csv(input_csv) - total_df = _aggregate_total(df) - selected = _sample_patients(total_df, n_per_sex=int(args.n_per_sex), seed=int(args.seed)) - - for burden_type in sorted(df["burden_type"].dropna().unique().tolist()): - burden_type = str(burden_type) - _plot_selected_trajectories( - total_df, - burden_type=burden_type, - selected=selected, - output_dir=output_dir, - ) - dims = _top_dimensions(df, burden_type=burden_type, top_n=int(args.top_dimensions)) - _plot_dimension_mean_panels( - df, - burden_type=burden_type, - dimensions=dims, - output_dir=output_dir, - ) - - selected_rows = [] - for sex_label, patient_ids in selected.items(): - for pid in patient_ids.tolist(): - selected_rows.append({"sex": sex_label, "patient_id": int(pid)}) - pd.DataFrame(selected_rows).to_csv(output_dir / "sampled_patients_by_sex.csv", index=False) - print(f"Input: {input_csv}") - print(f"Output directory: {output_dir}") - print(f"Sampled patients per sex: {int(args.n_per_sex)}") - - -if __name__ == "__main__": - main() diff --git a/plot_deephealth_index_trajectories.py b/plot_deephealth_index_trajectories.py new file mode 100644 index 0000000..f61ca87 --- /dev/null +++ b/plot_deephealth_index_trajectories.py @@ -0,0 +1,214 @@ +from __future__ import annotations + +import argparse +from pathlib import Path + +try: + import matplotlib + + matplotlib.use("Agg") + import matplotlib.pyplot as plt +except ModuleNotFoundError as exc: + raise ModuleNotFoundError( + "plot_deephealth_index_trajectories.py requires matplotlib. " + "Install it in the server environment before running this script." + ) from exc +import numpy as np +import pandas as pd + + +REQUIRED_COLUMNS = { + "patient_id", + "sex", + "landmark_age", + "index_type", + "index_id", + "index_label", + "index_value", +} + + +def _sex_label(value: object) -> str: + text = str(value).strip().lower() + if text in {"0", "0.0", "female", "f", "woman"}: + return "female" + if text in {"1", "1.0", "male", "m", "man"}: + return "male" + return text or "unknown" + + +def _load_index_csv(path: Path) -> pd.DataFrame: + header = pd.read_csv(path, nrows=0) + missing = sorted(REQUIRED_COLUMNS - set(header.columns)) + if missing: + raise ValueError(f"{path} is missing required columns: {missing}") + df = pd.read_csv(path, usecols=sorted(REQUIRED_COLUMNS)) + df["sex_label"] = df["sex"].map(_sex_label) + df["landmark_age"] = pd.to_numeric(df["landmark_age"], errors="raise") + df["index_value"] = pd.to_numeric(df["index_value"], errors="raise") + return df + + +def _sample_patients(df: pd.DataFrame, *, n_per_sex: int, seed: int) -> dict[str, np.ndarray]: + rng = np.random.default_rng(int(seed)) + samples: dict[str, np.ndarray] = {} + for sex_label in ["female", "male"]: + ids = np.asarray(sorted(df.loc[df["sex_label"] == sex_label, "patient_id"].unique())) + if ids.size == 0: + samples[sex_label] = np.asarray([], dtype=np.int64) + continue + samples[sex_label] = np.asarray( + rng.choice(ids, size=min(int(n_per_sex), int(ids.size)), replace=False) + ) + return samples + + +def _plot_sampled_trajectories( + df: pd.DataFrame, + *, + index_type: str, + selected: dict[str, np.ndarray], + output_dir: Path, +) -> None: + sub = df[df["index_type"] == index_type].copy() + if sub.empty: + return + if index_type == "organ_involvement": + total = ( + sub.groupby(["patient_id", "sex_label", "landmark_age"], as_index=False)[ + "index_value" + ] + .mean() + .rename(columns={"index_value": "trajectory_value"}) + ) + title = "mean organ involvement" + else: + total = sub.rename(columns={"index_value": "trajectory_value"}) + title = "frailty risk" + + mean_df = ( + total.groupby(["sex_label", "landmark_age"], as_index=False)["trajectory_value"] + .mean() + .sort_values("landmark_age") + ) + + fig, ax = plt.subplots(figsize=(9.5, 5.5), dpi=160) + colors = {"female": "#b83280", "male": "#2563eb"} + for sex_label in ["female", "male"]: + for pid in selected.get(sex_label, np.asarray([], dtype=np.int64)): + one = total[total["patient_id"] == pid].sort_values("landmark_age") + if one.empty: + continue + ax.plot( + one["landmark_age"], + one["trajectory_value"], + color=colors.get(sex_label, "0.4"), + alpha=0.22, + linewidth=1.2, + ) + mean_one = mean_df[mean_df["sex_label"] == sex_label] + if not mean_one.empty: + ax.plot( + mean_one["landmark_age"], + mean_one["trajectory_value"], + color=colors.get(sex_label, "0.4"), + linewidth=2.6, + label=f"{sex_label} mean", + ) + + ax.set_title(f"{index_type}: sampled trajectories and sex-specific means") + ax.set_xlabel("Landmark age") + ax.set_ylabel(title) + ax.grid(True, alpha=0.25) + ax.legend(frameon=False) + fig.tight_layout() + fig.savefig(output_dir / f"{index_type}_sampled_trajectories_by_sex.png") + plt.close(fig) + + +def _plot_top_dimensions( + df: pd.DataFrame, + *, + output_dir: Path, + top_n: int, +) -> None: + sub = df[df["index_type"] == "organ_involvement"].copy() + if sub.empty: + return + order = ( + sub.groupby("index_id")["index_value"] + .mean() + .sort_values(ascending=False) + .head(int(top_n)) + .index.tolist() + ) + n = len(order) + if n == 0: + return + ncols = min(3, n) + nrows = int(np.ceil(n / ncols)) + fig, axes = plt.subplots(nrows, ncols, figsize=(4.0 * ncols, 3.0 * nrows), dpi=160) + axes_arr = np.asarray(axes).reshape(-1) + colors = {"female": "#b83280", "male": "#2563eb"} + for ax, index_id in zip(axes_arr, order): + one = sub[sub["index_id"] == index_id] + mean_df = ( + one.groupby(["sex_label", "landmark_age"], as_index=False)["index_value"] + .mean() + .sort_values("landmark_age") + ) + for sex_label in ["female", "male"]: + m = mean_df[mean_df["sex_label"] == sex_label] + if not m.empty: + ax.plot( + m["landmark_age"], + m["index_value"], + color=colors.get(sex_label, "0.4"), + linewidth=1.8, + label=sex_label, + ) + ax.set_title(str(index_id), fontsize=9) + ax.set_xlabel("Age") + ax.set_ylabel("Organ involvement") + ax.grid(True, alpha=0.22) + for ax in axes_arr[n:]: + ax.axis("off") + handles, labels = axes_arr[0].get_legend_handles_labels() + if handles: + fig.legend(handles, labels, loc="upper right", frameon=False) + fig.suptitle("organ_involvement: sex-specific mean trajectories for top dimensions") + fig.tight_layout(rect=(0, 0, 0.98, 0.96)) + fig.savefig(output_dir / "organ_involvement_top_dimensions_by_sex.png") + plt.close(fig) + + +def main() -> None: + parser = argparse.ArgumentParser( + description="Plot DeepHealth organ involvement and frailty risk trajectories." + ) + parser.add_argument("--input_csv", type=str, required=True) + parser.add_argument("--output_dir", type=str, default=None) + parser.add_argument("--n_per_sex", type=int, default=10) + parser.add_argument("--seed", type=int, default=2026) + parser.add_argument("--top_n", type=int, default=12) + args = parser.parse_args() + + input_csv = Path(args.input_csv) + output_dir = Path(args.output_dir) if args.output_dir else input_csv.parent + output_dir.mkdir(parents=True, exist_ok=True) + df = _load_index_csv(input_csv) + selected = _sample_patients(df, n_per_sex=int(args.n_per_sex), seed=int(args.seed)) + for index_type in ["organ_involvement", "frailty_risk"]: + _plot_sampled_trajectories( + df, + index_type=index_type, + selected=selected, + output_dir=output_dir, + ) + _plot_top_dimensions(df, output_dir=output_dir, top_n=int(args.top_n)) + print(f"Input: {input_csv}") + print(f"Output directory: {output_dir}") + + +if __name__ == "__main__": + main() diff --git a/uk_hfrs_label_mapping.csv b/uk_hfrs_label_mapping.csv new file mode 100644 index 0000000..c49f1a3 --- /dev/null +++ b/uk_hfrs_label_mapping.csv @@ -0,0 +1,1257 @@ +token_id,label_code,label_name,hfrs_dimension_id,hfrs_dimension,hfrs_key_area,hfrs_weight,hfrs_source,match_source +3,A00,(cholera),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +4,A01,(typhoid and paratyphoid fevers),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +5,A02,(other salmonella infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +6,A03,(shigellosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +7,A04,(other bacterial intestinal infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.1,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +8,A05,(other bacterial foodborne intoxications),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +9,A06,(amoebiasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +10,A07,(other protozoal intestinal diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +11,A08,(viral and other specified intestinal infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +12,A09,(diarrhoea and gastro-enteritis of presumed infectious origin),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.1,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +13,A15,"(respiratory tuberculosis, bacteriologically and histologically confirmed)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +14,A16,"(respiratory tuberculosis, not confirmed bacteriologically or histologically)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +15,A17,(tuberculosis of nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +16,A18,(tuberculosis of other organs),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +17,A19,(miliary tuberculosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +18,A20,(plague),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +19,A22,(anthrax),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +20,A23,(brucellosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +21,A24,(glanders and melioidosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +22,A25,(rat-bite fevers),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +23,A26,(erysipeloid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +24,A27,(leptospirosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +25,A28,"(other zoonotic bacterial diseases, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +26,A30,(leprosy [hansen's disease]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +27,A31,(infection due to other mycobacteria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +28,A32,(listeriosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +29,A33,(tetanus neonatorum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +30,A35,(other tetanus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +31,A36,(diphtheria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +32,A37,(whooping cough),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +33,A38,(scarlet fever),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +34,A39,(meningococcal infection),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +35,A40,(streptococcal septicaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +36,A41,(other septicaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.6,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +37,A42,(actinomycosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +38,A43,(nocardiosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +39,A44,(bartonellosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +40,A46,(erysipelas),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +41,A48,"(other bacterial diseases, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +42,A49,(bacterial infection of unspecified site),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +43,A50,(congenital syphilis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +44,A51,(early syphilis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +45,A52,(late syphilis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +46,A53,(other and unspecified syphilis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +47,A54,(gonococcal infection),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +48,A55,(chlamydial lymphogranuloma (venereum)),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +49,A56,(other sexually transmitted chlamydial diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +50,A58,(granuloma inguinale),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +51,A59,(trichomoniasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +52,A60,(anogenital herpesviral [herpes simplex] infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +53,A63,"(other predominantly sexually transmitted diseases, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +54,A64,(unspecified sexually transmitted disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +55,A66,(yaws),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +56,A67,(pinta [carate]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +57,A68,(relapsing fevers),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +58,A69,(other spirochaetal infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +59,A70,(chlamydia psittaci infection),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +60,A71,(trachoma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +61,A74,(other diseases caused by chlamydiae),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +62,A75,(typhus fever),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +63,A77,(spotted fever [tick-borne rickettsioses]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +64,A78,(q fever),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +65,A79,(other rickettsioses),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +66,A80,(acute poliomyelitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +67,A81,(atypical virus infections of central nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +68,A82,(rabies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +69,A83,(mosquito-borne viral encephalitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +70,A84,(tick-borne viral encephalitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +71,A85,"(other viral encephalitis, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +72,A86,(unspecified viral encephalitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +73,A87,(viral meningitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +74,A88,"(other viral infections of central nervous system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +75,A89,(unspecified viral infection of central nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +76,A90,(dengue fever [classical dengue]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +77,A91,(dengue haemorrhagic fever),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +78,A92,(other mosquito-borne viral fevers),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +79,A93,"(other arthropod-borne viral fevers, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +80,A94,(unspecified arthropod-borne viral fever),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +81,A95,(yellow fever),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +82,A97,(dengue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +83,A98,"(other viral haemorrhagic fevers, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +84,B00,(herpesviral [herpes simplex] infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +85,B01,(varicella [chickenpox]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +86,B02,(zoster [herpes zoster]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +87,B03,(smallpox),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +88,B05,(measles),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +89,B06,(rubella [german measles]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +90,B07,(viral warts),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +91,B08,"(other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +92,B09,(unspecified viral infection characterised by skin and mucous membrane lesions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +93,B15,(acute hepatitis a),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +94,B16,(acute hepatitis b),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +95,B17,(other acute viral hepatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +96,B18,(chronic viral hepatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +97,B19,(unspecified viral hepatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +98,B20,(human immunodeficiency virus [hiv] disease resulting in infectious and parasitic diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +99,B21,(human immunodeficiency virus [hiv] disease resulting in malignant neoplasms),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +100,B22,(human immunodeficiency virus [hiv] disease resulting in other specified diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +101,B23,(human immunodeficiency virus [hiv] disease resulting in other conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +102,B24,(unspecified human immunodeficiency virus [hiv] disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +103,B25,(cytomegaloviral disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +104,B26,(mumps),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +105,B27,(infectious mononucleosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +106,B30,(viral conjunctivitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +107,B33,"(other viral diseases, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +108,B34,(viral infection of unspecified site),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +109,B35,(dermatophytosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +110,B36,(other superficial mycoses),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +111,B37,(candidiasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +112,B38,(coccidioidomycosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +113,B39,(histoplasmosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +114,B40,(blastomycosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +115,B42,(sporotrichosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +116,B43,(chromomycosis and phaeomycotic abscess),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +117,B44,(aspergillosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +118,B45,(cryptococcosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +119,B46,(zygomycosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +120,B47,(mycetoma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +121,B48,"(other mycoses, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +122,B49,(unspecified mycosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +123,B50,(plasmodium falciparum malaria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +124,B51,(plasmodium vivax malaria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +125,B52,(plasmodium malariae malaria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +126,B53,(other parasitologically confirmed malaria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +127,B54,(unspecified malaria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +128,B55,(leishmaniasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +129,B57,(chagas' disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +130,B58,(toxoplasmosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +131,B59,(pneumocystosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +132,B60,"(other protozoal diseases, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +133,B65,(schistosomiasis [bilharziasis]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +134,B66,(other fluke infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +135,B67,(echinococcosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +136,B68,(taeniasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +137,B69,(cysticercosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +138,B71,(other cestode infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +139,B73,(onchocerciasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +140,B74,(filariasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +141,B75,(trichinellosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +142,B76,(hookworm diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +143,B77,(ascariasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +144,B78,(strongyloidiasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +145,B79,(trichuriasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +146,B80,(enterobiasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +147,B81,"(other intestinal helminthiases, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +148,B82,(unspecified intestinal parasitism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +149,B83,(other helminthiases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +150,B85,(pediculosis and phthiriasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +151,B86,(scabies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +152,B87,(myiasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +153,B88,(other infestations),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +154,B89,(unspecified parasitic disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +155,B90,(sequelae of tuberculosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +156,B91,(sequelae of poliomyelitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +157,B94,(sequelae of other and unspecified infectious and parasitic diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +158,B95,(streptococcus and staphylococcus as the cause of diseases classified to other chapters),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.7,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +159,B96,(other bacterial agents as the cause of diseases classified to other chapters),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.9,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +160,B97,(viral agents as the cause of diseases classified to other chapters),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +161,B98,(other specified infectious agents as the cause of diseases classified to other chapters),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +162,B99,(other and unspecified infectious diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +163,D50,(iron deficiency anaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +164,D51,(vitamin b12 deficiency anaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +165,D52,(folate deficiency anaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +166,D53,(other nutritional anaemias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +167,D55,(anaemia due to enzyme disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +168,D56,(thalassaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +169,D57,(sickle-cell disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +170,D58,(other hereditary haemolytic anaemias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +171,D59,(acquired haemolytic anaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +172,D60,(acquired pure red cell aplasia [erythroblastopenia]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +173,D61,(other aplastic anaemias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +174,D62,(acute posthaemorrhagic anaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +175,D63,(anaemia in chronic diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +176,D64,(other anaemias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +177,D65,(disseminated intravascular coagulation [defibrination syndrome]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +178,D66,(hereditary factor viii deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +179,D67,(hereditary factor ix deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +180,D68,(other coagulation defects),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +181,D69,(purpura and other haemorrhagic conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +182,D70,(agranulocytosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +183,D71,(functional disorders of polymorphonuclear neutrophils),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +184,D72,(other disorders of white blood cells),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +185,D73,(diseases of spleen),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +186,D74,(methaemoglobinaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +187,D75,(other diseases of blood and blood-forming organs),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +188,D76,(certain diseases involving lymphoreticular tissue and reticulohistiocytic system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +189,D77,(other disorders of blood and blood-forming organs in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +190,D80,(immunodeficiency with predominantly antibody defects),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +191,D81,(combined immunodeficiencies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +192,D82,(immunodeficiency associated with other major defects),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +193,D83,(common variable immunodeficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +194,D84,(other immunodeficiencies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +195,D86,(sarcoidosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +196,D89,"(other disorders involving the immune mechanism, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +197,E01,(iodine-deficiency-related thyroid disorders and allied conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +198,E02,(subclinical iodine-deficiency hypothyroidism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +199,E03,(other hypothyroidism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +200,E04,(other non-toxic goitre),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +201,E05,(thyrotoxicosis [hyperthyroidism]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.9,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +202,E06,(thyroiditis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +203,E07,(other disorders of thyroid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +204,E10,(insulin-dependent diabetes mellitus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +205,E11,(non-insulin-dependent diabetes mellitus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +206,E12,(malnutrition-related diabetes mellitus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +207,E13,(other specified diabetes mellitus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +208,E14,(unspecified diabetes mellitus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +209,E15,(nondiabetic hypoglycaemic coma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +210,E16,(other disorders of pancreatic internal secretion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +211,E20,(hypoparathyroidism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +212,E21,(hyperparathyroidism and other disorders of parathyroid gland),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +213,E22,(hyperfunction of pituitary gland),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +214,E23,(hypofunction and other disorders of pituitary gland),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +215,E24,(cushing's syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +216,E25,(adrenogenital disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +217,E26,(hyperaldosteronism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +218,E27,(other disorders of adrenal gland),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +219,E28,(ovarian dysfunction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +220,E29,(testicular dysfunction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +221,E30,"(disorders of puberty, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +222,E31,(polyglandular dysfunction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +223,E32,(diseases of thymus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +224,E34,(other endocrine disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +225,E35,(disorders of endocrine glands in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +226,E41,(nutritional marasmus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +227,E43,(unspecified severe protein-energy malnutrition),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +228,E44,(protein-energy malnutrition of moderate and mild degree),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +229,E45,(retarded development following protein-energy malnutrition),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +230,E46,(unspecified protein-energy malnutrition),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +231,E50,(vitamin a deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +232,E51,(thiamine deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +233,E52,(niacin deficiency [pellagra]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +234,E53,(deficiency of other b group vitamins),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.9,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +235,E54,(ascorbic acid deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +236,E55,(vitamin d deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +237,E56,(other vitamin deficiencies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +238,E58,(dietary calcium deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +239,E59,(dietary selenium deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +240,E60,(dietary zinc deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +241,E61,(deficiency of other nutrient elements),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +242,E63,(other nutritional deficiencies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +243,E64,(sequelae of malnutrition and other nutritional deficiencies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +244,E65,(localised adiposity),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +245,E66,(obesity),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +246,E67,(other hyperalimentation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +247,E68,(sequelae of hyperalimentation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +248,E70,(disorders of aromatic amino-acid metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +249,E71,(disorders of branched-chain amino-acid metabolism and fatty-acid metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +250,E72,(other disorders of amino-acid metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +251,E73,(lactose intolerance),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +252,E74,(other disorders of carbohydrate metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +253,E75,(disorders of sphingolipid metabolism and other lipid storage disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +254,E76,(disorders of glycosaminoglycan metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +255,E77,(disorders of glycoprotein metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +256,E78,(disorders of lipoprotein metabolism and other lipidaemias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +257,E79,(disorders of purine and pyrimidine metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +258,E80,(disorders of porphyrin and bilirubin metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +259,E83,(disorders of mineral metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +260,E84,(cystic fibrosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +261,E85,(amyloidosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +262,E86,(volume depletion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.3,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +263,E87,"(other disorders of fluid, electrolyte and acid-base balance)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.3,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +264,E88,(other metabolic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +265,E89,"(postprocedural endocrine and metabolic disorders, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +266,F00,(dementia in alzheimer's disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,7.1,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +267,F01,(vascular dementia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +268,F02,(dementia in other diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +269,F03,(unspecified dementia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.1,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +270,F04,"(organic amnesic syndrome, not induced by alcohol and other psychoactive substances)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +271,F05,"(delirium, not induced by alcohol and other psychoactive substances)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,3.2,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +272,F06,(other mental disorders due to brain damage and dysfunction and to physical disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +273,F07,"(personality and behavioural disorders due to brain disease, damage and dysfunction)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +274,F09,(unspecified organic or symptomatic mental disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +275,F10,(mental and behavioural disorders due to use of