From df6b45b95a62f2627068bea7601e07a4e8b63d6e Mon Sep 17 00:00:00 2001 From: Jiarui Li Date: Sat, 27 Jun 2026 10:53:55 +0800 Subject: [PATCH] Clarify all-future model interpretation --- all_future_model_interpretation.pdf | Bin 0 -> 127021 bytes all_future_model_interpretation.tex | 393 +++++++ build_organ_involvement_label_mapping.py | 157 --- build_uk_hfrs_label_mapping.py | 215 ---- burden_index.py | 407 ------- burden_index_method.tex | 161 --- burden_index_method_zh.tex | 142 --- compute_deephealth_indices_landmarks.py | 717 ------------ organ_involvement_label_mapping.csv | 1257 ---------------------- plot_deephealth_index_trajectories.py | 214 ---- uk_hfrs_label_mapping.csv | 1257 ---------------------- uk_hfrs_missing_label_codes.csv | 53 - 12 files changed, 393 insertions(+), 4580 deletions(-) create mode 100644 all_future_model_interpretation.pdf create mode 100644 all_future_model_interpretation.tex delete mode 100644 build_organ_involvement_label_mapping.py delete mode 100644 build_uk_hfrs_label_mapping.py delete mode 100644 burden_index.py delete mode 100644 burden_index_method.tex delete mode 100644 burden_index_method_zh.tex delete mode 100644 compute_deephealth_indices_landmarks.py delete mode 100644 organ_involvement_label_mapping.csv delete mode 100644 plot_deephealth_index_trajectories.py delete mode 100644 uk_hfrs_label_mapping.csv delete mode 100644 uk_hfrs_missing_label_codes.csv diff --git a/all_future_model_interpretation.pdf b/all_future_model_interpretation.pdf new file mode 100644 index 0000000000000000000000000000000000000000..5f9cb8f23551592208929d96642b43efd7e28be8 GIT binary patch literal 127021 zcma&sV~;Lev^D5mcI~ol+qP}nwryK?*|u$Smu=ftKb>^ar_=9;ldR0FtRJv)Wz0dU zARXb#OYgLyTT8XtMdkeVIe-WI(-aQ+wu?jOKT@`Pa4H|J--Fltv4Llk z*$?jTq5F42cD;We;~Mn*uJh~OB&O|6Q;*=_RU^hRpo)>qL-QT;l@|erZ;oEv+$K~H zD#-1R`&A5sCcg_?Z?Q;1w7{d)1=JvrdVv6b;n~x=9%%Hx^0#lyf~%=SK&YyKuiyL4 z^D9IE<%bK0P_ECtS4UJSW6BTMG(t;VuUn6SBLG;5RR%plvT2%G$Lu!Nm9NGezZUGo zWqxsAp%jU5VV}4dDiJ@9Ql3sk%y91gVuh2^<6^)zO4$u;ZUDvRU)5;0C5Y$m@bPyU z3*kRMHQA#cvL{ziL-6DNVo0Fop}nU)G2QA*umx^432H*8k~28tAw&9S>_oB{MR`W- z2vX5R(CJ3;7g$s^+wL26DPDi41!4E&QD*B43q^SZ2RP-s{K~+%94e*vxHI4KO05)v z+c!_+EDh^P6SYu_DAde+Dlq(4j+>N_tn%^{O*7}iz6PbfP|Xx|SHdH!Y=g*YAE<`; zt#t~Hc)g5a{9Hee-ZrD~pQL5|gbpx8a(85vkl0F@P66_lNobn~L=epS`#gwM(Ye-twNo@OXBKkkKXNW`!FkbCsyyF8w z=x=#q$R-`eY)Bi=wM9x2;t#m{WIGof0J&E*d0y3GITz2^nLSP0N$8dk@7cg!W^ob@F+s6LoJYu4IH z;UHQcB`<`9_@{r5-+ng1N#F;id&fCllAgCx#W&5XS=EuoO3aTcUIu@&203hru;)kV+9Fw6ZP4|=}u%< zNaI8j5;{h-Yfz9D$yw62O}o&0Oe1TZ=-to|K;qe4z-OyfI2m&@vsCqK>@KJQXjsnY zCMxoFrMiwQ4*yckD-~2b*jp+I7^r5>npnZx67V~!1-f#&ZPSU|nNqV?EbEr7h2eHe zs36K{5AH`e=WS%Y4M>i_est5ZU06*HQnA?SE2?hMqfU} zO{tWm@&lo@v7VfT*9O$WRnO@1Rb6ynGBt2@YdZ|t@ts`6)(NN7XFoo^oLbI}=rAz| zwuy)a_rum9Le$T)Uw(+7Zj^zm?^F?UVVJ@1Ua78dF>BeUF!pPYG$`ocPphdw-zAWN zH)a$lbuC>ZD~va`7EsfG9<7sp5XV{dfN>0`YzQ#({vgIJw3r*kcNp}JpX0(+7-r-^ zA5$VWuFnXGH+l7zZ`uVEtvMJf5hUN&y(~j0Ur*CLS)g~PcG(MT4@GAeVU_d9L|DwKHg=%kkohHmrqy;gkFQ(T$s|6YI;nxAGj(F zfk$D2c)3zWF|Qd3{vwVX%g34Xk0(j#&fS6#V9ccaen5l}p zx*GVHAOww1lge%!@!69doYArZe}JuMxlZ%fMuns8f7Q5F5i+PAuXJ||%Esc85(q*^ z%(UA$xw2JH6SC%bZh7@h+$vRDkr_dmA_j_H?Jq^G_l!-gT&yiR@ssE>j9$@UJzjLC z_Hv4jz)jR3)3+-6{eBF9V=t-C;}&?)`jSX5@@UZAb&f}rL;RIP)DB0iCmBL81@__F zpzLfW)_*zD6%%F2r=xRM@B_ZR0e*y+bv*Xl`6ozXHs*p{t_3SyQlzUKv^mQ(fISql z1cwazP-7TmRHv#_L<(2o&0w^#2Toj?BlR!oLZKv!F?PgdVHEKOOWf?J=sA_)wR|S! zUM7Un7?xur3$29L9taGR1s3c^q*$xQEmwnug8El#?#PkvE0qwFqGe>U9`^~uy|#MDVSJlwE& z#RUwPgfa@e>Bt`ljnH|IbXJ@m#sc)kz1^N&10UOAZ+(H;^-mob>h zzOug}R^e5A#bc9f^@UjfN`Jr3xHevCGpN)y)8x`+cjK>_1=G{gi$ilb#W#5 zG!L^K%Xq1?CPSCH+5cDpROTG4k8Jf?Wt?MIKK4L2fyL>+`eJ# ztW0HZ$gwGN6JM+?KM(esAC>*FsQ#U6mR{pIw#4m_%C7MbuAm2jjymfHP+Fx)xFDLf z9X8d`T=>CJ-7A|K-rCxt`%o33NHg?(I${pqUJnf}f0EBZANTv!6T>Xu*=a_Rci%$8 z?~8GN5z-8R()>49bEHAD1iPwG{|;-bLabb?|Jqu^9i2>j&VQ{Tu_t}*a98Tc^*7pmMa%Wtk8QrQqffm{{+qGf zv|p>D*^$mXBn$uB6(N4C@Jn!*F7aIcPp0Vx1#+{bE51xCF}c7Z`1Fl$;x~hSx!t@KA}y7)z_OW}|Gq{7cO>@$CMz8|BE z!b-kAUL0Ny`U4x@;{GZ-|0l%i-`ss@Q#+IYhiCuY{%_DRGySh*$IQs^KV`SAC0U0p ziqQK=9k%HW!M?rB&B#Z97Kwd;DjWv4%Ol;9uGRZd zxv|KfoWb#foDB9gS9bd9@yh(ulhx~=+50ZJCh2g}fxftiiXS|P&CRQ;hsU|q z2}w7E93K)R>}C6UA-e0}#*J~=M!WP_2$Q_z)scfBU1IEE62h;84!xPZ*cXz(?0}8ik7S(*ESr(`!#Z1aP-oHIg4FyyM%>#?FpTY831L#{t zhzY1r6$pYgQwg#(6ku6^U!^+K)ndBX+v|%1$}JXafN}3p5M=t1Pe({`9Ht*;PG}{R zPc6Q1v|C|H5|6p72U=%*%2CP4TnSA75aAH zNbzroC^J%$6cpq%MlueKSUe#?OoxUs#(-1QYV8aP$>U!uTmC@kE2P%II6vPpC}9w~ zXAL1Kqzq&droIuO4Zi?Q>!b&#L&2Z3?7Rnh{8J(MRE#S7k&c z{u^}xwpSG;r^LcdleS^p6sEA|+JuB;kWC^^N^TmtsGareWYi%XfZ~deUfOKlRERLK zlQ0GLbQg$h1iWuOGb#L<$|=TNON_RJHjv%EKEKJ*i9@lO!^MkUiz zvw;DQBM(wdl3Igg%>lz zm;u}}MrDW)wFwVR2abPhNSd*jb&pX}^8;GTN+SNi6iw^6_(n~RijS4jmltbj4B%m} z%-M8qelYL8VL5gcDO-yK_a}BE4>|TfDfDmR9-zDf4G8v|)iBlM)2s)&pp*@#u89lZ z3q?Z8f~6+AEqjt8cWit-7?*J~Of^;kG29$+)m)Mvb02-u{1dR`FxS6UqpdzmU#>=A3j?;>7 zgSIElZ*Da;2oOCLHG63jy;m+b6q(HDvIWM`Bs#50NM5tptGK)Eyk&66e+h!12Dhgo zM6ArJttF2PFhnqinMFdlkurW@p=A6^LD{McTOu+gwaNNQppkZG4`5iuU=KyUhJ;OqY(lsSI`z$#^CuBae{#%(z(g1?sL`Oo5tt!a3BQ)VP}z z^jUGXW2np7d0vB`B)QydY7CU$HMm)+X1DnvaRpQ6-Zu($F6LI+drI1W&Nm&dUv=eF zUNV$4HNX-|cN2G4K+e#ZXrQF=@c-CxaaN zMt_AKC;p&m7D&H>xkB-$g`WR4H2fh$dkOR^BqQ#(S;Rt*$6qLp{KdG&d95aR0+2Qh zx`7ciJ3({eo@4r9%wfFjk^Ld#SqBlj6jxU<0UUJC4=Oj+h|DD(vzzoHEV0r( zXqQxC;kYSg4*EMrh)3PEdNksK7684^?QwB@r7g|*=f1+g7XA5VAWnJ{lDcEB3k-25 zwoII=UnC-G$Xm>Sb-_Ra5 z;)5ZcqkkK0J{eoTIbpfSM6X;dPO<*)ny-u7NJA&mB?!Xb86JKu5#4}BWPb~b(Ocn6 z#EJ3nh8Vy7fDzR{@D;~sHZH?^hjH=WWuhnC8wGW%*>E$bOQ%|^x{+7WTL#22-dS7q`a#nMO zr&Y{3e7Q{&4ov&+H(sf*d`yG+rIk{F1jgHpBC43eFOP%o%Toa&@^@(fNbU+g0e8?;_fY|ZD22ypGR*8zogkgD`a>e|Goz%}w^&jzHks~xQY=^X@K5$~p;!OyMI;~Go_@YOy1Z6F zwR;&@5MNUB%lRZu@|Wd&!c`d4UC{2_7e|GOs$LQmT=gV~e2}}ohs=V3YG>my)%lA; znGa=AKyESTnfG$SwFTQ<8;Pl`IYV}|r74ofxu`4SOqk|bi>gpKmglt`kd#NZ2B1nSM zLLz!+bwe;x%0CEEO7dp9_qUTz2qZ;@Nyu=3JW-!iKsZ>p|KrRM$v6R+g>Eox`g$=2 z`F`q%Jb8?Z=B+$W3!evK&vcNU1uDFlh9%c0+CBju8a;vJ{!zvUSEuRlXr#zU?#q(0L0Nq+4ZPue+P7LyGv8MkaObx7n-)Sp8~ z>KI5b>OEBC<1MUfWT#SYnK~tp8ca+iNk^Q?jH5uym9qO-%6gQUU47I%jZ*-oihA3o zLn%IGKTkj-(<#g%*x%Hcdt6-%eL}KlHNYTh<$+YEYvH#I%B)*zujvL_r^A#QU}Ide zevxSs3M9yx96oiJky(xEKEZ;Pfw>ipc|cVtS8Q*5E#lo-8d@&k;;ciT$os0a&xE>y zPvj-5g7MZFi+Oaz4F=HEMN49;7wfgTr6OZB9+BV1q`<0U7J^p5O~5M@N0nVgp4c^moQ>T`dIsX=5$ zaH3JXmaVCMVn|?S1Cq!~a^`3ju33nR$4Qqa?j5b=6!>jjDjr>ah?E7>|0@@E5y^V642A7uriu*5IjK_ao2wSyaSOss!8)7Zu; zqX`_6Qrx8g&Muhk47TY-X0wPN+007-j2(TlyP)xjgAIKm5q8{-Wg44y%GPe^Dl{I{$$Gf-qf*>QBrci7-CbrU zq?^Yep!;M(8ofp#e%YGioE8*&6$6s43270wPNzWoctfwgAXoq^iyP&AGYmTm%)dOp z*sF~n9 zPdP__gi%wYH7OfExy3G8tB=ZHOnT@}5VhPo9J5OUKbr0cy5oSj7J7mbuP42a#&3 z#?8C_3i#`_djhwgOZC0izCbi(`Wbps9fmzUG{;-PRb3uvURFZPi5~e_Kd5^Q2uz%> zqn){OXT!+)f(&?5Q=X`Hz|Vb+1pTftnG{`p!N^owu+s+A%(BOd33>~%Bs9sycq5^Y zIXu|S$x@ft-Ki9Da3=XLkHt8D^U_Dm;%>cq?$f0F4vYO~|e=}aUR$-RF!8EML%SrXPgU+@fN*;s5iA`*Edl#ObboU5f{g! z+uh4wrZ_OxzLhnl`fK@G`R>$)?ywoW$}v03uu-Syqv~V?DwmqpjCTxJB1T3@D*cH+R_Z}N%*p0nV|Ny-=M{tHP_6*< z2HYOG6lUdrRx&fzB--8@G870<1W3Z+uCQ%rYhZ6Tpk`=M3a_(RR1jCbZ!N=Hv>5A( zGu2bDDiqUc-CJoshZk+3I&un#5XF=$Ab#l~n?Rm!a(yFo8dUd7- zG~t2e8Ded~^M+0JN6c;Q6%BH9n-i=7y325|y{uif#D@|wZryfTklA2kU*{guwDPlt z=s9-y?0YL(>pl?2tfiIKY*lu>u4xnZF1xfBB(;@Zd46jm&;}g!cV6ae1G!hf7gC(640ly1l;k?jPX3A87yI&ae05hp|2h|3srGqRFW#=%LB}zy6+@ zz5Zx}Gi~_#KkzD(PE_Y)*RTlYREN#krzHw*S22#sut^l5aexb}?9A$h^r}{6hd47B zfd*(p6d(1rss_H;QvGOzmEyilRWOWZByg}VQ6kx*htyuugD0N(b4(4oV_eazePtFt zOPR8UME|N5Wa3iJ4Q1xtz7hd&bkutdWH8B8kK)&RUMyDVV`XMP^~*HtLYKL> zVHCVWRn=VQ6*0eEZmr-2QD0l9>%>r~H*-@@$!%y-bzla9G)w%EW2*0?VoGd@hxhn5 zqlK$&sb=cMQrVf$HUv|z3ru`6)NEu{Lzm3OgPH~-% zP_M2Rtl$B3uZT!CVFp$w%qt1*Au zT60#chORFj)vy3%n6}1h&srELtR$k=HF=(ttz)bad zKu*-0V3>639PnGX0_I`^e8~)`DbZPx+RWhwnVT;EGI3{EC^_5RIxBE=a@1y?x`CKK zgn}2X4By0rYncZ3F~xb#YaE6_3TfzMJ8p%phcxxMj;^MJGS>HhBcbdeQkkI zVNYqsJ&D6BoIuTxJZ<4j(8_8zGn3hPQoDJP6j3In^;ku3f#iDIeYyeX8LV8)b|Cjv zW2;t#o$2VE!{g(nn!Fp6-0IxhkW6@=Q9|Zy$#}SxJLJA9${p;wVXcauUiZK_|G0z{ z__W86X*;t)2a0fqaAuyuP1DF3@yedH5xKx;AmV~V)(`{&MR7EO7w0o$Y!yTGE;)O& zx1kzrvatXF_rvvxx}rB)nNTaX+7X}B#bd7Q>9MaTl$}F(;ah_-ZZ$;>(@Fk`A|_a7 zCt}jdukfJZSC4#at?V8I>Q4%<8GeW~N4G9Q)2@o~I^4=8>X}(zdRw7sMQ}5Tou}b= zV3gm6!bMxu=L$5fOd&49Ws#BQLSV?dNK__PN~XUzAa{awJ&$W(zKrzCA)gqd^%_2^L;!XqdY$+z+=lJ*uLKo3_h3FEDo)8`F+1+!AH;eN6 z^r3WamVFruZDOxOi{S$yW=dkI??223MP(8XUw8XM1aGj)F`Z~|Oa~s5T8zGj6|Q*a zZmFV~J$$nGe$C^xgUJV&R?_VhDq8nrTn_>l%!;~88Dy=arX5^>F ziyD&(Ia?z7vIxpDeaAzrT9v@|ca++-VKx#QvB$lHLUe?slA8plnYB4FnK1?g3X{mo zj7|?_c(`_?-r27Y8%4;KkW+_XKK5lPijAhN5uN3q0ao>w3n7wVIm-3r&d@JUbBUiH zP#OiFUM^G-YvO(o6*zx@inv{NiQDhU_YW-iz9H$98WJIUu^jvBLMVi?7}JYO;4UPV zlQ~YQu?gW%Ka?&!nKRvRzKVIyZ`o2ra>CcLFaH2#)Q2c6ef9fLqrmd^`9$$^6D+b z1dPLR^UBoVY%&3k9{vlP=n~HFGeh zb6@8(@UWl&&5A*OO-WQZHX;!H)XkC#C_g^I`Hd$+r-Bhc>OxlK7$9g<_luH7Jr(5}pUv%eG-JK2T`$4JFZiO$ zs&h7kyCQnm(h2#ZNzfeiQ>yq>Dep~>$pOXjLt(~e6Zs5ixPjz3EPWoKPKIN7JnIc? z#dHgmXV$ao#`FNarkvu|2oJi~e{(Iyh}DMEMp%$Tk%MRznXRl{xW-3o>)Cx6wsfUO ze>hj5)TDeoqm~rbZ~n@#*S6 zxE|GNQf-}}9qnWlRVj8;u9S<(j@l4-`KSkKs&HF>hD~#1bL~!)fY53)9j`z7srY+% zQaK+AvgW9Ko^E{Fhw@5sgs~&c6vs}nBcwtm2ZG*N>1M~IZhEh`63ao9;^|K9^z2v| z2N?9}zK(vzsXe+|vtp*!>(SID>{Tq6pH0DZRz-Ot$fj|Ja6lx8D~ymEUWsQ& z#V@!Wk{?q@mQLo~G+F3_1(s6<7|qzKM1?5KDr_FuAAade#-@t-m(t#^bF+5VWrOPv z`>x~}DO7z@@Jm{!s6420B3_KXf-Q4I?y)P|b7<>NL5|J|^h!k3HfyT))ZUTCaw?qI zh-Bxym7}~xV(P-BN-YHqOR8f@m>{Kvn8_;9Ji_`NF584H;|Sz2gyJByf{)zR_{gB< zC`Pi$@TGw9*AREmc203)b@V(t2lF)k(AShZs>iiqHc�KX2pzz_gLwTK*q^%KX2| z_ZT_Jn(Hxpv6;kye4l5jU*42OX4-|l@22A>r1I|JcSSYhEbd93v*J0zD4=U&T8$Hba(WBg))Dd|g3G&*PR+bUQ1SiW zHo0vvo1@BXyQ5KvShKy&M(b0Jv5<#cW_zOE?6>9y2CI8*>sq3Nhmc2HjH&K)^bc39 z#L1rOlNV3aUbVOqUY2yx&tm}&C*5JqLf5Hd-pvg)OtcZ>AtAqiJAab%;}BgL$}w?z z#MUnU`e#?)idjj%&)wnpt<~6_lr;eVFxjk@mTD5L;{wCfJig^Q0c&SvsCBSHvH!(J za3`X6p49GBn=0{JCufR^z!c{_-HPKrO^?WtFd)=McPOv`Pl$W~{#fopM~_(TY4y-F+VhIp0n z;ZvlbTPy0hfD3t%{8F-Q54;?|iZCAVT*&@S`Ua`Esc-e;ciMI*8=$WJl=QEnkDy3$ z#d2B|R5oZ$#!YW)5sQFcg-6z`wf^CETKE1DHX;IaBz{1gdjflm%8Z^2ipV`Svt>An%OshALO-RFe zi|N|2Y_SwH4ZK)Ha4SsL=-#_2^+}=>T+j$3w|C34a}44#Aad5AB|vFW4kh9utvFRD zFpgtfC%9|+t$){{0Ni6>?xxs#vBWcPs@u?x)-eAc@rf8*&cishjVaIJ6kx>!cE)b_ z34C}b!Ntx%5F2Co51g$Om^551VV+I($XJdEcldU(YnU=^5kc$gd&;r19Q(=DrqyPE za>2EIfNao|ikrPkFHVus_)1Kqf6ZsQ356)osp+>J0y4kiZgyLOf*z{r4uLHU{Uv-h z={?)6Q&HkD|Nf15r4w%9MO3blUX8o#T&YrMn`$LC&V;gUT!#8WdUVLE(keE+m3gP2 zF~@*&MJu7z9g)W9Wi2ViBvjOb!l8{CsRG9&w`4P&;3gF($f?r!Iz6wh z<$SD=XsoP}_#3OpRDcl_rHfVLT@BbIopyq_jW8#L51pWRB;g2>N*bR^CeTH8n$t=bb(X1 z%I}FE?ixIYm?G8TjUEiC2>EQ-lWe&o6DD(D_=SI>H{VUTxN!yaC<<2n!v{n>mzui* z8o`eS?0_h&CV&d)C_xEaiJ;BPF-%j>vI2%&vaATON=BbBsMjFjpyp<`n4iMPyN#ns zNnl=OjrdB@1e7{kG;58rh)_0ecTy73E7p{#`V_ywxY4Uq3WML-;amQOhQ800D0wA- zvydnEwV%S(#WX}2=^X9$Sw(_XFAyk>Bo!A2`S(|mDT<$Y$uNzapVH3C(ZPbTnsyx$sZP(xZZAm_y9!vsE$McnqW6X^~LDmfe z`YP%&W)a}0157*OW7XKHriK{H87_Rk?UFUZ)pcup9b25A`bq?yZ>|2N-Q%8k$6*;6 zUG!YI95&tAx%iI&C8tcHnt16nJ0eYB8Go)j`eIDF&te0 zO}JrQubkX2%eT)Y@GkrEdNcn@i6?0Mnu+4%QsBY~vGX;2DMy*XX-%1f0)WBps65B4 zo1v>|e;nQZ#S5eA6RKa1t+!*2A2=0*di#?7-iLS`P8eAYbxZWA)@{jV(E#lF5OMLyMfW@V;F zt*htj%~nuL^foVKh?ljrV|4e??%OEWhI-vR{X7EVyh$@do(%EvB?78 z%{t?gYCzP6oKj*no2$F*G4l*c7Sf)_zyg=hYQ>?U+mPSBkkYKxBzx{4)ZDLHdb%8PA@Hz)hNn>qZK zmOQrFwcuvSGuL=jWsGEL3|ytK=SjpKJ=<9&IfkKl1e8db5D}Y z?8Gtd`M{PlYuG3idaeIzzo;md5%f&X{f@E$g^vf3Ic{RgzdCe_k2iP3Ycs%fAi)&6 z6zT8h!?THi*SkQ<_a!2XJ!DSRx4D*)2!DMl_jH?xyG4RXUP>8a7NO7Y!sIS&wysMw zWk;K7VW}9#fsZqZq=e6nzM{V+*LTITvV*I&5oeU5^uxi$IXf*=)^tp%;B0dK73ad# zaOu`+jO^v;{_aqP_<)2|okQX3zCM4C5Qo*}7`26h)x{^nSj>Oq>3;ey49-Kz!O{l) z$-_}P-)+zbA&J>JCQD{vCUW{K4`5`nKXh-wvKb`qsIkDE{%k`e$kE(7LijIg)(#f2 z54ckUf{d6h7qzRh7PaakX1#@+fh%ZWqiBJXO5GW3?$lS(#cn+OJiyvb8Xdpkk+HIW zkl&-Q|LfWQiv|h`!ISkeO(l7yTy$5`10;BiFx>>Qqz;cH-a=Tgq$uwTqf-g(op&Ew zzF;=hO4&#AoFfXr*5nUF+&-R&rD%juw5hIWMc%b(!crcI+<^X+wqh$Osh!qxZQyEJ zW&*~#58Y%Z)caC)%v~q0eJkxQUzG`Q?bqz6bZ<6mvMJ2nmuOm!(sE+MhE~ZhPl|Ea zH-IUD>$(8;FA(N@m~493c!#!4wP)RHzz%Y4cH;8zvJbZr5loV%5A(v?pVxcaO2l~% z(6N`4nT!U|ilhp7zF2r=pxx%HF_;EM2d%}>&p%m!l*}a8JEOGmKm*VCC|0LTd^#w{ z5C-*g3lxV-NcZb$*a-KDvJJV|!PKwFs7d&`HyDh|eJj@3O);4C`x?=X*9XJs5T9Nm zrV*9^LD?OQcQw2v5cMEd2HuLVxq;t_iH7wUz)tmwjx*$WG~U#7?rs+Ciu-s-W%E@& z4@rfkF#1%R@bkpAgtPM1CHOMaU{!Lvm@2SY|FR{e@5QWnh22d!8IXOumUxSEdW;x2 z=>zEgdYnWKd?ORXQ?X=dVLK5t-VFBY6q2=9QP^GAVk?e0I5@C6mpTz{oTvh z?;_935E?8-*%1?r?jRF!j}N++MIk{?j!fjfpoAX8v&nvqig92`V63($%Duf>8&;t6 z+i~n017E|6jR(ox#<;0I&+f*va7ui6q%kDPWjVQi#!+REp@AHK=TjhHhyi1xlim9~ zeijm?1U|^=7xh_B#=K7zC9b>$wA)xgx}eYRt){Ppt1ls)LRqF+s|dU8Ue15<0rHHW zRJBRil}F>Xro2AdMT?KL=3iAVqkPYUr&>LtJ=<25dKSx_*y%dSsS~Uu&!h46gs}(H zwT$oR*;ZDsT9go^D=ndIBved^j>d~#y|2{2J_@=WIJq&Uq#Gkz549ic}PDA+c|2&1>pNd zr%&OHG*Y2?tf(}r(vCEFk+-ayF)gl`S?$VfbDc-rfPTdtm#Zn$(z4ZhQLA|is4%(0 zZVY{~op7^ROq{_#_IP(a=FC4sdH1|5Qupm_8|fR{q@gZj_sy3=bH?3XxoK+*_LUD5 z$)O&Cc3$^@d1A84V((Uq`E8bjK2d?2D!Mz61sRk5k6id8$(^*3Kqhyj_IeORDe27?xx+m3t$ z6hssVXo%POLJlw}qEJ|lj2rA%3sZ+h9Y0e$0zTU+JK(puR&WJectRY>DOH^IVtT)b2*Q_M+=tu3~R$HZg|*hwiT@ld|hIhuE^Yg|{G4_>s(? zQ*~jTMRW>%E_4W{s!MkZ$v}bA{+Zfy{7qAO9Yn%RcQZPA)F7s9ib54gOVPH}AN<&v zc3!t7?s}PS>68+SGnhTt+9^M4)`kxNR1cZvCfPNRiTSF3}m!29{vcj%Lj(SmlWgh;dhst0CQqA)vay z5QxVz@g(cV0>M+;{OMoaQ?4!!pg|K!XM|&?O@w=&p+Of3BTeJQcmlOwY7j5gW&uw1MNbIDEh>uV}0~?j`v_` zk$3m>ck}m;qOTvf_o1;V_Fdub0PMyohxhhLhDM*^sj-KlnGS|ty#Y@0IzQLABV2LM zbV9sK`7w{Q`;r;@I(4EXR75?-9jfM9HAuUEEWJNZ_wqtN0y!Y?xjhc^<4uCTuMG{* z=mCV@@u|yIbk7|i@`(Y^0Gw*`!U3G(3{xkxF%3jSS)J?S_(P$y%Do?F5uh`SXt z3!eF-nw;gawl}6*z{fQ%9zgdq(F<_>%b3vE(?&EM|<6VN?{b*tpm1wP)!XNj!`E zNRuQZ_?G=1GjarhzgJ74Na<}zNq#JOUc^Lsdju+e96p3eU-&q_qyQ8T)DU1n2J;mW zRV;%%q-8N7S&njC_h z2@x#NLFRjN?@-EDCPm}Ld3G$ydv?tbAswoWbHgXDVS(x;q&ae*K(S$v@S{FbCH1TW znrTn(@RGPj3Crhd2Lwa$C3+OZyYDn-xIGq~ZeY}qu_Hp!Yq_0T;TRNvJ6kcM3Miky z$aW;zEzGF|n`S}4Z6P?(r!X3j)JZNI@pQza=)c545NRW_T`t15RIG7)=cPQa(+sgLj?b_-Dc1pW)Pq&B zd8#44cxqB~W!m%?0ZDu@h$K8JnXXn)zfXU3X!KM+nQ-((!zM42K4Gi4;y7Iav{g6$IrRw%ETs#@|f?Pk${x zQr*3A;P3U}C>RHEDto3(Pc~ECnPk4| zLd78R1a!NbHl*cW>1aXNysogU>P+*Z+f;YNat*vR$0ljSra9+UUHMIX>qK8RrMgk^ zVda(zDP7`+47HONY46ouF4b!R<2!H9>F84oUXQtqAp#?Nz;3Q#dENFF&OIku>H;|# zln3biVo#Cd4P}kKG|!yR^-M23#z8>C)a`Q$GRCkRb_h4BEEb1rgnup~;ys(Y-}@&( zWiVi(7^z$||FI_lw2}MYD#ApE!jURYFOaV{8h0(I5dtL}M6uV$q$A$8??FW=LC{;5qu+gZQ#+n=jkQh8U> z-`IKYWInj3A#+Z0A75L0Wz0D1BI<&E?l)Ppe>qQ!?1`inj#-_xXTRXS5gL?#-eur5 z9gcr>Gf5D~dcO4V?|{uW(`Lx_borFqsya*)o)oC$rDcXzZ6NXu<&3a?3E$rQCs^Mu9@3uXqZ>@3*KEdf1 z>nqk^v04(LWmY6fgAbP#_f5?beG1VxOCA7L@K0ewW6>mwMr%bmM5k`Flwn;`U>;|F z8$Q}bFU4oOeH9<2ssK_AVu8Pu|HT^k8f=rSpT5aGCk$K@k*0ju{xp)z){`>EGf9@M zql1jeyea+a2|PT~-+_jA70UxkqIu)sEL+cLP!hTw^jN6;1o2eixv};mMY!$e5Bsid ze7TS66>2|wkC<1MeVJWo2`}5y(YTARaQP1jY~r{VIhKme39DB`KQYr&wKcIlwe+Wy0$Wok6h^{++&CUYk!# zXjI-5+S(A>^1}MR=Z27pEEslpLkp8hY+fnVc*Q~e3%cg#)QVTl40YTFys>ro`l6Q6 zmX^`de^U;qfSAnw>%YpF{B7yF!w|IW5CG!go`%S4JM^ZX!rGN?E!LVIBUr|9X*|tq zIO$dL(wTFr+d~cUq8NIRNKTz8XMZGUVkFTck<)b&4{RBHy^1ABOn&SUl+rxGC$cCz zGs-YWfOxso#{EjYRp4^e^2Q*C_WD61TpWZi{(??a8~&Cxkx-%+y*19=cChqik<8IX z_Rz;3581BgQ=IqoDcXA$DG}nvbGb&^4#w3n<{;bc#A4`QiRT87w?7a8c>jRbN54{* zWR$llwD2f|I+}*(f?o4~AMmEf^`q6m{AKHXstxIqE+r_tMJ9YV0nV*#Elzj+3P^!& z^jam^!%0)~1?>o6u=yAJrh&W|x|(Z1Mn8W5dS)@}Pl0rs<>6^uXWzWnsVbtoVVrmSxo>UJWv?k$w>rgnV5WCLqUm^bwReBP zwrNX)ddwkEg`h?^$yW`aOIKw_y*nRiFXYYij!CX|(#zkh@035HI{Yen08#Ldqj_Cp z=#POawlzZUXoOWWZrb)nF}O(f@kZy{+*nK8N|rwJxO3Z6HitQ7W>ze=KG!cM#I|8t z+1+*5W~K_V_S}D^T`vE%D|!((gm=FJYBdLQ+D@$Wa-^K6@FKs-1J{t@aI}BM1np}` z#xhEYfVJe3`I3Yfeak5g{Eg=T87ngtRJlXtxA+J40rq) za*7IOjEW6;1;#^0;X={{C8; z!`AY`H_zzsDHK$?WPlp7w2}+s3(V{-*+PiaSn=b4xEQ$mGwIH>HU4= z0rlMXC3w&Ag?x)A+GLRtour)6aXvG3@lhctfoVqn=`hzL{nHnsb~mq za;P2?>|LG30tX}az_*6W5FY~TMQvY2UY#0z&lqJ1{%}8ZpuZEq`#{n z5%qDbD_*+y?MULL`sesW9FEt-DL-6rsCJQ5>0MQ;jX6(3^4 zc`JWwRtZ~87^G52sz!pww3+{yJm-X?(~qGi6^jc2NhQm~?kk^~DVfnTDvl66h% zCr=iuGlwKxw7}UBsnLVlsO~%CtKbmRn1zYjWf%8glI5jSfAb0JzX9v?tnB}Aif4+X zh1Mvt$nkGv=N0_#*>0-7@ELADSP%FYpi{@@8VN(H1E^r%uN}-i&#qQLpe$>Z8n@d4 zi=8%W?Vne7H}-D#)5pW@>G$KO{r!iZukWw7&4yMUL4t5?@k-<@Autb9``q=N8^XI-JcB7T$|avrsK3a*;Ax%W7oeYm#1lu zWv^*)ab#__wKHXGKAlY8-|yZZALhNjUOwN8ADg|owzIQwX>etEKh~^Y#wU}Di@&mX zGihmyFVB8sIEnCVa&Kkx@@{TrX4}x>POI89@Be{~036NeYRsQ}a z#Tg;j=oTSjKKM*CXF2;kvamcNf-WWEWMb9!5Cy|}e*c%c&0O)>I>F-2nN)6$O7T2` zJR=5nC>8c`ehU=~L%Lr^bfTw@bLizED-L~(=Z9+ZX?Jn!NU`S|g$~IwhZ7VggYcE> zAx$n9?Eam7yAU$L#Y6=5Ss`I}rwP*v#Kj;AMF$x6Z^k*+LUVJob(oh}Yi32@)y@{V zqamx&+pPK)rst_jb@g;c*v8w$Ue zvG3;E^}%A~C8F*tpUMUr8Hrox5Va1gEuuZ>PXrm2ZAQkoj4%7uCw>%&H_P1TuO=xgm1odgdcv08!O!Pb zbP5v{c2OjDv3nx(td)KI8q;PARV{$f zrm?z14LY_2-(C)ZIOJK$vZJ`-Pqmn0iaj&yO4}?1G@)Tga(bxNJiDpQ+y)WVnnAOL zMH;M8*(%)`ur@HowPHreDXEo3oP1j`Q#(3a+cd{dKEvN+?^@7vXeWjlVrO7s9%BP1 zNc1Bpq|$&d5skux^~Y3|)q{H2L)xWg3%UI+j<^5~%znruG_z3B)pC+ya+r~FJ9A`pwg)lT_4wf zC0~Q{zKLBP?uR^LrFoknCsXV=mq*?1?tYzcc&f~S@Qa#Z@2J3dc@uk(vIgr(a>gkt zt4q(p1jvz#f)yO%Vx)F%=Fh3Hq_|mz;=nZy124uEN`uw=AjTw0lM6iByF8jRIPPpp z?(4|}&G?N!2Wz_D9}wFxBe}&e?O>FJizM_d56Zp}sv}>+p;)6cf38*0>>BwJPaQWQ zSzOy=M?QfxngBPgBqZgBD+82A3WRxiy~jpDp-C*@iJ*+&LU>9rDYMQBuD9MQAEaehPt|^Tf$2Y(yyET_VTbV|+aM4;9g%pKB^Ctki|R zbG7b!p%EWOfXpah70JE*%BF*Wd+d3vtcp<0u^qmYw`9mM`kH>6xzE8`|Od@b%Thb$1-2%T-M$ zj!Sc@+dKRI;iaMA<(apH^)>Tvft2mv1X32}f0X337Nl)3=;1(jIJ@Vl8+iYp!dVVkJuiX+izC0Vdu@Uy|Ie2gB{cW-37zj(>l-nukPqwom?i?X$I_z zqFKB}b0O`{W?y!liTBoAT4|HUi%jRm#Cwk{-b}EUw|DAYGtSZXwG;g>OI#fT++C~P zvh&;ae{?;1<(DYCE|aC*SmRC{4@Nu@Hb#wl;}+|dcXw-5V=nJDn`3R4j|*Sy6XW{= zfbsn}`dTd_|9)c>afvkHG7W;bgbE2|>H%cKv$PV6CjSKgxIlH7LkvcOqN8tTOolZ{ z#7hyy0!;JNqwE~~P=SaZAw;J?ON~$@*m99E&g>KY8O|)^D^-4`HcBWBQYbIRDjX1< z1C!?iE-fz6wdS_urKYg;K`(OxD*THpTH(;gaOzf2k)OzY?-iDn^{DY>yOc!6D#l#J zB;&>x7zqg;BizLsF-KjL%j)FH@%#}z`gm6Lb;2tm%hbRGxf#_BOPFJflSPRSxH3d`a+iM*AIk}Ke>jw_yW zxA>JN6{ja!OCboaH$7&^LS(Nj^1zmq2yRX`lwN*{Azy&Dn^P8^CHP~85 zS}WvM)zPEAJ}-I(BSq!hTucpfa&iW_Dl0Xm3%wi#8QYN9U09w^xVE$mh4`~OvBcDx zwj1l;Z5LG!<4rg}z9>A41b8=p0T$P@k2l|DmQ_Sxua6vGt2XcpkZT*L6qiH=jmk3LzP$ z!jj@wqpLgMoDa3EWl7aU9g!lQ+k4gZtUPspFa@sfu6Qh3(66~pTfVc*#Fo|sgUw#dm{{~ z{}Ylqpx`Xje1AbH0tRpgj{x?8X`jhn^vEiMG-U=J4qeoR4`|3 zo@jtMvsgWY;Y)2k@Sh`CBiA7s)veOE}A+Qhn~iWgaC6tY}3k^!g3OM?RBu!O81o4 zDSSxz`=bkkFkZS5Lrd*1g6EjDJcI?nCw8VJ$FC30m?PY@E#h7RF}d(!pIvV)PC5vf-54>-)VIzqszjN%2y7R}>bg1QmLu9^ z6t|jxK!KE`GAJO?Xq{{mi9p0#|432M@;Qh=X4<}n0+#q}ufMj(KbCoK2s*%TRzSHg zz;o>oHlBrfon#cG)Oik=Krk8M5?$tB0Aw@;}icZ zL~(>J;+j2wll$#fR0TsdE0 zKcB;2F~NQ#z*&Wn%%hK1B38H;v`iY zDP3;!cP7b|+LV`;0DPEl+6laYXw=WXdYSB5LMm8>ywG4oS!;I??VX$d}%R5YX=CwOG^9gEo-Ew8M z15e8ks_bzt!DEIFi^37Xi&~P5h0Y)Rs7 zngAm=%6bNj>UTauX87=Hy<$~KSW^?_WaLzkD9+;@ayAa_6;%CneDo28K|zJ=7Wa1x z=5+p{W&05s$4}Hu>Pcu;W0ptmeh1h%p?UXmg#-QU>^FX@!=8wGML0r&(>VNb8pO?$mk8^Dp&nr<=*@k>+b{%z35mYub%ak^qlwd`>aFqR zlrc)=+H*oh;Ftc+gZ~rJ?7jf%|N47y{IC zP$E#`#f4vgsN9(hw7}FX<;MgN?YU2$avt&UYKavDLicftLu=<|&C-#8X87>iNnhvF zkgJn^lGHewjAfV!aAl%V52MkF$T`EJZ$_9CQJFXaNz(7Aj5g>lr9V;zCRFf3hWjEE zg?zn*F3Y7qxZj${X$uHqmz>>Af`&ufo7bFb{nDZ|u|VT%RA~1tcYooEFY~BXpoc0! z-wPMJ=IB|8(mRn2m)AGx^}vwmwWI>>EQI-)(5rqN=ju~i?~A8S(b$BU^Sy*$Me`Pl zv{O%RPWO8~Ke-s#dO`m|S*`+deuNEDGf+PpMlI5%5xf%OE~)6qyiQo2lw;z6Il$D2 zq~_Pc*+hLm-w3<#(a zWt(L~WJtn*+cT`3tV}i^;~6-+{8!%GTa#)}_fz*Aua+9I9Mcu6I-j69mmZSxV6=S~ z`e8f-VnV}(0dFF^XJ%n*4f3h+?=_~4j@nV=w5+7GdU-rg`mAiH-@=Qr#(E5^noR96?EF z*ozCEYUj#E#}BQV`7%dQ|0Ab#0|+4?_Z+RwJ0%fs!B%5b}{&p;Cgiy@S~G(2?+XO(v(^CDVp1$ z>RyF$q*#AEozf-&7dXR)-e6xDky*Q2rAO|JZO|i2zpsoIi5Vb~0m*IBFwS-%UVVM} z?R3^@*?bBlFl*pPOu*3WjhD4-qwK7LRrYvNn4<> zRp9a|$jBa`D)0{QZjOOz@Z1VQ!)+&c9b7G{&{Z`R==nxv<4j>2A9YBLf?Xnw;@DJ* zB}fb-8~!(d zMWsrmqHEx?kp+~3+(ai`7}ZxIP~w#GazICyg$}-)hWQkB(XJ9I#=1S1eQtL%Y{|37 z{iDmQap$1V?ARi{5|RLI(8xY(Ot(hBQl4iVOv`AN`DadiI}p!V%6lcUpO_0Et;X^$ zFmO9pJe%ic?GeUv0^YdOS}%;x53(e=AsaBeV?+R*Oy(|Tk0$-)E{G{dx&~!W3NhVF z!x38z&miFI?jiqO`m=*vDC-qc>rG-H{AFA6D$L({f?Or~)4v5h)M~Qp9AFbixnpAr zirK)=*VT51BTL9VM6aa(0y;LWe1XWFbulR6CB3*ie)~L_s`R#X^%P3xDhDzdZ zP$G1@RTUQO<~A4skj1nV0ZC20#n;jjNIArS77hhpst$W3;ZhL&_>R7^!7z$ z*XCmG1vH2qAl%0Tg&*;`ZEo{fs@lWK^2gS> zdfnxV$mU#Y(L+71XPuj(Nh8|+mG1RTyM%+yf+fS=GFx3P4|(8^BBBz0%#mSvd3$*h zI?5K3CX&ULx4M1<>)$HcH_;C~;BtOHKUk;Yqmo!KTk9H(>b4F&y?JJG^Ra)_1P9%< z+2@O>c4*~1T`nLkAMvw48p}?JN7&b$vyvrNA6BluQ%bZ~A0i~a+=m3mjGU~Xg+J4X zNiDkl*aA!Bu>#>4Vq(YU4|>e1xrX(`$Icr)at6>f1&yTAc7v8}CnkytifiT4bj#%w zAcsdHuW8Z|ad&V7KYdKmY`3RSE$dl)peOi@=t(S_fbWG#uPNmJ{wiX+nSv+s^Tn4) z?m5C%OQ(7)%IaH+JL1-amIE-tl}LRyj0;>=yR9*o{>Ox zEu^T?KK|<}E~q}iNl!?$G)g>wr^8&)oMz4#^W$cJW#TWCy<}IeM>1X_6b7z*!&|$1 zKZty6h+CRu9=JbL$zfh zT^}49CLhlW$iwh_cQsSGl1Lk1btuY-?~;6dq^*@zZ*e%Ee5CSH-BarvwoU`@*H3%z zrlXP}F*_YY^u4FtvDZkMGh^#@V>dq3lOoC-3FOZ(gr-=x_&ZcmBucrsqNa>%b$!NR z;ijL;l%PZqh2%uSu?R@-+iDjKZCM`;5|o0K1$rJb;s_n+MQf%}*uz27QIRACNsY4? zoKMilQ4W)_^P(cStt~7?$@?nviRjw~ZkCD?-Q!a$G80_ZNG~s-?2_?D%eWyNKHvXl z*#8*P^{;aob{59}Ol72FZKM=c(T1iksV@r?2u>#H&@Vq~h><0&@Pl^wur`@$8Q>SF z)HGGrAiqo0Y6D&=2P+yTDN$p*{cBP3G@1m!?VC?0_KrSJf+r)WS_W%PnbbxGF4yg^ z4&myMP2#2Fo+nw7e$}^)T2d!!0mkGyKnOq~Xm%Nv-o%_#rZ~l{9&uyeT$5}$nyz;7aGjn5af|^D%$FR)h zv5!o33Y@Y26oNK+h-U<0bFtshe0i#ll@0gjUIXe~T)XvFE4GX(k$w z9O4xu_z^Le7tGhm*wx1h74ZJdgo}Q1ipj?;Z|(fn`;0*+{k!$k;#h>|lOv0vD`pOt zbJ+VksxI6>FGL1y_QYTy=5DWbh@gji4x~(K`osO+w5{2#gooX|C;LE<8wy%{hUCEM zV;a%p^D|SI=#~+Gz-JVBT%-fWEqu=pA4-~C$c(`HZOmXVxYT=jdi|>($G#MGkI;Fi z_)JKGt7xO|K?R#cYR|Ayz>G|ISHi6`Q79QwH7~rrOqWf@pH+wXy^(NVhc5w_8cwEddbYgE% z#U*6oOJ z^f|pa{k{`42AJKzybr~2)J^=(In#ere<7*pgMRsD4Xq=)6QLtQ(}%TTF8fQ=A_ohm zmxm1wz^K)9)}xVw0_UI55z|(oVBRXdUp~h21pIJ+B;gFtWWAK3)Y4g zt)xg^C#~t6lp9i^ge5D4Kxl->;Ls6?*YhS(gi-g6!mn*+!A=x%6ScTw&xe(y>p@oz z#q)@Zw7y9LK}HS*&MH~-BnD%Vh@rv)`gzM46w=7km(M2eZ$Rh+0)KlK{*|79iQyk} zkhS7vZT$G)2CqHBxYw9Kf9a|s3g(rBN>@gD$7#chND@G)-R?BgUZlH_K@jm8190wB zZtExQ4a#I*wwuUd7D6SBBqX1Y^q>$-+Ej+13dzdz4D6@#rZlFfn_S-#mx~%UF-*LRKdb`?jAGuQNTvW;-mW z9#}foSK};=s`MSlV6G;2XPa2dMjZ)m<`xp6ZmonB=Q<~$>RMalSfPGXBG)^47viMe z>2M{n0lJX7Te0W*D`a7Tk&8e^!HM{x52OOF`2AmTkTxJ$?rcRzjEXl{b)N!fl1s=*Npo31EUCdz&b-L@(7`i zna^{>M7$x8n93RLL~XVEWx1XDhZLD3HfyM=wa9Unp8C&O#wrKtdJ}V(=NhFsGwh#n zaiw-dAXKpXq43CF($ZdY#N=6q7MQq5710B|50p5*@mZ9ebS`9S|zo7mt!bscB z@;m<&zT^3~f==1;h58bYce}C)FK}pOyi&LbcvH*BxKTz8tr90+939ZL`z4!ibqnddzwlGgj+m(Rcu4c6J_^wDQyYw_AF@>c3g|KZyQ+9b@Sk8U6ug zloKqZ6iv{Er*j*zXqF~_4X&Fp-}W)d$qmu5ZO8>V&{)^}fS)jDPmrMHgDONWP&m2t z70_^lT0p_p*7eohWI+D#S>>^eHB?LToHNTv4}Gh#xh|z`>8!e~%g8vMWWRQpx_|r1 zCZ&~z2t<;e-xCz2j8;*(Cgas~YT)~PmoB|hdz|l%&mVUo9~?LJQpD(1>#2sXgXKZ` zjL&R}%{%e5;fdx{;fl7{!i!y#=&QR{Rro1QtJ8T~>9;bl$WkTW?}V`?i^i58#E90i z1PBb8w^f%hS+JuBl&@SyXMz-r*X*K{rJiSpkuL9zsps~ja5EPG@mj}vZA$Oz|eR)I8K);;tE`fDYjAUOm9~-R=`X* z%(e%us`R&rQ9f}JSsjL?CY6Mkl%zg%vyyC&wTQ=FVzss6ARzV6Q&A`{5je9l=T#PG zo+AxygKF>x%+ah#Tjko9a-6X#%NiBRGZ7O-e^VDLKcSsxfwKQT-}fN^eT_t#KN6R7 zeJd8T5kwVNOE#cyTqA~RB8*>O+?GI%K zuV4H9GBM9?w)`U{9Nh8txSsz99PeGQ4v1{G&>jS&p|Z%UQA@@z>hrfM9xlvs)BS39PW#fXbf=dM%)aqUD?8xc<-aQmW^kyj0LJFv- z!>FN<+0iF6ax|#i&S~u4NWWVHyR3lbxxO;DUD>#jDPCMW1%Mc^1d$ZN-A%d=4aexh zV7vNoaP#PY;nm_|S)!h_aZ+2Wc5lv>Pb^w4TI&sTAiD2)?7M19rxmHe<)C|s1BZs< z!e3(IpkV;hrV7>6t@CN`dqwwVp3VSGj>SuJOf6nDwPVAa1T$)bw_LMXm-sc}P{J4L z|GDX8Ij^A3!tTRvfl{ToBMG2lXFZ~Vjf%xK?4sbyKm9T0chjsYT+0ZnpiVxVrzbW2 zueIfv2VI@GgbRDo5#*Y1`W$u2NDQF+z~4~0vM^r~`2)@%rHH%Ix|lfGcw+WslsVZP zEr&Rce-@R&msRVXtyI|85#)dtEkml9g?)kzYdW+H&8O#)Dm{9QD>-!R&!vVpA>^0g z@aPSkFyy+a3rCDefX`GN*oh&96%7*->%! zCug$9WG0SC84`=s*N=8$asPUxHJolk_{$UguZQXVXI`Tf!)?+3Cx3MQ2*XsAxD`cU z{ibJ%^%El_hy$HtZElr$Aui^y_p2)oi@|Yb)1mlnFA@@9Y+nPX6}iW(egaDVQ^uSH zD|gTxesJ?!r4$3)N+oi$FkwM-O6Ivy z9UH?cc}@b5kdF0^;UsW6Y_7V;ZL2Kd%+I>u$<7kNqO3m=4!$rj<-ip!xq{S=*me$D zbbbT}B61(gRPE?{;mdP!CAQVDH-?~TT-%t7JI6tQwQSaYgKdX9>;+ctDou?;)HCHZ zH?AsA5O;K_SAOzQ>Cfy)J65m{Ka9^C{yjzg%7$ymYuHw3mz%$t^M6wTqo@C8R}yiY z=bwm%G<5x^#RnX4wlo^&dM(|=&gZvi^lc!89G+BMFP40M)R;QcQ33KY5Lm$+su?#+ zQUmf(vP3MFGDKzwNWR$E*iMSE*>d%0STkcZ>4c|_YSq2nd0b_KxBGyd-J5Hg9ag$j z=}$b9bVjxDuB>sC_LXVocGjzz6#@3@E#cMiQn~ z&%#6Y*7xnE(%1=yD3MT+6KCo)HH&BLQN?iWRC!ZqQfcq%QJ6Pn#x6N%brb|`rlF-J z4cDk%JhDrl6e%CgsXlW2J2=(xo)UvRc|Z zzU>hs$uOeMAY*AkB6e5p!mJ%^&=QKj9Ye}|e5*(6 zP3GhSfOJ0k^}^)V?2b`-`=ibR+-67uBUwyBbFSK#U>GKI>iqt#*I%78(000Wo$a;F z>giIVy>JMjF(dNvIW&U9tKJJ3H!Wrr;`bP#kq1LoF}(jJHk^PS{=!g$@AUH7RvUTc zyW8vt3tvGXn;5bg(W?u(cwhQ2sou=z>8S^-2sHw@06BN}8Uws1_g`mekdoM$THNw> zKjlhrK?$vLRhpnPx}<9SAkqenXYp7-5YlpcXQ4?~@KXX(G#t6?#S(t<3FG5}O@8vH@GSQ5i zkXUhv%4#i4m>#HS(s$266+*fLu%pu|y}EdpvQ|!Aa{xz<%z|;F^4T)tHFTZVUgH~? zUHP7+?gEmOZz&zxsW^HNxQt^h9W9Riu4ZP3y#>wV>9UVMn=VQ&&$e{W&?peTU zT>GZ|iMRq+M(GF}qB{O0y!mz{0U>!Gbkgocy#wJxkIEMM_w1rpahMo_t1I{F?>-M2 z72V6{?nkHAK43y3?IU;=V?<=8Z)*yy-id*=RSv!17Rb$H^d6&4XuhSTHDEG`)10U= ze;$8vntA2ndhpx^BItybGY!LHA6k@K9kt~L2gzncMA92RZc9wc^tq&Q%b2r?YaO0o|HaA<0P2pEj)h4Lq53wYrVTx(s z6%}QuTN4R>C@S856n}zT$O2FQ?Y;U}^dTeNKeO3coj>Y$IG`J6USS+gk=Yd$4LH3M z!@iB6CR{ve8PWwJA4O4TD6)6^l8>TKmoP?G64jJDU_iBABvsnGX^6b~(?7+Z%_ z)^WC8xiOVkqT3O5<4SHBWBhj3+^ZY?8y4|pM_=Ex`|`SbWfnQ|Hz7mgeH zs0-+cx%La~^Pzc=#bmZ&f=DW%uq9BC&e6@kBEsZQohvWjpZuEWr@L-eQyx<_pEW@) zG#(MMpqC`pm9O4Fbic(n{LSJ_|3PnzqD5U+qW{pmu?I3EGHX zi($PG*?IeG_w^vl*&QH9*WO**&%?*j{o+oVNvt%%bSc?6=r$V@w8vbU^^oQg?Ay#W zBdse*&t5)NF^&4-d-O-^4NbTcnUgGuZGH0%Pev4Um6j_PafvMoQR>?{AnY|gl8PHN z1)Pw|{MD^M{YD_#2rIF5M9qYcd@5gC>+O1LjVRq4QoFN5L14Z1v3Y<3VsrR76(Ush zc+CSS^HTyHae8vX)(&cN!b`bwpM-dV1a6eX{ENK;=FFNr_bRjLzxcmq`2#`<2t%#yNb|K^7Opm+brO{M?9J#x~2aL>;_ zBic?@L*WSuboh=TK7tbDg#iu;s7s#+} zy1x(Aq=d#FTvAUcD{_8zMIBc_m8E!3|8jKxo9X@)1IEbu4=P+M?mro@Al|(yl7Ip~ zriMj~S;1&oPn* zt_3yqvVoD-&!C5H)4Qp=p=aXs{Z=JH~&-k#u|?_5|Jv9QD`uQ>j$x@%JIrJ3F{x zYnpm6HQ!@$n;xaSl8DUDIaY*SWrA%iI0kpNVl_IwhE>Gt{`oi8{X0tQpH&R4nE$R8 zeTK1HlMfOZC2PUuE+SK{Bsrlzm5rJPrUjIMeRNU~4Bd1DS* zWaMHN(6N;c+6JJ!@rxw*qP=t&@!ZwU%4aA?ep-qIwEQMJAAe;ppK_MawqEwb;nPJ` zuPPVO)zChA|NTLN7;XbqU7e_K-Qn){L|-l}+nyN^p*LM?^3QdY2Hp zP%r({Ut1&J;@VuRnY)U7e`dg?G^iH8VQqG8v3=Y7W2n+g4IB$0k^eSl4j0FT&)x;E zz(6WyumtBW2ux+iOQ`roj);Ivj~wIYuz|k-1BqmBuFsthSC+IDj;wn$lH?X|Z#yvc z`%qPt4D0sQt>f)FK^_(ixcn9=8NR$M5*+Ajrve@oh4|K^rI@_F2CJnQ5rUNf(H6-l z$R@Ql54?)NI}Sa~nCJjrw_q5>`?!G6fofKPmC;!&K`p*;f@?Ms(qRd}J^$P736TB_ zn?x>?0=x+NkiITlKZ7h|=LBpC?uXurxB_6Vch;~=bByrjIC5vX1m^eMf)gT2X`3Xu;7OtGI$N{)KS(=hU7hOZ@B6d3Fzwww!lhAD1Q%R6401RFF)0CgY^t z;eu7v$Ft->?U&g(M@i7NbRGLjhc#)VP*g-CR*~n5`s=V151zM-l(EChhX}RJ)q&&T z&RrTPgG~_W%{6J!+~DlGsJEBr)r#|HxJIReu{t!WG}a|6KEv}%&pYV}W~#?(JF^pw5w$|Nus zVKCDZ%5eNO8oxlO0*YP#@>eteD?Ra_73Tj02EFD3cyOI>|5ZLC?dX` zyHIdr;t&rM8B7uU?3#skKjF_r-*)d{Ra3*Y$OkbbwJ{3+=4O>JJUXRK;K*hwXb&ne zUgLC{ly6H!iMhKq7!t#*V?$eA{8ney4GWv>kjU%X_Zh}U3*&3$>1mlvzVj=63;6gu z-kau+;vLi#Zp!sttqf0>K<)HzfaE&qcmUuERg~!)8F?5{vJSO)xvjlG9;z{4A33#; zsxtpfiMRK~*ooUKA=hrSr7(jC?2p~I4|T;hp4evmJb?%|NeYu|Rai4zaxJDj=q;6_ zitq}@PayOH8~4AN?tepmFw^}5=^7a7>gnkk8Xi1CKR?|-&H$dEqZ)u9R*pXJll9bI z9C*%Q(Sva7B6tr{yha$m;7nrOPX_O@gT<44eRrGjLf(g933$PM#GLSYU35Zx6Julj zyNm1u%w^22&9y^)eQUFPePbQG_>JU^-9$qDMCywCatjMvqx@oheGB~ztj*<(?e(+# zZ1lxN%&qkyV&e1RGO{yL)fGx}^y1|e6m$!#b+omsl2bG)l64ZSi%aw6vee>o;S$s{ z)RmIb@^+H4Rr7X|Q_{cVF#i_?YIHE>FdVh#DGL|sVF*4K@ zY`@L+J~Q^YA3w{$>3h_LzYb4cALiAg0%+Bh*0iXKz1wims|y`7W4to?~>MxQi_-&lv2+ph1hJa}aRxF2@E$@Zr&NGG<( z2fAc`e;%~2KM&q*>VQ0hRWWSlZdPtru3N2FVm_yDcMnyy2j)8o91FGn*lbUh(dKd( zpP=4;Bw_wUq5QfmdvI4#kQO&{<`x}4xMH{8PK^%R`h8V@+}`hZeTwDWMSJq8b;Eh- z{9v=X9eL+581B7BtNTXHnyD2P?wWSyjWZ?ArOC~;!PyG1zs?x%2N~$t#tj1kg2kJJ z{@YFZS7|8&(?2^v{-E5I7HH zt4GC6WhJJ)E~_v)(5R0gQf-5e~Izw{zoxB(?5U5z$DLKNQ*ebCVI|6hQ#Z3qX0`|Dv9>7J&jni zBzr-5xqjhEDea_0tzW;M0$K0B{aM5gdrm_&GG6D`Lv|NOMv=B`)IZmzjoV?y&8=16 zX8f9x$UQyDxSo65TJLk}dA9U!XZ$?D-p#&!{rc|ZAe8beB2-LGdXC{T8f1VrHs^Ru zf00>3>2IqFJ@q>v2`^F|5cPySRBXKZZ? z*aSQT>iFsu6ewR|vi;pdg@qJHCSrnOs&U=WpMqZZfxzn7c)IuwvQektF~j)0>HVcX z;lvFBon*O%CmHNPAOkk z^Mv%Jt<~%>&@c-0zT3ffB)TPBZ6+yH=O+=73|Mg*R+?ElV_#5hw0G9^8JFvSZaqaE zQ=d)P+B3yVRn&hrT6zM+I+{+HBlS-sxwdPX-!?xS>ppVaV$AQEJ;!p`O%9+COrXTN{jc6F?(^R*SkxCQ9r>|<_ctiXAIcwq!Gb0zF;~$$Y zPl`CyKDJ?`DaqS$7z8@CLVMl`w5hGopZ?=~`Lc|C@`e|&05k9^0WH+Qsa?lJj()d7 zs{ID|aiOBs6vOSoc)?lcr*?%C!#D)P4;f?=)I)Vh(>fN7;&QSA`z*_#^Ia0Oxt`23 zR^tZ7$k&`QG5DdcKMPOq)0|uMA~XOyz*Nt%s;=ygBi>TKA$J+`vPEF?Z#3$?{q}mZ z*UZO($ePt8DNd1HDKxmm`Xxqd2T;IzD6Fh|-;mogGD(O?UZcCZ^ojXK)&pY>%YdBI2aOYI z*Dc{1>uy5t8EY9c?fXUwyF64$5p&D#m~Y6i!gJlmU#jc=%%p1i0PMOA3N*w1*ad zDi@9|wFTgDB4prToH@(YsGPlZ|?ZFzEDw)npst|MGsb$UYO2A*| zsBgrp6ws?!emI=R44+@9CfB#N@?rb=d+UupBg)vfkSX=0gBV&#mCnuNv$q+^N%yPk z;~~nka~-TiR+Oh@C=uGwnK2j!r`)C(i#ca(RA~*M+*OJ<$Uo@Rj$t;}*t)8`J(3d$ zo{S0Z5{Z)uH!X}KE88|tJzAKza2A}E#V^=>M)wrlq)sp`Wz$Z(K4^HDe8_s>1P z(TL?>Nh~g&uFS3QUa!_3^9z|?mQQdyd)gKuhX7_1kQv3_&^=lGXrZ;xBFZCB<)6Ae z)ulvmJBZ*XPv0z18R0Pie6(jTo!94yLhjrT*NY7hpZ!@zd5&Ce^k`2Il<58xJ2D_GSa8{m5GQ1tB)b2Hv2zN}EZVkkY<7~4 zZQJhHwr%H+&5mu`wr$(CZQXu6x9Zfb`???YdfK(;_|_a_%={YEvrR?P12F{I^X$xx zIY;rkMDD*qZVZO$-zCl&}qO&1F%yLSW{RjlCfv$~~&2mdC=Ibp&x%#2xW# z$|5YWIldX?hS9p8`d7?8`O(}0XoNb941R|EGvV_X|26A2!_X5%K>wu|%0+2wFWvfc z0UZ_7bl?0E`1RG}4-_ZdJ=JW)9{57Y)ui6pRw}?vumAHuBCd)JIiMvR?_i#;AJLOBPefd|J&WMxuBBE>cz}ci_2F_kZk`&Xt*7kI9#7iJn3y3XQy1>SqPkQE| z{WC6?kPat5`W{H4Yw$0>O#*#Di@Xsb;~!anz5BiU>`K)wskDj4qCfdz_VuvApVebO zN)GIiYMUa1EhDyG+FDi>4DJT^*3H3c;cR;KfMq3 z;h$UiPr}yM*kzpO%QY5m81*=Y1|Wi#5%yL=F56DavFyEEp&R#rJr^}ET7id=ZDpgNnY z7M;@GbDnKeL(0^5wY?5*Fme((zY&^N8~j19BkI|=KJOvS?OEF#JmS?&V)?)d^EOH3 z%$)#$riOLfnl-0ZS*j-p;Jj#Gzc*0b%i_K9CqSf(A0ZO>1Wu@<{pXrkPWRIx{`PB?Z^*&VxWl{Nj>i`w|2wSS z&%2&|=GzDk)(T#S`_=G|jr30rj^?*htIs#1`7ZKH4rgP2pTkof`OatOr}rBhj-1nG ziSEyPNwwZb*@d3Q!E6ivaCA=R^XCG(p3yhYh_86ag_K?E^Wjv+P3wHf0dh3)jqiID zdk&xH@+aGf?<2y<9mwOG$Rn`qq4DWYgnj7JM)#=2CU7f=1diw>iPW8 zQ=oPV_0|{J3%cu1K!u|mu9jvra2!yVKz-&Pq-1<2GqUyW82}ArBJ2)&Bc3ZJ|Uqo5SbwG;RQ! zSVSuC;Iz3MClX;>nQXXiBOIpVe2`;38NoK8)#1arp>d11Lxa!9*6B;WS-U$mYJ6kM zCa-xq*^0fn`bADVNUT@Ko}Op__3iX^O)8`4sjA{m!o02af`YS$fn#N3;}}tQb#vRi ze{S|}@72xT&3NXl;A=s_B7?i332?v`YBjq(wJmxV?RI+<0W>yb{t;)Y9L;9e-_!#9 zb_A=2*q^<;BUChSJ2;OU;R%*}fhgiCZ+A0)>~eNqfF9Gkgrm0+{WG((w?6kU_Pum9 z|DUt3)-|zw<1WuNEMHjNz`TTAVTW_6vYE}Cyri@cMV3Y)XFi?%>J#@L$Ks71O+PkH3r|Md2wy+QUT-zz z4#yN1R^1cejmk6j+@l5pD^!P`GD2Jvy8)e({bTOap^e52nQAxW>QgdauQUHFHGX@G z2Xlmpy_1WO9*b?W3sJ5y2>C87LogS|@V^zUVU!FXZn~}JL2wQDX zh%>a{Ri!A#*y+UJ0rQ<@uXQGQKkl=-J-e{CH`5ARt!;p`Kxk+E0UCU_xmHHWfAxSSfkT39F3R+jH1=0G?yoY9(t`#Z)4;7?=g&8rCuaGguDOn z)2ZeeL@sJCxOP^I{>wb6%S^CThSqx2sVErKl}k%C@ao$9Q^Z(05C--4&mgwS8+}a)n>hSddzC zFxNrT)crHc+SQ7lH3D5*^VdFcQB^z|t%x<+j#nzJT8qf4``tTh@gI_5&slpoEXj-* zpqGA7_G;TFP6S(&^FVf+p1ih;xZKxSa5q*xqh0GBw_@if!?SZ0b8rPpGpP+CYpEDr zqsgJfgEX*g=G;63Cz}hN%?X{L6w?;y(=)M}t;q4*e@!y`Ltr13F(8l8+&yhmCN0hR zRW@Kcl{URYx3BNb%KYPOw?EFz?Jg*PN4M45U6{LFLEEv7LV0OB@RI2JNxf)?NeK`d z=ZLKV-mw3^d>HWz^@f(rs`>rpW3x8u+~2|PPmnbM_jDRXQHs*%R=s0z&|+(IB5v}I zgjIF0d*81;-CxEJ&uEGp7GXa*mSpG?cS?C?Cu}V%ao!vt{b)OY-0ACuFh z1YsS>I|JL)uKY8ksnjn%k!Bc)Hy08na@V$|E%+U)opGC_Pb_ZGEL7iLB|yG-Ij z%4E4CKwh!s^UrT&tC1MZFQn?c$>xy5N#?}+Y<{60+`E1@PIJhEsyKgDosBa>2l{j$ zv3Wud&HZi68|^d1z#4g#M3bxi^LN^Po;2>87;ac*_K%GMu(st_H})JIeC5MNBXM=#FhxX!*6q_stbOD9*Ea(`Tc8V z)KlxJwe4SbRjo-BuY){-Z3Sf7Pro&a2^<6TqxT-7Cl|R3c?c2;JEH=QtqkL4Lbs$_ z`C3m)OpBON-1SyR$y5I^?CdzhQ|M&8HSucr6O&dw9N=yPBZhzJlCy%I;k=vKXOlal zX#QZ=3|Dy9#y`(1Gp+nrhi3JNq%AB?_DGFR#FIRZbzyG`*9edH?E-N{kZNlZiE)_6 z9MCFIUUOT#PAAm%Pgcjyl#aAA8los(GOSinyvaaWRXpfk@3W`j*>` z;4L1KtPAces6$)F54vmGg@Cd7S96f@V8`Y+y#buQ$Iob_}^U{~iCvvcWjah!Ie2=RoeD z7M#RPm$9HkrPyT=mhs+~qxS|J0BCp%JWC_{JO9E29{vp zg;fwrgaf1ALM^n=>Mb^GD^^E@hBt;#ySwIh3T;FC>swF_n*y60-Hzq@3!oFj4b1qx zn36F?KLwKO`(^^vgwjLd=ZfX!Si-_0JF9>``D zD1M>wvi`Xve0PnssPvHR)2mpoFJ5r z#EGTu?i;n%&z+lq;xs6cg3=RLYw zx7Uy%{nrD%y6>AF5FW%d6{6b(XyZ8K*UJnF6+zr>s$_niVO(k@EX2I9{|HkOgR01! zDzGfcEHzc(DXx~1V z?!vO4>Bl<*b=g`q0pG@spZ+hD7nSL~c^wfp8F&;BVD^jOo?g_~+Tvc%;{5Km1xwkU zOcit)-&QjkefSqt-iHi*w?Vy=}vsK_6DZ`0wg-uLKn=1 zOm(H~Ui2gnS8O~R?n93`+72SR@{tb41=ZC)!;dF8dc)<{#duHfip+cgDBXhxmR+iS1Re4X|?A@@N+BFD5WYqO{eh=6@Zv3c$QW)f>T)GC?!2?{^O- zf{@vXF_wt&rG>iSPxqXR3e6V5uN9B-fbewN5*b(j9ImG?-YUC;xtU5Vk(>m{4jiOk z;@p=tHV-4yf!F>ZUSDLwy|)gswvpN$z6exaUfqBk()) zno~mzan%aEl*;^3tH-M?GrSesgqCAbK3Bg=$EZ7;(Qe_aRB zfmrS)vPgjGl}Mb&f2FIn-907AS%H63JcMFH7CGeY{`niGG*ZGCh44{KLRFp=23Xv2 z@*VO9FV%wZN#0D&;g<0Aqr*MDmG#YaPiB>x_bgd?JMP58nb2GI=Al=}9tn8tv^*X8 zqenaK{r>t_UYEWjN7yiR7^Rw`LYS3>7vQ!1JL5`N?xJ_+2k5iV9Rc;)txh?6f;|iUsM{c#YpEle` zqCb_E3bL1;#WkKoS^V7h(bVA!>GDW@`;9#PA>D@Op_^5KD7{(j6Z?9^U7X+F4*snO z>7iPtM;*rWtM(N2&jO3~i}g7s!33m=+`}izbi5uu^sAASUL6ZfxiVsNQ*VA^_LKn( zI@m=X1x$Q3(}#J0?KgKV=I+y%sf}j#wGqkh$Zf7-pwwVCX4pcr(ZBS7-nY}nPJ+bz zQV`n0I;el)I}`PXqdYPNnHTb%h=nGA2qoKkB0@J^K2JUodV2Q1QAbU`nnxeV7(F8qzpf6-WK#vm z*(!nezqX57fK7dL0h^%p@q1$OR8g~1w9-j_IY~h$JeE}X`gRbi`JhwT-8zTQ4v?wU zX{-FrJ?e>p%Z{cV?f@0t#*?ceQjMdxaP74st9Th}4v6(SlqYrWWI@Wf!BuCHbP*ya zxT>qcPPnRp>^M)tCiSxWGKHanaUOuVs7`J&h)Y3OBmzu6K`Pj*EWZEJ0crEfnX_*7 z63FGGe@TTE8$O2qFX|ArxiGGyUxDEP$Of7bKSi2V8Wj#it7&$DQQr_8uV$^Vn`AFo z*P5>LUB)`UhSG@7AmzXibvrqfcv87vdqJ5?rd6h^s{VQAv$c6V|2a>pIa_K8W=3Ds zLqDutjL7>0V^51b9cHmgw-0OWObsDpN!Sr@*G|ulyIpTZjHmNZsZ1&<1tu_$6?oAK z%1!(TWDCoi1092!X^o>j@)3<^j^osl^OWq;vN? zV#)L)Ny0fVMi9Xh^`&5?0n)5l&vE>b znq`TWx zFp?0ko4&q$ya4Djuk|BG&q?E;iy1E5-$DtEkxhJDdrrU*7`Gk|E2A2mMqVl$uTBY7c1_F-T^hS;stvoC zn7S2LT1lec$WG7rL1Q>(0KE~T9!rky=^5AV$PLgkkc@(V76uEFQazdNDM&0vW=tku zlKnhjO|&RjvZPt>>)2Hflzyv%_03qmN%?K#&*@a9K7-qT3a`V-Kh3bz@xeP*X(|;Q zD3t0qaq(AY{E{=#k>bCJG%WY@s?Nm{&yCkq4F(H=xZQUZWKWv}HbQP-H!T`V&Bl|O z-AqW;&0RWeJImtRMrmG^f#|%P+7Gc%R1&t}n*S@Z?o9#jAB$5AB_B|@6?ouf>o|z3 zM5H|j*os@c0GCTBvMxQ9B`b&@YPNIlwqAWxOoNI?uNwRm_@|e#kyPkwN9)*zLc>ci zAoS3fiHg|lcC6kFqjyYdJq#4`w_OW!$x$l2%^xqrx#4D^5j+*1Q#Cg@cW23sw-Fyb{t*~oBAKLabFo+)e0F>b zdpGYJG%cQ2@nt!x3du#DY3~yw0<9=23#YSS)$riJ9vymQh`Qf|LkGxA0cfpgWI*Ki zj_U4h-$^!EXEM)u-wKW4h1ZHI3Nb1}#gb4-hx4+0q`*hxh{7wAH-;jT!XP zt*Wbvrj6zt*$tX)d`AXMwO}FKh&kR`atEu?d(L@#I`UPNJHnL#0|}_V^y$Vq^eAtF zTi)AJM)W8FH_`G^&BinvSb72k@PDw`iTM_gaQxVm9CIk%y^ew^_K>sU5q-4KS*2X1 z2ocbyO+iEyy;V}yQOK5^1rIBzrI^XsOn)=Td|H9OUgP`UFo-LKW}HDdsiLV+sfHs( z2SQTr60lYs>jqrClJBld)ExhM@3QZjGwa8-dN`gEi$kmHoHX!rP;`}3K}#TVTEJN% z&CR(usLg!~cR0V@dpMzi!OaHa?W~1En3SK2iv71@tW5cL>oQFu+)A;V$fzh38{yVq)X-4d0un zaH`8N-&=8Lz)RjHD~;{(!o6F;4^b2NXJ7On#JVmYjA)fAT&$D4gY z$8SavwB?}x0)^qk@X`tbw9%o&W%AGM{++ppOMia-?J(epD1WJrr79(&V?#tebyEIE z09S?hl)9Y`hKn_zd9Uj1T0#JpH|z}SdoZXj4aVV#qcl06I>AblajeK2^7Ii9+r)a@ z7Ntbrk*=wuRiH#%6{lGxmyb)!XLVDoFuyQOAT{Yc6sz9^xjE`=8oagx_V~MAfNy*i z5^^ZM2DC#1XfBfTmtjkuz^fFZ|2Slo<0wWG?Hq+t-$Le^@>p9Ew8M9$36x1ndTgsv(t>vG<#@1i7poWx*_j_RzR8u|Icg`?TCJvPl^DsQvRuWq zd1D2Zl1T%qXYWQqjN~BPCs89G_J<}+vu&x499W#+23>O_?F6G)~%6;qFjUZ4KAWQj&cvhq({HTbmIIC)|WRcQTS~2rq+&@uu4m*EV#d+X_w~moM~y0dPo}4AcUn zGSjEmfd}oL`9&Q$LCn#iSCNEn0^)&-6N`y3*WBg6de`girx)$qH66_D7w*N{FnSY{ z_MU@_g`-6dV`WGW1QT;HKsb;D^AIw1Y`$JzWO_=82MUZidVJlTu&Bd9aPfl)MsGnn zZ*_ydvW@(e17NwUdf{zxbFm6fd@LWS>1A$SR43zT5=m^ zE+AD_nN=u>jKwUl4IHUKuP#UdGDC^PM#w%Nb?T}9$$Ywhd%TbmRY$_3Al^`=tIpei zEdgi-=YY;Z&e5#nX=#F8GW08uv~GizP>^EEN&Bo17F}|otS#{-1?$aPm2T{1VQFAO zR=3m6)uY#S{YyU&_o}&(cg3jJ*?VjDlsrqwbUJk>yY{%YKE>npbLGnAgP@z$}t$(X~5Nu8y@8w&C-QRKhS%M%fuTxD4$9bHlVy-Scg zV)_fi6d{y0;ACYQw8gQ?#esILJN`-byk$W1YDR)Y&Hy+u$BZK%jmVBpEcI* zt-09w9^olvbYHir4wP1RYf+V9u+b!2^$QN&k6N2Mpmr{;Wz}{kj$TTPqKS%O=-dgo zlEi%LD6o&sFT$W53nfpoo+&ZQ*D)gEhoNabhHhqTa5p&k!eGS66^aa5e^hXq=A0oK zfcC=N7ltrNV@1wNGKz`V;q10=5rQeQ>gNN3=gEiH*<@u_7;H+kyZH)W%OP%OJA6Sq zpGJ1uMqA>tj1T-H4GjAT3a_3lyL}RuX;duKY|^V=7gMbsP;Agj_{E+K+dA`L+PN7u z(s(qH^BZVQgI-r5zKk;M^z^fJ#g$o^;$tVJ`QnVVjJ zIdMe#o{WiOaZcJY!+d1foaP2t!Ab+`N<%xe8fU2e-k45Es{JjKNQjfZz%~nBi zY*iQfd{~=N(H^SNub>SP;JeDxAzqh;&F4tJ%eQ}cU-tk{pQumDI&!Yy;-^u`O2qTp z?vQWHHpEu>^anK_fH}`FV{Y%Pc_p}SMz`7@ZH01nRTafkfje_f1M-EX;8@c}2(tGLmK)wrt@%V_6NXtwyR~K+ zE|0&MhS6?XPrJIjOZa#a3p^CtHd|%PC z3~`s{13NMWz8ra!3jalqXaIE8dlw2@1`FsF&)6CRDX9uY$)_355JJe{ezg(`4l(;= z41;1T0!4sO&u4b-C`Fg(ObZ+);B{!zx}qw!Zuon#FOgJSxuL=E-BFVivHcvX=Bx6e z>`)eni)vZSn&uADVM`R{&4qebBk-Uo4b=I7<4S_=>W)y6-Cbo8 zbU_*1T?K0nGaZc;G@1=q2e3p#49UB;L;(5KSa@6#e9XL2`T<0HMjBJylAjw7(9Ac( zYXQR1Q@HQati+k2=-a3mEYim&vb{;wB?_7&rmtb>P>*BhugRH9nL{FvqUGx- z0GV%gIM_UsbKz)GqQjLE;W0q~;y)h(_yCLhz@WPv@K4x@iQ;^wg$fvC3^}c?&uO@! z)X{_cRf-7S1;5oWIRD_~QjRx$a+sfI?8eFzt%4}raMKAcnx95C-8*w=#9WFtcTKDY}!1f zznEXC30l&mpCBZg0@;d9mU80K015Nin1(cLbNFX`xqivXf>*=`_G}dRt;O#))@!(f zyr(75hAGNz2GcYYC+p``Iy}R$c;mm-%socEg}gXuOf%LT-oM!1*GV_2x$4TStWBGm zsopJJ@& zgV&K8f$dk^3>($Z&?EV=v-C|lk*8Jb=%qf9H5sm>$Yn3a5|~%ulxWmny0ca_d%Ag$ zYc;bY&SFGAP?KOVY#~|t9lVc{7;`A_Qki9TOEfT5S00eyKoJ+>YSRwWeAuMBaJZDU$C;5$^&;lSq9cqu45N9}4Yr9?=D zt{x^C#YT>WMFFdWg=@#Tj(gqm{+^6508N~(h9^o;Y50I+=j2-qZiL2u%Y4ORIx6}e zt&RkQW%dm&r>%v<(oLELbNz-Pm>1|T<-=@G%dsPP<~9|W^Qxl)Ua)X(Pz@oY%HVDW z2+t21=2dHX=(*SizY@GMQ~v4Ul!~C5hy+fTcDBao!R4k`TuLyxl7HeMgDFmP%4C~NRb?D#2PQat z6_qBU#6^5!IhL^UhM7GNC5^EEHZLZUdp)W8Q0 zA7;wOhMV?3oYHEdTG3c)!R%&WU|PKX@oj0xXWd;YH)xRYpO$L7cIDWVZh8e<8-j z7D;Qb>cfv}alr_A_lYU#+5L}56ZdWDp@#z{s5*q`(!NS9BvP%ctmuv)yZ0NL>}~wf zS4IikqcYB2YvR^y#0+6`&MnwUoVK)@9eTFqteJ>AN{N}~8#)7qd((s!r$H6mbuby$ z12Z@ZIy_M#gAX8>b;f9cX&DLr?vc+j_N}FaO1v>RkTTe(NtOU>$O?z;m8MldlRUKzN2E5oScD0-=zJn@l zn7`qR04%(?QOOY^-1V+#@k5&Ilt{2HD;DGc%C0?z`G~JI3<&ojdZmQod6xy&!aL;y zjP+7gWkSolq424cvQHPw83h^bqdKkWG_-qc+*@5UrsfGFU8e>Usaq;$rz9uh)>g0b z!HGrnB+KY*tuiz*ahw|r2iqfTq#HWN&{TK{z!K@^GBp~Hm;ikRXQpQoRbHOIL>b~5 zU2i__C>O8E(5~g>?cqSL4jS#YO!M!T4Oq*b2*!2=f63%uyO(- z#xit+eyf$f%MR;ZwCPR`zJE%m`a;bA1ks9}pHWxyV{1~GGHIT{{UnIG;J zXt&;@mn)-f#Ui-sJ(tU|c129t3_V|*Ty%0!WhA|F>0~FLI?u8KrPouR&L?R_S^~I- zK{!5KMkyQ2Bnps_?N+dFF5ABL^y=c|!N0x(#Ts~Asl5J5YfY8y2hM_?EZxVh5;GG( zU1Ja#mOM|ob7%rvi0Y-L>q4SYP1&3Z>l8pxu2@F`D@v$y_?C%pjDl0-Kl7tDdqYzF z+oCoyM&iq>`?q_xJodDHvxj>tFXuOxRO5A4%KhJ($>djUK=4eI_^wpKq?Mi-!2{rT zOy$U5TKt9}G}sbTxJ%&>^D)z}uM~QGM&2=|qW-YVd`qU=S_r-^eh0nNCAh)$fXRRiZ~4XPiQP8VD|yF$vE`Ky*0(TgM&9nxR+um+L$U&;hz2kNVSM)_cZoaYEc=oE z$9Iyebf%^3o0+@Q!LsYNK(=3+?cp)XDpbax6`ZVz4s#zZ{n37slXpG;WyY3am1-oK4jFq7%L_` z#zf?Qnxgm8SQ=jm=slIUV`su$PS?=!+GXHC1N+!1DGBTSHzNQx7oLrpF#;MBDl|`$tmZ6&()Fbe!B$s1E&6M? z8 z2y9r`ePN2V_QY&yK`-11V=#}4j?EnVUnTaKwfsstzLu4Qpkh`*EF6O7k%^K?qDS4) z{j-%TL0cgb%;*q;9b$#u+O?6J>#SQ{dGm|i2g5KEl^7pz&dZ3tc!x`$90hXi_Xejn z0FU)p{~F77y7gl78SUZG&%+!^lN%dBNq_yT6-8w=L(IAT%!?Ebe!M6!y~?Mf~gux13ceDbPPvLq_R&aFkyHQcm zWn(DwMYKtfdCEJeKNi%qipe;CL%%>;6KSpSbv(HV41=YD=<~opP{+-Zzc7A^cc~U$zs@#x)2TupUvJm9_K|@Z1jpXL?+ao_d z#sg=+Jn|L0pT6*t3xi8S?PGWM)odP8`4{i3BssHI`KLN%;aioa!I38v5Ts?u)=k4@ zPD$}Q#j?9c7?->!ac6=!u8mzR=+8cEvTKFlzP|{Mg^dRlb!XTiWq_)tW2&nkSPhFgG zM6|{us+`8{if3g)!Z+rF?{?O_GDUsb#gdAp!J}CnZX+UsWAH_^@2lO%qU5*5YR67e z_VvG=;gsII6-he$-{QgJu%cB=wwM~!|JDK8NeF1f