alcohol),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.7,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +276,F11,(mental and behavioural disorders due to use of opioids),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +277,F12,(mental and behavioural disorders due to use of cannabinoids),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +278,F13,(mental and behavioural disorders due to use of sedatives or hypnotics),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +279,F14,(mental and behavioural disorders due to use of cocaine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +280,F15,"(mental and behavioural disorders due to use of other stimulants, including caffeine)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +281,F16,(mental and behavioural disorders due to use of hallucinogens),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +282,F17,(mental and behavioural disorders due to use of tobacco),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +283,F18,(mental and behavioural disorders due to use of volatile solvents),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +284,F19,(mental and behavioural disorders due to multiple drug use and use of other psychoactive substances),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +285,F20,(schizophrenia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +286,F21,(schizotypal disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +287,F22,(persistent delusional disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +288,F23,(acute and transient psychotic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +289,F24,(induced delusional disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +290,F25,(schizoaffective disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +291,F28,(other nonorganic psychotic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +292,F29,(unspecified nonorganic psychosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +293,F30,(manic episode),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +294,F31,(bipolar affective disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +295,F32,(depressive episode),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.5,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +296,F33,(recurrent depressive disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +297,F34,(persistent mood [affective] disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +298,F38,(other mood [affective] disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +299,F39,(unspecified mood [affective] disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +300,F40,(phobic anxiety disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +301,F41,(other anxiety disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +302,F42,(obsessive-compulsive disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +303,F43,"(reaction to severe stress, and adjustment disorders)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +304,F44,(dissociative [conversion] disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +305,F45,(somatoform disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +306,F48,(other neurotic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +307,F50,(eating disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +308,F51,(nonorganic sleep disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +309,F52,"(sexual dysfunction, not caused by organic disorder or disease)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +310,F53,"(mental and behavioural disorders associated with the puerperium, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +311,F54,(psychological and behavioural factors associated with disorders or diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +312,F55,(abuse of non-dependence-producing substances),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +313,F59,(unspecified behavioural syndromes associated with physiological disturbances and physical factors),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +314,F60,(specific personality disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +315,F61,(mixed and other personality disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +316,F62,"(enduring personality changes, not attributable to brain damage and disease)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +317,F63,(habit and impulse disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +318,F64,(gender identity disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +319,F65,(disorders of sexual preference),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +320,F66,(psychological and behavioural disorders associated with sexual development and orientation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +321,F68,(other disorders of adult personality and behaviour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +322,F69,(unspecified disorder of adult personality and behaviour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +323,F70,(mild mental retardation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +324,F71,(moderate mental retardation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +325,F72,(severe mental retardation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +326,F78,(other mental retardation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +327,F79,(unspecified mental retardation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +328,F80,(specific developmental disorders of speech and language),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +329,F81,(specific developmental disorders of scholastic skills),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +330,F82,(specific developmental disorder of motor function),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +331,F83,(mixed specific developmental disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +332,F84,(pervasive developmental disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +333,F88,(other disorders of psychological development),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +334,F89,(unspecified disorder of psychological development),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +335,F90,(hyperkinetic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +336,F91,(conduct disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +337,F92,(mixed disorders of conduct and emotions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +338,F93,(emotional disorders with onset specific to childhood),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +339,F94,(disorders of social functioning with onset specific to childhood and adolescence),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +340,F95,(tic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +341,F98,(other behavioural and emotional disorders with onset usually occurring in childhood and adolescence),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +342,F99,"(mental disorder, not otherwise specified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +343,G00,"(bacterial meningitis, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +344,G01,(meningitis in bacterial diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +345,G02,(meningitis in other infectious and parasitic diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +346,G03,(meningitis due to other and unspecified causes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +347,G04,"(encephalitis, myelitis and encephalomyelitis)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +348,G05,"(encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +349,G06,(intracranial and intraspinal abscess and granuloma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +350,G07,(intracranial and intraspinal abscess and granuloma in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +351,G08,(intracranial and intraspinal phlebitis and thrombophlebitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +352,G09,(sequelae of inflammatory diseases of central nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +353,G10,(huntington's disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +354,G11,(hereditary ataxia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +355,G12,(spinal muscular atrophy and related syndromes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +356,G13,(systemic atrophies primarily affecting central nervous system in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +357,G14,(postpolio syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +358,G20,(parkinson's disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.8,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +359,G21,(secondary parkinsonism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +360,G22,(parkinsonism in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +361,G23,(other degenerative diseases of basal ganglia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +362,G24,(dystonia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +363,G25,(other extrapyramidal and movement disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +364,G30,(alzheimer's disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,4.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +365,G31,"(other degenerative diseases of nervous system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.2,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +366,G32,(other degenerative disorders of nervous system in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +367,G35,(multiple sclerosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +368,G36,(other acute disseminated demyelination),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +369,G37,(other demyelinating diseases of central nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +370,G40,(epilepsy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.5,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +371,G41,(status epilepticus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +372,G43,(migraine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +373,G44,(other headache syndromes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +374,G45,(transient cerebral ischaemic attacks and related syndromes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.2,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +375,G46,(vascular syndromes of brain in cerebrovascular diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +376,G47,(sleep disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +377,G50,(disorders of trigeminal nerve),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +378,G51,(facial nerve disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +379,G52,(disorders of other cranial nerves),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +380,G53,(cranial nerve disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +381,G54,(nerve root and plexus disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +382,G55,(nerve root and plexus compressions in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +383,G56,(mononeuropathies of upper limb),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +384,G57,(mononeuropathies of lower limb),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +385,G58,(other mononeuropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +386,G59,(mononeuropathy in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +387,G60,(hereditary and idiopathic neuropathy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +388,G61,(inflammatory polyneuropathy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +389,G62,(other polyneuropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +390,G63,(polyneuropathy in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +391,G64,(other disorders of peripheral nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +392,G70,(myasthenia gravis and other myoneural disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +393,G71,(primary disorders of muscles),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +394,G72,(other myopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +395,G73,(disorders of myoneural junction and muscle in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +396,G80,(infantile cerebral palsy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +397,G81,(hemiplegia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,4.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +398,G82,(paraplegia and tetraplegia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +399,G83,(other paralytic syndromes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +400,G90,(disorders of autonomic nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +401,G91,(hydrocephalus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +402,G92,(toxic encephalopathy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +403,G93,(other disorders of brain),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +404,G94,(other disorders of brain in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +405,G95,(other diseases of spinal cord),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +406,G96,(other disorders of central nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +407,G97,"(postprocedural disorders of nervous system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +408,G98,"(other disorders of nervous system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +409,G99,(other disorders of nervous system in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +410,H00,(hordeolum and chalazion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +411,H01,(other inflammation of eyelid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +412,H02,(other disorders of eyelid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +413,H03,(disorders of eyelid in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +414,H04,(disorders of lachrymal system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +415,H05,(disorders of orbit),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +416,H06,(disorders of lachrymal system and orbit in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +417,H10,(conjunctivitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +418,H11,(other disorders of conjunctiva),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +419,H13,(disorders of conjunctiva in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +420,H15,(disorders of sclera),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +421,H16,(keratitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +422,H17,(corneal scars and opacities),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +423,H18,(other disorders of cornea),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +424,H19,(disorders of sclera and cornea in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +425,H20,(iridocyclitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +426,H21,(other disorders of iris and ciliary body),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +427,H22,(disorders of iris and ciliary body in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +428,H25,(senile cataract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +429,H26,(other cataract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +430,H27,(other disorders of lens),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +431,H28,(cataract and other disorders of lens in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +432,H30,(chorioretinal inflammation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +433,H31,(other disorders of choroid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +434,H32,(chorioretinal disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +435,H33,(retinal detachments and breaks),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +436,H34,(retinal vascular occlusions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +437,H35,(other retinal disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +438,H36,(retinal disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +439,H40,(glaucoma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +440,H42,(glaucoma in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +441,H43,(disorders of vitreous body),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +442,H44,(disorders of globe),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +443,H45,(disorders of vitreous body and globe in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +444,H46,(optic neuritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +445,H47,(other