*w2(lC+3#u+^?vDD8Y7O?C zxet$^@nG|-In+}XuLPLEAPYL2R% z><(=KX4$EDp-^v^xuxu-ayn* zFp2tLrJ>NYu??$T{wd}Vl?FM1JLIHbKbCHIL?f;K^AbUJLzQplmU0Wci(iHQFuu4|>H0A;R{C?tpk}pPwWT9}kaIh%k~XYF0IB zCM=EpxZ6V8YwU*RH{oGndtRCHWPNJXKE_?+2~*@83oeqh5vag;H4mNu(^q61(~tVm zKBPz+f6j-pN+l8gT~;AKQe2=dKF4A!IZw^jN0IPZs|~A?$bJw^*lt4^=s%|MA#V=m zbIs&luS&&o5mBfR+D)6XJopfO!R5%EqLZertTb;wK#JNVUuv{s=4NrV9jzVYK@xNN zw)a2J{uR$V0P67Tx`*%qU2xF4mgn%9{#ps(pCd{Z-p8)biguGHV0(IPz^2Ot{W+k7 z`$ox3>)D>E;v+jj)%&aegztqAugn0q(L%FAKYgh2Z<&b#Lz}IFlOvMJ5sv@3#MHMd z;qeEAn)G?#u&F5-d6TS7H5*sC#$rKy;=JMuF6^1w_~qybfgcu!aE+$Kf@ru+U3%F9 z6#|+xyUdSGw_W|O@BRa%nPq^h(ekaXVbi|D(Va>qG@oA_fF+Epm>-LWRO=o3F9_4Z zpo03_6{f1E7a5%+I_Jstjv(CkQ!ATk;)Q*QhKam$u5A@AuZPDDG{LL71R^-;r0GaN zzL5sD5q3v6F9VN^ql+1zbWJp%l)_Fxiav56z}VQFLI`nFP!}ArMLyf^p+Mb$HL{&d zZ#lERyhCPj@{|<_?I=Jw0>k3uDJIpAbmCT2BW{X9KkVP`VVL)zpVmpVBRQd_S1xyb zvZ^&V5^wB-v-{bj@`-a*GM~@6^80O_(b?wr(|q?+6g;s_rzYkSubXF*2UTrPN5+kw z23x5oPIbpSA*v!7=!eYD3J@})n(`Y2gG^~hRw8b81375K%;H%mXO>_vls0?PHGP>Q zY&GY!kHWeNshhym<3al%zN>U^)O9xa$cDeYpu)XuIh?=ITJIx`a7wZy93|Yt9sh00 zuM^guoe#P{T-5?boEu-gW-YB5TW8Eq1qKsZj9SX-d*?$3BNuCb@_Yyq%5Jo@t((r- zr}emhW`&;2oei8#j*Pz!E5ui~sph`jyn5=%FzvU;1W7>a0}ZPT=xy{D-xb!fp-f+J z=KIt|J+G_W2m3VyU;a)S1vM!p|1vCqb?Ypn--xd&BvQpL;4de((az{J!HJUDZ~(0W zudiHRqFRq-As&JOT3AOB><_qN&FCPffFEeGDxTM`OuCfVdUDTA5U!wUv{@R< zR;;IkaWeN>Z)C-9&rI-2!zpe~zf*eP6sk7{PHVB=e)MuBNg80czdJ4D^MOrP9@oqj zu5}E_sd3}Tj51PDDqpXjYPcaXFqmc{QTp)aJMnm9RXc%?@gA;F2-2&ZxYC8Ep5Qen zu))@@z-Du-uZ+OP=K2NZ9em(C@sRHEpu#h-w|>sSyY#Uwt60d?D_)T@X8AI=gz1>n zg&~8e+vV{TaMji~kWJJxcI#6tKiCG+dRsy&&3 z2e=a|Qzp#Pg@WV#q!f~eivW>wZAEze?gI0ilr1n*s#grxRoclR^dduMUB zTRM7n^LMj4uVAz2#jk0@=+Jw389~h6WGmyc`hH`ix5?|&qE+T7S_7Wrmiv#+-^|nL zCrgoP?<&VH)xwH_B#f7m{A;$z%n_sjL6?a{vmV}S{rdRU4%I|Z_oHsZzb7e7PSx`l z?c4e~bMOZr{-s^)xNY;dW(aaKXRNi*13@~`V0boBTy0acX8bI>j} zzuVYuu9Q^OT^fZLtU>x^4gmc?)1ja<()2}_gAEPuI6kb`NccBkHf@)=B&U3h-8t}I z9rl&<^KBPcx(+WU{B1fRCKJ4vO$=eEPL`1NwPO)nFXJ{Wf-hMM>Vu&xip{r@D)!Pn zR;mx8PyN=a>}4L2c_UDC5`%kd3b!c)XqYC5dMA3{dx(zdN(OVFQ`VoFxUaFY3X&G< zd8MtGx^Wswxa+EFZ>tJZ&Te@_EFJ3FW-aM7Y_`L*9n-XIPMz~rLG!6)@XvEO?hD)e zj7!=yD&Bo9G%dUwDulqChxEX+#LjW-Om|bP$h9FJ?L#{C8+twRH84fSzKNEQQ0#U< zE&s_@bBh~UXSMbYKLOxHu0X@EE7&6KM8DN~o}o zq5pW(fWC3a9eAyqvuB(c{=k|`Xl~&jb{8(|<3Y6g(oo=}yVY7@1P~e#S1pPuYf+*S zA7+A1P=-^<@Mo48$`#PaISsy}S*ON_i#$$*n}yz}9$_-e^Xe`nNes|}J`pb8<1bg= zhSU8mH@v0?!yc??Bj(ksAVV#4o6 zw!@pc&&EUN%UbxRod*Vij=UmQUUAvct;otqRj1d+H2O^vAEp^%vy}|@CPCD|vMCob@s`t49?Mi3kv)BQ+a@c@sPJnybCYE2=0$c)XAfi3q$* zLtXV!++fZvtKBcfm+DP1Y0kyEC59S4D;PU`A&MLqs<4n%(}EDWk1_Nl^f@JS&5 zcp;y*iS6Z`x+mIG?x>AZ>C71Zn8=eCFs(QcQ35L8ZBtEqinkq!=wPCxxHkBoxj&2f zTIHs|w>-<8>{e&B;MCE@QCg>kf+otccDQ}0y|@?`ubC4Q9Jiva+*hgXLe1BRaN6ASAvV$idQNT9Mnj z`=Un;S;X|M5M1zvWf9#@=9nk>=MbX3gAgx2%>2+(7uSw)>ofTjXLzc|ack9?8N7z? zVVRvdRYR3|!x^C+UfQXHYY%+2UDc9gfR=EO^<|F%5A{!c6jkV90RAxuN;J)R!BP3R z5>l;!f~O|6v$M78K6hOdG>r$o1CK}d`7llVpTdF4TCh+-N)B6c*<$s#2M@YLqarZq zeoTv+CZ#n;)=Z6Pru|;3P*V)j1%lOyf+P}67iGn=Y@8YM%!oHFQ_{>|$ez_AY6^M# zQc9yglk1IDv-<1r#rBka0i(w1gKWJ_Ii_U#g`~Z&2+WcGC~PmOn0zHJRxZz_DYDUI zKudL;$z5(1Azl>(lFe3pefmNNHIB`HO(RdLs;s}WcEpdih&UoIknocj5S38}VnUUp@ol*3?;|v38h2gGjG82lO z?~i#b)zK>o?iB+koG?G%$~zdyAV{gE(T-ET^9IuA$9$T#Mr502km(iekF&v*!@%Z+dz)YMK+In+#wK9xh-jS_DP#Bu(?ZbfIwUm1fIVBB`J5kq;_;$kq_GC1ZEa* zewX_K=mRz$zRYI&E{@ibwwm)0^Nxbyva-`@gz{->Y;8(_`5EJxrPTGg`V zirG|ZjuV8r(Uq0C*^!a%T=zbJ_KIJIMjP*!;U20ojDg>QIr%UrTzmfYn)A3x&$-}z zBJixFsYR;jb;3T4@j=~v%%zs)-=g-DKlXW-l@GkkY`yhklAC%;bMPTGuqY;~AWJTq zc3A1MjxF24hV`*ZTd6?nID8-0T|-N!F>c{Nv}xK4cp_GGCV282OJ2R_a&31&6w)#F#WKyADH+~l zikZ?4rDl$X4$ii<>?mJTH4*)8v3RyzelfSOy5O^LCa;R>`0QNnvQ(Dxl0uw7QzS=o z%7zzMwrvGE2!<+-jvTacV45QB&*%FN=%%m6_&UX%<8E??yXEsstHDB0t6f6k0nzs_ z9i@lCv|c)M?b@Zy)2H*7_KrN>Gj!0e?QX@YAelQd{1Lq!(|5tsA9c_3#Tn@p;=2 z0P%6*#ZO=_e9VX6G++muMq3qSk80wSBdcIP<;gUn5^tMCB$7;RKC?#jwnscsFawSF z2vp8gCi9s! zj1BA*9q-}!-Uy3YA;PCpB2AusDV{hfGvOthjsz z)-#NPGiTU$$3>!u!mm-s2(W&3npzb3dEb0d_joz9RT89ZRZ7906dIldp}uXx%F>OM zTF=@wjy~#H^F*nI4}i9uK-SW# z61dnYy>4#qF#~)W)1L+0n10>XNzo`^I_c9{Gi~y2D~@lz)%%Wv&dso#YE9w90L>Ie zCJU8H;HL8y#6dd=n%!T`+_7_wftmN)gYhr2=R0GAk)m6j3pk}>35i$?*;g<_-lIkE zG*=@lIEpOPkxuakMOJS6{%&^_gWDwN*6X{_dBYIKbhm2-YiTKe=vWHp*ZSXa>ieVM zFF}l5?i$UqSP&_lj==Iv`+EvahsR-hncryW3r%r9lOj{EH)VII;PySBc$aned~w;9 zT0RDTE3fbi88(&8vLR&q9M)6Vlh6AKE0hrRXY!6la=LrO6_6Soc?bfytaD~{0=Jhj zT~`b*v)ZlVk&~T8=9ehoP7c0(^mU+&57v3K>(D|g+ge^W#u}iXL~+$vy;s4`_P$Ua z^}dM~(}m5231)jk7;|w@Hu#8dJQ+0(I+>U;Uwp*;km>)wti5TJW!Y68c<(v)-gC}9 z_uP4S^E^hxix=@CUd+RbDI=%Id92E;R94oIHD#(wB}zzW0)fP!77eHk#-L@47ma9) zZD?es2AX9+AdrDx?myi>y1ndXu(4^d=zrDc+&9FFAq77iRS_8(Q^wtApS{05efulG z;ZH#2%dQEDqB82ZvY08k>FU6A>sR|}5}Hk@KwTrA<16Nh4^v+uR#0DGEr9as-i}6@ zMk)P6K+i#fJq#6{>z^JlOVd^Ar9kSy=a{75%kpP&?M>`CD059*6`j#mQE$Sc)Xe&R zvDm3Lo2^dkSikvEjwfx9KpK)g4cj;eb&FF@Q+&ty0)|vk{ch+$EWomN?%lvvBV^fr z*@^xse|GDOcK9o@8$w^d9jYn;!1(l3h*YX26H|IFA83BE`I+uw+Jx2WloP>U((SOk zwUPmq-Ho0>ph6T~_xiq6aHsqgw-srr6W24Y3rl;sJlAfuwwF_>ZAYa6q)SWN`|Il$ zF4VW{N21Il6~?{?J!xr2WWLdf#@#+7iDo0H9@ z%aL8^+OVCOS(3Yxo~;x78nGUFo^SS+zSFrZBOXg4yk+{oBop5f%5&9E0c^QcbsS6A zZ02Q&M$~lH6itXa3DZc?vt9;ZVx>$k*vMvAbG2bf&wM^kzv zy(+ySz1Hg}gxuNcZt{@)&Y79rnfduUwN&cPh1br#)^6Xq^76!`mmfdAbMyJ@&%gB2 zonk(3-LX!mMm{BMKazzOjT<6+qt%YkZ^y0A!_ICYyTuW38Mk@En(eVShy9MdF@d$#RZ1(0-Xtmvk$WJX=*P_8_or8d)fr|3IxxJ z*EYtRd5qiq+$ub3ht#=NtJNONaBv7TMI$_Zuss(#$tVL7ZrI{c!-i-cSJw%vL^>iF z>ZA(ZMog}~sfCGynmtR+(I=Q%T)9)J<+_Qfm<>I;=_aB}n8DYk-?b6iZ zVrjkEEEU$)5~ajx@x$DJ5hf8nE%^0^mG2cNdkAijLe9AYUtRx&=OGd7a5@LgfmT#>)Fq(%y%EJz|#BEc= zWH&HFg}U_&D3$vASL)fv%ohE}9~%ekH)ahe(8GmT(N2B` zTFikV%kXF@PyDes%p1&!@j)ohA;#rnObd^@FPc5gX>Arc92PTIPQQWHH3tF9k<-4X zz)fT#4X`;uU45W&@tSJ@JEFh@)k?Smyq5N{WLNekRSQ^5j#~wRsw4!H-jS~t@ z2=Y+an_ns$r34*tScY*fVGiSk{DaBT)u3D^46Ah z=C#)>{=K)Y+b2BfsR_L!*}Sz?C>7P)m830z2S8UIt39gY{yq%JHsUPMh)@Yw;JC)H2t6)r>$W8#d9D zDl#-K+TtYrm1^~FgTK6rb*5Fgw(BS&hL*Q9(gr}7-@w!%LKqXxgK!38udU+-QCVHn z4Xy5Lw8c+urlA=etSB^F#Z)OLNC)(BSc?1dKjpC^l5A;4*aTL_6KYwSNJY^^A)B3O z)oSH(FcF*_`#n+*(gqzIhs+75(6JAV#zfYIlsmisA)uCRLK;Lw@8c)2(gjg<6oqB0oX~ae?67oRKyL%$tpvd9%@H z-fRfw&4tFoe*@;t`skFSv2MAA@5yka1%YBuK4IQonL3-({T{drg7O?QtAj-CQKzxpfD%pAdB5Mlj#LbY@NgM8>i*;ksv`omDb0Hb*JCv)K27c-esE+-9o(f?CC_urJd90#0}?u%N$ndi6g+VhKe z`uQ%tdatfj6pZgl_XfP+M<`WB+q6#5s*SN~k98jl-#5q-Y=R-;UmRioeuH65XV;&V z+?dNN~*%FTVil9eqtS&nfGO2LlKj`XcbWekE!HCI%_! zPYW^}l(SSQE107#O}9m) z_??cAveDSOye3`i^OP)IpWAI)&8tnfSmF)fMGAt7g8qpDh=qtTVcSaFietL6Y;CwW&>gc8&p*BO)*AQ1RF?hF zcY)kar=6u~`2(ohuME!|zT^2e_EAV8Y`bxx+t(&#tV9j*Ph9 zSMbBn#WCidbVYhzdMe%RP273wTKnLw{r2`-Ywbr*mfP(o-KC``wfXrcy5I8gmP#6Z;{h$Y(ECKb21BcQcKZ-+F*uTwDKikZfNy@`m)orRlkPd>D zoN>glXruzEF7^o-3iqk1LUohnDAhcJV>6HYCqovtlD+>I99Mi@G9_2aa$9*>*vbX3 zTE2YIR#lH$mN&ONv%J1O;Z2;VK|L2%Gg+7cGievz=YsyYoFsFme*-dXX_4;QR)+ka z!5i`i(K`)?V?q>7iGmB5oxMvqoF|x?U$QB+F?5T$P)V1Hmmvuf6sJsoKV#IBwlV?lFswlgAAjF;?D7^Jvut=a@4L4=J7|CqI;xe z``DmEtt+m;@l%Mj@$)JNYw^P943D@QG6(wzCv>~x>h_eQ+mk8Ev52LVTpMa!YgP6G zvg-mbE6Cu;h1fWArA|?2VNDRPh#?7R=oAFRa7-Jk+#>O4xZq}Mz;_=!A4ORn(I*lw zGsUwkfOQ^O=ys&r{NGGaQ@0CeHg(HTbY}hU=?flH+?FePc1eO8D3>~!u1hty!n~!T zS7uDDraZkS+j*>*$-Dt|)9Leh{6Es)a=lMWd2W*?dtSTX!ECGLrMYmuN+v_R6Pxln zW8HDxau_qR#0_#$ZLnhr9WNclq8Frd3xCL+P($8@VIIi#67$USTZY^GVYy9hcd->$ zQQLAIdfepNZq8*s&LwZ&?LvQRF-nKTG(6$zU8B=E;5M2tZPL}O#YvD|ed%ZP0i{Z#?uYm{QU$V2qQ8Hw@cmxcPntS@)3g3A+^`H_86PSaT{xS5m7P?gz- zZnfaT4IYtjkT7EfpUNVON<%pcUKAn){aK`zYD)P`Da9{Co&y9Y?;LNpI97=tU-g6f zgk^K%4e#98#)*X(m;P9S_PM0&;4<@`@;DS`E%>HYOdGh(eY|0~6ID=`15ik^lKeG; zN0nU7COKq3UxJy7H}62B18^}(QNwVjO~t!y6NBZ&(|d@uD9nneq8J& z`Bh#DOmoTc{iW{e-0J4$l49G{rRvEf-q`H-Y0U74dkgA|gGFrJ(U}~5^p9}+*VDOP z*n*t)-H)06Cm2Z-K{=E&p(*EqNh>LeTl}dRwHwLw+ab{{^<{@4$Nv1{;`++UQx0?9 zw3YC-j|?7i$>yG?xxkqPxR5qbgF3?=gMPeG;5T7Yx-DJkmCK&Av3&0K-i^I;=e$Wl zTI<=NSRm;w*1ENciHqLFZ!#7!)@>Axj;`K0^=zLpfD#R`-`J+={!Dk%EW~;Smr_+nKS8l9qZ0s%Wo%E*TQ;|c&+~+YATsw67o5w0-a6tS=$)T~v}V#txA<{bDh$yU61bO$-l@9pjVpinHs zoh*S$kPS`Kg3KsV5$Eq16jxAE_b@gb#_d(o_Mjyfwy>>vCQ5H}MKqLBsZlJx-SCX~ zrnxYA(UA4Gu{{L9u>+}b71s>6?eGF*1k_17)}A~ zI(b)sxfDl*TDx4nGUut64zxrZ3R_fbwRK2~(@kbN8q$4T8sYBk} z)u4XNUZ1dPALkOvw9zyS#V(d>G0V>lAgVj!(x&3S@7gzZcfXHYI&Q|(AZx$n!;SrEm_7F}AegB+Q!~7T=jvKO9pM@qAr73cS1RA#ZqIm1>M9qaxaVl! z*Ie0~1Gwq%SeKhWEv{>deoIYqq%+b1m*TgI-2o2@HsSzB{dx+D&a z4*iv|7k?h-0}DK&Y;b$q<@VxcuW@r9&z4#^Ju#8b<679{-U^qUsuKiw_x$$xOP8>1 zluCF+9{bH<_i#e%8JkfCZ$vZ5$o7t?9>*>2sc7cIGIpTnfe0h*n&GY|s58$cwv=Pu zJN5pHmR2wnqkZ3((76F%W}XKrlX5~gsWXuS1=-^;AoHG`1l1i^bnkFeO`VqEwwY)D z^rY5m&9&SAz_tis_U}Sjzo--Js22DArHBgUpR{1`oTpI|=N$VzXn(?Gx+e9cUFj^h z!p}>$d(9hHn&ssAGiR<{OKxwR+t}MnZrxd5Plg#kQz#^BYg65oshJrqsU06W9iQDB zlWhM!^aau9l|D^x7f&r9_iLEZvGKQK!RMYZ96k?&y$oPRKB8ojn{NRRwz>2w{8gkV zWwT-m0>Na1)$j3FCY$$!^?pvX?=$FMaWUhO31C~6=0c+j$z;H>7IplLOHn56=_qTs zrmdC>TEJC$J*Hq6ZO~KC`5Lz_i4R!Za`*F*{oU$+6mu(x{KtJR*XevE(TcpT?3}-H zDvMxGfP%&TY<&IMS}Tmqcl0iC32nrQjNa^bFz>ubgS(y`xC>3k$pbqD z0t|s0O)}c({R`WZ8C4CM^9)>fmR1Kk-6jj2&e5$6S!spqn{v&CZS^;hoS|8VNV&sa(@p84u?y48=)9mnmP(MdXN z6djJQ`KOJqEk@(vVxLy+aJS7demVZf1&o+W$OR80F_%p5x>!Rt^d>@_q)s=Y000$R zhNYPt-no~W#>UR6C?sYe_gEgNoD^P{{cr<~$6 zm`;1L?!m-5Gq~#rKWi9J)pdR+4S=x?a!DOcQ-`PoL4v5B#~NUSsS#0#sbDQbpp`&S zi$nzqH1iHj_Kka)W3{P4WgH#O;2ph;hl$9;*%g6n zyKxL1xB8A^hC$!nyrsv>tLVO~={7Wd*^+4*asW^81oz&)ZcnF}DspUh_+MA4a|@e4 zFIPc24+Eb^|3Ox4r6AMu+^Ng|oH9jB>v)I(GXjO)TvE$SXR@Hob$z}>(XMV&+tgIu zuzPPt^AvrVp90G-A8am!(5p;cEn-DSjtsOF!@WgwV>a^Z@wUxbX-Rrhy56h5t}k?2 z^;b(TX3qB>Z9IDQ)vHnhp{r+J*m>c_7q8wrc<$i*dF86|3_9@f%h4J1hW9H8W1@n8F>E%rW2HaZFdBL6jx*_xr{IQ{;&7JekGPZzpqd1J$nE6>bIep>mU+L&qe^iY z#)@ZX06^86^Kj_HfVzw$u&&?|IY*Utyqbmq7m1OMvV$1m0AV#U+^&~=de06}_xje7 z1)XYZcan!&E)Q>+H%AOrQPM6OxP%iRl5I0u^!a1wHNz z%Z7W#LSm3o9_&i_8n>d8Jjz>8`{AlKr`1Jo z%=lQ*+fZKMPxp_l;DHR!I?;17{}%+$t&P*&fS{RGxig8jMLn^a6T42rmJ_|i(e576nufAF85xY=G^y(xR%&ASK9gWcVmHA%XuSF1N~ zU%z^_ce8h56W*~XeB?(*qrQU~z@s#$vD1uVUfjb8$uS<>n2oYe6?$|B-9%?ck*&6< zewv*bev9%HiORCl($&sw;2~;ZvBZk-lT5qbIeFL2AOooZ21-_eWnEB_EI_4bxSy+3 zKBbY@J2p3A+78F;2ccoZ&{h>g;~vNS)mrVEu4~&gNZNr$RPWlA46I&7hBg@(npa3H z3UZRANbI9hrI5?=uVS8t62FBL(u&A^JhL|E*rpjM(*o)weQG4 z)hXMHj)&jBz`>fuymlxT(&ju@0zXB>+Dp~Gz#*0?TTL-rQ^Pj?{(6d`7W2N#!xmB% zKtB#i-Zd4KL*Za)ZEd^P^Jh%#2e|Ml5647hnv@viD{Io^U>nfBsH}$zJ3C6FGF_Us zZH3=;9xT?;)ReL^JDXLq&&W79hr7F@qfKAyhpVnF|-}Stu~+n zbi0$Q%-V`M*#LMKoJqE(QfJu4#_sCsHLX|}1 zT9Qp)QoS#j@+YM)NZ>z9?@OStWJ;bVnM(x~)mws!X>K%8`}Sz0c65j8r;z*_0j0f+ppL+L~FcYVKi_5=r38p%k#{;;qC-3Se?xqUKLEyP}3AAe~!@~&E-0R zhi=KnjA+SOBb$9_1tsP+1&Om_04rfnxUjgx6rBd_0E&2LI3M5N4IuW*oRKc^$iJyF zS@EQ$#OCJ3(%SCS+}!?lCR(%%EO0a+;-M;r3cV9Bn>luLBae?p>Gz?WkS;jp(GyR?@IradyGYs(f zNlp&9;Qx9cw^`AL)K)pxl@%q|kfdBGT}vktR?a#-xp{=?V=!HJjK>Wf-J8gxj=T5n z-77opJxk6MVW#OV@~3)^a`b}Kn@;peYTUvO3FXYUmdnjz@d^jq%fxv*=fkjFfh1|0 zib)-Aa-F(GFQ z1vzjmOYUSc=jHRqi$cd+ZTfg_yme}EL`BtacN9<0&w3z&u>@PZi{zX3CM`l&i^r@J zicA^4PMz&FIc%s8*4O2YvTtoF(;#$!Y_5ueQXpr4;LFVWz_j6BJQuH)Ag@n|n%pX* ze+ZZ!!{rY^GAs6wc0Gjz_~lfpp!&&qK+J*4~5NznW;vBluCtyxpnRwhyB=G+uSs{!kBd@U3DbM zyuP}6(Y!b=*VA(1!y(So>Y=Aiu?_18hucd>2>b8=!tSxz$9Sq|Qv~x(u^3Pk79e%< zGIicEagn?1DVLa)(Eo9Z*aHC)BxT7hS$l=1W|Zxm+cmKc94% z7P$#SOHk(#bpU<@@P}+zaG_bSnao?%SYD*UD2CG>cQOqy&fgKl3re zgFPMnyEh?b|1%WRLcw<;vEL>! zN8XX2a#Fe6AvNX^4&t#G=bQYJBE)-t^&0 z`1nBzx6bzRaB2;b79@#;iBne4GW{J>fwZzIen-6z80^hj%RK9^*Dw5r8QAgZA?$sI;xcH@c(j?w(sX8aU1wA%e{{? zH}be~czzl~I{LfA$~jU8)?RbY|Bm#6s-cm9XUa4!<|l9 zVge0+dB5J=)2N9KCL4$&u&B`VV74)R0j|91qxQv#0-V_eIG@w;q~WId7b=X}!~I47 zRr=qg49A))(zbLUE%h?xX0w&>{hie%Qb=1MtZCU6|4%#Do6-8?uHu2Y&+W|3&5fr# z#x`gi=REHdXU!euc^CrHp<5lZ4!5HUOjMK*;|scPxS8gL57vs!3t+F|>A(w<<|nT3 zgPmmFg(#mkc$}8^IL0i(+2>|#1wd?6f3}c>-m=4hK^-j@CONdHD4nE=nei(iZwHxo zoRA@pd20^0)2a&e4peL&u{f}tNmxW-%*#oGz25y3boeNS{}@7 z09;HPsA;$<#x#ZY>m6ValmGG18d#H>6nPL%Hl}OSolb7@_>SOV9y7L|y|5Q#oDYTfHDWnpgNK}83Y zxU#-#xCd_Oldop9nRDeVm|X|BlAvfpO!V;MXT*&2K2|(`_O$_ius9A|?`0Nq^J3tW zuoafghO&xP!wAI&n5l5;o9tyB=d~Ykq&L`NLx4IwUub<`M`aNRt_@lea zJuqCx>tAQ)so=Bd1e0BO8lk4W3b9{W+{z{shu&AnYDriliTuQ`;3L_^WBV6 z>_CzwgFczzF0ySAah4j)?>gP(<;J`kMGX#!8k6~IJ5%MTszFX;@H}~IfF+`+4)|-$MCyw*r*7r zw)zr}r(P1xh7Ym*v6p`QUs}O0*yNwPHWiGlvpNKNa(05DM0Pd_bNrd#D-dDf6|GCS?*~xV*47zt-z5Q_GrKo;q#(uQS{@ zGs=;~K(^0TGzcN$^*Mb^`*+{sU$0>-s|re7x@)+v5G}3G68s+X&d5Pd4)tUPW`uLM z5-`)ZVxpDEX?iT~x4c_(Rb)6(?V;g2{K=Yzv+l# z#FndZ*GIC3yTxOnl?L0(rW;=s97m#O`V*Z{t4u(`|F1$) zN||bg8E!S^1&+*$wz|?(c%K`T_9#Pfk^t>^ zlCyp+3%WQ;cy>=oc#dYAk7hg%rT$D+t-qP(FImWBpJ_6XA&hu{Dzg-3L^jg*p^XqC zvZ|_3$F>>l%G-{Z`#>s3q5uUDI0P^0b{PWhmVQw-WtIfY*Ia@ta)4Fc&U;4OYHj?& z#KcUa@v4Vx$Sh6O6@-14Y3yacgfLS#(+KH|piL54mJ5+)pF5L<)oYpoGdTi?o)4D* z*6pQ`I$LHLt!|X_FzS{7PM4|H(rpd}1c94r^yjPl_^rsT-fPlZ(%aJWy~*1vtRlU1 z@bKX3)yjpZj~`dwc=DvO{rc+_-Nqc!I@(3%f%8Bw`~{5$@AyWCrd9>a$t5D;FhVQ3Byg&7!%pXOZ{YSswXG)&R}`{!&x57uG`^n z^1sf$#SaL*{qv%JbJ_G?5X|QNc;>I-nW6;80m+`;n4eGkiG-3K-|Q6khm5w!pR)8(PQ}uLu&vr_Rhg*UD1D#!=+cs;# zs|jv$zeR7|Z5e2nI+K%(;#)!11&rx84KEvbDpl-JpX^`ryBu*OQ|A#G$KsVjB5mrC zm{kEPAuVu}6Jj)dd9ukh{z#vYo&)k>ma0#iy8%AVU2)fNuXFtQuf>J|{@0FR&5^f# zTF3$~_j#AB-&)RH+<9*=61xQ4Ns*ZAI26s^H#T*OrmZzgne?I8=H7cHj}VMHS$zWD zM(@D$zNHC=CMMKG4Cef{f{_(CX$I|X^b7L<_XuTZ+Vq!9Kk~UtQneIeZ_myyE-lSr z9jOK}?JhM`&Co5kA8Xd$|3=KA;BdKRdj{}J)6=5pXZq$5%|6y^8v}*Ij^**&IYJ2n zUN#K(%r;oH4CR4n#x82yL3nxA#G0%ktTH+uey$Z#ykoczd2DSvivF2gXy6-m&G3M2 zdzTEilnD8QdeUI8)1Sut$f1tn>%#%0{_lKj zM0#;Z;5Z1W##pR>JoJQ{!$Bi~&zSzJj0b-XHH<`Q#?kg&IVER9N3OS2o6b*&TK1z0 zSzF{tQ1n$yF)%rlrVLlDU?Pe_4Xt^e}xNh^O_9s~#6UL?$jKk^h7%@$}Ilk}Phskm7yTZsH3|e;Q#p8<8 zLZLt4tr#}{b{6(ok(bc`{72e_{?H^L_K=1mi-SZ8j`VS^awhME}1sh-4dYmyeL2y(O z;!=-sKo3Rnf2az?^+;~XG~og#0J1eDunYl?Z#0q~%$1_)jGUhEJzXcab^9*!eD*>G zax`lKh;0uWm5U`o@TRDCCZmY5ziNFNa$qZavzekOHsog+5k!%=Sxa)er$CAeuFwDB zz)LqchT%%(CrkTJf(quqRZt46gbP=8Ui2)VaG@@X!VWivUR>w0<9)fJwp-#7J}+ID zUJ!iX)6Ypa@|UFxtLO9b%uK!}Nu7M>h}Lw*u#c#*bQX{Ad5!zzI|D>Ce|&immumF) zlIq7U-by4ADQbbLjsZvh%7o+O6sq|t#itoxHZQ~-_7_bVS5=uy#DpAGxY(#)DaG`u zLIDNY09U{Zz1|Gq!gOHT(ln}IqR0TLzSl8Lt$D+=L`7wj>RRM#7W=U$NiIbVt3=l{ z982+)jO`K3f^}v9ZXdZ6)mTTr!S9=3rreUwav5&*a`!2C z&0G0$SxG6UZLv5iQ-3^J(LK8MS35E(-96>5E}V8%|7~0_m#vy8lI-QOv-6h41=uy5 zYh~Sfdi&iZ61Ufg#Ybqm7hm4w@ba#?6P}h0QF=awTY`TAC_MP`xxnWPm&Y|rO9wZT zgDb6Ts4uSr(7)5`qdTp}y~N+(KE#$5r32}f^iXtU-ZyT;YsMwGVI06kBLzkO$SD)i zgVwbHVVIa68e}i~=6UexQF}$7px_xdSUaI>uUMBH(@G|%U@|Kv5Heh!%&4fF%(e|x z$#VU$9m_0uo)YC0w+u>nAukwX80gEaxL*<*R}|ICrnSDhV}}sCxHoE7Wx6tT6^uotWGs z{u(Zh+))7L-F^WQpMW)!b!S%rysc zfUtq0wElSyD&x8sEM_1UbA8lHYohO6Wex9L9yBuTmhWrd{k?Bfw7Z{D5}lpvzNM&y zOBGoDZfH_`)3OTxC}Zj9m#Cp|KdH!{zihDMin^~mzD6x`$#OWFv4m}m-v5u%pT#-Z ztkmSzag*D}*AEFaI_gqKQXcQQK5Z}t&5h^`o-t59_U?rz zpAbtKInLi=?g!>{k%E2_C>m2Cw^3vg1gfb1g9+df{tkeXz_;R5)w_#}mxGxE-th@e zFt4FosO@N$LF@c`MJkG8LdN}!&Z7j=hN^Bj9yEPbyffe&`HMI|t#dqaOL`!^E`3<~ zl<5CjrSH7?>cjiD(T+@SZC>Bp;aDV{{y6>k$+6C%)*Z>s)yMXMjMkeR`jDf!riDnf zDQidayknh%DB^dz_Do5R-Sn@3NRQ`4zcUn(6>_lIZppPtItjT`QFuVD*_!I&xbcn} zCiF8O;3|sb3UgQeX;-cBfVofwnJmBilH}VTcIy@JIL~H zLPk~9pmxDfsl$Qy!jcPvp8C&S40T^gwzneMtI*^dr(g72fHK zt^6nd@jsM4`1(s9xO?Mr_uMC&vpcih?kCHV^wCd#^w~!@$RjO&lS2~BFr%#}a|;XI z<3+@N1}c6#KB^Rr5qpfR$JjX@h2=wwe^fm<0v8kx{U7o!cQ{;fGEfMQU^IRx9Aoj* zF}QRCe(6)l7H zO=$O58kB5PpbUlmWJGM$L>V4`>WUy3vv2_fTzM3vE1L2Xss)i~+a!d?R2V8mBRc<9 zr#WR&jT$;rP1BhnIx2^TyJ10GSlY_M((*zcPF_eGByOv=z9dHh5X94ZZ!cWVotIsT2I7j(Z8)0{Lmi;fxrYayw~|+rA@4Qwfy0cI&A_UhTh)a~7h4{Gyl< zyb0S&ovBhI-u~+=H{1KnZCoOh=pHXOhkcTvkv=SphE3w5 z?e-JLN2X5v=ALr!yvOZ&Z`|gsB+gMZgz_Oa)GFg`E2~(s6koUG+ z$IPDMakjhz(l~CS{Vlv^1&>mSY|Pwyy$NR@K(Z7uog$U-5dYssw;PtL)m~;4{iA~O zFQMP>rXBQa{7qcT5nHRv(g#JSbzwjC)ZdSuI{WM?+LxbR**VzR-+$$e7azR%^y&Fm z&Yx7HlZfv~r(E10H>m3$2{lCY5i7`vAmj*5;{ZkTs6_mf@U%YtGH^{**#9hR0V}Qk ztQ~-m8wa^;Kmb*8E`|Msq1iZ*u+kX?1J}Sjq5z5>Ip_*=pUReeK~zgaU1tTI$1FId zi1O(pU;*xZ_nGq+`y#)98Z;1Hg(*lQa+Mp2Ah4T|a7lBca3-P2j0p-bgIgL3bVGp# z6s(21>N0OiS5rknkA|Frp&(l>5l9>xaFy0X*M7_yFJhA4l}vuKC;E(V*+xU_&8*MN z&ui_;ogGbK%-8(m{fc8f`$xOmM;8?a>rP&$=lQj`4uKbh0!_psVA1}J+jfaeexw8U*3pdc1zdM z3X{_jD*;pXe!*}zsk37$dDGLheZid8=O;Jb|C?AJ8}Xb%DpfGE9H(iJlnG;z7M+~; z>cS)E6?y2r()xAHjH7P#%Fhbg2UdPSk#C`*Y^)@nY%x@wYRf#C;2T|Jn8AEMNRaC z#}XF(hdussW@o3L+Ymgwzt6Gztkjj3rF9;ibHqB)idHvSV>61hxy6;mjSX!<>2z{h z?ld7EW{<{i!#L&JXp`N53ulzGKh|lo#Gm0^Z0oXFcc+R>O--1dX$2THYn39*cI54J z{f<~1E5AC=7T)8pkCU?r!G1WE)bxa}Kwyw;Iy8wkQ_!JVpGg@?IE%hBxeyVw6#afC z6SrRomOB`85(&SP;U^Psv0Er+?di!z0~w-q$w&TCqUJ+RiMbOL%Y$bd#dIS+ZWNo> zK{B-7t*^<}d6`=+4K17Q&&W6#!61~2nvrt@jS5(-|94eE3i*`U)GBlM6oP!ll;uau z3Ego4<@QTs-sRZ|4@UEih}mr4b`0HiRx|OYGBrTz1s~gpn~wGL;dA~QX);E+%e~a5 zbD5r7Eubu-w4=(EN@uavT3tcRQXm&b_L z=@zxQ!84rm=48@R(nTJnwI}Ko+^=JXo(UaW32wP(WDSD|YCUTIjEu4&m<0UyH_8=X z#Uh}iU+}4ucMLaQP$1OJW~SEAq0RM%n57H@$);lzb>tApQI3YFv%1%E;M9g|*wERs znW7<`1$|D4Kb8J6<^Zb1YzFJS%!SU4OQngdwXid@GcloUt*@+Tlt=59r+Lqm*SeTg!lb$C@jj(Z&Hg=eEf9CYZuvK-~v1)?;1v_O| zW@~(&xeE7U?C&Ks(YRkifNtPcvEbFRbV7tUq&LYe z>t4)sIMMT0I(fe|VaUmVKYs%G{={^rV^7#ey7xQI+}yE^ib4*fuB-w7(U7$`-XT?w zDa*y5k#@NKH7>1>2r_=O@TyRAHOBS3Dm&jv8r# zQBP4chSs;Yx0g~nx3ueGy{}kXy#3BffU3=uuH6bzai^&3He%icH&^o+HtTs@AE@n- zehjtxzSuVN+asB@dx5PZ*>zD;l2DLHAnf}JQcmO5KCyf07#q}uH$KJ{{59<9vi$~s z*AtAWahze< z-tRJsJF-<*)*1co*jrWNiKGACHx1RXf)q8-cUyrB@u$*y3J!KH{6)O;!;R;#*2R6Z z6xngI2}#QOQIuUTtQ0DhEcU!kw)1Sptxo4u{)6sGW~A|cnDK6~AL@xD=0?1)M!<|8 zh#Od(S>IB`)H;V#vR{M^QvlfB($cN;PeeLDr!VoJ>;5mD&eF_GqLI?^4D%8i56cbR zqAw=V#!{;cR@WdI?2jJqW*MI0qO>D=<2IL?RW>!%Yzh*y1V7CLKg|R;HIkG_2l>Et zyNT{MJI%w6gHz6Q=;BTsY(L=4gMJ(Qh>fOx?YaKTGFXaRzas>9nfnr)CNGYK%WGBY`9{)me`*&=(oBpmQPNy zoO|=5{GvbR)=M_u#Nwd_3!i% z*FDDi0lpa6w^|k5a=H0UE~UgivE@iL=pElrdENtqLn#9$E&g$+6E>@soDe}-H$&6a z6qGPhY5o;9|I$Nv#{CDWNd?&m2i;b5<8vycCjQ~6!qhrtQOUD+G?*(t!{2w zhAX*>Qnt#^YAzky{dFu}>9bx9mqH!k(j1oSPBAN=E3onlJTxwdR-~8%zbxng&dYut z_-QSs3=blI#;`n3q^88+08o%6fA1!Lxf5(#c*dq^n%|pdNj1-#T6LLSn?BP>!DKgr zWD<%ss>A`XWw;U6MYkwpuiAs1E`JvH-8ww(Y)Es`eGwxsPB*K?>pPcwm#<&P9Ac$# z>cm{dfSad0K2THA5E@m41QuMVACA;%gY&G9H+YWArgU63zh|CzJ>dEr>D&9%!47N4 zVgaIRm~uhQ`8dh}H(bfPV%a57Z0lVvH!lmU6pE=q!YFFljAn@8)EqDFQ~pSy=)&}> zZzvV&SMoi# zT$eZqQZa?4#Bs;pN`Dyh;S=ws2?V=E}y#f?`=0 z7cM?)P<-5GpUAv)k4{CO!btxtVV)2>H!;>ZB23JM3$Hw;_Ij4uOLfEf2p8SiSn0S4 zS!G#o4l|Ors67$HydRqIZEhC$p<;?&=OS29=I8HFXOcS8f(db2DBpel zJ0pfuO)VWd#aTzAz(T2)>hW8y|))%%q5vX*^fN9rAt5gYFB_8MV z6Ns{8zFL(=xz<17mUl)vCta0Z7x+MWbouh}g8@ zY*>hgy0WHG>N&to?8_nIf%El?h9eprpH7JYPmXZfaF#R^CqnzFAP#mdg`))X6$?R~ zV=&crFw||uhYZeB`;RS|$ION(B128{c@V>(*WB@Rrg7n?g#1&G>`=?luxMd0Gz)P* zf~L6tE9YipAWN15+OXvurcK|H*z$RDb`kV&1L8a3SDS7kK z`Q5j;(|_>FE3duvR#KcnaxzmWJW4(~aR!|si}T+h`@>HR&1x*kVfraTIS|Es3GvS1 zTD>-sx)^n<)fdOF!$Q6P-iA-~NyA>@YRF@L4e5q&LNoW8Pw1@Z6=E_0Kn5E2sR6w( zw@_{@*giIz6Rxe;&CErQ0m4lL)@FUIXflL6I^W}gsME2%Up6WEv~%yGVPC}b-a6lQXHU9l(froxg`^f#$Na=~#;0t_1H*mYG! zhm1!w(1xj`=xQy@QwPQzb^UvxNYn8g(Ta3kdQ-5--&jr10tmR5uvT?xsZv>;UtCsAHY*NboxgV^cr6SX&$B zj{2u_tbM#3lZ*DxIR3;NGMJs@h`MFE2eK`9P%9;8vzi#kJ^-?7%G?0Gq1ou80zAI? z9>0a!lwr>WDnA^4fY{Mp6OhCcSJjmT!|EoH3{;IK_)kaB2-a;YA7WS2bIdF0DCdU> z1?qv#A-aRr{1(E5YQS|9o|g=Qk5PyPH>1V%S|gUPLsBXmvY~O0ZE1uOgs=vzrZnJy z{tttFd5h9*ktg2O(lWcga`p=Mj4WET=k0X*0=sYszK)P&cKTJI!P4yErsYG*#lxVa z@9qxeA8F`xvX#N~&msujxLpU$$|>qa)TcBxYr3y*CIFOGYAtX{yX^_N+BC&1*xLZy zGTp~cr{<}}7S@gVS-CP#cf>F^kdyx!a*RcEGdGEdj+=S0qA$rj%`tT@YQu{1NMntt zWI(&%L2_ABO+S(2kr884UcHDRDVDjsErZLd8bW${?!n)JN%vd9AD(hu+5em-P`gkicr1e#VdlC+*)f5w`h&SBQ=C_&`0!N8%! zO8r&PV_f6|aSQ&=Lvf3~SZ&y#Ka}gv3S0el{>o(Y+XZptr;&NlFwM-Kr8AO9w%;W> z%raS(0aVql92GLmYZ%n3R3{S}F{Z7+@Vp{OmdW{Q5~#9*XzkaM{3Rdpm$X^1RZ7%k zhjDOxQTR<+*KLD&NY?>ZA*^AnwgSZz4vm%p4?+NQ6{xs@^#o9ZL6$K9vn(FzMKQ*i#>CtkSQM=uru46n;q6UBGOK0G*&+lKr|4U_yhHqK`o93?)xR| zAq`-^M`T0?Hds%{f7Ih1HS{pSGKlIWH6UJUnrWV%sck=(-k8X0U-3|aLo61A9I8id zei}@reWFyVpqjukzl0BT`vNzEzDqMI!yekUbq{cz)HHWJG_+zt_IQ9;o22WiuecWa zpX-)xqE;cv0UI@=97hNFe0zQ=fSK;zv zHFVpa=q6!iVXNaAIC=Jr4P~5Nm|NZoV7Rie@FkT{Xt??|L<-@-y`1Hj8Ts;b*-&h| ztZ*$=qeRSC`KNKcH6<0L%iPMpD7`8j^eWNJ3wN&FDrUD|-ZmKdM(MGm>r3 z%(s?W6BBzgrx2YV!J~&gV}12n=$DueJ$GC#f*xs_?PUdp#9O7>uZ!8iH zJu`{8kP3xVRbC^E_(>x|21(j`MsSA_p8?c9?tJ%=17#ZMe&F zGMliwh}8=@=%#dkwk!r_Rg_-Fbm5bb+7_&rxIk?hz@Q{^d4f)cAM5w)mSQ{T1%qRn z3M5(GP?5#F3dc+p!#$f2=oHW$WKK1G=u{$$h8FiI%+2n*L4C+u^k3t>6>NoMHfpZST7>F>Z$(`5 zxF878-KMTNs%0%3ivci~@M|KA+B=ZVO>7fnIp4(vT3y!^MX`_zQw2yA2kbZoaow!q zc|z6h0u!lf68-w(;`-9k#`^k|rb8(E|J!>LC^@e4JhX1z+HUQ8^1VK{NLcxk8Qrp;jy6-bWz#gdrwL8ja6!OdllsGUA68{@sQah3R9$cl7e6R=8( zEG9KAq98egN0NkHS9n`W*Tw!CFvtFP%Tjcm7uAS_?GLjXH#AYZB%51_MYt8x5>`}@ z1v4Jx1Pe|&3RknBjcv`^c@s$tXE*#e^yZwj7kK^?&TN_X^Rqk4{l!VTt5~EH2 z*4j%4ywiNp`IYKj)!JWf;}@k zmGPMwVC#y~2l|#x&M)%=YnPgAEgpMqg|=gy9T{mBXc!rB8dddLb-1{p()CB%;bv$4 zSvtyz#PfGh@_CmybE(E2O?2%8l1dwK+zJ8BaH%0Vq5+sMfJ6+H6rc+tO|mJlTGalM zSSbQ$5Gm3yh?GU#Wo6C9dUXm}f+$8}h9H>8FyDgM;tGw={&!2X27YPwGY$y6D~ zX^aVt+#(6wPV3YH^%V7?Alt%+o}D^>NUKei>D*M3UKrnx%`wfx1|zLWreM16yf(j9 zdtJUdVzg$3*C=!vG-14_Gwit|sDM=dYUhexrYjA%YT7Rwcvgtm)=2bw$|6bBp_BFv zTp=YJ6McfE*~dJdgbN9(l3*Z>pO`TLX@>)Jmtt6pY~36u*=fw-O7BG#hI zh%>Pz7kBc&DIiI(EgK69l*rq~7>HK5$09*JDJ%*^-jU6OXn86&KUf~?-kyMP6W~NO zU&x7^s>M}&N?k!j!Z@ZUFp3|A=(7@U*)ga)GPWr4kYiX$FzJZTaI87?RVZ+bpf_T% z#bzA(4DoHjW>b&1nWB0ohw{_;Os1#1uhcgk2Wo*m(r zN#*Nge+u3|#d6cQT?)MBfgC7Xys(8=5CgGk*XM!6XyOp@aZKU2jUbBeSnrXONkd3F z8x`}kY3*0dgNiAtY$hVns>mR{D9F61LqUsTrWE2q*1)ugNFMM^ysAOpl}$ramc?F`1kk8$+Arjk2y+P-Sg?tjIH&YZgmu-SEovl1pY` z+sAe}vyL8`M~AjWkgA$B4W)Gh#hfACe$chI28+apG>}Qrg#^$%ld$K(G|3UNBatZ; z3coB0j%w#oA*M4aSHpUeBn#!D%o!?&YH3S?md#6oVFbEhypfxZ)QoSY6qHukzcveO_>m3Z^6| zYy>il@bpixpZpm2!l%UUb0(SP#|=9#YWx*hiy!t>jU(Ko`Jo+y?Y0GF0h5z7;0oE8)#*TU7mKN(f`{f_)rj5*y#J6 zPL2(ozP%>f&H~U3GahahR>eaA-})%mteG@2*hmn-=d!b=r0e1?B+!Nl1R6^RBbh{^ znDsGR1_Vu@T@ba@AxxxXy^oFOq^D&`bO(btuiJrmZ_dzBCZ?4ntjLi`iD=FFLyeR+ zp$!B@L&M4z2}R_s?(aF5G?I4soP`vk*ykpn$JTu^S=}ayLQc00pb3_Q$5PpX3OKi0 zmiRO&VELsIbKO4mI{l8)vLDt1nRF>%be41s|gzu}7cw99l$@8EJ*YriI zuc*%0o`GC8U-=!Ne*pigo|2ddvY35>CH~|G2mw*#9Gx}3q@$=OVZ~fl1*Tf9*XyIb zy@4O@Kj1d;CN)B|#sdBz-J8zmMH!3BF0pIHJWa#SBMUFBHrjOPZmW^}nrmSAu%c`v zvBxF2iBLkDsmGr`rd&nf8AogLxgl9Y|&PD?ssGl7J!}H6df# z(A5=-1B%TaCIUg)sX`vV>+xIX=P*(xi8UG`747ipxvSOp7KbNil(};vH9v ztva?FRKLv15I0Cb14fNn$We>|GXn z!O~f=Xcw{km|||J(kx@qMGKPBfvj#QfKhZ>HgthzWSSAVq+<1At5y|x)?(Oxi1zw* z-LA*|!Gvi7+`y5o8BqkKj2`QYBs@C4-BUQt4Pt2ZYd;EVRpqhV*hKBZJl;5+Ji4$W zyXDkWcGPmS*#&4>3y1fgIJf7-sZ)ImeQTvaGged-?ilulhu2u?!-`43@SvC_Nx)KC zI|Ogdlxcxby$tj*!Il7x?E)8=3Y=25W32=00=y#cv=6D0l4hd#bHLLIgfv!3Y%&`F zIYh^}U_vJmIE@2`AHc7YVee7~PD>t=RG}D?Iay#B5Gy|{1IM#XMr7PL1m;$HL&7x_ z{KQ>;Gej~=JUNDFS%wV4s*4Yit_i%ZsfbrJ$K#T*Am_!OQ$G&!k9kxT_sE0PlO#%G zAky=g9+4j7BGhBqNM!uvV~>q*K6r3$ZhXV0O}oc;uZnD3=^(SBcDhQp0vf$+GeZkj z!`tO>JLg+g>WL#cyA_(>SW#>g0>VmsTZbPR;`!3mSTGmH8FdD5BE(&klX`4`#V^oD z1T2mr;#Dms2GQT6le}T4asAx3MrtlZKBzrqhMzIiwf*@@-L0*#P zBoe77s-_*ah~|jx<31xNDiWVn@Q+|)nU=Td3PW7D+;bIG!q3{Yu^LE61_t{gv|Ha% zL0z6CaT+73yd;5?CPN8mI@U&8^N2(z|NX#!CPVd;TpF&W$#Rrpn0z$9%$#m}&N!{= zhV99$rDF6;&L@Fe_LB>$aX^vcCTUzxX~qAv{Modq#)_n6bpWt zmd}wP{joT!3g1;Rhb*Xfop~I&XCfMO1|u44Nhqix+OXqhaR1EIOtY>Rw*lLNYH0hftsIwO~C znbFHwFHZ(V<}F?1P1TMoR#J0fu7^irU9lX<(6ZFmZjOULb)<{IWU# zOL@86W@VBNPB<(0xs>VgNgMH-bn6?0J5Wv>IdbH@{s2}`J=GcoT8~6l!VwlO71yG3 zeY&U)&^1kB6FszFH)0wHO7#9AA_gg$WwW)-@pvW{>m|yIr`oQ>3yx)C#YECHfK3^> ztE4FXCgbWl%V!*oQS%<;B`lN@?R<5O-1-8R_Q$D5ux%3`03gPkIr2cRtBa~L57g@q zFfe(dxZBo~6p`|+T>48*XvuT9nV)6(6ke{KK!kSSQ3-7XM@QTXFU2&v+T2MKKH3V69AV(_W8N`Lg zp&ef&ZhE7lI^+bwrL6qVhlVB!u2ba7UKHyqq8v*ojFF6Wmq#Pe9XT2ivj!5fWa-SL zV?#(AG(D`W7z!iHvIsd|kgPe6j~sS2XxC$;UeOqt>l3kI(umzAcEj(r*U-ACKI#Cq zYr42^XlVCXw}MzUm3IJ;8Nt@6(r>0fcSS%7NE)JoAyW`9R%smIEPb4ppsef1lT$=dx1FnXDXsJ%PVe9m8Kkl z<<1$-MoBLvvC!wWK67LY?9b+XUaJWbnn(XOmC6?a>eif;B=bI&#{y^N3?T)th!$j3 zuP8G-DI;TH0m#W%-R2kt8>Ipk2ztwZkl0;5wrj?zJ=pp(W+oER!AfBwS|~&(V9$6@ zThcW-vnocq)X@06cH>%^jdThQ1AJ0vPyK$5aTea@_dHa zlcI73sJlrBz)n&9f7zUcSvauj}QBBvm`u4xiKDZ25fMQgafHvHbci*39O)T7iB z)Me@!>Vwo(>g;siLwnOB$&rbPsSjK@eBs22scJn}A0D2%a_QMik3BZE{rRV!zj$$K z^M^h(CA+pAn~JUU!d*9`XGeTeGmSHe+-&H<&BUim={;Lx;L13@W)ii5ws}J=-_~kS zJ9ci0Zb*PY=5{O-6AgV}$btt{;L&NUeFG%Yt|NM$C*xNSkJz~SYY9_gkU&Z@ zXPm4G)q(~QlK-nyfhcc_v{sg7R*$I?=SfChHoNpcRY>%)#vnYTbDv;w>%}G|JCZjA zySwH?yWq@;2qyZ^WHQAxreY>DC#y`V;h*t?pr#X|;#d>Gb{c1aRDY%?Qz)c7%j!yX ztxgEgn2~L!S8a_vxq;^VerJ83Mm2QuNeQ?HPi9CZ+=K;)1{SFjWm6NrvWMPkHaLN&gwP7A@u_a-vVjZ;&-q#NkAHv49|1I?$JPN0%UdsOU znCBy~FUf|pPg3~3-Ec@(Idl*PIgbC5 z`ZMZxaSyVnB$gv%#ACV_X|a;SQK-9A8bU*D`@Fv7hZoHD4-d9Bh-g^yg=t)NsihK< zYOjq5tl`0*cLhA&^abx<#wG{N1<~(5oj?i;BrF??ye8B<0YnQhZT~vro=2`wIzNo~ zFW8=7c|R>#cqGD?FTa|hi`c{$7Ko_e7DZuf^LUI-jqh*7-~BDtgT52^<4=(2b~lsB zGnSRF_x9#Ro}b81tP%Fo$~V@&^0p)9(rkUU)O4xmhucbT<4HXY^qH*!S?2`iSHBndHbw#jmWCVs&F+4X>qk zk;SEFwT4IUP%DvUhBj5mljIUo2I>OhR2Cp!LRsEGiDz_cTS~L0E1K~$cwfOqxo$!F z7A>j@hopa&rd>%=HC8!H{QUVHnzL86j}gV~k%Y`Y`Kz$$15V~MekZuUL28t|txA=UC2`C*ff7|{J~S~N9Y z);CD9@K7(bEL%}o@g$7yigM|l5FNv|vUyB%_RwjP?gq&bPi3+uoh9>^Qs5U){M2H& zHP>-_-a=+tM+em2N}N+c+)&l&`1JDBuPdH3-|>h8CXnUhwq80#x9ZJ!t#JC*j&3Mx zfK+Ot@qmpjQG_KV%D^mp)E3eM8q?!uduh#!MRZj5ft$@6VzS2rvB8QVZkq^M8m(MY3i&L+zmE2|xPhs`hNLXz$#%&E7OMWhdw6?1-u|HgkP`5YbGgs=Z(? zYPpBO@;Ydxl|$=NoAR29$^QjZ4P+cqqO79bWYX0 zE{PGc1BSmG9{DiiCYd2E_xELfoh%q25j8LgJm5Rqp`R+`2t#+bxVm+sUfn_zG>+QVA zOPpEiSL@BJaD0ap?yy)!mdvvb6Q&g=I9{MLlFUHT(~yD^xZ^Z`l$G=S@eR7BP0|}Cri-k{fK*Ar!S2UIug1l@n7_&(3$sAQ`WT&h2_NE(& zh0@)HjT_T5`MjRi*U$2@R&K7wLvClAB=W`?>PYZ{n@nSNc3CxzUjcMgHMco+MW_k1 ze2|_KT_mAF+K%LgMNLb;Qa21q?d}4#9M_UqVNKq^n(N5OtXP$deu=>&oWX3iByKZ%j$`BL7%$4)#%8|uziP(KD%23+gi}p8zESyy%%yjfyco(YueI28pX|)J^(vsT&5&d@fd&#I(pYQ?tZLW*CewM^ zkJ-GK!X`(Vk;ERKSFy3dU_N9KR!W7Eq;Ij3SQL=JvNCwN7kA_uEsDZr8#spK(Ms+~ zdURJDrgzk7D4ghW`AkN~#;DxQD~#_zl$8}OE*Ybq6%@-WNlas${=b9yM3U=xBi3XO zP>+#XjYpZ?mF?!%%CtGOp*NB#DWys!l5opWCmHzppn)7 zrArLjNH59Krn0lDz+kb|IafKbqd^I46S6*l8!MurlG$V!GFvG#;ovIUa= z%cN07P_cH63X;T$j;N1Ww#d6kD~m5d5sOqjb|qvJvKsVss3v($#SfB~G_h83eMGWy zrg9QvW|KXj6xA{jC72spszXBjqwCnNxJW%iDs`Vz_hrY2s=ZIM-Q7WP$GM9~j;L{p zQZGIIwEF1jCr&@~kf(ZUm-p$+mO%23EX$nH&I1uJv?Gnel3PF!Pf5xIlseo6N-HwS ztiuJ`@Wv;rIR^i3#mR0mKLyfn&4GlgSsgD8v(Gep=k5KCawaX#}A4X z)nptb@RKb-zJlV(PUZ!v!h0@;>H=;F#u2UkW2zka20b1iCiKs&tR$9OPhM| z8S6;NK1-pEoMeR-|~lLW8OfFs&YW1V`=N$X&-JuHdP6Ep=KfW)buc-vk3G43lQKYUN%F)%Zo-fqf+(O!8R^u+Sru~bUl zJ3lXL$e}nV8l9G>*Q`y~44UlBr?IwEMMofIOSG)wowpY6K2;tP@vT>|eo@9RT{e0= z*%&0s2<)SaH1T#R(-!6%nO#yPf5S-BqibVn+(WP-XSl6~^fRNFAd1IjK9`6|LQXbE zWpiBR?TOwfOmso?C@pGae)@CBfFwFzBy(>-cVtyR*y>iny3t=@-u*sqPc_`D4iY)D z&)%hQHr9D@-%>=qs@wLkGQ3L8te#`6j=q|DFb=uH_kp5?PfC%bU zt-XF02308|F3>@=P7l}_RWecb(6Cd(-Aoo;R<#_3CsW1-O2bCegUr8&EK;!PmFe;% zQbokDlM*)ML@jL{G=${7{v7NdhK~w1e{5nFoSqH0fk{n9|9IkV8zOEX+=9lTP9`?vFTps ziwB1-&^uaG6cT)HlHzZuEUF@z-o>quVGEE(&*rN&4O+Ei6(U6!pd!;eCmA2MIE_Ci zu^AhhIS5r-!`7{Lh_xY48XWGaz}8ezUkIkPk3dl&;;k8%{@2Yu+gR_N#3TGE5{p*2Y9nB>dgAEOsy{#tFif?(RN7tLyu5IXwYM$8K=if7h9cj5 z0L`3~OY>U+c5vfOZBZq34w-rhVD&}|G_6-@GSfxG zp_n-|Y=hp3f+UL$t7%bEcdx|h!pkHxVxGLs0m1L#2Ku=8F;CQG2t}+QAqzyX2xLTw zf7IYr=3mjgsv@MkEE~i7rkR;hSY zcRHCInir}0c}j%+BiTW@zfo(Zy-d8U%pRE^Y?K^dW^1mPHRl7Pf$-jIW*7c>9}Jt zqUrX3)b)BU(!eWE<><;FL{5Yhe83%-|6B}d{J*Z(Us9`l&p%C(Xp(L>>2t{DHI@Y$ zgW}$nRxH|IP=ABvUp!bjpTwHhA>!4yZ){gJIX73>lt>hYCMU` zyt63A@>x``Rc(+bO=#IIJEg$!pwZu3*4J=n)&pzXj*VtL8aVgKyN{4ul1P$;l$NDefmQ@us z(a$j0cyu*R60nG@o+Gv^R^B<26$CpX>BFMcC8&tjMpU40D$CrPs%<5g*N zq*oY;)j!;eM2+2;D>Uxa14)`}I${YVNPcwE|7-XWxUw-&mW>&3nq;j@(O6!R@EOmIS435c zYOKKvg6c|ozpgSQc4ms!c|5KG`ad9*O_>g0Xi;=L1zL{lLpp9oobN_6feW3fi>xJ^ zN!cta=V$YL@5X!*_Lm{rK$0mbf&sYx7*?1NmL#%iauUagg0eu;zp_Y>gY`+0XYzjp zc_ueCS6&vT%Y7pw8!F?K-d=YWOoQ%jcgxOgJ1NQ)GMh7VbFP|@66y4yJ9wiKu`BB& zuTf*C$aAY|b*!0wX({Lczdlj_C@FI?jahke(Cgo;X|kfGH*40J{-8!teONIUcIx&U zBv22Y_{wc+*oW*K@O@^=2##DL6~FuDQa%l-o10< zn>Wu5kB!Z39~$!K{B@SFZot9i*%YqBtk#%SS}XBsGcYvEZyizwp2jZ)r~|`Tr=Hi0 zZ)0XXHi+LAhDbJrE1dSpix)5A11=KBrwg3^o4=3JD0v50lvhNI++4HyiS^<_gYJ#he!(&72H||F`e}UGSkPZ5G&_cVgGPi z*h}&uiK>89!E@3ZeKK}z_61#fq*UtZ?tV^_8BUTk>o;_r(_YhL?sF{UUklX4Us7a_ z6!~PR#I?V~WApFgHdCf%aa$RkPMILLgF@Q}Dqo|%MOssi+Fq$_r*e!`?j33r%3E>+ zY_2@DI?%Ejz|AsDOKDdc{xu^FXQ0-wgLUtq0%Bv>A*cE1wg(uX&ICEWtE?I`bhXYDcwHr?{8W@jUet2Ugl7N- zDDrUas0nT7m8mbp9WMHBOaUqEgceOXtc)0l1U~XWvDmQL;z7Onx2PnQ$8zT+$ulxl z9T~B@CJI}&SgCB*if9^5TgM-GV9{D!(=~pe9al4w>nKMuKpauqmI%l5o!JoW&N$U# zX;~H_qNN0$YWR@G_}pgVcZ5@b#$y~$GoYr>7ROfwP1cTWmGmh^iajdp{i?x}Y-ETt zeH}P-S01D@G^@wiJQ)j*&Mb&~XLgCb zGZk@cX2w@U(YJKnFVS=);%6z!fB5<5Py44=3aNF|oVI3ngD$+H;6Z2pv8E!pRIJD2 zmKX92rbOE%e7x0Cug&|xPObCPnmA~bfEpCf*h*3=&6qS25L6@(6x<)yX4ArXNTFkR6OhsbrsR4@9~x zt#@PcVv>F!n~e1KMv~bFSb6_^Uhb5UN#=+mGrqDN#8yy8=vp9#K3t%s*R0}vA`Af%El?HFRj5? zx5;7tJ3|GKuOlpw(4(GLE7x5UT0=1vM)2S)8Lnh_SmS@04?NZtsVfpmx$b@q_bqIZ zx)DgS04Ec5RY;e-w8H2GImngVkS%|WN2)TGEBmMgYLPllotqw(%H>oni`cGe_4uL1 z#r+GjlaqV+F(200 zMNSt?+EKK!l4}I$F4k(22KLaL3R#|oU{60j_(jFqJC6)bQ=q(izNZHtbgZv$I!dDT zbcAGnTw@i60sP1`Kf9UVv5R*$D#9oSxkO6Th^HaTJ17Y5vqY0KXs<8Hah%CfbP%gV zavnvgKH?>qbkaRo0p%b}m#fvZj8NLtv~;diN_U#?YiUN_@X(rZK6X31`-+gC2SGn> zHv37vge@f1-7Zpttxi-Sm+zB|T|JUEJEG{(VjQA=60C`olEnW~d8}Iz`hPxxrG#wu zN=AQBqeyDTE|L3~5A5ml)AhLlY!-3@_>Knf-3(~5Jb>?Hz%k8%69*0qEFM2TFtK^_ z#*G8>!!yI<>K4U=rIcr~=-l`fF&oA=hf^U_*rK$^)=cyEQ;jQjCpxTghytv<;< z-i6=hfYTLZzvt_Uv9~Jevy-y%A>2VLczl~zt)O7d5JFJrbq;+HsOQN*_OPHme|~O0;F#kCs3#7mv%m6or+Dnrvo@-I;7wRz;pq%E^@h?JM$_x9ZL= zUw>K=apE*>l3Y{RJ=)zbz-diFZ{R^(6J_BPuk%3rJn2@It<}@r-QB&_>O-DQqJjlz z;6wN$lf13+xyOBh`y{4fv05&->i7I*uwLXetB*WLw8buZ?8w1lDjpx((APIRJ2o*g zI5`2sSP*RDz$%$|C!M5+UA9h%GlHbb>n3ZaHq65kG@?C?3T zw&6h#-%#LO%UZOCoPr_&Q!_}YoM5O9RO1eaoW*Ux#9|!pJ)@fAywVf66K<;`JYa%q zoW-1yS(>IjD2!l7n{(G>yd?SlecVS$gzAT>7s%Z8Df^#%gaW&E*;^>e zt{*sHpIcnKbjglt8pqjZ9y)&fS^L=)%X4d}J8g@VxNdPI<`>J{WlIDkpLKKgrMS%V zi|;I6zibwfOoDOVtv`~{vVe91L1cKWa~A-Mpv4Q=kmE#U8eooQld`Ufv~JNR$7cma zK%#A6&NC6WwV1iJ+Q>s43iQRz-xwVe8Tngk8EKmwMscXqv z_CT$6!d8%g#k(lV3N6bt%ORcB{-rgB^(_-$J2o1uvLrIHpfIu`NCty6MP~$=&1-@v zeuySMq7Ss5tz<|EQQ;cTb~|6IB_+lzjOUJ7CJ!Z6jA~TFpNYgw{uUL(R)9B+vN|gM`cM|uotV)g}9uAjw{Fq zL6x28 zP^~5CSbZRx_DMa5`H^^M3~#I6#u$-l{hp5o27Fc!d~9_2U1L}Y^mArHOO#4O{?LjH zr^Y(9Kw1+9t@?BwsjHV~C~-PuU8C&APL|$=)q(xAAk&V@cPYFp%Ic`*T$IEuydePX z5hCm^r_)9JFPq(O=%lg|R*O}R7a}p0(RIy{9ZBX-DTd(cyz&7jsB^+o=-OWeww#J3 z9`PF)!Mf~2WJUO)`tkWfJ!8e{-h6Fns9v90n4h1~ENf=;@ZlM1W~Eg(wpL~5&Y98` zrd_eavMaWIa@uK(`ISy7L3*2DH#tWzVt&aM5*3Xp8i{T?lFe_D^+`oipv98f>Nc_P zunq*oQHR&fsA@h=Qj5jDH6>_B z60I_wE2j85Crz96pohrXRkI>OV@wX7ZlD&AtWo;CWAm9RR$K~-Imx9XK;uko7Jyoo z&SasaNYhb)C!$TC>FE)Wo+c~#-BAUQ#Db*abixz0zS=H1@DFD*5|lYRu_+p(MN*g5 zF(BCw_@vH}MI49{CW*DAq4e=FSLCM@Yh+qxXely1I=jh$?$l;Wd z%RuA{j5(qTg2L8xR`eyqM~})fHcnNo+mdAv;YUVB{)NuU_)@W~CySFez+JB60mx%jo{#xx+hvV z_{q=zlPw|9THA^d%rj)xu@Yxvc5+gB2^P6?f)n67B{ADRnjh+Y)uw##J z#owhs^)4VkT`H?0O`-mmV~OW-hkJkE-#5WN zUr5E@*SuCz8tzItX5Si)TID)OE6bwKbBDDlc*qwp0>fRHj3#y8 zPInxSoaG1Qq$eIx)YEr)I`h5_ic8|X&h=FM6+yoh2f0(fWaCp0+3c)m?n@X9mo{^r z<P$`JRNhfe*u>unP1of1oT+91&KI@pgrvaDruqmc2be5=2!CD*0q z{qjw4{`ZyVud*Zwgwqegp(|GTtpk^g*^f48jsX#j`G9=N&CGzZDzi3b(R9B&VOehb zaqa@$L3%Es;{9fZ6ylH$#lNdm|>_E|C z{o3`4!Cxe}W0iJ(hB(Nm?z@tk>Mv^^?;3j}>6e}x`P2;Db^Ntrl8AI_^m*qZyt;oo zU)W-kE!#^zUoM~qa*t_tCh8~ot0?Sm)PJVEdRIC_w!d{=W-R)gAo`-$_|C`6oTx(I z(Tt9<5?}C}>$eu$nC&hrB>JL`mY%BZ1rL3zZb7SWvx45u&Lr<$RA7-sWZLDEbT4h# zHvKo~rn;|DSnAf7k)CJ7bGj0S2S#Lv-JOijELSG^+@#~nuOZva0c$8(-@gGV)tzoR z+k}5t+9mLwPeq;r1uw~pyljP1B?&JBr1w_+d**iu01B-SMDs62QB0p+_@8UY@=xi% zJQQ=w@hB;cF&#K1BtzGDMeGZ-YTpjDgI_t9L^$ob=&F3Jb4?M}Fz_&tq!?@QhHl|7 zjl7{K5)|Jf=zlK=3wNibpUetyx-TNM+4XYmlyW*hQ*(~H=DE7K+)=RJ+U_E1^Qq0N zJKNflFJngR&&5&yMjnCnx!DpazM4B%-W+5HSp-R6od8F!+!!fbQCn=9%BiCot;o9! ze*ycq37XG4RJOzKKK?pKaQ*k>CP}pG)5V>k-gkXULG;pwaOe;K+?p^j(ghm%6}@|H zKl?Sr6V0&byc_Y;Br+%r=LbV?o5j-}#-Fa0K7~pBNqzeR8qgr|5H5Tx)G#5GP$Nt3 zY45oL+Cf(TiPD}zzwwUHY~WoQq4>WcR9;Y*AhHcm;OS^eQn|Wc0htbIIKtxTN)Y~j z5&3!mjeI%u!8f`EQrLB4)sxsitoMYo+ne|;Xu`y(oAx?hKdQJU%#C-DR4>Tf$p{l% z3~hDJ(b)#|s7M$TWaiDfJ@n)VncO#e{F^ef)e1C5xUX`BWLkK>p8`bMUsT##H4NQ3 zkut4--08xn(r^$W*hO`UTRfr>Ss4V&zq1B;1sk_{6lpvPiC|JlMf)LVXaG4oUED@V zeABN%*g?=9g@J0hMWj{ET~VTQ8HeS~&qfj5TzyiPbBc3xk49;Qual0O}Y z=Ykm7<#lx=+}jvn=JhquEyxzUq~8l}<#pao;|X*I@9&oLY_~qvU5Dt8kJR^$?!wR|F-2(>l+ z#+xY0*=>xU4i*E;>akBQJm?p#bETafx5cCEz8eptthA%n>EpF~S4l1r-YWa)Y`nu6 z6J8KjmmB@H5v{K-j^Ov`s4Xw#Apc7514i;I*zBDbkr6^53dy^3G#ZdpsKgl7SeF!+ zr2U!}S?I%*HrF}pDXqx`G>U#3Ce&_c^#ne4{pDA+y@v+HPF$hdH!I1QD|CWADSu{WjFdPhS%5dxR6w zHH^rkd_r@RG=RTORCv0+g(BT^BoLLo_P@vZjGZFi77_8~8zk;~l-yKlZD$_z3kQ1& zKE)Wfiimg~qU<{@kBC0+B7+i1gZ2Qd{srC(Pe=0pH;WrXD(&RjyT)70-X>ZBxiXa|Ij6JBYbFvCh8XsKj%(n2ZFLm}M24+qSn& zd0ZTqGc+LvA+o`NJrZ8T+z598;MO)J4Tk%HBc6-Z8F%|e&G47JDTf*}Q59ksUpM^_ z)?nGp4Th$?XS)VwHie$pmaju~Sy>xg+uO^Vk;JbV36~E*gagO)hn65*C&Wc8!Ie!J z;tdS$@$T8p-})QABljo7D}`PLiQ6v1|HnaRE^BFvLFe7(;Vr7DD|LYRYwlKKtl&H+ z?sRUq>+?S5u?hgy?$p=VI0(CE}`m4Ub5+B zw{L=WCOhEm;BaIfcc$8{!PfV7?KUwtXy4>)LNjw+!mx-%ZALA<{C06*k#Z5c6A0Io zvo3jAVp%S23;W?0*)En-tPGf80Tkx-%H}!-Hb#PLH3INHKLv3$kJ;IDC=>UNh$igh z4ex9w&fKzXf3_by76=EoD+))5(po8LNIv;{*d_@?Kjs!q@2ZfZCio!*d7`_4muun- z1}xuBea_V0d?CPB{@48cH|4wj2S$1QI&Sa)h>r`Vk14Kgm1%eC))wi`cdm~-gAunU za48661p@1^l}-aLiwnoPW1n)e!Av4A2!XUZ&NO^i>dqrG(01kNw>j+Ejx?4>E>e9nbwOjR2 zjzZs#)wLH~V&&JK(dS&7567l=K}O)N|Fu*e@{>D3PwiBrRhE~0f=E2@=ybO{PcP;1 zKoB>ynnR=;5v;O4Qch#MEZ_$qa7=Geuo7Lc7d_ow6T$x1eEU_FfZ3~B(E9!5>^$?t z8uCDy;L(-(sY~H2uL{hu)8;vT=keO^G%HNNzOMuDph4S%$D0K=3mD&FYcCoPZpZ2@ z4Xbnzo?7-9O~$=OU$HAZfOqKEpQ+~atBlHaa?SWh>e^Kbq0F0mN%?h#RSn>+c|PPN ztBROAbn~Et70cq-+Rs|T6+UEhTQ0xS-|v~;#F>-8ajf<9@5MLC?OjH`@qQ6G)(Nl)?~ zQ11vb%C*Fu9Z3ai#)T8NT=@n$~sX)C*Rzta-*fwfkrd znj%#&yp>I<5&c#5G%#lOq3XI$s%UU)C#>_HJFeC9UG6pFgjSN z-7Q>MW$aDdEu<{WoXjm)6)haC+^xwtctu1I{zp&m^~*l?uV20(LHs?byyOjo+l2hW zMh-2IcMbdh!sq#e$O@_d+LluL@EdKoGcq{H?`i7C6 z&b#Fajt6>M-w3UOVI=go0}rl4B%dUW{fP1%oWgHoWp}@Ppx&j|f#Fw4g}FHia)69Z2jKHmf1oG*S{!d?k_&Yj0s!-;YstndQ)oL~1Oji205UIoz# zz}^?r10xr#m+wgZwfd;XJCGiMa6Ra2(cVQ9qnyn@eAYLA8Ynb3*IEA5gh1$jtei zvqb9<4KG2nf$m>V&Q(Fr(0sS9WqS@MbhZ!-*D_kL_aJoN$EU?-T;ss$gtO~wY`Zjb zLe&(fLe>EdB`NfAeZ<>;Y12W^08%TUU)~$jyS2;IH7H1OC4cG~2{rXkQu4#g&`{jJ z4XUvkN^u+zSBneLaMNP^d@%n2J#Gx*qv@i+N6)PCVx-^PyuZA)l}r8-0XHYf&?TtB z**o;-xsW^i3(g|p)%Q$&`HkvjIK$B+QEj<}n@YxF^+RogzU$I6$`HaGsUR4C{IJSB zb%_NkCuSBVwDl_{78Va+PM$tR&QLMa1pK=t6|Y7Dr_jG%Ygg^dDn19O#8Gd5;zk8Z z5i4My(bIU5fxOcnBJAcyA7N#-k5hj6Mic9#io%Faz>dTYj8O!gw1sArm(?xex!^68 z(yNxyckAN!L|i1m%C03IbmCB-nGSseh;Tt2N7%M^pz!&bSVO}~QK_#{X_4>4>!fxz zr3|5KHIz05iv%$~^w>RXS$>busJT0(lEZ&H_|YueVT9VuFEYO~$gll<>^r|reE3HZ zUV{8Wx2OP)79*+y48zmIqbitom-w=Pl)kQF>sYlz(sy&>=0P50IN;{e?8fKJk4(UF zAKiFGS8oq~LuXmhrj;qz*gjJ@=3a;;Z;s1Uv2NyJH`v49#J~Wqoz1R|>3JMqp^u!6 zXA6A@-?5(D(nU2t_zC6!9kmotc~)W0lGDM%f3qWjolazx7EwYmIK)qEfN>hL!Ty^{NA{+lEal+3l^es->>2t>_L-w zzBB{XSU$?xi5lDnj$x20k|!O8V`tFdUbY@f`|>rujptv$}H!PLS>)K?R?pxqA7I*~Fb%a7+A zlu-=nwP!ZXm8O3y=d!X2^lP!8jJ!byR*}8S!Q|!=u>@PJEbSE)X+i94u#z+$zu>j>b zi(&yA|76VRjfyP9NF+L-L}79U|04RjNQfbWTyMy$6p}o&shh9kJ27jzG3JIRl~@QO z;hq@P!^(-u9D#dDLu8RvvUZ#x*B1svX6mk#3<0@CZs~<~q;Ee{62Chp`5GKq%<%mB zg&9laS7WoAj`v%9yjxDgAdh6uVz2fyXy1hmeQAJBd+xdFI`luwDF8vwKgT|>7 z-b5L>kUg>z)uUeDwPJwb{s8pGa-5E<>}kfAEwJnz{y+G$p2pdCqj=5uj++ismvn_# z1{J-e6yautj~`23bZ%BA~7Wtv|<+Rf|i8KCNk<(T$XvK)(Ll(GbQ zZtX2qI47{x_z@osaMVejQUlpk{x)}u3S(i?Fzo=?_YzJ!OgITZbY^K|N=kCF#nZ^ZO4mSj+0PV|%TpLSJf{>GpFTrVd%(SIn~5DX}+l)CKMb*Eg7 zC2WRPL;Lm5CW)(ErR{~2_d~Oe1xqarW&?sBGRg{%w02Z26n8&xCE)A$#V&Inj6)f z0;d~7x%Y&*&hx>m-lW6n_5tPqusia_Vxc+-v?R+h&QYi{>n9Jt`0on*W=8b`igATG zz4Kr)Bj>&ZdQn<(FFe_E>?oK^b=q@*?Shi`4`AkUAKFO@pD;q_OIqW3A#!4toEu;K z2t&wT@ny4f4!7(htb{M2I{vG^tn3yaCM7etTYIR{;EGCe$(He}&ZJ$6g>AqO(|xi! z^bbv;l(4)vf)~;s8U(XJ3tJ>q?g3UcR$9K>`D_^#{g6%SO>Y}iW+9IWL^tI#PV6;9 zPv3b%f*t*0I*O5FfipX2Y6Bp}myW!f0%I1RmIFP!!#2)JiApF^eA1|H_h8u_sXQ1G zkJ*D5B3nl4lh+ap66P;isZ$?2GQN;PrzU3yD_+}B+T%f(&BE!yIy}o;`*noVm;c_m zP&aaRaaNpNFpV-5s}UXcow{2SgkL4cw}N{>i9wJrr*dU|j_&*d;f^q|g?zK=d5%I2 zv#1Pdv8REw{LFY4O0jnPmZs~Ty2Q!xZTVT?@yb`nf*(iG7 zSl*~?4|K!4-|sxt9zruR9aJV;4>Qm=Dx6$3l1{@|15Oq65BXLF&p!iu9EUJnm7h?O z3(?t`aijjI)f#;Myuj%Ewd5BZp{5RoV{B5=ZP?$v*Nvhq&y6!NBM|o;)@mdFzv$*% z`?>Wl?P`Q{t*my8hSu4oZBG+BxOc%5f*evdWAa>br-MnC7dY}pVeDK;>R zY`kOALpPySU6S1ZUK5+u5o%b=&iril#?6b$6V4RPaxWpT!K7iG(&+3&T4l?%k!AfG z*zE~Jn5X#ls0rU9qGQ4gakJc+FPuj(M} z#EE!)jQPrd>x}vscjR2}`^EYO=C9uj>2fwjiWXzl)fm{Phv3r4>$9;u0KnRUpa`O> zuXB%U(lGpBcL*)I5xA)|Vtgcr#u^F_&5oCHi8ETlHe;N{kbfOmYP3~j7za=uEY)*^ zJ>3V21pG%n(=Oaxa!32{rJFc^amYOaah>d%Ota$0|KUJ%WE~1zaBt0#+wVo*Nozv- z_^};Deku0JVArX?wB0HyyLK`b-wA%Bp?kYt6F$$moBG$_9ME^(Vq2H9RYO177rga` z_=fYForUcD1#%{lBFGLekx78;BQ4uiBFf9}liUWazPLQ-I{EdNswJ9?R3E84x>8Qd z@72A7lD*{osC?8jbe`6~MF!+?9E!cjncUc;hD+9p_wQtpBF``{R?)PM;W$XE^(hDe z=U}eLKogI`BNdjr4db!{(i`yf`_;8CM7eG=(iu?{8$Z0!#uA2hf$O#tUCSah28!&LcO{z z^=7LnN~fy)nSJ6cy9#Bj(P4C`%mkK$FoBv0V92L~k=QxxdEO9n8RzAhlg!j_zG}QTAJY~S_ zWe^NMLw@6In<4#K(U?CtAP2_=mleti(T6C<_|VPo`E5+%9v_f=z+++tv1Z|K%)}OW z4k=#^(*6co;QP6crT*sdPtWDjGG$ z?OX{9D_s;S3vbw>gw%5XNRIsg!TfTATgJ$Is2J%Va?O865zPx2*bz2~LM~0QkkU=% z0W_2xv{jkv6{bYkR^@-z#2e9K9O>*&Ohr2>1M=z?kzIcd7=|^rrj}K;m01M+uv0Yz z4nNTilOl53Vs4Ly(y`0K=xVN{>=HVw^PI?fUaotXoXGZlK>7D;wwp-ev9cU#MD~o@ zf33<5ZBHBm;n}bAxU@O|gZ(GnX8z;|+j%~Gf_k|!cj=CQa583c^fp35dBTJb6 zZA#yVZYzh6Q$p2<-uWb)|9}_mXDbb{Ys&0QO@6kE+;bNtT48Dg-GC+3T^&kZe10L< z%7I%KWR|eb6aTekKMhN))$D=eNg3NNJ3!_jpTz}?ZXguz87=EJ)CPUt`3 zZXy~EXQ%Pw_e|)C{}j^iiZzx#)J`2_>SFpuLjC$UvjLPgU>28LYLoBzp-%RFAU)-> zb3t#!u#TBJiV*6r2Z6_m`{(RGeJ7b!#9YEEt%1Gz3D zsK+~psP>*h<>M~idlm-MWk{Ki6b`$%L_@4i053 zzf`s&PbWh0E8tm{JET!Ve~j*s4=O=q{Uo&BO_|yxYF12aKu_%0zv(?R%2Mb+4k;tn z?Pd8SUyAWLL0rJCzZSnn8fogJa2_Hr9$rJ319Uhx#y86szo|ISPLYJu_kYrEHh)6>2q&(FUak5RSxQshp|YY=WVlm5I|({5?@ z=%(yQ%#j1nILS)gRvquQpTbkn%0`P$;|@mX_IC2*$0pCkWHv?!EBVmQPfjfY6(qB` zKm9!TE-UM3YF#T<-Kipwd)Q(%y^$j>BW!*8zwI|(E@`MBKtm>2QXUgGfArs%W^WGm zHbcLJ@8s@%DTP3?Si_`GZIq<|Gl)jpPf(#ZTi6pGuQig@`#?z;M)Ze6+Yr@z{_f=` zZ0?$?r|N)D7|0tz286YZM-`Z6ziL>^#CI?u3v6Mg8Wh9d(#8#AbMU3WP%0$dg%kd@ z&<~}8Z??zQVl~n^Y_0!HMQBk%#~P7l%{8+hTZ8yBjtm8Yni>%AQs?(813kR%_dp-^ zZ`zSxKalUZAzyE`qP;{QUp!G(^C(Z~?w%x1tYBr}Q!v%7v?}{HBd1d^hkIZ7%QCz4 z9=4_J|Jh;{3L?qKsf;Pd39tLq`>>KPY`VpqgBlo_lAT+KHWEZ3@(Yn2VGB?