disorders of optic [2nd] nerve and visual pathways),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +446,H48,(disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +447,H49,(paralytic strabismus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +448,H50,(other strabismus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +449,H51,(other disorders of binocular movement),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +450,H52,(disorders of refraction and accommodation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +451,H53,(visual disturbances),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +452,H54,(blindness and low vision),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.9,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +453,H55,(nystagmus and other irregular eye movements),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +454,H57,(other disorders of eye and adnexa),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +455,H58,(other disorders of eye and adnexa in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +456,H59,"(postprocedural disorders of eye and adnexa, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +457,H60,(otitis externa),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +458,H61,(other disorders of external ear),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +459,H62,(disorders of external ear in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +460,H65,(nonsuppurative otitis media),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +461,H66,(suppurative and unspecified otitis media),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +462,H67,(otitis media in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +463,H68,(eustachian salpingitis and obstruction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +464,H69,(other disorders of eustachian tube),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +465,H70,(mastoiditis and related conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +466,H71,(cholesteatoma of middle ear),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +467,H72,(perforation of tympanic membrane),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +468,H73,(other disorders of tympanic membrane),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +469,H74,(other disorders of middle ear and mastoid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +470,H75,(other disorders of middle ear and mastoid in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +471,H80,(otosclerosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +472,H81,(disorders of vestibular function),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +473,H82,(vertiginous syndromes in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +474,H83,(other diseases of inner ear),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +475,H90,(conductive and sensorineural hearing loss),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +476,H91,(other hearing loss),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.9,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +477,H92,(otalgia and effusion of ear),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +478,H93,"(other disorders of ear, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +479,H94,(other disorders of ear in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +480,H95,"(postprocedural disorders of ear and mastoid process, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +481,I00,(rheumatic fever without mention of heart involvement),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +482,I01,(rheumatic fever with heart involvement),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +483,I02,(rheumatic chorea),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +484,I05,(rheumatic mitral valve diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +485,I06,(rheumatic aortic valve diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +486,I07,(rheumatic tricuspid valve diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +487,I08,(multiple valve diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +488,I09,(other rheumatic heart diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +489,I10,(essential (primary) hypertension),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +490,I11,(hypertensive heart disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +491,I12,(hypertensive renal disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +492,I13,(hypertensive heart and renal disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +493,I15,(secondary hypertension),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +494,I20,(angina pectoris),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +495,I21,(acute myocardial infarction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +496,I22,(subsequent myocardial infarction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +497,I23,(certain current complications following acute myocardial infarction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +498,I24,(other acute ischaemic heart diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +499,I25,(chronic ischaemic heart disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +500,I26,(pulmonary embolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +501,I27,(other pulmonary heart diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +502,I28,(other diseases of pulmonary vessels),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +503,I30,(acute pericarditis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +504,I31,(other diseases of pericardium),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +505,I32,(pericarditis in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +506,I33,(acute and subacute endocarditis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +507,I34,(nonrheumatic mitral valve disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +508,I35,(nonrheumatic aortic valve disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +509,I36,(nonrheumatic tricuspid valve disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +510,I37,(pulmonary valve disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +511,I38,"(endocarditis, valve unspecified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +512,I39,(endocarditis and heart valve disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +513,I40,(acute myocarditis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +514,I41,(myocarditis in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +515,I42,(cardiomyopathy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +516,I43,(cardiomyopathy in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +517,I44,(atrioventricular and left bundle-branch block),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +518,I45,(other conduction disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +519,I46,(cardiac arrest),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +520,I47,(paroxysmal tachycardia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +521,I48,(atrial fibrillation and flutter),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +522,I49,(other cardiac arrhythmias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +523,I50,(heart failure),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +524,I51,(complications and ill-defined descriptions of heart disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +525,I52,(other heart disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +526,I60,(subarachnoid haemorrhage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +527,I61,(intracerebral haemorrhage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +528,I62,(other nontraumatic intracranial haemorrhage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +529,I63,(cerebral infarction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.8,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +530,I64,"(stroke, not specified as haemorrhage or infarction)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +531,I65,"(occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +532,I66,"(occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +533,I67,(other cerebrovascular diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.6,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +534,I68,(cerebrovascular disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +535,I69,(sequelae of cerebrovascular disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,3.7,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +536,I70,(atherosclerosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +537,I71,(aortic aneurysm and dissection),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +538,I72,(other aneurysm),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +539,I73,(other peripheral vascular diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +540,I74,(arterial embolism and thrombosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +541,I77,(other disorders of arteries and arterioles),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +542,I78,(diseases of capillaries),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +543,I79,"(disorders of arteries, arterioles and capillaries in diseases classified elsewhere)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +544,I80,(phlebitis and thrombophlebitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +545,I81,(portal vein thrombosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +546,I82,(other venous embolism and thrombosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +547,I83,(varicose veins of lower extremities),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +548,I84,(haemorrhoids),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +549,I85,(oesophageal varices),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +550,I86,(varicose veins of other sites),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +551,I87,(other disorders of veins),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +552,I88,(nonspecific lymphadenitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +553,I89,(other non-infective disorders of lymphatic vessels and lymph nodes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +554,I95,(hypotension),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.6,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +555,I97,"(postprocedural disorders of circulatory system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +556,I98,(other disorders of circulatory system in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +557,I99,(other and unspecified disorders of circulatory system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +558,J00,(acute nasopharyngitis [common cold]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +559,J01,(acute sinusitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +560,J02,(acute pharyngitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +561,J03,(acute tonsillitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +562,J04,(acute laryngitis and tracheitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +563,J05,(acute obstructive laryngitis [croup] and epiglottitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +564,J06,(acute upper respiratory infections of multiple and unspecified sites),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +565,J09,(influenza due to certain identified influenza virus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +566,J10,(influenza due to identified influenza virus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +567,J11,"(influenza, virus not identified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +568,J12,"(viral pneumonia, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +569,J13,(pneumonia due to streptococcus pneumoniae),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +570,J14,(pneumonia due to haemophilus influenzae),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +571,J15,"(bacterial pneumonia, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +572,J16,"(pneumonia due to other infectious organisms, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +573,J17,(pneumonia in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +574,J18,"(pneumonia, organism unspecified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.1,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +575,J20,(acute bronchitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +576,J21,(acute bronchiolitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +577,J22,(unspecified acute lower respiratory infection),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.7,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +578,J30,(vasomotor and allergic rhinitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +579,J31,"(chronic rhinitis, nasopharyngitis and pharyngitis)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +580,J32,(chronic sinusitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +581,J33,(nasal polyp),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +582,J34,(other disorders of nose and nasal sinuses),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +583,J35,(chronic diseases of tonsils and adenoids),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +584,J36,(peritonsillar abscess),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +585,J37,(chronic laryngitis and laryngotracheitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +586,J38,"(diseases of vocal cords and larynx, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +587,J39,(other diseases of upper respiratory tract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +588,J40,"(bronchitis, not specified as acute or chronic)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +589,J41,(simple and mucopurulent chronic bronchitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +590,J42,(unspecified chronic bronchitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +591,J43,(emphysema),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +592,J44,(other chronic obstructive pulmonary disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +593,J45,(asthma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +594,J46,(status asthmaticus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +595,J47,(bronchiectasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +596,J60,(coalworker's pneumoconiosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +597,J61,(pneumoconiosis due to asbestos and other mineral fibres),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +598,J62,(pneumoconiosis due to dust containing silica),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +599,J63,(pneumoconiosis due to other inorganic dusts),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +600,J64,(unspecified pneumoconiosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +601,J66,(airway disease due to specific organic dust),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +602,J67,(hypersensitivity pneumonitis due to organic dust),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +603,J68,"(respiratory conditions due to inhalation of chemicals, gases, fumes and vapours)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +604,J69,(pneumonitis due to solids and liquids),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +605,J70,(respiratory conditions due to other external agents),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +606,J80,(adult respiratory distress syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +607,J81,(pulmonary oedema),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +608,J82,"(pulmonary eosinophilia, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +609,J84,(other interstitial pulmonary diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +610,J85,(abscess of lung and mediastinum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +611,J86,(pyothorax),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +612,J90,"(pleural effusion, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +613,J91,(pleural effusion in conditions classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +614,J92,(pleural plaque),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +615,J93,(pneumothorax),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +616,J94,(other pleural conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +617,J95,"(postprocedural respiratory disorders, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +618,J96,"(respiratory