-t_L14 zK#(KN*>rkVjTv<~=+n1+^}Se?CLr_~4aj3pmT(D!w{J#R#mG;KoCb11Rp2n888YT2Gks+Hg2 zxpTp`AwWX}@<{!oF1dpIEm#=h({Ai8y^5Gy+=?Vys8t}?RnTO}cahtkM6oVcLq99&Yjx%tGexvfBtTVI{v zz|vM5Ie3>cuIqI*%bsEQe7~pyYr4qMHMcA^Aubp_y)3=SN`R2up*>!>xVi481C)pb zz0{&UAFZM~kCWge&Ehjz2JB@UeH>u-n~$$UjPA40wE(Y_*l-1zg2hwzo?Bmi-*4Yn zY8zd%D#5Z7gav;ugodQ_y^#E=f}~X)zewo5sB%}~p4qOErB)XwB=Y=;{DLzJYv;-( z7LK1Ee=cs~BwMauZBC9khoO^7BkbPM;eJFAGar&q5F+cR5@_*gd2Zcs)zFyy@y8?J zGKi=ZZV;bDVFB8CRgj-(i*O*w5{}0Pzw6w;u)IJG9>-d1cwLl>UaV&sTqS-fvvI)o zs{RvcfFBl-HYpn*5101(mbX1kH2O~<_~*b(}+6a8VU!qmNPfOG{V*-ImRt-;55drsXryf0WCxM=qH7=HwSVe_{C+?3V?>f6fR?H<7Ki|{ z-?4ndDBWj^E9J3DN|};LA-2)6!uUp^u#kKhfjDMB^X9%GHTKx(#Z!a_!4hBjR0Y7u zOH9nI%+dAY9jqTSuNAc(D6}ZQ|MSo~Pv&nBSF@^J9v1 zSRX1pRDT*&$fm23(n-VLXTy!klm?+PA{D2scTQf3-oX*I8po7uII$R2|`1gfcYZ$408n zK$78}c#w}3O(34Td51)Gvdi>!ziH<+ng4uQgN&t#n1N$E$F7X2RI#tH+}XW)xEbUx zL)mdl3krputuL8n+FFq+XwZaj!qN0+CkCUUq!P6Gq}|B#I1bRmAeH<<&rN!<%zQg9Z$ z`{c5&H&02LXtWAJy()F-MAnFM5IHmq>ZLjnJqoLEB%{Q8nl*ff?LJzuP!SWuqERK` zU{2fc?z1pS^*ug-Hv?HCD{rz_9jz8Q6cN!@AAPIlfsboJ5A%QM_&Z|Pce|Bn6cgBP zMVziQ*$|%1hp>WMYBisO`KN}Y@gIYtfd$V`gSx!44{oDgZ!Qn%UoRffp*JSG3%X;T z43t#zVPp#N_;JP$mZ%2B^!RG*8p+4y=;31D(r8+nB`x(X+LH-%ZG*u#hS7iD%h0>c zce(>=E47Oe>nRh=5F6IfGc<{nFDIiUlbTW)U1dF`V>(WaXdj6&CSiI9neHr9k?3@B zQ1R-WLMnwvKt+Id)$kwwI#}Y0+f#zx$*;mO^40_nUlhV|8vAU}bF;vy6yd{!gh#`lgQn%$$5uo<48n|k+L*79qd z@s5#)9jka5$W3bKv;aq~6XhCCiv@#&$2w&?Q4W&Vzhs%5%yI~7bIbb(X*48eK=w(L z5`O1ny$_Y_lOb)PfdLx7m{EU-O)kJdpD|PNnY;z40!b40$!tL;{jCdCKgKZ92{wz% znIzXCLYtsWZmfr;x=a>+NpG!MI2Zw#sv6{fg)<aYFx?Y zL;f3j9nWxhrdeE;5;|=IH^ZVMVLxo7@Xd&Z#u9(}nzG+~J&)96jPS4}<#1?H!`1h^ z+F&Pd45h!Ey{s3~uju1HPXr8;S<-fJv`E!LlzUX+=<_GYfu^*6z9AR2cF*=lSv7z# zuNwuFJD!IYgwe~1em2e|UhP}G-#$`~nQTQ+0U!ta!4>GZo|zUXbMWS#Ud*pn2nJo3 zDs}l7VGdX!Kju;9Vv%GXms%B#i`4|Xeap#!k^65Rt1USyn07Pmrx%?#zQsY+W}<09zdqpa+_xx z^(q71QOV77=8Up4)52FI{S}1I871@EhLauSi4EIF({m+(r!HhV8mytt#uy2U1{ji1 z+A7`yL{N~kl9J$~#jPpp;ke7n{)|`Bt0WJq509s7*4eni`sLfWs6E7^AzJ?NVuS1C z^H-aQfC__|9WAL<{|2X4MxWo zpdlhB__{^dzVB+F83J|ec7JONcBBMsx%O0tZ(nv#21n>lTfG3fyVME;Tc6g%B2Cp5 ztu`wX+OMn!TpOCE>!Kl?7V#*532?xSJxpuFvQ^@_*=bL8bjd)UHjhBUmd;ZYFBub^ z=dD-@0yzq&_(u<;t`yFhLk8D6v2DB1?)dGVY>DT`_(Lygn32q{!}X-0$th1shm5hq ziy0*PBDFN+E4#$HMM>j7`LiuILBfbc71x+%7&p_Gtpv-Apkk8gKAP)E_L|=2-R62_ zF_`;kaw;yE)jfGjQTxGF#Cc}{XSrUc`iMwsc{gKoG^uD`f5Z7x@6T*PZ!hJUKlb9QRp_=#4Pu%DjZ|bH_vQ6(E2KUY>vPu~h4!<)h zB>c2+r@vGIGU=->*t`7&c1Dzym% zf(lKb$fM2u2AiYp(6ZV+sdD8u{xrT>bSYPTCyB* z+~&?jF_(JQIoN9Hlab2&*nqIkHVseNj4>$WUF*mq!< zP$DV}5}UzATm7-`30 z^4C4yTX#`jU)VOMW%ChY?~lsr&V~zLyigD`M^B51k z2K(|gk-{i3Z0@L%ebEb?646F>XhiBb7h#fC%lPq(Jj_Q}TA~5yhCged82=t&#pZi1 z5i?Q_>(%PREc-R9(6QE5>kF^$7;Cl^b-t<3xm3K)!y1ezKmnK#87&-n&;S0z8RJ-} zX_HyDF2YHSDuLK=mpuzPU5?@~SvTr3kM^fB7!1cqR&pK%oHo&~MT0zkyUfAFN(ePi zc;Ps-KdYar&$vZn^FU-hxlZz4_-=8Nv&J{{>cmtJxqUN+3U|$3tC?X=@eOyKzz$4X zjr-(QU@zD3^u`k?$w)P<9cYsk;9|h#FB|{*@ipM<5*eZ@zVcqz$yt%*ke&r&p$y^= z{PyJQhKcsE&UUGM@>59qVG<3|U)HOe)i?Hr6XwOI2?29}dEW*@Q+s20Yi$E=j(kr10Mq$?K^{>FvRy`J$3`y};Zx z{gj=hxvQtah44hTXR)VM!?^)#>bG!71_A+1h85gUdgV z*tbWXW^bODqLCo8f>f&K8BNBtGe)D2oAe%2^6$F3-aqzks64435X)F8dokWZH)+!n zlSHgtRNvBys^DByrw-E${?-u7$AV5-|8jhX1r7O}m?qus<1*`s9xyN|?UcP#>=U8|DPnARp6GMe?Q|GnG%;+VP>@%K93$*UV)kPK zzE&5Rc$=&x-sr9L)zmh`oBt}S$C!>JhBe3>*yc^6^@yhGJMwM1QGAf1_M@XmU845L zAT_-}_zKb4Ej^i+S?=DoIZCj@QM#|)<$n}iPt$vJP1k(WYy%-GRgWWGEw0m}!moQ^ z{r=ps%*i5yj~B*35puX!9H_ZNcw}EqKw@Z%jC6t9v#5*nsF3lD;4DJS9l4=LIiOmj zhYJ;WT`@?8l8-b`vXIPO=e1GbT*^D|Tve1En#j(5OC4bi(Cra?@yjFEamV`svZeCZGyfthRCA>T!1j#wI`59Bjd&_5 za?Xkx0ChP2Zna{1LKn^0YlAQOkDGsBKdkLJuDiUaxP~*hQR{o-?u7UospAXol+MmC zIGKK=p#4^G@>>f-vM(Yi*O&}F!0woy;zeBEP>X5<_}CLlY4&Pk(_**dto_iHK3H8Q z-vOTKdA|YYL<(k4(7sa5Zo9)w zpUhrZ^{P*e`*dq~4Y^cM+xz+eQy`Y5qcUbW^KX$C92Zh=UIMt`a*2nv--$x-!wK~1 z<$#w@Z!Zo`{@eHKml#hNgMWbm!*YC$ZA%E#)~|(HY*}W3 zLvG9>Oj#BZH{S(lRGoxCmAfsu-+$L~D!&EHbHeGNXDx^eE^;n|4JAI%q|-Q~eMI0k zs?SP;n>}Ry6zy?;T_yFcEI{gHk14yIOQnb2O>SY7>tsXq@{7^5)5`kVB$|1AY_+EQ zt8=cgEKh<*H!kESt>#kgZHqr_+ZO3z(8*?OcVTl-BbZt+5&R135gSQ<;e~^`lTBZ= z7;<`M7x)0yd38S8ePH+NzPEo*p;5{Vyy2?S`+Le&xNNiO3B;cn1>Uw>6%3+f7UCz{VG*b@W`%|TR;p`j;J?&2|d~^=cNSL)-M;Gj+C5YPa!C=p4hik2+IA( z4z8|mWBkzDuloe>ZYr@K3*QS)HH%N6Eg=sOm5o#`H4kNEedgJ?47fHC-IgOS=ynLQgR&MKG*m`T>2l(|1#)P$QAwdX%bh!PSHqUp5WD~ zUi5K_{Cea6to~o^+?Q)U2Y`z#{h!wVcWuc+_#J`FC+2%y5%}JB3cQeZ$NI$mKO5!h z&!6}FuPz^M^2T-CD}^?qeC1#hibea`JIeX;Csv8`jChUM#h&j(HrCeGLa2Y1X8ES- z09?aqGttK1BND;APb;J_-V2B*EpOkR-j9)Xgt1MsOY=cQfLHHW)a55sE}!q%XdICE?M{A{Cto< z`I`1F=YMPX@9hlkeAK56-A?}6fGAndLxwlw_+!*(1)~FRMaloG02ZZev_H=PMuKU% zKfC;&MHw}fb$NDn_K6(i8GnqK*2tC1+bR7&y93&!xaU4=|EoNyfCyPN7kO;ndY_~& zG4H=g0%Qj_l*Rp30Gbj2({S|lSEz1+YRR8JP^bQKtMUbJhqeEM2|~<()2HD`3J%a} z&L`^4Wk}iguBKbqfAUtdl=hKS^W5#$$v5och&&fvVk8`u4BBSQf*h$1X^59UVeI0- z=Tn}GKiToMu<1tGQB8do6E@U>JwKP$Ln3ojvw{9 z*!}ICB&ACU0bm(A_H@yqUWX$u8Y2>qJ$46b6Ba%`SHQf|8S=A^?D^-+yyti2jX zkM|1Vy$baAHr0|Ejti)*28hqDAWuT~tJ<$>_D{VA);j(=j(ln9CW=EYtLNt=O{dMdW^ONuNa=Zj^$(>4IBp+ zZvw%3DkC{&Lm%X=vM$~gyE-j-9l)ILfip48t!*beeuyH(;lR@4wXUw;6_uzGc31S~ zyR!>7Mq6(BY6MZ|E4|us6Uf5dLR$+R9#1Ad9XEH96Z0!+cO9|08bqh#poONt;D?m+ zCLb{vO@(%cwhr%|`p_)cpT}MszHkYf`v2an^T}su{9v`^mi7va6CS!ds?UA{L%Pg{ zyc)|KdU#)F)O5CCbcC|vlyR4L6O3l6gt}_Uc^_M=4rG@eBSROqx((~yVG-c3fMDzk zomA*8l;f*#f{GW?R$K6P zKvW`eCm`43^+p)D-uN)=J+n@Emm5*ZviYjBLfW;LpJnOj8hF|t>$vf_6{d3aey;~$ z&fDn#>Rl|R{Qy4nzj}slUIoH*a9O8mZ*c$X3Y8=Zt|lJ&`XI(KT)(q{a1D9ful?{K zyvpj4*z>pvLIlBHgI3;%Dti2`-eOsU9wqM?MS{opWp^u^0FbNd)Cy@A1@6=Ls_GrX zH#Pa5N=n$ z#>vrL^HXM%{Qrqc=jP$y`agrxi}m1jF^`vX(SC_bYYyw?)N{^#KmX~sq+Pk&?bNE3 z%3T#AhJ%I<=l6>h{bT>E{?&|eB?v<9leiL>jZgo(tmYrQsKIvo72mIg5uKS1W z<7dp=@Z*W}47Y8!X}|4T>EN{uGl-C0pTmm#pQ^w*`V`ulbZF~?ZTXEeQ%Al>7Uv>< z0s!7u+9tqfpnCFy^}oXF;KG1(LIFO5A~1H$_7I!+*_VxTQ5ctA7b-C6;VIvE^Yu6= zV6qPd^T&H#$g1jv;RXEzYKZRc(?-0(JC;a;MPLJ)N0NYV#l*qb0xn&DVVd~Y5Zlwm zv6ND!x~}Qp?QP%E{az#K3N*>Z)q!lHr>?lC47jJZ(pWtNRK$gFDKDcCU56j)5j~5B z&C(TWW2p=_!Rq<&I`JOK?XWQAMQR8Z(WyZ?;|Cm0X_G1y@V6=S#b;s}?qkEqSMx(Z z*_zxfl4_Y0sZ*4*>C!69Ic)xZC;pf#lCxC`j+MY?8_U}%%%lRY6=j;gZVwLGX?Lg? zwAuF+ED_?gm3dVZe;^bus+2sS{Hiqg_;Q&Qv4mhz)A7jvXtDj9-HfoHR4mjrfrBwYx1DDn>-E_# z$-F+_(rKyQ{%WQcVfoop;qdt3l|joTJA5i2Rt$pry&k(}91As1ns~S2j;s@Ct80!; zF#&8H*{VFaub;MT+sM9RZJN;QC50BPQW!&FmPtt#WD8g{cXs&J!WDh4q$g{`r>eLaxPHAyQ-aW>fa91e{8J`ukmRMx z7e;%aiO&RFwPZmL7|dDzE@Bsf%RJk&^sKef;Aw43o8Vfk$`UfTYV}QMWr9*5GLqMs zOP=u;fVUw<)S^9C7c@LU;h}cEtdDi^xPYqKKgl8gc5m13IeYU>?^@>nqwJlUL<^R+ z-L~zXZQHhO+qP}nwr$(CZFkSM-F@cWUOQraCu0AAk#$owD)Xr~-;BK5LzG`BHZ-L2 z???{jb;qPXMO`|}oHJEZ2*V;WR*`Or^XP%U7_M2-H28LtQ61=YZGYz?V1s>0Iwl3s zDdeRQk?RVkiF++$mEnRg>(6-AlsnUA0AZ%*?M$9$XDno{EbZ(zzSTQp@e2f#5ybct z4#tNCjDxQMj^kuOHXf)Ze=m8rpMucoB%7$IqN1KIiHfFLQdv_|Sy{4x^T}6zzbE)e zbTFz0)ILoZoGUt^q7r4N@9ZutEa7gXU|?#CYm-@|etmHepJ+&5oG^iDf%)!sE0`T; z1*XphS`DxWAIlf!Fc*@OWe^5ZD~6ICc-q60=xWFgzGx4lJ>^Xg0_j!@`IZb9r`c!A z%+g7wzwO)2RXR74R%eBlYYbOAlfjU71(%b`Gd9@deW&hG#T2Kffkkjs8Cw5VSX_Ms z^NK8s@=I$g9?KT$p<-7ozn5T?0D{OD9dK9`_PU~xVZzRUCwWyApxYHin%Nd|Gw-gz z1yuQ3l^%|^^N!Xy;au@TKcjk8$0x+ne6u^i=+WiRo9X;Fd#db#mSW;%WjQHY0AwY>AsAa{?E-4d| z2W<0?ggRMky1+-M$0=7E=LVZ>+17U@On?Ks{wGP0=C5YD`G3pZG&XejJx#4|F# z05C8t{9WH!?~Avo;GMfC*fa{Vk(aj{%8U!Dyj|7YthE|h`U z8GuBR-*>49p6wq2BJbEQ+Rm8U`M?tH6M+T|=Y8^d9Q}3iZI!&W@qW63bP=C?;GZ_5 zF}RE5rZX;_9dws6?8=o^uNO9?8~P^f zs4yW`%eyW3Qv8NpCvCnjqPj2)f4qY>tjCM~N>!_g_EH=R?ps5C0=B`@foCv8a3bUh7fI;|5OPpw*+M5$;ZUGwX~_nt zRz5S&w{!zu6ZFQX;OAicZRc&x4e+Ks_<#0x2R4T{rRR}(XM}!zM!BzmGbmd_Pz~`j z1P-kl#FFu7yP#C9hIR&Jlw`$A2gdY3-Oc$Vhsz0c@asHb>qXAOvc3QI_)X(q>+kLb zqz){TU(jm1;~qmFs@IJTa$PI9;=Bh{8%x?YC0V!9-v|2w)IW)Fmaw*e=d>(6%k;+> z1<(tRDC@h`AhC-SF%ErUrD#xwhGViP`B|EAQmZ?*(UvP(-@8WS7y!4Q0TsZdMjg~_ z7j*+2E$<5tDLjfS%A+@@AJ^`8oM-D$19M2G%{#(;nqP zGkd0f*XcDj7PX?c*kLqkg{3@#0D4Ip`VB!<(G+Urd3pHE8Om8-xA!xH49pF-#qXGw zbLw}fa9Jjsr;+hTfjrnqKbbv+^UN%-&jZ#GJ=&T`u)jT}J`X)OgX5P!fl`k6C^0cH z$x=CN4$?r@Z{4tl|Ks&89IX&);q-8JyF24Dyzqvyevk|(r^6~PX-qxITvaRGR_0c? zD{WTWsvfZH6ozm=31JWg%aU~IUUzbqj2_2^WhFi5ooUzzASi16q;d4g3@y{K<C5i8I_4!NqD(u4Xtd0ejO`egdf=!Kp-V}OHI9+Es zxviyLP(Y08;UBlQF1y~km=mvMLCez&AW~qwNjqCQqzquH@>aO2?&DAe^ zJ1tGpN;@1=lM##aeu5!WIAc7vtKpsftQYrm%p!V!%X5SY&| zEzBQ?P7P>62c>?^D(cdD(?CY3nkze7Ym2vopR{%crA2+)Ht&6Ox_pr0MjzBU-KuO= zfd?lKwF@M2deo$8^()q?|JmGNjPcMa{Z^>y*dI9`erzHlJ<#C2kqL|pSYOsxqo-I&(UjjYaI&hE&)X!5B-}8K2K{D zxh;%^{OEqI0>C(#j_wXQzF7KKz#F?pN=jUMiDP-(yWbXyV*atiSzqn-sDt8yyjAIe8PDBQI9_>kL%a~>=% zS+z*mCZQ6eC2VH)0pBRg5%d0}x6v#Xwz`*SG`9Cq?ngIwK5DOxZ_*otZsz6}gr+)}8B=j<uRs^x`+p82L1V*pU-n0%Zkx;V#&f|ta1s+!{-J_WBXzow z`^MsWoR8VThZK55WWS$XLGV)u=ko*_A!+WwKE}pBKzHY1|4O{!!Db&F4C+&w znd-_idR+hrW_LjFxx?b387;HZI%H+KKBvgE58gWzmYOSb^S7l88vUo3HD*89F36l} zc|yrfpF_5>C1#62O?GGyqz%Fv@hVme!(3i=&XSV}<$jiBRLDy$E!h*>7{^_WP=w;= z#IMQ{pqTNZn~xaui7A!W)zXoWOF*Z$M+q!kmsYX_REf_`%9`zW+t10KOboIaHIVH? zyLJ(TGn}jV;hL81QNCv+pR&tj3K=~7M`5>^=!Ja^%lb0cI z(*scXp7j?f^-i9UY|GYg^&JW!eoh^YpmYj#X1|#*Xd~Xl_i}ehue9vrjA_28N-5c# zl?+8bq_i4ncX&e^?5mvWF%Qkdakqa5J%^4beM|a&Wcr9$KT2J|qO7XkNeEsslOC9l zVzYL~yk0mgfr3BpkC>b&hmm{!;sb0cjH4VA`PsF*92pesM+I$qk8aq)48>2-F1 zVwkM|NuhFX=c3;2iNJO5X@s{9gk25OhX_iRf$Sk5iwT-3J)QnhT)9NC%&jh?o6$D7 zuaajVjrl%9tHjAo5q3Z4nUkpC80y`IVD%1$O{EG`cyO)P>n)$I3Qx3+H3g?-()dTX zybuU#=Y(B>c>?(hVIr_N$Gsm>8uZd!mEXsuebI9YC z9R{pbEaP1Kuo3LMS2bR%?UtqwaUH+(N_9i#$1W*y`1>CxM*&2Oikjamr;n#Ay=3kDv6uR$%;YUT4G5zJsVRJYo@d)fOLa}vG_w^O4a$> z8(U+^H`RKYYvXq~YkU#5SYMREI?UFbA*ESNh?YFi&;uilVP{=W*I)y@{ngk@&+eQd z^9F6Y31bGIlXG)xI+IL>X%hz#(@w+hFJOS-*}{K=%547wmH*!!D*xNj#7bX3o<3f# z_se%O3exMRTXPTqG#X|YfE1wT7Q*nqEyD3Xi~L{7H8TqX(|?ld5Oqj(rL|UG#6)C7 z1&&d}*j(gn5m0Q~mDbtFrjZS_Fk;3K3PJpE;3Vk@(&-=|!lZEok$7zE4}_MM8lje! z&4tbT#jVAcR^_z;nLRJAejl4_pWAx@@t0k*+m@e})xIAb$dhw%3F1V9%T>F@Fe^gS z*~|uIyi+?oO^R5=F+wxhWAcQw@JfNgt|0bBL^>ze_Uo(lF8Hm{@zPj_=;YWE@(73Y z@8?|zj6?3&ZY+-hk3gUO(nsM)Tww`v4whs^dC9+cDB|S-LaA?;Er3REXuqxwNg8wRKLinxxkz4VUTLJT-#$2f= zJttD$^w*bB&zHn2-$bexLN$U2XDkmad}8>7QQ}e23UmQesph3r7Woka4F)xb0sN^< zhxqj;S8=xYw>(*$(NgC92sdBh+}ZVq5c0Pig-Mx2K*)!Rjop0>OjC1~jxXb-9H)w} zW^fOArek#9$jdr-d-uQeX{P61N`nuYe3F68|k-f~e47C?RgR5}RJ=NxMex8S>mC|Mm^MI$q zd(j*E4t0wWcXe@{xe}peXISa1Q^mG&sR0I`4-Dp@V^yQ1Ok6Oq)gh&3Fia z>c!+LnOR{TU0GdIVNNT<=93>rRj*Ru@G4``=j}@yZMwVSSs%bUZgAuCo>_GbG;;+Z zeCF$L)ezyWJid3us7_~KqkU4Tc^=#guzVv3a~fz;tSRi~8HUo@(&_3dfXK#7dBem& zp?4i+bEh8j{@dl`SDqRs#jNWnTv@s|EA-=i%V*=P;i2Ji0r}qgQWbHgzK_cn7{Tp2 zt9&Jz1rw01w?11e?`pDNGC9P3yf7UsWk!qF)PB>1O|&t#914y}tQ-S@|nlpB2RM2D?}plQPRl!@^WUW9_B41QUe8L#IJ zVW~r_VGfFVj2ZVa2VFWe0~UYoNSjwQaGgY4ABg@C1LJ7k>EFmfe?+-3gY~q_oI2m_ zt&>``vnhRO=>P+S!6SwYDDJoUm;IdW+I?UEm$W)>gxGqL5D?D9eLUgfkF+{Lr_hQ${b#@AdB6#T)7&W4~|Q(Y>Ax z+na-SWf>!K*cqF!nK<_X)VQ(!9X^QPVkS&}H3y!ys9T$8ZDW&NSE4}cAmpgp5nQ(P zdtkV&!dQ>ZW?0G;%#7SC80`RbCJk)swNt%x%e03!@^uL`vWwD3-UTS#Cel>X^|b?$ zNV}v_{=^oyb;G~1ZZ2`kqcDyGDit#I9dKxxI#}U+Nt_B~j|CV)hKi05CAiFH!)1f8%3S1h=-(P`9TY{*a50ZE_v!1abj<+8=EvjYL~70Z8-E zJ8ba!jt#ElNS9;^W|v(nL`rqYuhbK(xxIruNt;unaFTZb3S*R4{4=(F!`^_^(@jD$lsG_|UkuD`Tl88qj2x0WJ?MR-?x3`FW=)oPzsSgp3lFXBcIARIS6&`l zbVlh>8e|z+4GRMwvBhzA)IlF?q#QNSbZLb#+l9bx9N5mKYFL&A6we;sQUn4Y?*fT? zh}1cnje~0TuN8-Vd*!oH8P==;Mhb$}g|CqG7U zUsLfpIl9Ni9|5HHD!kq;+=XQM@wF6Hvoww4f3Fi4_mW2q-(+&QRCW9I{$Ymb4;e!Y z@5|WEuY;h@uTyjhbF{eFUSSl0L2QO>u^PGIJAt(-%M}C;CPEZ3kkOQ?Bkc=z$fn3>P za(C}$p^!27UIKfV`G|r)Nb550$6O6o$@{=1Pi~uQcli=^wD5e>83*7Sc^Doo} zfXLdAenuW_O29Ei!Ow@xnI1TF&3NuTaf7?pTX(dTCUQH?Y0yV6k#ALnDr*S&u(0=Q zxo}ptHqEW}#UFRFRqjQ0V>bIwf26V3X1d`;x=;@h|I{_wsjEgvlX#nOMzT?QmCbh{ zquH+G<=IG_IyTBCuTo_ZRtY*Qgzm@Kh3$DgU7zT&n@XC-efDuc*$D@>;)FuiYXb0b zh41W0C%DJW-wmiIXN=>`O3q1ghw25>v)O-ZXsT-~+ozELMn#JRSRb1jN1U!WJGhJ{ zJS{sXMT}Y95m%I#Vm>yBGev#sm{D5Z!sXW#|1-{sRmBY}Sl^1#$aV`}ZcLPrjwJEv zx()cd^#YEx6-SU1b1RhTOyrecvNNq=PQY+;U~zh*7xaPaQTx)yKAQImAVs@4L)0e>PbapZP(|!Ha7mY)9t&Qm!|M|5)nb>mGe0}*H-Hi!0 zkG;s3MbCn<9%dpG9B1w>fo39d;9n;qVfs;d4;NSR~D(+%In?`d)ail z^}Cn(`dgPth$L!}vW{iSz>cg6+5@Cshj%Z{?KbPq4aK*{0c<+BP3H%q2FHa?c}h^I zh~kbCH~=q^L}zz6tCGt{TVKa^y_9xO7C7(9M`B>bAk{80{y{H}GrX<(X&0Eq1fuhHhFZf6I>*Z0;{fgI;B{QmreOd_ojuGkVo$5OL&<04Fm{4J!t-}>r+$lmB zdzTK8W3GfJBI2^vRf3GJB_+9=N(EGb;|-ylcYtp?Sa+HQ=| z4VJ@kDKjoft#z$6p9U?xiGGj?qV#=$&sz#jp+8^WLW9kkR_anwEd?vOKftN5K-n#VN_j7a`t3Z*8s^opSD z$8``*4i1?f6&SPv8Y|!E&K;B8$X9|B;T!UiV;l?E7;n_oHcQTAi!+(v>qV0hXN)q*3z8GLp(%L=a;Ve5^7;Z}o74=1 z8KO^hprQ{k?JbE#nl^mX>Yv*w?Bl6HEt3!_o^3S}xZC!b zlqUx*F)1Wo-+~N!9rdW?a^EW*Rk$YWI9!?O;t`{Xc{v3A@SHCJCwciTn}5ZwoWysc3ON#chY?EJUj@d6^pq)QElGM!&{ezm0g}>0)ylNv zQ0O1>ev{EmOv~{LazPA3#qv@PG>$GRIOAyKNKG$Blu8)USL4*9_JW4|}MxaXF-AzCfz-CN7;^wlFeoN(QAH-;nxL+uVd z{MQXE@x|_qvNTWalapz zIs7aNMrGCou#6uvzgQ>?{F)0_d?L)RNDz^;rmn*$kdPu}beLVHpjWp1T-!L%`b6s% z3u4<9&ipaHI0#No_NdPMStYD#B3Po(&40ymdO&DAK6&H=l#rg5WGO~f>l0FM?;YwL z-kk}z?IjVXytc8%Cvv{{orG|P9HC-jRGh&q2HeNyM*91yI9QK#u>rByo7^rj^syUZ z0U1WLh$MQ;8v0SKzl1DrOK3MyO=qjB35$AQ09IscmUTK4rgqbov(HavSv=<0^k~;e z`(j5P7FGRN+<+p|WBfaL-)be;aIOX5C5wVK#ZERx<9RkP?h(EZl1Sj9k)ffHkvjd= zT?jrq+j<2(!jT%-O)VwR`Y3-tlfbhQ`3tsZahLdC=nosi|InZRH)3M^UzFz`V%kSQ zknQcZlo}akA*ll(?gvx)Z?XTwqWAwwmKfOS|Cdp3h>DlI@)~B})QuzH8fv?3*3F0) z9n2pGcT}sYZ!(oJaIkCg@`{A9LEYRb-F5JG0S`V`j!(l7Sis{J+A8B6d~*DJ3I+u( z3q#Hw$eHFGQSdE^Y-SrV?lo+#r7p!K*~{j=9FDVHJKul*q`g~TGhRf}1bxB;a?;Cv z#9GCYom|IY8U{<{&Uhy}yfHff#>g`IT(o;>3_QA1WMXnfQeQDr4^O0-Q3<}!(+Fqa z(1^^n5LG)EZ6Yaz-Mi1m;rOF$Ya%qn(1?0+Yn&GyYB;ZOf&_JxcbnWC%i8!E2(ZIk^-I4x^Mlij+x8nx$rz96F#xSDdOtl~2`~43;a^ zu?)$L)4fF-9Mih8R{D*Tk?J+MCW?v}qH~SX6$A3mN6pMZ4a6x+DaEMJ7(SV%sKs*7 zIZ_*+OF|qJ8W~-$*ps_Smh2|_ksLThrm&TaF}%-wAwEAo;Y%u&%<1|L>VHxLdIGNp zUyQ&ThSUL7!&3}6t3|2LNz<{D!cda+T@{+olOaM*LUWLl4w(+=NN6X3D|oztpQb$Y zlIH9&(PG|zkDo_$KX{gDLB}Gzcfa}Xb4mY|VLEC`Ftr^N<)eL)y}7+UW+J91^%Iv^ z*nb|gap^fL9+9K^MRvO@b_J~NhEBgvc{amquCT(UQiP9M`;`5VvU?a=1QEG3%F=QO zym;Nd5=1}k$io|GxGJM!&%jUlK1OuXZ;Fq3mAh@GOikv%*A`N9~;z6-pjEC8?^WIXTSpPfCA(JeaaE-}MJb=!Bz zIXhr>-bB6!$(P!vd;P_tsj)$`l$u~|ikP0l=~b0b(*?%URUYiPOQ5Ci^fm+?DLSW# zApb*w|H2p@GW&uMn z_p}wl<@N#9NN((jC=YiQfH&QrAMXnqX=E0}iSaUo?||_F^$zdMPG*5S1j(|AGWllU zmWBV)Z;4;10Kwvc{FKns7Qn%etRVKrNA72uf~@cYT+sUTno z1jj=*$~O`rrz@^XQ&Bzw+%l&(0A9b#mv zD-dL;?(8IzKZNd=|0m+=PvxTmJEAZoT_MXm?p=JFb^n*tre4%-WBXpgf$7(hLpV>f zg0Qfbm{OEL#eFvB1I#NlU(l~YQk>s=H+emT7WxP`AZnz?b=`a>;^b=L&XRzoHd$C% zGP+o;FC@tK$RywaX6n2U>YSxLu+G!T=yll%>54Og6S^l8eP zA8SEN)U%)z^grUW4+5Tjg|&_YY8S_FUV+QzaT1lQ3oX_l)Wkn)7K!c zZN_kQOX!a?5L&Tk4DKgU&_A+k>qx!F5N zC_Y=-Hh-YTLa24Bb4Tyd!&+7ftZAE6RZ7eaqyn|gUFa*gl2@CmFr@jvM)?uUXh2>i z{=G(4e5~SS1ofD`6xYtq?KqPSQ~TNwYVqK*38icPI#m0$ug>??GynswN>vWJ>um9;n}^)yo(II?(g$3;HlTN zF9RtXk2S2Uqf^_hU?$t-)Lg@&1Z^sSTqU)>0A>kYV7A2uOHNP$h&G-+s|4Qmnizna zrw8;VjGn37YzY1Ry9?4h#rn55|7qn3(+c)E^XuYpl1&?$(21jGV$2HQ5;|EC{9!Js3~;%qIq++moDl3%E#!1 zHf`tB*>z&|2Y59rb?(1iv;Wb0@PE0&_4SqYmCYUW)%Wv301&o-68>B4|9FA=zh2>t z%nbj_-9JXvOBq@1PacA)xJ~3Fvkp(2W0{Uf%@o#U5joUb;Xm!wb*HK@Bmn~QbP+!) zM0_xPQZTV3hzJPiFrx5%%T`g#jpfS9W=)yv%BpKk`E@Ois%)Fvp^TR+&<)49?cBz@ zQR3qa+v}&#-mROT6N#`nIYENBZ%T)AiLFtsYYM5FRdigGZiR9NbH~SiQORJ`Ac!n3 zg)kCOGK6&aU81r(2lK<$%QL43L~No|+_(_1-O&+UVon?bM*u#tO;ONmU$jW_m&yHJ zQ^P~VK!4tG5`+c>0l_E&lp)YP<+0L{a(crN{hlRb7}xTrjifiZOL7^|$TLLjswYj+ z{x*w}D)k6du#jh*n};%xr$`4ZsB?3%u9_>3oIh2rdozq7RAEXo4ukDQ>9$i-adA3H zYz9`VKpRGvh?44+nLQ+rYPXCcJocG=J2Oj_?WI={3}2!WhK7@wB0ELA4-*mwjT5IL zQ$=7CrjZjzhRY~A)*{L?>m=a?P7Rza|vFA6YL zMD1^yZx51C4I28ngMFKJheU8lp!p#Gw@&OEs`&vRHQzlO2#6qAM(C!b*2y#ll@#nH zkJ!&p zT&LSw@-}E^%4Uh`bbRpJi5)lR%N(e;Dyzz^pg#S?0*TO~g7 z43PV0!jf#>_JQ`fU+Kw`qu7tRO^IxtR#8rdZm-${bXZ9&KIF<3JcshG6g;hZHyEagdl-uviF#EuN3QD-ZYXR+u#;Y^><|I8=>8 z4Y1jA9C%r$jAIX|N|(&RoWi$P6P)o53;cIzVe{tEKlS^q&7IqWSmJ5;fO)}(Pyw8^ zhKC7spSl}}Y+pN}T$|-j9P)ysLyX+-?)?Fz`Q~cR0QmWn&1?-TzId(62Y}GH2O@YECWw_mYsfmO0G67gP z7yh=wErGkNa${G7uLpuV+dY|ihF~&{;iR-L5IJy{C5G@a7l^o-Y#3J9ly-{L^DYkc zLAgjLN(w}z;T+YKIL@sSUq^YvBxg`}YFY56T=HtYb-9;z9hqN%ouHA2qxNTfyV>wl zv72BW<+q~>AuLFeD`d@H^AEufbbTH>atI@#?H-7>A=4Jl4?ly@ZvjRQv&HUPbE)jaS*ysx>4dy9Z7 zIhoJ9F>So_uE7njgM4GKfYB>t%U6kSym!oytg)gi^;0A#aLZMcEqzaX&^8FJiEFe~ z1*p62eM+6>*d6LEkk@sb>K{)OB=XV6P!3&5Zw3_UGPg#892Kr=v{Q# z#GIR&TiEbL8wQs*vsS4un)6f&pOfP872l>2=0b;fJgXWtnd zK(St2#e{`r(!b|Htj?Osm(5#hc22;1aPu-hlUz`7Ll?+CUA3Ev;7e1lEKTvXDZngLp_HVkJq1?n!MXtC< z%bx^3$NrO*40Nn!>TFNsCY3>E)t>{fKdZcK!w!Olh6W}-*3_Gk$(*sRYqt)zc1|&F zAD!(x`?QIxhZ0~8ig@9nZT?~uU!b@%yJQ_+5|qw`)FO{Vd%K=CY`8OVTCGM$8KF*% za;s0HJiDHebR1OJ zShdsm=W^Z}?~TRu?EiC!f1|0dUF;UjDf;T!tTi*SZYh`rvQ&rGQX^qn^XM?;f6bDU zZ{tLh*@3x_8hziyuBWYe7vi~Uz_EVBPJQ-->1yfEr=4r)Z=Y#P#fRiS;M?_D<}RPT zgs&|M;q#`GJfHHa;Ir-(%R_x4S79!yj5*;z)iP#bkzz;gkD_4q^e+~gCq#K)W14|C zaYicCJoSwo0whH?L~iX@St(;jH|K5sE(dpQpW=ezm%$m^B=C83oO>5K>+h-EXrk1A zx5}8nlyab;#a1&o{c8!!NFe=GCHjJMz@7Mj-*2kZQD6d=Hcf60p0fCY$4 z!a0cAS~0K7ncK3ux?a;xT<@#hC@-+ugd4`?*!PLO1_y5EIaTm(*LL&of{Dg zsh42J^*cWgJ{WX%zyK647BQw_=y_+Jg=S!hyqKA=dS+2XC>CORc|2$TVD_%?J=e;K zEgQCUv3}~T6F;@(=G@M$r9+#xr9|g1A_xVwgu|@FOk{*10(%k^F(G2j{jWHMnS+FSpX$Rg0+;@s7l09BJ&H32Fet< z3c{1AC1IIa^3Q@0V(X5Ct3)TVt7$|}IC@EaLqp4GWS}nhhLnJ(I^8b!`9jlJAe$Yg zH2lqB#Xev6tH-Y&Z+BQiA%3(&celJrRi;Z&Z6^BT2Bi%<%?uo=NJerJt;7UMq6IYp zaoHea5lorH8Z2;sY$G&kB_XSofRzH#+n}L}nF0f*vYELmc_wK%98C30@=;3Trhx1v`Vb4fsZ)?;1&mz@Ri9kkYaeaHP6Ilv?p=ygsZvc& zDI**z+$i#9tmn$+rcqVDEpOo%_zzWoUS=Msf(0?CLI!TqwcU8$hd);bg1my%)zJ=j z?S+5BeZBu?R%n$(TM?%g;&H!Tr#%_?l~aqby})gM5C71)`Oxv89lI-%jyLClbs`Br zm>oLk?QY<5yZ<)&QL|JoV{qIgrn7O554*B??wIx5tggxHtlGW@sg^dIE#|GiNe{ud#%()R}h1puuADEMyy|D#6wzwS>addB~CB7D@K)sfZE zauFDjtzj|=nrGHC22}1wig-6`YE9KNk;ZDHA!WW@B}DTjUf|~BD&Ks@X^1!9r7iAQYXEb!SgbO zX|s-dgzg~(#$7)=Z-9{niZZEvl)NfR-N8CllprUg;t?ecxeG{~hgpD(hjEAwz@!TA zF@qRZa;@ibagfkh-5N+}wlcGg8y}m722ZCSw)6Ih1m930wPsSKvp6#3#98jB1m9E$ zypu_k{>Yq`X(+x67f}$HVA*Yqj$s(R!(=U39wk+$Ml)|cA@GhSTOTpes4~&{XvR>C zf@Cf9n-%|wR^7E_e3)7l9lMjFsc`i*c~CW~oEZlPf9#$yKbCRz+WeZA_YzeMAIU`N zl+iSTmg(pjNBjG(cei*}Xc(x*+r-XD$;mjJYjW16QQbXYE+;PA5V9S2(W4jaEJOIi zKTRwcE`O+C$a;@)&wfwb5U(yQj35oGmOw6%$*=kjLa3zJScfZ{4!2L zUlK*44qv?+taM5um5}r3xmYE@E09a*xAhrpSV$;uK$3ENbZnIzD_ORyW~*?c;(L&E zUDV$rK<{|xQa>TJ@2cWr&em8fz{ZZM_$*Ljs5&y9roII)5RPP-RRZe_uP$w2T0JP*3Z zM~1qG9CYNnKbH`GEgubT46vjmZU$ziWz_cC6BHs{$8B?@QtTY4?ffisMJQ8?pYSdS za$l@0f~~(aBrK@zpaKy~k;#S{MxLEfub^x;jR=^{Qz##fbs3LyJ->KwrVc~fD<$B9 z?H3X|?ECAPoOGw3v~=_&BSU;B1O3%OUecu{?=OZSf6U#RxGaq-%2RkRPp0ji5Pbt2 zDK8ZAg`F_foB8ESzR$*pNJq%k1I#G`2yAyiKVGxWGn^QW*qHGx0#p)BaJS%>n zLbhS}lO$Il-|=Ip?D!7tf?un8`KsTLIs3zS6rI2516!z^;-FUezaA4k&_rYakCn%DRm74%$jF@FYxP8-s>f|W3;Ia8d zPOfgczpANqywy~<5@ttrRcUmG9c zKdyuZJgr{^ZpH^j6D`Xc%j?bk0%CE~Ol#(Bt*Y$I4H`UBU70j_!%F5#X9R9@xFdGE z96@RJrUML}yICjd(LRk?#t-jC)$YixUiJGF=l4Z~{CWTy;? zAr$lk%+2O6+bbB_sx!W+K`ePg8mPm9>_Cxyg{T-Ji1bAeaf{BzkgR&l$y%lb`kn(j zsBhW*jf`W;l!QD`;7MKKz5yjU|{tLuI$}JD) z>v#`RY$<@w8I3pQ2a^?vH;P;fGLUq)d}45C(xBJkN;?Qr$`Iq6h)(QBda) ze{s2GVtM!{Nnx5)qH?PQS?y_X|C$qE2Z0)oA=0a5pXD0QotKOA))qA$$pFeEsp zPFX5tILGjhE3BMGGcC#1ES%(k(Du>#cns(55NTu~(S!7N-PNUu{^+Y)B_&+AcAsG! zZqCN^=?bA)5S%m$PW;-w^Xf`N4^LeR3&U*>VhD?o0jNPE9lkW&C+}yCv3So^UNShu zau>gh9CDGc-Swpv*Q%K9PW|F+U|=EL!F!+Kt(lLuw9h)!-&^(Ml%z_jtLdxrbL*=F z);;xk3)d*=veHkY^-shcl376At-K8r&j=Rh^eMDu%C?lcax~|&J^@%fx3W=eeK)S0 zkQixb&iQE{S(g0CEA+^Jvb7o+wiFu^*L{RwylqeRYkRmgqrbFo&T)%6cMdm?ogxL~ zMEKu|zq+lp^$6Dn*5&=P2AC-!FL;!60(7j6%|$i32Dt99IHs|J5P|#^x8bRlTYjM7 zv&-8cigf+#0lfs4`hhPlKGZGK)=kx-=$RVl{``R8g3Y;dEc0w=6@sBT@dBCH0SE=uX{6i{=de)Dk`pM z%Qir;!XdaraQDK42bbU$tRT2c(BSS+I6)HJ-AUn41cC%DJP-u?6L>R<)4Hk1$Z|AxNpy7svpj#ELg_*@oKCS-p0$N?;~VQBh4*(*t5L zRXebyxrESb%LOel;t-*Z5^^<)tEP~E32OnZX*yV1`#R`g6a5vYKpw<);;k8YOYxzL zHj9ojCM*p9FQ-~if*tG&#rx|J8?5^`37Ws4OftIknI5 z9^I1Wriz~2;#g;?pB%>SYcwjsMgWnnt9Q18!t#9x`zxCUQgg4*=H(#L} zovs*=mOmdgEH>%%l-*@_daJYm)7MdL*y^%mXQlq;`;G+l57MwPXKCZNSp(C+2aa?l z=KV^JN-v!>uy&{R)-!6mOmfD5#}xj{#N+=>J^tCS=|2P!M8^CKMdra!I-*xJKVG-} zcg6p|2sjV$zw+VAXGwrOgt>t42I-Zzp9kN6Q&yP!KSdn>CkvU67s$i^KbTJO@(BOa zbmq{+-ho1oP~v=`|3S}jG4Qo&c|$%>Epq%3>4~P!fXo2l&E?@c(;U3 zv&Q^+dyjt7_z~-i8~I~aL!;r?$A|lzvS)0|+!#>iG+TKs;=n{dp? zzj9PxSIOf|u=j=KKoIvl=bvlWwL{slpF$fl+~|?(ewoJznGy8d2-jPtj|{otsW*Nr z95t1@?IDCB>xeQ}n{izzfsRORf@zYjcQ9CekGLOL{$>JPpCSpd&(uMnEbue4)1uzZ z^*@}ezES1^1r`JmTfQN&dm;-&sI}-ZC+Yv{T3D$(bNVr|1WV0UWEC%!z$6?V8rmmd z!i-te?OxZ(9gi^SIJwhM?ihMM+Xh=@V&M@;o^Bd{=T}n9LF;+NnlksBgHmVd{tEO} zZQ#SGIH|$o52w#Qx>~8(OSe6T6&0AREYY(+(w623_0sYv+o=pFKY;2ZT6WgfIgIhH6@F)FiA1Ud_*+ocW~;Lr3NYTK3!!-ts-uahjbm&|D(*WVwJE4qWXOeEh_ZwxU+9=sw1QC^H@wn z1K*Fpqr{=0M|0Z0K3I38w5{jITzgRIqo@Jz7_s1_PP!{fivy-`7?VW}pj{HbQIzhO z@bn|zSyYnTPglZwzLGUG5W4o`bz#>Oby|9qN&E=;qm)7Hf+w)_S#u;ge}Mk7l>W+N z;j7JJDEP6>gst(MuvOQzVKLW|5NWM?aZn`3Q{mj<;bfycIl8{STr9_xVrO|W94RMyy-L?C;?m@QeH0Pbu3I}r4 z>Wj}yi;AwBJ%riFjl9aPszH9mLTa!EgAc=4_kx4I?rgkiKi{%yCrgtr>+kX|hecGl zdhvu9w024A3mmNH+BHbg`RTV0r^js8ek}%rgiOBV=UHpv{NwC+izFNWQJ~=DaFx2* z{DRUTr!HN3_4+rj>Ro;nD6DF=TDa0-gvwgilhl3@a~RXRQa3E8D`4ULM{6v?m5)23 zgg^a!KoOFR-~_(D&g3Q5+K_>&_xGK)i1ubb`AQw|WX9H}wvY2`Q+l(K!HiK$R`8bN z;VyGdd3D6bL%5mrf%>3nOZ|>!CMvOiSqN>0Qei<@RSEA`-DEdPfR-OJmZ@a}5Zlv8gn9sPMR@6dvDgpHs21!aciP zagu^91vY)D*=t5KOksv9KHvnTG?9KRlMlDpe_Ur68ma6fwDDTkx}UU5t=KdIC1Imk zg4JU0(_eSqap9OOCZ1`9-sshesLm(}Vx{L)&+$z(iKQO|xqhFGO{{Q!84WLqoo*W& zX;1u`IDZYy-k{*T%PO-Y{EAht6k(d*NEN*!_;k2Zv>P6r&0sAgm&-KQ%gSCYH2iBP zwgZu;B7G3xDf8z_wzYzU5RIC;nSF2l{9J^ho=(E9yJjw`WB2Q`pt7wc)-6_m_7$nGIF8OS{Nq8a<7%DeKPYzjZG4)Ccgx0;{q&S^ZOc?I+fGs( z{(L!$^Fg#;3!t7LpKfT;Otp9C=Lu2^)Y|>pVj^**Y7VA6;C{=EtCwenNKL*5wN~Q# z;|W+rfI>3SHA8mo=2kdVf|~8mC3#|=iGEX;MKw>)g81{p!~61pz;8uDB~+r#CwIu+ zpR4@~a&KVeI3lq@EKi>{Ff1Fo8|r*A-1o%9Ffo8@GHuRl&)9#pF0_~2YJOfQEq|xT zZ;0xGsbN8U(;pG?lA8-%95Z^zUZLS#GyDurVJWBLR zuMMe;m8~Tjm1{G&<^mH4)DOC_`%y9b3Wo%#e%PekUV0yb!whN6qqdA%cWzt^wY-mq zmnyv_aTQL&7_=CT_hre9+htE>-NDT1B$fmq0vqEZgT5?zI00vyTHO1#CNUn7jj@r} zsx;D!M3eE-=*i$C)xNxwXgSGA(5A+*c;vV&_g?}V0@_S zA&}FDj=dNo7-NK|%oUNL1Gr%GM#%iYt~@hQQG;!d>PKFWLU>QyDY#OU!Nmf8@($D5$F?)fAtc(-9J#={n~f6D2z8T zaJpaa;zJ*zahl=V8$H%_q_l6=yi>ci3_lctuyO_Z3K60sD3C@rLNI@6eWRJ5c1Me} zod%?mj5Oo+(JC*!B7F;#PnP+>RTk4%iOct{=FOh4+>(X|P(6(pjXu(rVu*gV4t+`Z zM~GAug@O4OjKAE==w)Aevwv*EAg|=(#YYfWT@iK}PG6Y|kzq+uyk`1@+RDCxvid$O zRY{hjfGn}jO{@;{N+}lqR0C1-!&?M%0;_WQ=r62oICYxAsQ6|Y>+GcQ()4X#MrnwQ z@l9nd_*?Q9041W>coZ+mbwsXc?qr&OqLLcT019ZiNa1aTbx3A=>&PU75UN__dRTDP z2_e722t${QIu1F0-9o<`m4)=H@CCDh*A6V4uPMqupADpYqRhih>Xi^&+2%qgq@#d0$BdVdE3+z5#*!lvy z4Kxs@X?_Q&;7GMRNF%{qq)ta_qu$->eBn06JCoC+N*d!r58q6QD}~xjPR}fQ_<%Wl z;c$q#Z~mkHH--67=mE&IYb3V#snI4VTD37ur;;VPVuV$lq{e`7(a~7U4w|5u!%&%RwZd%R8E24QB|78;cCbq^ zDYlw{Q1s9(dL59-)>z(h?xwbEjec6?3r1_w#gRj!t)3McJIm|-ENHA!B80na)pER$ zE33m-Np1!HU4&0ESX0s5!l>%yKrp}KO{^U7$NA7y)@}dLIAKT0e)xEXMvs4&2&-Z1 zPY23xSG&jZBVd5!Ri&ZK+v-tE;v4Cla*fRUE^f9nhgjm0Em%i)%hrQ6mIVWT5d;40 z#JLXE>{9GK{|F&ggpq#vaOY)d%hsdQ)aYfzr~7w? zO9YX0iQg<(Sv86m> zB2lS;yNOeF-Vk;h+h_MY{QAdBkps$3e|T$?fKd}%WZ5{9!=70At9)0T(B9Gx>!9j9 zKfUexiwa%~C1HO@1frtXzC$7lNxqgGt}$M&vBw;@Gr`<6%yX=bozkzIA>V_c1PCN3 z6S~?nSg!+h-^ObwmUQ;DYGj={8HAe$CjBHncex-0Ctd9NH?)oACp4aB@(5Ur7w`k9 z<0q4NATc&=+@YK8R^t^maQ6#I<&Wxr_^oJuc~;~VN!{~m%Jb*ALE-9oV`;l)>OsggyIuQLW$Hb9El zTz8I%^cXozvki@nFC17lw~-WpmuN|*>=6EnqfqQ=(B32aovrX%3nB2!|C<3ZekX>?0cRd_Di-b4MftT#-c+c1iFZfaf7R$f(S)R2(EZEw^S~a zxbfWNdO&S?MZ!rBn0M!#H+atY4jCB(FZkPQrjE-M)0uxIC%gja4W&~&;}gHwsA z;gcBnOI_coYd!{8Z6rn&Li&NH0{y)auR~KG#Wd&`ij(t$yV~qc&NE_M%QyQNw92SJ zk(i`dw|Bb2rietjjZ^wwgM6AibWMNd@Tuhs25!rOLGtn~Wl@y=1T-y_Nkr1jCJgt} ztLvpkzZ+rn(t{gTf*;xWPC6m}(QbEczNp*xExa;=g-NQ`nZfHz9T)*TS59rCa++V) zV%)Q(Tbxp=6)epgH}s)+t=WmyJtI|AcJ{_%Ng3yBj4MS_-U!Y=6=y!7sr-_TSF))l zWur%3`otsOBur{0&r44)PMsh`O1F#^ZR5WR+_Hzqfh{*UQD8I#6>;%#cu?jv`6MX@ zL#KgZdCW`3V(m`NQ4YZg#PN@hTD_?xTf8raz={l52>vot4 z>$y#yiqXIAa*wIGWQJa3Myp0-ddX}qD)LXLEs2^}QCrCRax~TtJCuu)Cu_dpq{oUk zo{bHzm;XSHoWnm8>Zs9hI3$2r%*(^Ov< ziB>SCCUxr0+0rs47H61bil3CjMK=3x_W#QVFx1dr>#uUN{Mk?IAVY-$8wYShDYP9Pft}*q}S-eO&c+-oVBY&|58mikEfO z$_~5V2OV0=R~el-`Nt>tzvHqS9AE6f?PeA}Hagzluc%I5cSgJAbS(A#d>~Ow`_4Kh zwg6WY%*HfT3Az|D4TUfJYQFauhN8s69gbJl#qP5o{2FfZ{UcKr*~z_kmlLN}xN{C4 zNgjpUDdTH{-aao7sE|Z#oF%F;9ml(Ra_d|9p+3J{%MZ@?!jAde*Lp)wOQVDVZ9kpz zBc=2YMsS#715dWCM8>Ao&ky=nHtpPy=KG{feS|`m(i1CBm7cij0ZCmH>?nFO$|8~< zX#e!yF;!tvceJ#mS@r9&F!#?}2~uq8262+uAr7ONX6?G9b-{6>IW^_!I|eY>HFx=I z(`?)wMMl0$+WI_miEsTz603Yx^p#F957zFP3_&8N`}$M&tYficTW`SbF*zT>w&FO{S3x(!gxxaQCvoi@ zzCfuSK3hIO(u;2yy*?lLRE$b$btc2S7hT|fvqMq8C>-%ecdL0b(0<fy569<-k;Q4Hsnko8RdR-Xr%JjmWt8{{p0y@f3#Dk$~JP1gycLz}+f4P2PR1Xt-^#AAA&AZF2V zr^IxjFR~(`66!(7j@&Uq5NWI&YJR*{VwKXwr0**WaSu53or8xM2Ov=u*Kb4Y*0V2KJ#>Tb&`#j-7Zev(sfF7kgE41Ubyjo91lDar&i@^P`fi19J5Z%fp!<;=_aQR zPGa+~teS%6o64-3>_Z=>sIFQ(jDC z0($XkuG{C~q*ZshE|G)_hdB;zx8ly{50g-?RJ^&A>_wVAJ1z71%y@ zrdQhEM-gSM?`*%ke#NU|G-T5o7VxZkw`UEcqE66TxOvvYW94!WVu z#l&AmKDw5uvF!QUiPfIRyFU(Y0bbsXRA#Lg=jP)Ga!FMriXvZoBt(FuFwTI^ubfK? z9-3VRv5hCJw|ZmlzV=$nLD6{%!WJ3 zAa|-EcZw3KNmBaXY~@}c&IquQJbiqJd|+_RqWIZ4Fdjhl)tYs7imlvifQ;}DwsslD zN(3M<58$NCI?H@>`DfQ7t9XHag4Ws-n`e1~mN8#O8}fR~-aRThv%p_0@_n|9{|(Qp z$1sG{XXjiQ!_(Lu+z(%6;#OGX_@Qf_*rUCF%4Y`GY)}((h@H1lqW*3u5Z@M#JM{S6 z25`%0^h0dghQ=D*HV#W?QYUNkyTpWrHyz>$^PL%`2raj)6w#50W|{F&-z*kEmB9L% zVe>?)=u5DJXh!_gEwcQ>(ZOYD&OE@#7T5T;VoPp8;)OaCx#~P5= zqpm*Fcp*ml-9SXGw>0%aq+69ZFNR*=Rm-r^+^H^`4;0|URV+8WCK>SLg9)O}`9ai6 z?w}h#208965w{!b8;geGsQsBH-c9OZZ^mDHi^Fm&dKhXfzru{+7uiXA1lV zYYwJqRaF=+@F+2?rIp5^s7V45u>Tq7BxCIm!L1hC1192Fqva3;tO+yKa8-R@c{@$y) z5I4e%L5F*0`ZMBz>)ks+J&CAH&e#cK$=g(};+fCyX(s~qXxk^V=PnBfT=!DqAMIQMo=2uJCt=d;iK<#|pkbP&Es_(yUNo9;PWcAVrI zcc{(L8+QpTigp)&w1jQ3=ADjrF+>uC>n+$%$~Q7c`p4Vsmpnt~+54)=0;R)=;_J!Y zt_LsOC66Q%b*gmv+v9LLGU3w#xeWYjv1#6&?kajzha_ExBwu%%P!4nRq z*3(tGFJBlBXb+XdsT3)WaYNMoyLr!&`#s-B77HT6$9I5x+g`QS!A`b+zNk=d4!#ZEr5WNpvu;hj@1+hDdD^-eJvDRd33NGrBJb&k zyj#I}?!;xhJ(g&%Eo>dPwqM)0G3n_qAB8byj9wa-K!tCD5M(zHUH-Mf^)i(EzdBs{ zS|DpKMOh;;ZUF%xpM|BcprARwkN}7qXu%`I3jzu9a+`B=gRCqh{`W6TxU`&|JpljE z>S}Q*I$1l@{G*?y#r46~7evD&4CK-?;-TTA;Wham`ey>%|FjD(Fr(;#=}HoDdK@cY zg-K@_8$fCiZH9(V8!aGot57!baegw26PC*F$#5LTjauTfrawFJW32TPLFxNd`A@}u&%5`sA zEl8dE5A_pt^rJ;z(suh++EA}IB`_^H=C;h!&;G9JF{RVm==2$w99JnW8cCFB{dHHi zoCa^PCObRX-fhJ_)pcurZ=dC;Pi&FZHhgfheOz~7a~oO{UVau4HC@VL(iVAc|ITI! zRZN#nFiOE{$<tI!_pZKQ$ z!^_`#```BV5%qpqYCc}9-u3MLO%5tGxKy6)7~U6}v(Z5fGL+Q(nbsyc z9w(+L>SadESVv7=jx8tqgfu&5clWRVt-FW0n}?4Z$Qr=IEBGRq1u!tksmlZY4TzM$ Awg3PC literal 0 HcmV?d00001 diff --git a/all_future_model_interpretation.tex b/all_future_model_interpretation.tex new file mode 100644 index 0000000..970b73d --- /dev/null +++ b/all_future_model_interpretation.tex @@ -0,0 +1,393 @@ +\documentclass[11pt]{ctexart} + +\usepackage[margin=1in]{geometry} +\usepackage{amsmath, amssymb} +\usepackage{booktabs} +\usepackage{enumitem} +\usepackage{hyperref} + +\title{Interpreting the All-Future DeepHealth Model\\ +all-future DeepHealth 模型的解释边界} +\author{} +\date{} + +\begin{document} + +\maketitle + +\begin{abstract} +The all-future DeepHealth model should be interpreted as a +history-conditioned incident disease and mortality risk model. At a query time +\(t\), the hidden state \(h(t)\) summarizes the observed history up to that +time, and the model estimates future first-occurrence risks for diseases in the +model vocabulary, together with future mortality risk. The model does not +directly estimate current clinical disease burden, organ damage, frailty, +disease severity, recurrence risk, or disease-specific weights. Those +quantities require labels, mappings, weights, or supervision that are not part +of the present model. + +\medskip + +all-future DeepHealth 模型应被解释为一个基于既往轨迹的未来新发疾病和死亡风险模型。 +在查询时刻 \(t\),隐含状态 \(h(t)\) 汇总了截至该时刻的已观测历史;模型输出的是 +模型词表内各疾病的未来首次发生风险,以及未来死亡风险。当前模型并不直接估计当前 +临床疾病负担、器官损伤、衰弱程度、疾病严重度、复发风险或疾病特异性权重。这些量 +都需要当前模型之外的标签、映射、权重或额外监督。 +\end{abstract} + +\section{English} + +\subsection{Model object} + +For individual \(i\), let \(\mathcal{H}_i(t)\) denote the observed history up to +query time \(t\). The all-future model produces +\[ + h_i(t) = f_\theta(\mathcal{H}_i(t)), +\] +and, for each disease token \(d\) in the modeled disease vocabulary +\(\mathcal{D}\), estimates a future first-occurrence risk over a horizon +\(\tau\): +\[ + p_{i,d}(t,\tau) + = + P_\theta\!\left(T_{i,d}\in(t,t+\tau]\mid h_i(t)\right), +\] +where \(T_{i,d}\) is the first observed occurrence time of disease \(d\). If the +model includes a death endpoint, it also estimates +\[ + p_{i,\mathrm{death}}(t,\tau) + = + P_\theta\!\left(T_{i,\mathrm{death}}\in(t,t+\tau]\mid h_i(t)\right). +\] + +The disease sequence is a first-occurrence sequence. Therefore, from the input +history itself we know +\[ + m_{i,d}(t)=\mathbf{1}\{T_{i,d}\le t\}. +\] +This historical indicator is not learned by the model; it is read directly from +the event history. + +\subsection{Masking already occurred diseases} + +For a disease that has already occurred before or at \(t\), the model output for +that disease should not be interpreted as recurrence risk or current disease +activity. For future incident disease summaries, already occurred diseases +should be masked: +\[ + p^{\mathrm{new}}_{i,d}(t,\tau) + = + \left[1-m_{i,d}(t)\right]p_{i,d}(t,\tau). +\] + +\subsection{Directly supported model-derived quantities} + +The current model directly supports the following quantities. + +\paragraph{Disease-specific future first-occurrence risk.} +For each modeled disease \(d\), +\[ + p^{\mathrm{new}}_{i,d}(t,\tau) +\] +is the estimated risk that disease \(d\) newly appears within the next +\(\tau\) years, conditional on the history summarized by \(h_i(t)\). + +\paragraph{Future mortality risk.} +\[ + p_{i,\mathrm{death}}(t,\tau) +\] +is the estimated probability of death within the next \(\tau\) years. Death is a +terminal endpoint and should not be treated as an ordinary disease burden +weight. + +\paragraph{Probability of being alive with no new modeled disease.} +Using the model's disease-specific and death risks, one can summarize the +probability of no new modeled disease and survival over the next \(\tau\) years: +\[ + S^{\mathrm{all}}_i(t,\tau) + = + \left[1-p_{i,\mathrm{death}}(t,\tau)\right] + \prod_{d\in\mathcal{D}} + \left[1-p^{\mathrm{new}}_{i,d}(t,\tau)\right]. +\] +Equivalently, if the model is represented through cumulative hazards +\(\Lambda_{i,d}(t,\tau)=-\log[1-p_{i,d}(t,\tau)]\), +\[ + S^{\mathrm{all}}_i(t,\tau) + = + \exp\left( + -\Lambda_{i,\mathrm{death}}(t,\tau) + -\sum_{d\in\mathcal{D}} + [1-m_{i,d}(t)]\Lambda_{i,d}(t,\tau) + \right). +\] + +\paragraph{Probability of being alive with no new disease in a specified set.} +For any analyst-specified subset of disease tokens \(G\subseteq\mathcal{D}\), +\[ + S^{G}_i(t,\tau) + = + \left[1-p_{i,\mathrm{death}}(t,\tau)\right] + \prod_{d\in G} + \left[1-p^{\mathrm{new}}_{i,d}(t,\tau)\right]. +\] +This is a subset-level future disease-free survival summary. If \(G\) is called +an organ system, the disease-to-organ grouping is external to the model and +must not be described as a learned organ score. + +\subsection{Historical counts are not model-derived burden} + +One may count observed historical diseases: +\[ + B^{\mathrm{history}}_i(t) + = + \sum_{d\in\mathcal{D}}m_{i,d}(t). +\] +This quantity is a direct count from the input sequence. It does not require the +model and should not be presented as a model-derived disease burden score. +Without disease severity labels or disease weights, it treats all disease +tokens equally. + +\subsection{What the current model does not estimate} + +The current model does not directly estimate: +\begin{itemize}[leftmargin=1.5em] + \item current clinical disease burden; + \item organ damage, organ age, or organ functional reserve; + \item frailty or frailty weights; + \item severity of a newly diagnosed disease; + \item recurrence risk after first occurrence; + \item relative clinical importance of different disease tokens. +\end{itemize} + +These interpretations require additional labels, mappings, weights, or model +training objectives. Using the present all-future model to claim these +quantities would be over-interpretation. + +\subsection{Post-onset prognosis for the same new disease} + +For a disease \(d\) that newly occurs at time \(T_{i,d}\), the model cannot +infer the clinical severity of that disease itself. However, after the disease +has entered the history, one may query the model again and compare subsequent +future risks: +\[ + p^{\mathrm{new}}_{i,e}(T_{i,d},\tau),\quad e\ne d, + \qquad + p_{i,\mathrm{death}}(T_{i,d},\tau). +\] +This supports a prognosis-oriented statement: the same incident diagnosis may +be followed by different future disease and mortality risk profiles in people +with different prior trajectories. It should not be described as direct disease +severity. + +\subsection{Future extension with reliable recurrence data} + +The above interpretation is constrained by the first-occurrence nature of the +current disease sequence. UK Biobank does not provide a reliable longitudinal +record of disease recurrence, relapse, repeated admissions, treatment +escalation, or episode-level severity for the modeled disease tokens. Therefore, +the present model cannot be used to estimate recurrence risk or ongoing disease +activity after first onset. + +If reliable recurrence or repeated-event data were available, one could define a +different modeling target. Let \(N_{i,d}(t)\) be the counting process for all +episodes of disease \(d\), not only its first occurrence. A recurrence-aware +model could estimate the future increment +\[ + P_\theta\!\left(N_{i,d}(t+\tau)-N_{i,d}(t)>0 \mid h_i(t)\right), +\] +or the expected number of future episodes +\[ + E_\theta\!\left[N_{i,d}(t+\tau)-N_{i,d}(t)\mid h_i(t)\right]. +\] +For individuals with \(m_{i,d}(t)=1\), this would support a genuine +post-onset interpretation of future recurrence or disease activity. For +individuals with \(m_{i,d}(t)=0\), it would remain an incident disease risk. + +With such data, the model could also separate three clinically different +quantities: +\begin{itemize}[leftmargin=1.5em] + \item incident risk: the first future onset of a disease not yet observed; + \item recurrence or repeated-event risk: future episodes after a disease has + already occurred; + \item mortality risk: a terminal endpoint that competes with future + non-fatal events. +\end{itemize} +If recurrence episodes were linked to reliable episode-level severity labels, +such as hospitalization intensity, treatment escalation, or validated severity +grades, then a further supervised model could learn severity-aware prognosis. +These extensions would require new data and new training targets; they are not +available from the current all-future first-occurrence model. + +\section{中文} + +\subsection{模型对象} + +对于个体 \(i\),令 \(\mathcal{H}_i(t)\) 表示查询时刻 \(t\) 之前已经观测到的历史。 +all-future 模型产生 +\[ + h_i(t)=f_\theta(\mathcal{H}_i(t)), +\] +并且对模型疾病词表 \(\mathcal{D}\) 中的每个疾病 \(d\),估计未来 \(\tau\) 年内的首次 +发生风险: +\[ + p_{i,d}(t,\tau) + = + P_\theta\!\left(T_{i,d}\in(t,t+\tau]\mid h_i(t)\right), +\] +其中 \(T_{i,d}\) 是疾病 \(d\) 的首次观测发生时间。如果模型包含死亡终点,则同时估计 +\[ + p_{i,\mathrm{death}}(t,\tau) + = + P_\theta\!\left(T_{i,\mathrm{death}}\in(t,t+\tau]\mid h_i(t)\right). +\] + +当前疾病序列是 first-occurrence 序列。因此,从输入历史本身即可得到 +\[ + m_{i,d}(t)=\mathbf{1}\{T_{i,d}\le t\}. +\] +这个历史发生指示量不是模型学出来的,而是直接从事件历史中读出的。 + +\subsection{已经发生疾病的 mask} + +如果某个疾病在 \(t\) 之前或 \(t\) 时已经发生,那么该疾病对应的模型输出不应解释为复发 +风险,也不应解释为当前疾病活跃程度。在汇总未来新发疾病风险时,应对已经发生过的疾病 +进行 mask: +\[ + p^{\mathrm{new}}_{i,d}(t,\tau) + = + \left[1-m_{i,d}(t)\right]p_{i,d}(t,\tau). +\] + +\subsection{当前模型直接支持的派生量} + +当前模型直接支持以下几类量。 + +\paragraph{疾病层面的未来首次发生风险。} +对每个模型内疾病 \(d\), +\[ + p^{\mathrm{new}}_{i,d}(t,\tau) +\] +表示在 \(h_i(t)\) 所总结的历史条件下,疾病 \(d\) 在未来 \(\tau\) 年内新发生的风险。 + +\paragraph{未来死亡风险。} +\[ + p_{i,\mathrm{death}}(t,\tau) +\] +表示未来 \(\tau\) 年内死亡的概率。死亡是终末结局,不应作为普通疾病负担权重加入疾病 +负担求和。 + +\paragraph{未来无新病且存活的概率。} +利用疾病层面风险和死亡风险,可以汇总未来 \(\tau\) 年内无任何模型内新病且存活的概率: +\[ + S^{\mathrm{all}}_i(t,\tau) + = + \left[1-p_{i,\mathrm{death}}(t,\tau)\right] + \prod_{d\in\mathcal{D}} + \left[1-p^{\mathrm{new}}_{i,d}(t,\tau)\right]. +\] +如果用累计 hazard 表示,令 +\(\Lambda_{i,d}(t,\tau)=-\log[1-p_{i,d}(t,\tau)]\),则 +\[ + S^{\mathrm{all}}_i(t,\tau) + = + \exp\left( + -\Lambda_{i,\mathrm{death}}(t,\tau) + -\sum_{d\in\mathcal{D}} + [1-m_{i,d}(t)]\Lambda_{i,d}(t,\tau) + \right). +\] + +\paragraph{未来无指定疾病集合新发且存活的概率。} +对于任意由分析者预先指定的疾病 token 集合 \(G\subseteq\mathcal{D}\),可以定义 +\[ + S^{G}_i(t,\tau) + = + \left[1-p_{i,\mathrm{death}}(t,\tau)\right] + \prod_{d\in G} + \left[1-p^{\mathrm{new}}_{i,d}(t,\tau)\right]. +\] +这只是指定疾病集合层面的未来 disease-free survival 汇总。如果将 \(G\) 称为某个器官系统, +那么疾病到器官的分组来自模型外部,不能描述为模型学到的器官评分。 + +\subsection{历史计数不是模型派生的疾病负担} + +可以计算历史已经发生过多少个模型内疾病: +\[ + B^{\mathrm{history}}_i(t) + = + \sum_{d\in\mathcal{D}}m_{i,d}(t). +\] +但这个量只是从输入序列直接计数,不需要模型,因此不应表述为模型派生的疾病负担评分。 +在没有疾病严重度标签或疾病权重时,它默认所有疾病 token 等价。 + +\subsection{当前模型不能估计什么} + +当前模型不能直接估计: +\begin{itemize}[leftmargin=1.5em] + \item 当前临床疾病负担; + \item 器官损伤、器官年龄或器官功能储备; + \item 衰弱程度或衰弱权重; + \item 某个新发疾病本身的严重程度; + \item 首次发生后的复发风险; + \item 不同疾病 token 之间的相对临床重要性。 +\end{itemize} + +这些解释都需要额外标签、映射、权重或新的训练目标。用当前 all-future 模型直接声称这些量, +属于过分解读。 + +\subsection{同一新发疾病后的预后差异} + +对于在 \(T_{i,d}\) 时刻新发生的疾病 \(d\),模型不能推断这个疾病本身的临床严重程度。 +但是,当该疾病已经进入历史之后,可以再次查询模型,并比较之后的未来风险: +\[ + p^{\mathrm{new}}_{i,e}(T_{i,d},\tau),\quad e\ne d, + \qquad + p_{i,\mathrm{death}}(T_{i,d},\tau). +\] +这支持一种预后层面的表述:同一个新发诊断出现在不同既往轨迹的人身上,可能对应不同的 +后续新病和死亡风险结构。但这不应被表述为模型直接判断了疾病严重度。 + +\subsection{如果有可靠复发数据,未来可以做什么} + +上述解释受到当前 first-occurrence 疾病序列的限制。UK Biobank 并没有为模型词表中的 +疾病提供可靠的纵向复发、复燃、重复住院、治疗升级或 episode 层面严重程度记录。因此, +当前模型不能用于估计首次发病后的复发风险或持续疾病活动。 + +如果未来有可靠的复发或重复事件数据,可以定义一个不同的建模目标。令 \(N_{i,d}(t)\) +表示疾病 \(d\) 的所有事件计数过程,而不只是首次发生。一个考虑复发的模型可以估计未来 +事件增量: +\[ + P_\theta\!\left(N_{i,d}(t+\tau)-N_{i,d}(t)>0 \mid h_i(t)\right), +\] +或者估计未来事件次数的期望: +\[ + E_\theta\!