failure, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.5,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +619,J98,(other respiratory disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +620,J99,(respiratory disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +621,K00,(disorders of tooth development and eruption),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +622,K01,(embedded and impacted teeth),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +623,K02,(dental caries),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +624,K03,(other diseases of hard tissues of teeth),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +625,K04,(diseases of pulp and periapical tissues),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +626,K05,(gingivitis and periodontal diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +627,K06,(other disorders of gingiva and edentulous alveolar ridge),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +628,K07,(dentofacial anomalies [including malocclusion]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +629,K08,(other disorders of teeth and supporting structures),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +630,K09,"(cysts of oral region, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +631,K10,(other diseases of jaws),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +632,K11,(diseases of salivary glands),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +633,K12,(stomatitis and related lesions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +634,K13,(other diseases of lip and oral mucosa),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +635,K14,(diseases of tongue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +636,K20,(oesophagitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +637,K21,(gastro-oesophageal reflux disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +638,K22,(other diseases of oesophagus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +639,K23,(disorders of oesophagus in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +640,K25,(gastric ulcer),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +641,K26,(duodenal ulcer),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.6,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +642,K27,"(peptic ulcer, site unspecified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +643,K28,(gastrojejunal ulcer),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +644,K29,(gastritis and duodenitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +645,K30,(dyspepsia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +646,K31,(other diseases of stomach and duodenum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +647,K35,(acute appendicitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +648,K36,(other appendicitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +649,K37,(unspecified appendicitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +650,K38,(other diseases of appendix),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +651,K40,(inguinal hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +652,K41,(femoral hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +653,K42,(umbilical hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +654,K43,(ventral hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +655,K44,(diaphragmatic hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +656,K45,(other abdominal hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +657,K46,(unspecified abdominal hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +658,K50,(crohn's disease [regional enteritis]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +659,K51,(ulcerative colitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +660,K52,(other non-infective gastro-enteritis and colitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.3,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +661,K55,(vascular disorders of intestine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +662,K56,(paralytic ileus and intestinal obstruction without hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +663,K57,(diverticular disease of intestine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +664,K58,(irritable bowel syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +665,K59,(other functional intestinal disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.8,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +666,K60,(fissure and fistula of anal and rectal regions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +667,K61,(abscess of anal and rectal regions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +668,K62,(other diseases of anus and rectum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +669,K63,(other diseases of intestine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +670,K64,(haemorrhoids and perianal venous thrombosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +671,K65,(peritonitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +672,K66,(other disorders of peritoneum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +673,K67,(disorders of peritoneum in infectious diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +674,K70,(alcoholic liver disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +675,K71,(toxic liver disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +676,K72,"(hepatic failure, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +677,K73,"(chronic hepatitis, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +678,K74,(fibrosis and cirrhosis of liver),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +679,K75,(other inflammatory liver diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +680,K76,(other diseases of liver),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +681,K77,(liver disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +682,K80,(cholelithiasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +683,K81,(cholecystitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +684,K82,(other diseases of gallbladder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +685,K83,(other diseases of biliary tract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +686,K85,(acute pancreatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +687,K86,(other diseases of pancreas),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +688,K87,"(disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +689,K90,(intestinal malabsorption),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +690,K91,"(postprocedural disorders of digestive system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +691,K92,(other diseases of digestive system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.8,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +692,K93,(disorders of other digestive organs in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +693,L00,(staphylococcal scalded skin syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +694,L01,(impetigo),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +695,L02,"(cutaneous abscess, furuncle and carbuncle)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +696,L03,(cellulitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +697,L04,(acute lymphadenitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +698,L05,(pilonidal cyst),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +699,L08,(other local infections of skin and subcutaneous tissue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +700,L10,(pemphigus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +701,L11,(other acantholytic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +702,L12,(pemphigoid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +703,L13,(other bullous disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +704,L14,(bullous disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +705,L20,(atopic dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +706,L21,(seborrhoeic dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +707,L22,(diaper [napkin] dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +708,L23,(allergic contact dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +709,L24,(irritant contact dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +710,L25,(unspecified contact dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +711,L26,(exfoliative dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +712,L27,(dermatitis due to substances taken internally),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +713,L28,(lichen simplex chronicus and prurigo),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +714,L29,(pruritus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +715,L30,(other dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +716,L40,(psoriasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +717,L41,(parapsoriasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +718,L42,(pityriasis rosea),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +719,L43,(lichen planus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +720,L44,(other papulosquamous disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +721,L50,(urticaria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +722,L51,(erythema multiforme),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +723,L52,(erythema nodosum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +724,L53,(other erythematous conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +725,L54,(erythema in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +726,L55,(sunburn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +727,L56,(other acute skin changes due to ultraviolet radiation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +728,L57,(skin changes due to chronic exposure to nonionising radiation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +729,L58,(radiodermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +730,L59,(other disorders of skin and subcutaneous tissue related to radiation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +731,L60,(nail disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +732,L62,(nail disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +733,L63,(alopecia areata),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +734,L64,(androgenic alopecia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +735,L65,(other nonscarring hair loss),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +736,L66,(cicatricial alopecia [scarring hair loss]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +737,L67,(hair colour and hair shaft abnormalities),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +738,L68,(hypertrichosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +739,L70,(acne),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +740,L71,(rosacea),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +741,L72,(follicular cysts of skin and subcutaneous tissue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +742,L73,(other follicular disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +743,L74,(eccrine sweat disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +744,L75,(apocrine sweat disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +745,L80,(vitiligo),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +746,L81,(other disorders of pigmentation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +747,L82,(seborrhoeic keratosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +748,L83,(acanthosis nigricans),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +749,L84,(corns and callosities),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +750,L85,(other epidermal thickening),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +751,L86,(keratoderma in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +752,L87,(transepidermal elimination disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +753,L88,(pyoderma gangrenosum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +754,L89,(decubitus ulcer),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.7,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +755,L90,(atrophic disorders of skin),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +756,L91,(hypertrophic disorders of skin),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +757,L92,(granulomatous disorders of skin and subcutaneous tissue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +758,L93,(lupus erythematosus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +759,L94,(other localised connective tissue disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +760,L95,"(vasculitis limited to skin, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +761,L97,"(ulcer of lower limb, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.6,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +762,L98,"(other disorders of skin and subcutaneous tissue, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +763,L99,(other disorders of skin and subcutaneous tissue in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +764,M00,(pyogenic arthritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +765,M01,(direct infections of joint in infectious and parasitic diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +766,M02,(reactive arthropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +767,M03,(postinfective and reactive arthropathies in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +768,M05,(seropositive rheumatoid arthritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +769,M06,(other rheumatoid arthritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +770,M07,(psoriatic and enteropathic arthropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +771,M08,(juvenile arthritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +772,M09,(juvenile arthritis in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +773,M10,(gout),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +774,M11,(other crystal arthropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +775,M12,(other specific arthropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +776,M13,(other arthritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +777,M14,(arthropathies in other diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +778,M15,(polyarthrosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +779,M16,(coxarthrosis [arthrosis of hip]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +780,M17,(gonarthrosis [arthrosis of knee]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +781,M18,(arthrosis of first carpometacarpal joint),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +782,M19,(other arthrosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.5,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +783,M20,(acquired deformities of fingers and toes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +784,M21,(other acquired deformities of limbs),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +785,M22,(disorders of patella),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +786,M23,(internal derangement of knee),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +787,M24,(other specific joint derangements),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +788,M25,"(other joint disorders, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.3,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +789,M30,(polyarteritis nodosa and related conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +790,M31,(other necrotising vasculopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +791,M32,(systemic lupus erythematosus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +792,M33,(dermatopolymyositis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +793,M34,(systemic sclerosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +794,M35,(other systemic involvement of connective tissue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +795,M36,(systemic disorders of connective tissue in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +796,M40,(kyphosis and lordosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +797,M41,(scoliosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.9,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +798,M42,(spinal osteochondrosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +799,M43,(other deforming dorsopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +800,M45,(ankylosing spondylitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +801,M46,(other inflammatory spondylopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +802,M47,(spondylosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +803,M48,(other spondylopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.5,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +804,M49,(spondylopathies in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +805,M50,(cervical disk disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +806,M51,(other intervertebral disk disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +807,M53,"(other dorsopathies, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +808,M54,(dorsalgia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +809,M60,(myositis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +810,M61,(calcification and ossification of muscle),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +811,M62,(other disorders of muscle),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +812,M63,(disorders of muscle in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +813,M65,(synovitis and tenosynovitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +814,M66,(spontaneous rupture of synovium and tendon),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +815,M67,(other disorders of synovium and tendon),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +816,M68,(disorders of synovium and tendon in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +817,M70,"(soft tissue disorders related to use, overuse and pressure)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +818,M71,(other bursopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +819,M72,(fibroblastic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +820,M73,(soft tissue disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +821,M75,(shoulder lesions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +822,M76,"(enthesopathies of lower limb, excluding foot)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +823,M77,(other enthesopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +824,M79,"(other soft tissue disorders, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.1,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +825,M80,(osteoporosis with pathological fracture),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.8,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +826,M81,(osteoporosis without pathological fracture),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +827,M82,(osteoporosis in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +828,M83,(adult osteomalacia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +829,M84,(disorders of continuity of bone),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +830,M85,(other disorders of bone density and structure),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +831,M86,(osteomyelitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +832,M87,(osteonecrosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +833,M88,(paget's disease of bone [osteitis deformans]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +834,M89,(other disorders of bone),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +835,M90,(osteopathies in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +836,M91,(juvenile osteochondrosis of hip and pelvis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +837,M92,(other juvenile osteochondrosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +838,M93,(other osteochondropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +839,M94,(other disorders of cartilage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +840,M95,(other acquired deformities of musculoskeletal system and connective tissue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +841,M96,"(postprocedural musculoskeletal disorders, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +842,M99,"(biomechanical lesions, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +843,N00,(acute nephritic syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +844,N01,(rapidly progressive nephritic syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +845,N02,(recurrent and persistent haematuria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +846,N03,(chronic nephritic syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +847,N04,(nephrotic syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +848,N05,(unspecified nephritic syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +849,N06,(isolated proteinuria with specified morphological lesion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +850,N07,"(hereditary nephropathy, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +851,N08,(glomerular disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +852,N10,(acute tubulo-interstitial nephritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +853,N11,(chronic tubulo-interstitial nephritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +854,N12,"(tubulo-interstitial nephritis, not specified as acute or chronic)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +855,N13,(obstructive and reflux uropathy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +856,N14,(drug- and heavy-metal-induced tubulo-interstitial and tubular conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +857,N15,(other renal tubulo-interstitial diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +858,N16,(renal tubulo-interstitial disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +859,N17,(acute renal failure),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.8,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +860,N18,(chronic renal failure),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +861,N19,(unspecified renal failure),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.6,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +862,N20,(calculus of kidney and ureter),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.7,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +863,N21,(calculus of lower urinary tract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +864,N22,(calculus of urinary tract in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +865,N23,(unspecified renal colic),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +866,N25,(disorders resulting from impaired renal tubular function),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +867,N26,(unspecified contracted kidney),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +868,N27,(small kidney of unknown cause),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +869,N28,"(other disorders of kidney and ureter, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.3,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +870,N29,(other disorders of kidney and ureter in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +871,N30,(cystitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +872,N31,"(neuromuscular dysfunction of bladder, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +873,N32,(other disorders of bladder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +874,N33,(bladder disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +875,N34,(urethritis and urethral syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +876,N35,(urethral stricture),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +877,N36,(other disorders of urethra),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +878,N37,(urethral disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +879,N39,(other disorders of urinary system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,3.2,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 +880,N40,(hyperplasia of prostate),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +881,N41,(inflammatory diseases of prostate),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +882,N42,(other disorders of prostate),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +883,N43,(hydrocele and spermatocele),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +884,N44,(torsion of testis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +885,N45,(orchitis and epididymitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +886,N46,(male infertility),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +887,N47,"(redundant prepuce, phimosis and paraphimosis)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +888,N48,(other disorders of penis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +889,N49,"(inflammatory disorders of male genital organs, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +890,N50,(other disorders of male genital organs),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +891,N51,(disorders of male genital organs in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +892,N60,(benign mammary dysplasia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +893,N61,(inflammatory disorders of breast),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +894,N62,(hypertrophy of breast),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +895,N63,(unspecified lump in breast),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +896,N64,(other disorders of breast),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +897,N70,(salpingitis and oophoritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +898,N71,"(inflammatory disease of uterus, except cervix)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +899,N72,(inflammatory disease of cervix uteri),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +900,N73,(other female pelvic inflammatory diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +901,N74,(female pelvic inflammatory disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +902,N75,(diseases of bartholin's gland),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +903,N76,(other inflammation of vagina and vulva),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +904,N77,(vulvovaginal ulceration and inflammation in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +905,N80,(endometriosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +906,N81,(female genital prolapse),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +907,N82,(fistulae involving female genital tract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +908,N83,"(noninflammatory disorders of ovary, fallopian tube and broad ligament)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +909,N84,(polyp of female genital tract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +910,N85,"(other noninflammatory disorders of uterus, except cervix)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +911,N86,(erosion and ectropion of cervix uteri),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +912,N87,(dysplasia of cervix uteri),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +913,N88,(other noninflammatory disorders of cervix uteri),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +914,N89,(other noninflammatory disorders of vagina),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +915,N90,(other noninflammatory disorders of vulva and perineum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +916,N91,"(absent, scanty and rare menstruation)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +917,N92,"(excessive, frequent and irregular menstruation)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +918,N93,(other abnormal uterine and vaginal bleeding),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +919,N94,(pain and other conditions associated with female genital organs and menstrual cycle),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +920,N95,(menopausal and other perimenopausal disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +921,N96,(habitual aborter),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +922,N97,(female infertility),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +923,N98,(complications associated with artificial fertilisation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +924,N99,"(postprocedural disorders of genito-urinary system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +925,O00,(ectopic pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +926,O01,(hydatidiform mole),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +927,O02,(other abnormal products of conception),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +928,O03,(spontaneous abortion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +929,O04,(medical abortion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +930,O05,(other abortion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +931,O06,(unspecified abortion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +932,O07,(failed attempted abortion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +933,O08,(complications following abortion and ectopic and molar pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +934,O10,"(pre-existing hypertension complicating pregnancy, childbirth and the puerperium)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +935,O11,(pre-existing hypertensive disorder with superimposed proteinuria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +936,O12,(gestational [pregnancy-induced] oedema and proteinuria without hypertension),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +937,O13,(gestational [pregnancy-induced] hypertension without significant proteinuria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +938,O14,(gestational [pregnancy-induced] hypertension with significant proteinuria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +939,O15,(eclampsia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +940,O16,(unspecified maternal hypertension),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +941,O20,(haemorrhage in early pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +942,O21,(excessive vomiting in pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +943,O22,(venous complications in pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +944,O23,(infections of genito-urinary tract in pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +945,O24,(diabetes mellitus in pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +946,O25,(malnutrition in pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +947,O26,(maternal care for other conditions predominantly related to pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +948,O28,(abnormal findings on antenatal screening of mother),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +949,O29,(complications of anaesthesia during pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +950,O30,(multiple gestation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +951,O31,(complications specific to multiple gestation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +952,O32,(maternal care for known or suspected malpresentation of foetus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +953,O33,(maternal care for known or suspected disproportion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +954,O34,(maternal care for known or suspected abnormality of pelvic organs),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +955,O35,(maternal care for known or suspected foetal abnormality and damage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +956,O36,(maternal care for other known or suspected foetal problems),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +957,O40,(polyhydramnios),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +958,O41,(other disorders of amniotic fluid and membranes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +959,O42,(premature rupture of membranes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +960,O43,(placental disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +961,O44,(placenta praevia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +962,O45,(premature separation of placenta [abruptio placentae]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +963,O46,"(antepartum haemorrhage, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +964,O47,(false labour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +965,O48,(prolonged pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +966,O60,(preterm delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +967,O61,(failed induction of labour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +968,O62,(abnormalities of forces of labour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +969,O63,(long labour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +970,O64,(obstructed labour due to malposition and malpresentation of foetus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +971,O65,(obstructed labour due to maternal pelvic abnormality),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +972,O66,(other obstructed labour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +973,O67,"(labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +974,O68,(labour and delivery complicated by foetal stress [distress]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +975,O69,(labour and delivery complicated by umbilical cord complications),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +976,O70,(perineal laceration during delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +977,O71,(other obstetric trauma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +978,O72,(postpartum haemorrhage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +979,O73,"(retained placenta and membranes, without haemorrhage)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +980,O74,(complications of anaesthesia during labour and delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +981,O75,"(other complications of labour and delivery, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +982,O80,(single spontaneous delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +983,O81,(single delivery by forceps and vacuum extractor),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +984,O82,(single delivery by caesarean section),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +985,O83,(other assisted single delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +986,O84,(multiple delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +987,O85,(puerperal sepsis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +988,O86,(other puerperal infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +989,O87,(venous complications in the puerperium),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +990,O88,(obstetric embolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +991,O89,(complications of anaesthesia during the puerperium),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +992,O90,"(complications of the puerperium, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +993,O91,(infections of breast associated with childbirth),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +994,O92,(other disorders of breast and lactation associated with childbirth),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +995,O94,"(sequelae of complication of pregnancy, childbirth and the puerperium)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +996,O96,(death from any obstetric cause occurring more than 42 days but less than one year after delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +997,O98,"(maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +998,O99,"(other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +999,P00,(foetus and newborn affected by maternal conditions that may be unrelated to present pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1000,P02,"(foetus and newborn affected by complications of placenta, cord and membranes)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1001,P03,(foetus and newborn affected by other complications of labour and delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1002,P04,(foetus and newborn affected by noxious influences transmitted via placenta or breast milk),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1003,P05,(slow foetal growth and foetal malnutrition),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1004,P07,"(disorders related to short gestation and low birth weight, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1005,P08,(disorders related to long gestation and high birth weight),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1006,P10,(intracranial laceration and haemorrhage due to birth injury),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1007,P11,(other birth injuries to central nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1008,P12,(birth injury to scalp),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1009,P13,(birth injury to skeleton),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1010,P14,(birth injury to peripheral nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1011,P15,(other birth injuries),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1012,P20,(intra-uterine hypoxia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1013,P21,(birth asphyxia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1014,P22,(respiratory distress of newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1015,P23,(congenital pneumonia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1016,P24,(neonatal aspiration syndromes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1017,P25,(interstitial emphysema and related conditions originating in the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1018,P26,(pulmonary haemorrhage originating in the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1019,P27,(chronic respiratory disease originating in the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1020,P28,(other respiratory conditions originating in the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1021,P29,(cardiovascular disorders originating in the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1022,P35,(congenital viral diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1023,P36,(bacterial sepsis of newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1024,P37,(other congenital infectious and parasitic diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1025,P38,(omphalitis of newborn with or without mild haemorrhage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1026,P39,(other infections specific to the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1027,P50,(foetal blood loss),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1028,P51,(umbilical haemorrhage of newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1029,P52,(intracranial nontraumatic haemorrhage of foetus and newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1030,P53,(haemorrhagic disease of foetus and newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1031,P54,(other neonatal haemorrhages),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1032,P55,(haemolytic disease of foetus and newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1033,P58,(neonatal jaundice due to other excessive haemolysis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1034,P59,(neonatal jaundice from other and unspecified causes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1035,P61,(other perinatal haematological disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1036,P70,(transitory disorders of carbohydrate metabolism specific to foetus and newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1037,P71,(transitory neonatal disorders of calcium and magnesium metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1038,P78,(other perinatal digestive system disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1039,P83,(other conditions of integument specific to foetus and newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1040,P91,(other disturbances of cerebral status of newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1041,P92,(feeding problems of newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1042,P94,(disorders of muscle tone of newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1043,P95,(foetal death of unspecified cause),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1044,P96,(other conditions originating in the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1045,Q00,(anencephaly and similar malformations),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1046,Q01,(encephalocele),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1047,Q02,(microcephaly),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1048,Q03,(congenital hydrocephalus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1049,Q04,(other congenital malformations of brain),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1050,Q05,(spina bifida),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1051,Q06,(other congenital malformations of spinal cord),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1052,Q07,(other congenital malformations of nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1053,Q10,"(congenital malformations of eyelid, lachrymal apparatus and orbit)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1054,Q11,"(anophthalmos, microphthalmos and macrophthalmos)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1055,Q12,(congenital lens malformations),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1056,Q13,(congenital malformations of anterior segment of eye),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1057,Q14,(congenital malformations of posterior segment of eye),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1058,Q15,(other congenital malformations of eye),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1059,Q16,(congenital malformations of ear causing impairment of hearing),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1060,Q17,(other congenital malformations of ear),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1061,Q18,(other congenital malformations of face and neck),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1062,Q20,(congenital malformations of cardiac chambers and connexions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1063,Q21,(congenital malformations of cardiac septa),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1064,Q22,(congenital malformations of pulmonary and tricuspid valves),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1065,Q23,(congenital malformations of aortic and mitral valves),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1066,Q24,(other congenital malformations of heart),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1067,Q25,(congenital malformations of great arteries),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1068,Q26,(congenital malformations of great veins),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1069,Q27,(other congenital malformations of peripheral vascular system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1070,Q28,(other congenital malformations of circulatory system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1071,Q30,(congenital malformations of nose),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1072,Q31,(congenital malformations of larynx),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1073,Q32,(congenital malformations of trachea and bronchus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1074,Q33,(congenital malformations of lung),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1075,Q34,(other congenital malformations of respiratory system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1076,Q35,(cleft palate),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1077,Q36,(cleft lip),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1078,Q37,(cleft palate with cleft lip),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1079,Q38,"(other congenital malformations of tongue, mouth and pharynx)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1080,Q39,(congenital malformations of oesophagus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1081,Q40,(other congenital malformations of upper alimentary tract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1082,Q41,"(congenital absence, atresia and stenosis of small intestine)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1083,Q42,"(congenital absence, atresia and stenosis of large intestine)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1084,Q43,(other congenital malformations of intestine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1085,Q44,"(congenital malformations of gallbladder, bile ducts and liver)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1086,Q45,(other congenital malformations of digestive system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1087,Q50,"(congenital malformations of ovaries, fallopian tubes and broad ligaments)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1088,Q51,(congenital malformations of uterus and cervix),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1089,Q52,(other congenital malformations of female genitalia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1090,Q53,(undescended testicle),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1091,Q54,(hypospadias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1092,Q55,(other congenital malformations of male genital organs),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1093,Q56,(indeterminate sex and pseudohermaphroditism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1094,Q60,(renal agenesis and other reduction defects of kidney),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1095,Q61,(cystic kidney disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1096,Q62,(congenital obstructive defects of renal pelvis and congenital malformations of ureter),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1097,Q63,(other congenital malformations of kidney),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1098,Q64,(other congenital malformations of urinary system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1099,Q65,(congenital deformities of hip),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1100,Q66,(congenital deformities of feet),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1101,Q67,"(congenital musculoskeletal deformities of head, face, spine and chest)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1102,Q68,(other congenital musculoskeletal deformities),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1103,Q69,(polydactyly),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1104,Q70,(syndactyly),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1105,Q71,(reduction defects of upper limb),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1106,Q72,(reduction defects of lower limb),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1107,Q73,(reduction defects of unspecified limb),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1108,Q74,(other congenital malformations of limb(s)),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1109,Q75,(other congenital malformations of skull and face bones),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1110,Q76,(congenital malformations of spine and bony thorax),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1111,Q77,(osteochondrodysplasia with defects of growth of tubular bones and spine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1112,Q78,(other osteochondrodysplasias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1113,Q79,"(congenital malformations of musculoskeletal system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1114,Q80,(congenital ichthyosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1115,Q81,(epidermolysis bullosa),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1116,Q82,(other congenital malformations of skin),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1117,Q83,(congenital malformations of breast),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1118,Q84,(other congenital malformations of integument),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1119,Q85,"(phakomatoses, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1120,Q86,"(congenital malformation syndromes due to known exogenous causes, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1121,Q87,(other specified congenital malformation syndromes affecting multiple systems),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1122,Q89,"(other congenital malformations, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1123,Q90,(down's syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1124,Q91,(edwards' syndrome and patau's syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1125,Q92,"(other trisomies and partial trisomies of the autosomes, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1126,Q93,"(monosomies and deletions from the autosomes, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1127,Q95,"(balanced rearrangements and structural markers, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1128,Q96,(turner's syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1129,Q97,"(other sex chromosome abnormalities, female phenotype, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1130,Q98,"(other sex chromosome abnormalities, male phenotype, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1131,Q99,"(other chromosome abnormalities, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1132,CXX,Unknown Cancer,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1133,C00,Malignant neoplasm of lip,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1134,C01,Malignant neoplasm of base of tongue,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1135,C02,Malignant neoplasm of other and unspecified parts of tongue,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1136,C03,Malignant neoplasm of gum,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1137,C04,Malignant neoplasm of floor of mouth,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1138,C05,Malignant neoplasm of palate,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1139,C06,Malignant neoplasm of other and unspecified parts of mouth,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1140,C07,Malignant neoplasm of parotid gland,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1141,C08,Malignant neoplasm of other and unspecified major salivary glands,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1142,C09,Malignant neoplasm of tonsil,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1143,C10,Malignant neoplasm of oropharynx,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1144,C11,Malignant neoplasm of nasopharynx,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1145,C12,Malignant neoplasm of pyriform sinus,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1146,C13,Malignant neoplasm of hypopharynx,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1147,C14,"Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1148,C15,Malignant neoplasm of oesophagus,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1149,C16,Malignant neoplasm of stomach,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1150,C17,Malignant neoplasm of small intestine,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1151,C18,Malignant neoplasm of colon,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1152,C19,Malignant neoplasm of rectosigmoid junction,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1153,C20,Malignant neoplasm of rectum,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1154,C21,Malignant neoplasm of anus and anal canal,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1155,C22,Malignant neoplasm of liver and intrahepatic bile ducts,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1156,C23,Malignant neoplasm of gallbladder,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1157,C24,Malignant neoplasm of other and unspecified parts of biliary tract,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1158,C25,Malignant neoplasm of pancreas,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1159,C26,Malignant neoplasm of other and ill-defined digestive organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1160,C30,Malignant neoplasm of nasal cavity and middle ear,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1161,C31,Malignant neoplasm of accessory sinuses,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1162,C32,Malignant neoplasm of larynx,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1163,C33,Malignant neoplasm of trachea,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1164,C34,Malignant neoplasm of bronchus and lung,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1165,C37,Malignant neoplasm of thymus,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1166,C38,"Malignant neoplasm of heart, mediastinum and pleura",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1167,C39,Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1168,C40,Malignant neoplasm of bone and articular cartilage of limbs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1169,C41,Malignant neoplasm of bone and articular cartilage of other and unspecified sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1170,C42,hematopoietic and reticuloendothelial systems (ICD-O-3 specific),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1171,C43,Malignant melanoma of skin,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1172,C44,Other malignant neoplasms of skin,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1173,C45,Mesothelioma,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1174,C46,Kaposi's sarcoma,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1175,C47,Malignant neoplasm of peripheral nerves and autonomic nervous system,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1176,C48,Malignant neoplasm of retroperitoneum and peritoneum,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1177,C49,Malignant neoplasm of other connective and soft tissue,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1178,C50,Malignant neoplasm of breast,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1179,C51,Malignant neoplasm of vulva,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1180,C52,Malignant neoplasm of vagina,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1181,C53,Malignant neoplasm of cervix uteri,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1182,C54,Malignant neoplasm of corpus uteri,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1183,C55,"Malignant neoplasm of uterus, part unspecified",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1184,C56,Malignant neoplasm of ovary,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1185,C57,Malignant neoplasm of other and unspecified female genital organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1186,C58,Malignant neoplasm of placenta,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1187,C60,Malignant neoplasm of penis,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1188,C61,Malignant neoplasm of prostate,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1189,C62,Malignant neoplasm of testis,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1190,C63,Malignant neoplasm of other and unspecified male genital organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1191,C64,"Malignant neoplasm of kidney, except renal pelvis",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1192,C65,Malignant neoplasm of renal pelvis,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1193,C66,Malignant neoplasm of ureter,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1194,C67,Malignant neoplasm of bladder,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1195,C68,Malignant neoplasm of other and unspecified urinary organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1196,C69,Malignant neoplasm of eye and adnexa,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1197,C70,Malignant neoplasm of meninges,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1198,C71,Malignant neoplasm of brain,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1199,C72,"Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1200,C73,Malignant neoplasm of thyroid gland,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1201,C74,Malignant neoplasm of adrenal gland,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1202,C75,Malignant neoplasm of other endocrine glands and related structures,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1203,C76,Malignant neoplasm of other and ill-defined sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1204,C77,Secondary and unspecified malignant neoplasm of lymph nodes,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1205,C78,Secondary malignant neoplasm of respiratory and digestive organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1206,C79,Secondary malignant neoplasm of other sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1207,C80,Malignant neoplasm without specification of site,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1208,C81,Hodgkin's disease,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1209,C82,Follicular [nodular] non-Hodgkin's lymphoma,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1210,C83,Diffuse non-Hodgkin's lymphoma,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1211,C84,Peripheral and cutaneous T-cell lymphomas,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1212,C85,Other and unspecified types of non-Hodgkin's lymphoma,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1213,C86,Other specified types of T/NK-cell lymphoma,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1214,C88,Malignant immunoproliferative diseases,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1215,C90,Multiple myeloma and malignant plasma cell neoplasms,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1216,C91,Lymphoid leukaemia,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1217,C92,Myeloid leukaemia,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1218,C93,Monocytic leukaemia,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1219,C94,Other leukaemias of specified cell type,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1220,C95,Leukaemia of unspecified cell type,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1221,C96,"Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1222,C97,Malignant neoplasms of independent (primary) multiple sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1223,D00,"Carcinoma in situ of oral cavity, oesophagus and stomach",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1224,D01,Carcinoma in situ of other and unspecified digestive organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1225,D02,Carcinoma in situ of middle ear and respiratory system,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1226,D03,Melanoma in situ,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1227,D04,Carcinoma in situ of skin,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1228,D05,Carcinoma in situ of breast,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1229,D06,Carcinoma in situ of cervix uteri,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1230,D07,Carcinoma in situ of other and unspecified genital organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1231,D09,Carcinoma in situ of other and unspecified sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1232,D10,Benign neoplasm of mouth and pharynx,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1233,D11,Benign neoplasm of major salivary glands,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1234,D12,"Benign neoplasm of colon, rectum, anus and anal canal",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1235,D13,Benign neoplasm of other and ill-defined parts of digestive system,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1236,D15,Benign neoplasm of other and unspecified intrathoracic organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1237,D16,Benign neoplasm of bone and articular cartilage,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1238,D18,"Haemangioma and lymphangioma, any site",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1239,D27,Benign neoplasm of ovary,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1240,D30,Benign neoplasm of urinary organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1241,D32,Benign neoplasm of meninges,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1242,D33,Benign neoplasm of brain and other parts of central nervous system,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1243,D34,Benign neoplasm of thyroid gland,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1244,D35,Benign neoplasm of other and unspecified endocrine glands,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1245,D36,Benign neoplasm of other and unspecified sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1246,D37,Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1247,D38,Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1248,D39,Neoplasm of uncertain or unknown behaviour of female genital organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1249,D40,Neoplasm of uncertain or unknown behaviour of male genital organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1250,D41,Neoplasm of uncertain or unknown behaviour of urinary organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1251,D42,Neoplasm of uncertain or unknown behaviour of meninges,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1252,D43,Neoplasm of uncertain or unknown behaviour of brain and central nervous system,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1253,D44,Neoplasm of uncertain or unknown behaviour of endocrine glands,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1254,D45,Polycythaemia vera,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1255,D46,Myelodysplastic syndromes,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1256,D47,"Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1257,D48,Neoplasm of uncertain or unknown behaviour of other and unspecified sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs +1258,DEATH,,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs diff --git a/uk_hfrs_missing_label_codes.csv b/uk_hfrs_missing_label_codes.csv new file mode 100644 index 0000000..3d176ee --- /dev/null +++ b/uk_hfrs_missing_label_codes.csv @@ -0,0 +1,53 @@ +hfrs_source_code,hfrs_weight,missing_reason,hfrs_source +R00,0.7,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R02,1.0,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R11,0.3,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R13,0.8,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R26,2.6,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R29,3.6,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R31,3.0,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R32,1.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R33,1.3,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R40,2.5,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R41,2.7,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R44,1.6,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R45,1.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R47,1.0,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R50,0.1,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R54,2.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R55,1.8,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R56,2.6,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R63,0.9,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R69,1.3,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R79,0.6,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +R94,1.4,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +S00,3.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +S01,1.1,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +S06,2.4,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +S09,1.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +S22,1.8,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +S32,1.4,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +S42,2.3,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +S51,0.5,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +S72,1.4,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +S80,2.0,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +T83,2.4,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +U80,0.8,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +W01,0.9,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +W06,1.1,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +W10,0.9,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +W18,2.1,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +W19,3.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +X59,1.5,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +Y84,0.7,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +Y95,1.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +Z22,1.7,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +Z50,2.1,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +Z60,1.8,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +Z73,0.6,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +Z74,1.1,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +Z75,2.0,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +Z87,1.5,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +Z91,0.5,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +Z93,1.0,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 +Z99,0.8,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2