\left[N_{i,d}(t+\tau)-N_{i,d}(t)\mid h_i(t)\right]. +\] +对于 \(m_{i,d}(t)=1\) 的个体,这才可以支持真正的发病后复发风险或疾病活动解释;对于 +\(m_{i,d}(t)=0\) 的个体,它仍然对应未来首次发病风险。 + +在这样的数据条件下,模型可以区分三个临床上不同的量: +\begin{itemize}[leftmargin=1.5em] + \item 新发风险:尚未发生疾病的未来首次发生风险; + \item 复发或重复事件风险:疾病已经发生后的未来 episode 风险; + \item 死亡风险:与非致死事件竞争的终末结局风险。 +\end{itemize} +如果复发 episode 还带有可靠的 episode 层面严重程度标签,例如住院强度、治疗升级或经过 +验证的严重程度分级,那么还可以进一步训练有监督的严重程度相关预后模型。但这些扩展都 +需要新的数据和新的训练目标,并不是当前 all-future first-occurrence 模型已经具备的能力。 + +\section{Recommended wording} + +\paragraph{English.} +The all-future model is a history-conditioned incident disease and mortality +risk model. Its outputs support future disease-free survival summaries over the +modeled disease vocabulary, but do not directly quantify current disease +burden, organ damage, frailty, or disease severity. + +\paragraph{中文。} +all-future 模型是基于既往轨迹的未来新发疾病和死亡风险模型。它的输出可以支持模型词表 +范围内的未来无新病且存活概率汇总,但不能直接量化当前疾病负担、器官损伤、衰弱程度或 +疾病严重度。 + +\end{document} diff --git a/build_organ_involvement_label_mapping.py b/build_organ_involvement_label_mapping.py deleted file mode 100644 index a23f89c..0000000 --- a/build_organ_involvement_label_mapping.py +++ /dev/null @@ -1,157 +0,0 @@ -from __future__ import annotations - -import csv -import re -from pathlib import Path - - -LABELS = Path("labels.csv") -OUT = Path("organ_involvement_label_mapping.csv") - - -ORGANS = [ - "brain_neurologic", - "heart", - "artery_vascular", - "immune", - "intestine_digestive", - "kidney", - "liver", - "lung", - "muscle_musculoskeletal", - "pancreas_endocrine", - "adipose_metabolic", - "female_reproductive", - "male_reproductive", - "neoplasm", -] - - -def _code_key(code: str) -> tuple[str, int, str]: - code = code.strip().upper() - match = re.match(r"^([A-Z])(\d{2})(?:\.?([A-Z0-9]+))?", code) - if not match: - raise ValueError(f"Invalid ICD-10 code: {code!r}") - letter, number, suffix = match.groups() - return letter, int(number), suffix or "" - - -def _in_range(code: str, start: str, end: str) -> bool: - c_letter, c_num, _ = _code_key(code) - s_letter, s_num, _ = _code_key(start) - e_letter, e_num, _ = _code_key(end) - if s_letter == e_letter: - return c_letter == s_letter and s_num <= c_num <= e_num - return ( - (s_letter < c_letter < e_letter) - or (c_letter == s_letter and c_num >= s_num) - or (c_letter == e_letter and c_num <= e_num) - ) - - -def _matches_any(code: str, ranges: list[tuple[str, str]]) -> bool: - return any(_in_range(code, start, end) for start, end in ranges) - - -def organ_for_icd10(code: str) -> tuple[str, str]: - code = code.strip().upper() - if not re.match(r"^[A-Z]\d{2}", code): - return "", "unmapped_non_icd10" - - if _matches_any(code, [("C00", "D48")]): - return "neoplasm", "neoplasm_c00_d48" - - if _matches_any(code, [("F00", "F09"), ("G00", "G99"), ("I60", "I69")]): - return "brain_neurologic", "f00_f09_g00_g99_i60_i69" - - if _matches_any(code, [("I00", "I09"), ("I20", "I52")]): - return "heart", "i00_i09_i20_i52" - - if _matches_any(code, [("I10", "I15"), ("I70", "I89"), ("I95", "I99")]): - return "artery_vascular", "i10_i15_i70_i89_i95_i99" - - if _matches_any(code, [("A00", "B99"), ("D50", "D89")]): - return "immune", "a00_b99_d50_d89" - - if _matches_any(code, [("J00", "J99")]): - return "lung", "j00_j99" - - if _matches_any(code, [("K70", "K77")]): - return "liver", "k70_k77" - - if _matches_any(code, [("K85", "K86"), ("E10", "E16")]): - return "pancreas_endocrine", "k85_k86_e10_e16" - - if _matches_any(code, [("K00", "K69"), ("K78", "K84"), ("K87", "K93")]): - return "intestine_digestive", "k00_k69_k78_k84_k87_k93" - - if _matches_any(code, [("N00", "N39")]): - return "kidney", "n00_n39" - - if _matches_any(code, [("N70", "N98"), ("O00", "O99")]): - return "female_reproductive", "n70_n98_o00_o99" - - if _matches_any(code, [("N40", "N53")]): - return "male_reproductive", "n40_n53" - - if _matches_any(code, [("M00", "M99")]): - return "muscle_musculoskeletal", "m00_m99" - - if _matches_any(code, [("E00", "E09"), ("E17", "E90")]): - return "adipose_metabolic", "e00_e09_e17_e90" - - return "", "unmapped_no_organ_rule" - - -def main() -> None: - rows = [] - with LABELS.open(encoding="utf-8") as f: - for i, line in enumerate(f): - line = line.strip() - if not line: - continue - parts = line.split(maxsplit=1) - code = parts[0].strip().upper() - name = parts[1].strip() if len(parts) > 1 else "" - organ_id, match_source = organ_for_icd10(code) - rows.append( - { - "token_id": i + 3, - "label_code": code, - "label_name": name, - "organ_id": organ_id, - "organ_label": organ_id, - "organ_weight": 1.0 if organ_id else 0.0, - "match_source": match_source, - "mapping_source": ( - "organ-age-inspired clinical systems based on " - "Oh et al. Nature 2023; single-label ICD-10 rules" - ), - } - ) - - fieldnames = [ - "token_id", - "label_code", - "label_name", - "organ_id", - "organ_label", - "organ_weight", - "match_source", - "mapping_source", - ] - with OUT.open("w", newline="", encoding="utf-8-sig") as f: - writer = csv.DictWriter(f, fieldnames=fieldnames) - writer.writeheader() - writer.writerows(rows) - - mapped = [row for row in rows if row["organ_id"]] - print(f"labels: {len(rows)}") - print(f"mapped_labels: {len(mapped)}") - print(f"unmapped_labels: {len(rows) - len(mapped)}") - print(f"organs: {', '.join(ORGANS)}") - print(f"output: {OUT}") - - -if __name__ == "__main__": - main() diff --git a/build_uk_hfrs_label_mapping.py b/build_uk_hfrs_label_mapping.py deleted file mode 100644 index 0fb62c9..0000000 --- a/build_uk_hfrs_label_mapping.py +++ /dev/null @@ -1,215 +0,0 @@ -from __future__ import annotations - -import csv -from pathlib import Path - - -LABELS = Path("labels.csv") -OUT = Path("uk_hfrs_label_mapping.csv") -MISSING_OUT = Path("uk_hfrs_missing_label_codes.csv") - - -# Source: Gilbert T, Neuburger J, Kraindler J, et al. Development and -# validation of a Hospital Frailty Risk Score focusing on older people in -# acute care settings using electronic hospital records. Lancet. 2018. -# Supplementary appendix, Table A2. -UK_HFRS_WEIGHTS = { - "F00": 7.1, - "G81": 4.4, - "G30": 4.0, - "I69": 3.7, - "R29": 3.6, - "N39": 3.2, - "F05": 3.2, - "W19": 3.2, - "S00": 3.2, - "R31": 3.0, - "B96": 2.9, - "R41": 2.7, - "R26": 2.6, - "I67": 2.6, - "R56": 2.6, - "R40": 2.5, - "T83": 2.4, - "S06": 2.4, - "S42": 2.3, - "E87": 2.3, - "M25": 2.3, - "E86": 2.3, - "R54": 2.2, - "Z50": 2.1, - "F03": 2.1, - "W18": 2.1, - "Z75": 2.0, - "F01": 2.0, - "S80": 2.0, - "L03": 2.0, - "H54": 1.9, - "E53": 1.9, - "Z60": 1.8, - "G20": 1.8, - "R55": 1.8, - "S22": 1.8, - "K59": 1.8, - "N17": 1.8, - "L89": 1.7, - "Z22": 1.7, - "B95": 1.7, - "L97": 1.6, - "R44": 1.6, - "K26": 1.6, - "I95": 1.6, - "N19": 1.6, - "A41": 1.6, - "Z87": 1.5, - "J96": 1.5, - "X59": 1.5, - "M19": 1.5, - "G40": 1.5, - "M81": 1.4, - "S72": 1.4, - "S32": 1.4, - "E16": 1.4, - "R94": 1.4, - "N18": 1.4, - "R33": 1.3, - "R69": 1.3, - "N28": 1.3, - "R32": 1.2, - "G31": 1.2, - "Y95": 1.2, - "S09": 1.2, - "R45": 1.2, - "G45": 1.2, - "Z74": 1.1, - "M79": 1.1, - "W06": 1.1, - "S01": 1.1, - "A04": 1.1, - "A09": 1.1, - "J18": 1.1, - "J69": 1.0, - "R47": 1.0, - "E55": 1.0, - "Z93": 1.0, - "R02": 1.0, - "R63": 0.9, - "H91": 0.9, - "W10": 0.9, - "W01": 0.9, - "E05": 0.9, - "M41": 0.9, - "R13": 0.8, - "Z99": 0.8, - "U80": 0.8, - "M80": 0.8, - "K92": 0.8, - "I63": 0.8, - "N20": 0.7, - "F10": 0.7, - "Y84": 0.7, - "R00": 0.7, - "J22": 0.7, - "Z73": 0.6, - "R79": 0.6, - "Z91": 0.5, - "S51": 0.5, - "F32": 0.5, - "M48": 0.5, - "E83": 0.4, - "M15": 0.4, - "D64": 0.4, - "L08": 0.4, - "R11": 0.3, - "K52": 0.3, - "R50": 0.1, -} - - -def _read_labels(path: Path) -> list[dict[str, str | int]]: - rows: list[dict[str, str | int]] = [] - with path.open(encoding="utf-8") as f: - for i, line in enumerate(f): - line = line.strip() - if not line: - continue - parts = line.split(maxsplit=1) - code = parts[0].strip().upper() - name = parts[1].strip() if len(parts) > 1 else "" - rows.append({"token_id": i + 3, "label_code": code, "label_name": name}) - return rows - - -def main() -> None: - labels = _read_labels(LABELS) - label_codes = {str(row["label_code"]) for row in labels} - missing = sorted(set(UK_HFRS_WEIGHTS) - label_codes) - - rows = [] - for row in labels: - code = str(row["label_code"]) - weight = float(UK_HFRS_WEIGHTS.get(code, 0.0)) - rows.append( - { - **row, - "hfrs_dimension_id": "hfrs_weighted_disease_expression", - "hfrs_dimension": "DeepHealth HFRS-weighted disease expression", - "hfrs_key_area": "UK-HFRS", - "hfrs_weight": weight, - "hfrs_source": ( - "Gilbert et al. Lancet 2018 supplementary appendix Table A2" - ), - "match_source": "exact_three_character_icd10" if weight else "not_in_hfrs", - } - ) - - fieldnames = [ - "token_id", - "label_code", - "label_name", - "hfrs_dimension_id", - "hfrs_dimension", - "hfrs_key_area", - "hfrs_weight", - "hfrs_source", - "match_source", - ] - with OUT.open("w", newline="", encoding="utf-8-sig") as f: - writer = csv.DictWriter(f, fieldnames=fieldnames) - writer.writeheader() - writer.writerows(rows) - - with MISSING_OUT.open("w", newline="", encoding="utf-8-sig") as f: - writer = csv.DictWriter( - f, - fieldnames=[ - "hfrs_source_code", - "hfrs_weight", - "missing_reason", - "hfrs_source", - ], - ) - writer.writeheader() - for code in missing: - writer.writerow( - { - "hfrs_source_code": code, - "hfrs_weight": UK_HFRS_WEIGHTS[code], - "missing_reason": "not_present_in_labels_csv", - "hfrs_source": ( - "Gilbert et al. Lancet 2018 supplementary appendix Table A2" - ), - } - ) - - nonzero = sum(1 for row in rows if float(row["hfrs_weight"]) != 0.0) - print(f"labels: {len(rows)}") - print(f"uk_hfrs_codes: {len(UK_HFRS_WEIGHTS)}") - print(f"matched_nonzero_labels: {nonzero}") - print(f"missing_hfrs_codes: {len(missing)}") - print(f"output: {OUT}") - print(f"missing_output: {MISSING_OUT}") - - -if __name__ == "__main__": - main() diff --git a/burden_index.py b/burden_index.py deleted file mode 100644 index a042009..0000000 --- a/burden_index.py +++ /dev/null @@ -1,407 +0,0 @@ -from __future__ import annotations - -from dataclasses import dataclass -from pathlib import Path -from typing import Any, Sequence - -import numpy as np -import torch -import torch.nn.functional as F - -from eval_data import load_sequence_eval_dataset -from evaluate_auc_v2 import ( - build_model_from_dataset, - load_checkpoint_state_dict, - load_json_config, - load_model_state, - resolve_dist_mode_for_checkpoint, - validate_dataset_metadata, -) -from targets import CHECKUP_IDX, NO_EVENT_IDX, PAD_IDX - - -@dataclass(frozen=True) -class DeepHealthContext: - model: torch.nn.Module - dataset: Any - cfg: dict[str, Any] - dist_mode: str - device: torch.device - run_path: Path - - -@dataclass(frozen=True) -class DiseaseExpressionResult: - disease_ids: np.ndarray - expression: np.ndarray - t_query: float - - -@dataclass(frozen=True) -class OrganInvolvementResult: - organ_ids: list[str] - involvement: np.ndarray - disease_ids: np.ndarray - expression: np.ndarray - t_query: float - - -@dataclass(frozen=True) -class FrailtyRiskResult: - frailty_risk_index: float - disease_ids: np.ndarray - expression: np.ndarray - weights: np.ndarray - t_query: float - - -def load_deephealth_context( - run_path: str | Path, - *, - device: str | torch.device | None = None, -) -> DeepHealthContext: - run_path = Path(run_path) - config_path = run_path / "train_config.json" - model_ckpt_path = run_path / "best_model.pt" - if not config_path.exists(): - raise FileNotFoundError(f"train_config.json not found in {run_path}") - if not model_ckpt_path.exists(): - raise FileNotFoundError(f"best_model.pt not found in {run_path}") - - cfg = load_json_config(config_path) - model_target_mode = str(cfg.get("model_target_mode", "next_token")).lower() - if model_target_mode == "next_token": - raise RuntimeError( - "Disease expression indices require an all_future checkpoint because " - "they use p_d(h, Delta). The provided run is model_target_mode='next_token'." - ) - if model_target_mode != "all_future": - raise ValueError( - "train_config.json model_target_mode must be all_future, got " - f"{model_target_mode!r}." - ) - - device_obj = torch.device( - device if device is not None else ("cuda" if torch.cuda.is_available() else "cpu") - ) - if device_obj.type == "cuda" and not torch.cuda.is_available(): - raise RuntimeError(f"Requested device {device_obj}, but CUDA is not available.") - - dataset = load_sequence_eval_dataset( - model_target_mode="all_future", - data_prefix=cfg.get("data_prefix", "ukb"), - labels_file=cfg.get("labels_file", "labels.csv"), - no_event_interval_years=float(cfg.get("no_event_interval_years", 5.0)), - include_no_event_in_uts_target=bool( - cfg.get("include_no_event_in_uts_target", False) - ), - min_history_events=int(cfg.get("all_future_min_history_events", 1)), - min_future_events=int(cfg.get("all_future_min_future_events", 1)), - extra_info_types=cfg.get("extra_info_types", None), - ) - validate_dataset_metadata(dataset, cfg) - - state_dict = load_checkpoint_state_dict(model_ckpt_path, map_location="cpu") - dist_mode = resolve_dist_mode_for_checkpoint( - str(cfg.get("dist_mode", "exponential")), - state_dict, - ) - if dist_mode not in {"exponential", "weibull", "mixed"}: - raise ValueError(f"Unsupported dist_mode={dist_mode!r}") - - cfg_model = dict(cfg) - cfg_model["dist_mode"] = dist_mode - model = build_model_from_dataset(_ConfigNamespace(), cfg_model, dataset) - load_model_state(model, state_dict) - model.eval().to(device_obj) - - return DeepHealthContext( - model=model, - dataset=dataset, - cfg=cfg, - dist_mode=dist_mode, - device=device_obj, - run_path=run_path, - ) - - -@torch.inference_mode() -def compute_disease_expression( - *, - run_path: str | Path, - disease_ids: Sequence[int] | np.ndarray, - event_seq: Sequence[int] | np.ndarray, - time_seq: Sequence[float] | np.ndarray, - sex: int, - other_type: Sequence[int] | np.ndarray, - other_value: Sequence[float] | np.ndarray, - other_value_kind: Sequence[int] | np.ndarray, - other_time: Sequence[float] | np.ndarray, - t_query: float, - device: str | torch.device | None = None, - context: DeepHealthContext | None = None, -) -> DiseaseExpressionResult: - ctx = context or load_deephealth_context(run_path, device=device) - disease_ids_arr = np.asarray(disease_ids, dtype=np.int64) - expression = model_implied_disease_expression( - ctx=ctx, - disease_ids=disease_ids_arr, - event_seq=event_seq, - time_seq=time_seq, - sex=sex, - other_type=other_type, - other_value=other_value, - other_value_kind=other_value_kind, - other_time=other_time, - t_query=float(t_query), - ) - return DiseaseExpressionResult( - disease_ids=disease_ids_arr.copy(), - expression=expression, - t_query=float(t_query), - ) - - -def compute_organ_involvement_from_expression( - *, - expression: Sequence[float] | np.ndarray, - organ_matrix: np.ndarray, -) -> np.ndarray: - z = np.asarray(expression, dtype=np.float64) - A = np.asarray(organ_matrix, dtype=np.float64) - if A.ndim != 2: - raise ValueError(f"organ_matrix must be 2D, got shape {A.shape}") - if z.ndim != 1 or A.shape[1] != z.size: - raise ValueError( - "expression must be 1D and match organ_matrix columns, got " - f"{z.shape} and {A.shape}" - ) - intensity = -np.log1p(-np.clip(z, 0.0, 1.0 - 1e-7)) - return -np.expm1(-(A @ intensity)) - - -def compute_frailty_risk_from_expression( - *, - expression: Sequence[float] | np.ndarray, - hfrs_weights: Sequence[float] | np.ndarray, -) -> float: - z = np.asarray(expression, dtype=np.float64) - w = np.asarray(hfrs_weights, dtype=np.float64) - if z.shape != w.shape: - raise ValueError(f"expression and hfrs_weights shape mismatch: {z.shape} vs {w.shape}") - return float(np.dot(w, z)) - - -@torch.inference_mode() -def model_implied_disease_expression( - *, - ctx: DeepHealthContext, - disease_ids: np.ndarray, - event_seq: Sequence[int] | np.ndarray, - time_seq: Sequence[float] | np.ndarray, - sex: int, - other_type: Sequence[int] | np.ndarray, - other_value: Sequence[float] | np.ndarray, - other_value_kind: Sequence[int] | np.ndarray, - other_time: Sequence[float] | np.ndarray, - t_query: float, -) -> np.ndarray: - disease_ids = np.asarray(disease_ids, dtype=np.int64) - _validate_disease_ids(ctx, disease_ids) - event_seq_arr, time_seq_arr = _validate_event_inputs(event_seq, time_seq) - other_type_arr, other_value_arr, other_value_kind_arr, other_time_arr = ( - _validate_other_inputs(other_type, other_value, other_value_kind, other_time) - ) - grid = build_readout_grid( - event_seq=event_seq_arr, - time_seq=time_seq_arr, - other_type=other_type_arr, - other_time=other_time_arr, - t_query=float(t_query), - ) - if grid.size == 0: - return np.zeros(disease_ids.size, dtype=np.float64) - - end_times = np.concatenate([grid[1:], np.asarray([t_query], dtype=np.float32)]) - deltas = np.maximum(end_times - grid, 0.0).astype(np.float32) - valid = deltas > 0 - if not np.any(valid): - return np.zeros(disease_ids.size, dtype=np.float64) - - hidden = query_hidden( - ctx=ctx, - event_seq=event_seq_arr, - time_seq=time_seq_arr, - sex=sex, - other_type=other_type_arr, - other_value=other_value_arr, - other_value_kind=other_value_kind_arr, - other_time=other_time_arr, - query_times=grid[valid].astype(np.float32), - ) - interval_prob = probabilities_from_hidden( - ctx=ctx, - hidden=hidden, - disease_ids=disease_ids, - deltas=deltas[valid], - ) - survival = np.prod(1.0 - np.clip(interval_prob, 0.0, 1.0), axis=0) - return (1.0 - survival).astype(np.float64, copy=False) - - -def build_readout_grid( - *, - event_seq: np.ndarray, - time_seq: np.ndarray, - other_type: np.ndarray, - other_time: np.ndarray, - t_query: float, -) -> np.ndarray: - event_mask = (event_seq > PAD_IDX) & (time_seq <= np.float32(t_query)) - other_mask = (other_type > 0) & (other_time <= np.float32(t_query)) - times = np.concatenate( - [ - time_seq[event_mask].astype(np.float32, copy=False), - other_time[other_mask].astype(np.float32, copy=False), - ] - ) - if times.size == 0: - return np.zeros(0, dtype=np.float32) - return np.unique(times) - - -@torch.inference_mode() -def query_hidden( - *, - ctx: DeepHealthContext, - event_seq: np.ndarray, - time_seq: np.ndarray, - sex: int, - other_type: np.ndarray, - other_value: np.ndarray, - other_value_kind: np.ndarray, - other_time: np.ndarray, - query_times: np.ndarray, -) -> torch.Tensor: - if query_times.ndim != 1: - raise ValueError("query_times must be 1D.") - batch_size = int(query_times.size) - if batch_size == 0: - return torch.empty(0, ctx.model.n_embd, device=ctx.device) - - event = torch.from_numpy(event_seq[None, :].repeat(batch_size, axis=0)).long() - times = torch.from_numpy(time_seq[None, :].repeat(batch_size, axis=0)).float() - other_t = torch.from_numpy(other_type[None, :].repeat(batch_size, axis=0)).long() - other_v = torch.from_numpy(other_value[None, :].repeat(batch_size, axis=0)).float() - other_k = torch.from_numpy( - other_value_kind[None, :].repeat(batch_size, axis=0) - ).long() - other_tm = torch.from_numpy(other_time[None, :].repeat(batch_size, axis=0)).float() - sex_t = torch.full((batch_size,), int(sex), dtype=torch.long) - tq = torch.from_numpy(query_times.astype(np.float32, copy=False)).float() - - event = event.to(ctx.device) - return ctx.model( - event_seq=event, - time_seq=times.to(ctx.device), - sex=sex_t.to(ctx.device), - padding_mask=event > PAD_IDX, - t_query=tq.to(ctx.device), - other_type=other_t.to(ctx.device), - other_value=other_v.to(ctx.device), - other_value_kind=other_k.to(ctx.device), - other_time=other_tm.to(ctx.device), - target_mode="all_future", - ) - - -@torch.inference_mode() -def probabilities_from_hidden( - *, - ctx: DeepHealthContext, - hidden: torch.Tensor, - disease_ids: np.ndarray, - deltas: np.ndarray, -) -> np.ndarray: - if hidden.ndim != 2: - raise ValueError(f"hidden must have shape (N, H), got {tuple(hidden.shape)}") - if deltas.ndim != 1 or deltas.size != hidden.shape[0]: - raise ValueError( - "deltas must be 1D with the same length as hidden rows, got " - f"{deltas.shape} vs {tuple(hidden.shape)}" - ) - ids = torch.as_tensor(disease_ids, dtype=torch.long, device=ctx.device) - logits = ctx.model.calc_risk(hidden)[:, ids] - rate = F.softplus(logits).clamp_min(1e-8) - delta_t = torch.as_tensor(deltas, dtype=rate.dtype, device=ctx.device).clamp_min(0) - - if ctx.dist_mode == "weibull": - rho = ctx.model.calc_weibull_rho(hidden)[:, ids] - exposure = torch.pow(delta_t[:, None], rho) - elif ctx.dist_mode == "mixed": - exposure = delta_t[:, None].expand_as(rate) - death_idx = int(getattr(ctx.model, "death_idx", getattr(ctx.model, "vocab_size", 0) - 1)) - death_cols = [j for j, token in enumerate(disease_ids.tolist()) if int(token) == death_idx] - if death_cols: - death_rho = ctx.model.calc_death_rho(hidden) - for col in death_cols: - exposure[:, int(col)] = torch.pow(delta_t, death_rho) - else: - exposure = delta_t[:, None].expand_as(rate) - - prob = -torch.expm1(-rate * exposure) - return prob.detach().cpu().numpy().astype(np.float64, copy=False) - - -class _ConfigNamespace: - def __getattr__(self, _name: str) -> None: - return None - - -def _validate_disease_ids(ctx: DeepHealthContext, disease_ids: np.ndarray) -> None: - if disease_ids.ndim != 1 or disease_ids.size == 0: - raise ValueError("disease_ids must be a non-empty 1D array.") - vocab_size = int(getattr(ctx.model, "vocab_size", ctx.model.risk_head.out_features)) - if np.any(disease_ids < 0) or np.any(disease_ids >= vocab_size): - raise ValueError(f"disease_ids must be in [0, {vocab_size}), got {disease_ids}") - - -def _validate_event_inputs( - event_seq: Sequence[int] | np.ndarray, - time_seq: Sequence[float] | np.ndarray, -) -> tuple[np.ndarray, np.ndarray]: - events = np.asarray(event_seq, dtype=np.int64) - times = np.asarray(time_seq, dtype=np.float32) - if events.ndim != 1 or times.ndim != 1: - raise ValueError("event_seq and time_seq must be 1D.") - if events.shape != times.shape: - raise ValueError( - f"event_seq and time_seq must have the same shape, got {events.shape} vs {times.shape}" - ) - if events.size == 0: - raise ValueError("event_seq must contain at least one token.") - if not np.all(np.isfinite(times)): - raise ValueError("time_seq contains non-finite values.") - return events, times - - -def _validate_other_inputs( - other_type: Sequence[int] | np.ndarray, - other_value: Sequence[float] | np.ndarray, - other_value_kind: Sequence[int] | np.ndarray, - other_time: Sequence[float] | np.ndarray, -) -> tuple[np.ndarray, np.ndarray, np.ndarray, np.ndarray]: - typ = np.asarray(other_type, dtype=np.int64) - val = np.asarray(other_value, dtype=np.float32) - kind = np.asarray(other_value_kind, dtype=np.int64) - tm = np.asarray(other_time, dtype=np.float32) - if not (typ.shape == val.shape == kind.shape == tm.shape): - raise ValueError( - "other_type, other_value, other_value_kind, and other_time must " - f"have the same shape, got {typ.shape}, {val.shape}, {kind.shape}, {tm.shape}." - ) - if typ.ndim != 1: - raise ValueError("other_* inputs must be 1D.") - if not np.all(np.isfinite(tm)): - raise ValueError("other_time contains non-finite values.") - return typ, val, kind, tm diff --git a/burden_index_method.tex b/burden_index_method.tex deleted file mode 100644 index 6470276..0000000 --- a/burden_index_method.tex +++ /dev/null @@ -1,161 +0,0 @@ -\documentclass[11pt]{article} - -\usepackage[margin=1in]{geometry} -\usepackage{amsmath, amssymb} -\usepackage{booktabs} -\usepackage{enumitem} -\usepackage{hyperref} - -\title{DeepHealth Disease Expression, Organ Involvement, and Frailty Risk Indices} -\author{} -\date{} - -\begin{document} - -\maketitle - -\begin{abstract} -DeepHealth provides a query-time hidden state \(h(t)\) and disease-specific -risk functions \(p_d(h,\Delta)\). We use these outputs to define a continuous -disease expression rate \(z_d(t)\). This quantity should be interpreted as how -much disease \(d\) is model-implied to have formed or expressed by query time -\(t\), not as true physiological damage. Based on \(z_d(t)\), we define two -downstream indices: an organ involvement index, which summarizes whether an -organ-age-inspired clinical system is involved by any related disease process, -and a DeepHealth-HFRS frailty risk index, which is the original UK-HFRS weighted -sum with binary disease occurrence replaced by continuous disease expression. -\end{abstract} - -\section{Disease Expression Rate} - -For a patient queried at time \(t\), let the historical readout times be -\[ - t_0 < t_1 < \cdots < t_n \le t,\qquad t_{n+1}=t. -\] -For each interval \([t_i,t_{i+1}]\), DeepHealth produces a hidden state -\(h_i=h(t_i)\) and an interval risk -\[ - q_{d,i}(t)=p_d(h_i,t_{i+1}-t_i). -\] -The model-implied disease expression rate is defined by noisy-or accumulation: -\[ - z_d(t) - = - 1-\prod_{i=0}^{n}\left[1-q_{d,i}(t)\right]. -\] -Informally, \(z_d(t)\) is the degree to which disease \(d\) is expressed in the -patient by time \(t\). Unlike a raw diagnosis indicator, it is continuous and -can reflect heterogeneity within the same ICD label. - -\section{Organ Involvement Index} - -The organ index is not a frailty score, health reserve score, or organ age. It -is an organ involvement index. Let \(\mathcal{D}_k\) be the set of diseases -assigned to organ/system \(k\). Define disease expression intensity as -\[ - \Lambda_d(t)=-\log\left[1-z_d(t)\right]. -\] -The equal-weight organ involvement index is -\[ - O_k(t) - = - 1-\exp\left( - -\sum_{d\in\mathcal{D}_k}\Lambda_d(t) - \right). -\] -Equivalently, -\[ - O_k(t) - = - 1- - \prod_{d\in\mathcal{D}_k} - \left[1-z_d(t)\right]. -\] -Thus \(O_k(t)\in[0,1]\) is the probability-like degree to which organ/system -\(k\) is involved by at least one related disease process. In the current -version all diseases assigned to the same organ are equally weighted; this is a -first-stage structural definition. Future versions can introduce -organ-specific disease weights \(\alpha_{k,d}\): -\[ - O_k(t) - = - 1-\exp\left( - -\sum_{d\in\mathcal{D}_k}\alpha_{k,d}\Lambda_d(t) - \right). -\] - -\section{Organ List} - -The organ/system categories are inspired by organ-age studies, especially -organ-specific plasma proteomic aging models, and are adapted to ICD disease -labels. The current list is: -\begin{center} -\begin{tabular}{ll} -\toprule -ID & Label \\ -\midrule -brain\_neurologic & Brain and neurologic system \\ -heart & Heart \\ -artery\_vascular & Artery and vascular system \\ -immune & Immune and infection-related system \\ -intestine\_digestive & Intestine and digestive system \\ -kidney & Kidney and urinary system \\ -liver & Liver \\ -lung & Lung and respiratory system \\ -muscle\_musculoskeletal & Muscle and musculoskeletal system \\ -pancreas\_endocrine & Pancreas and endocrine system \\ -adipose\_metabolic & Adipose and metabolic system \\ -female\_reproductive & Female reproductive system \\ -male\_reproductive & Male reproductive system \\ -neoplasm & Neoplasm \\ -\bottomrule -\end{tabular} -\end{center} -The neoplasm category is retained as a disease-system category rather than -forced into a single anatomical organ. Sex-specific reproductive diseases are -separated into female and male reproductive systems. - -\section{DeepHealth-HFRS Frailty Risk Index} - -The original UK-HFRS is a weighted sum over binary disease occurrence: -\[ - \operatorname{HFRS}^{\mathrm{obs}}(t) - = - \sum_{d\in\mathcal{D}_{\mathrm{HFRS}}} - w^{\mathrm{HFRS}}_d\,o_d(t), - \qquad - o_d(t)\in\{0,1\}. -\] -DeepHealth-HFRS keeps the published UK-HFRS weights and replaces the binary -disease state with the continuous DeepHealth disease expression rate: -\[ - \operatorname{HFRS}^{\mathrm{DH}}(t) - = - \sum_{d\in\mathcal{D}_{\mathrm{HFRS}}} - w^{\mathrm{HFRS}}_d\,z_d(t), - \qquad - z_d(t)\in[0,1]. -\] -This is a natural continuous extension of the original HFRS, so it can still be -called a frailty risk index. The semantic change is not the HFRS weight system; -the change is the disease state variable. - -\section{Current Implementation} - -The current code computes historical current-state indices only. No future -horizon is used. For each landmark age \(t\), it outputs: -\begin{itemize}[leftmargin=*] - \item \(z_d(t)\) internally as model-implied disease expression; - \item \(O_k(t)\) as equal-weight organ involvement; - \item \(\operatorname{HFRS}^{\mathrm{DH}}(t)\) as DeepHealth-HFRS frailty - risk. -\end{itemize} -The output table uses the columns -\[ - \texttt{index\_type},\quad - \texttt{index\_id},\quad - \texttt{index\_label},\quad - \texttt{index\_value}. -\] - -\end{document} diff --git a/burden_index_method_zh.tex b/burden_index_method_zh.tex deleted file mode 100644 index ff29975..0000000 --- a/burden_index_method_zh.tex +++ /dev/null @@ -1,142 +0,0 @@ -\documentclass[11pt]{ctexart} - -\usepackage[margin=1in]{geometry} -\usepackage{amsmath, amssymb} -\usepackage{booktabs} -\usepackage{enumitem} -\usepackage{hyperref} - -\title{DeepHealth 疾病表达率、器官受累指数与衰弱风险指数} -\author{} -\date{} - -\begin{document} - -\maketitle - -\begin{abstract} -DeepHealth 在查询时刻 \(t\) 输出隐含状态 \(h(t)\),并给出疾病风险函数 -\(p_d(h,\Delta)\)。我们首先定义连续的疾病表达率 \(z_d(t)\):它表示模型认为疾病 \(d\) -截至 \(t\) 在该个体身上形成或表达了多少,而不是疾病造成的真实损害。基于 \(z_d(t)\), -本文定义两类指数:器官受累指数和 DeepHealth-HFRS 衰弱风险指数。前者表示器官/系统是否被相关疾病过程累及; -后者是原版 UK-HFRS 的自然连续化,即用连续疾病表达率替代二值疾病发生状态。 -\end{abstract} - -\section{疾病表达率} - -设历史 readout 时间为 -\[ - t_0 < t_1 < \cdots < t_n \le t,\qquad t_{n+1}=t. -\] -在区间 \([t_i,t_{i+1}]\) 上,模型给出疾病 \(d\) 的区间风险 -\[ - q_{d,i}(t)=p_d(h(t_i),t_{i+1}-t_i). -\] -疾病表达率定义为 -\[ - z_d(t) - = - 1-\prod_{i=0}^{n}\left[1-q_{d,i}(t)\right]. -\] -直观上,\(z_d(t)\) 表示“这个病在该个体身上形成或表达了多少”。它不是二值诊断记录, -因此可以表达同一 ICD 标签下的个体异质性。 - -\section{器官受累指数} - -器官指数不定义为器官年龄、器官健康储备或器官衰弱,而定义为器官受累指数。设 \(\mathcal{D}_k\) -是归属于器官/系统 \(k\) 的疾病集合。定义疾病表达强度 -\[ - \Lambda_d(t)=-\log\left[1-z_d(t)\right]. -\] -当前版本使用等权器官受累定义: -\[ - O_k(t) - = - 1-\exp\left( - -\sum_{d\in\mathcal{D}_k}\Lambda_d(t) - \right), -\] -等价于 -\[ - O_k(t) - = - 1- - \prod_{d\in\mathcal{D}_k} - \left[1-z_d(t)\right]. -\] -因此 \(O_k(t)\in[0,1]\),表示器官/系统 \(k\) 被至少一个相关疾病过程累及的概率型程度。 -当前所有疾病在同一器官内等权;后续可扩展为带疾病权重的形式: -\[ - O_k(t) - = - 1-\exp\left( - -\sum_{d\in\mathcal{D}_k}\alpha_{k,d}\Lambda_d(t) - \right). -\] - -\section{器官列表} - -当前器官/系统列表参考器官年龄研究中的 organ-age-inspired systems,并结合 ICD 疾病标签空间调整: -\begin{center} -\begin{tabular}{ll} -\toprule -ID & 含义 \\ -\midrule -brain\_neurologic & 脑与神经系统 \\ -heart & 心脏 \\ -artery\_vascular & 动脉与血管系统 \\ -immune & 免疫与感染相关系统 \\ -intestine\_digestive & 肠道与消化系统 \\ -kidney & 肾脏与泌尿系统 \\ -liver & 肝脏 \\ -lung & 肺与呼吸系统 \\ -muscle\_musculoskeletal & 肌肉骨骼系统 \\ -pancreas\_endocrine & 胰腺与内分泌系统 \\ -adipose\_metabolic & 脂肪与代谢系统 \\ -female\_reproductive & 女性生殖系统 \\ -male\_reproductive & 男性生殖系统 \\ -neoplasm & 肿瘤 \\ -\bottomrule -\end{tabular} -\end{center} -肿瘤作为疾病系统单独保留,不强行归入某个单一器官。男女生殖系统单独拆分。 - -\section{DeepHealth-HFRS 衰弱风险指数} - -原版 UK-HFRS 是二值疾病发生状态的加权和: -\[ - \operatorname{HFRS}^{\mathrm{obs}}(t) - = - \sum_{d\in\mathcal{D}_{\mathrm{HFRS}}} - w^{\mathrm{HFRS}}_d o_d(t), - \qquad - o_d(t)\in\{0,1\}. -\] -DeepHealth-HFRS 保留原版 UK-HFRS 权重,只把疾病状态从二值观测替换为连续疾病表达率: -\[ - \operatorname{HFRS}^{\mathrm{DH}}(t) - = - \sum_{d\in\mathcal{D}_{\mathrm{HFRS}}} - w^{\mathrm{HFRS}}_d z_d(t), - \qquad - z_d(t)\in[0,1]. -\] -因此 DeepHealth-HFRS 仍然可以称为衰弱风险指数;它是原版 HFRS 的自然连续化。 - -\section{当前实现} - -当前代码只计算历史当前状态,不再使用未来 horizon。每个 landmark age \(t\) 输出: -\begin{itemize}[leftmargin=*] - \item 内部疾病表达率 \(z_d(t)\); - \item 等权器官受累指数 \(O_k(t)\); - \item DeepHealth-HFRS 衰弱风险指数 \(\operatorname{HFRS}^{\mathrm{DH}}(t)\)。 -\end{itemize} -输出表使用 -\[ - \texttt{index\_type},\quad - \texttt{index\_id},\quad - \texttt{index\_label},\quad - \texttt{index\_value}. -\] - -\end{document} diff --git a/compute_deephealth_indices_landmarks.py b/compute_deephealth_indices_landmarks.py deleted file mode 100644 index d5657d7..0000000 --- a/compute_deephealth_indices_landmarks.py +++ /dev/null @@ -1,717 +0,0 @@ -from __future__ import annotations - -import argparse -import multiprocessing as mp -import time -from concurrent.futures import ProcessPoolExecutor, as_completed -from pathlib import Path -from typing import Any, Iterable - -import numpy as np -import pandas as pd -import torch -from torch.nn.utils.rnn import pad_sequence -from torch.utils.data import DataLoader, IterableDataset, get_worker_info -from tqdm.auto import tqdm - -from burden_index import ( - build_readout_grid, - load_deephealth_context, - probabilities_from_hidden, -) -from evaluate_auc_v2 import make_eval_indices, parse_float_list -from targets import CHECKUP_IDX, NO_EVENT_IDX, PAD_IDX - - -def _parse_landmark_ages(args: argparse.Namespace) -> np.ndarray: - explicit = parse_float_list(args.landmark_ages) - if explicit: - ages = np.asarray(explicit, dtype=np.float32) - else: - ages = np.arange( - float(args.landmark_start), - float(args.landmark_stop) + 1e-6, - float(args.landmark_step), - dtype=np.float32, - ) - if ages.size == 0: - raise ValueError("No landmark ages were provided.") - return ages - - -def _parse_devices(args: argparse.Namespace) -> list[str | None]: - if args.devices is not None and str(args.devices).strip(): - devices = [x.strip() for x in str(args.devices).split(",") if x.strip()] - if not devices: - raise ValueError("--devices was provided but no devices were parsed.") - return devices - return [args.device] - - -def _load_index_matrices( - *, - organ_mapping_csv: Path, - hfrs_mapping_csv: Path, -) -> tuple[np.ndarray, list[dict[str, Any]], dict[str, Any]]: - organ_df = pd.read_csv(organ_mapping_csv) - organ_required = {"token_id", "organ_id", "organ_label", "organ_weight"} - missing = sorted(organ_required - set(organ_df.columns)) - if missing: - raise ValueError(f"{organ_mapping_csv} is missing required columns: {missing}") - organ_df = organ_df.copy() - organ_df["token_id"] = pd.to_numeric(organ_df["token_id"], errors="raise").astype(int) - organ_df["organ_weight"] = pd.to_numeric( - organ_df["organ_weight"], errors="raise" - ).astype(float) - organ_df = organ_df[(organ_df["organ_id"].astype(str) != "") & (organ_df["organ_weight"] > 0)] - if organ_df.empty: - raise ValueError(f"{organ_mapping_csv} has no mapped organ rows.") - - hfrs_df = pd.read_csv(hfrs_mapping_csv) - hfrs_required = {"token_id", "hfrs_weight"} - missing = sorted(hfrs_required - set(hfrs_df.columns)) - if missing: - raise ValueError(f"{hfrs_mapping_csv} is missing required columns: {missing}") - hfrs_df = hfrs_df.copy() - hfrs_df["token_id"] = pd.to_numeric(hfrs_df["token_id"], errors="raise").astype(int) - hfrs_df["hfrs_weight"] = pd.to_numeric( - hfrs_df["hfrs_weight"], errors="raise" - ).astype(float) - hfrs_df = hfrs_df[hfrs_df["hfrs_weight"] > 0] - if hfrs_df.empty: - raise ValueError(f"{hfrs_mapping_csv} has no non-zero HFRS weights.") - - union_disease_ids = np.asarray( - sorted( - set(organ_df["token_id"].astype(int).tolist()) - | set(hfrs_df["token_id"].astype(int).tolist()) - ), - dtype=np.int64, - ) - union_pos = {int(token): i for i, token in enumerate(union_disease_ids.tolist())} - - organ_ids = sorted(organ_df["organ_id"].astype(str).unique().tolist()) - organ_pos = {organ_id: i for i, organ_id in enumerate(organ_ids)} - organ_matrix = np.zeros((len(organ_ids), union_disease_ids.size), dtype=np.float32) - organ_meta_by_id = {} - for _, row in organ_df.iterrows(): - organ_id = str(row["organ_id"]) - token = int(row["token_id"]) - organ_matrix[organ_pos[organ_id], union_pos[token]] = 1.0 - organ_meta_by_id.setdefault( - organ_id, - { - "index_type": "organ_involvement", - "index_id": organ_id, - "index_label": str(row["organ_label"]), - }, - ) - organ_meta = [organ_meta_by_id[organ_id] for organ_id in organ_ids] - - hfrs_weights = np.zeros(union_disease_ids.size, dtype=np.float32) - for _, row in hfrs_df.iterrows(): - hfrs_weights[union_pos[int(row["token_id"])]] = float(row["hfrs_weight"]) - hfrs_meta = { - "index_type": "frailty_risk", - "index_id": "deephealth_hfrs", - "index_label": "DeepHealth-HFRS frailty risk index", - } - - matrices = [ - { - "kind": "organ_involvement", - "matrix": organ_matrix, - "meta": organ_meta, - }, - { - "kind": "frailty_risk", - "weights": hfrs_weights, - "meta": hfrs_meta, - }, - ] - return union_disease_ids, matrices, { - "organ_mapped_tokens": int(organ_df["token_id"].nunique()), - "hfrs_mapped_tokens": int(hfrs_df["token_id"].nunique()), - } - - -def _config_split_indices( - n: int, - cfg: dict[str, Any], - eval_split: str, - subset_size: int, -) -> np.ndarray: - args = argparse.Namespace( - train_ratio=None, - val_ratio=None, - test_ratio=None, - seed=None, - eval_split=eval_split, - dataset_subset_size=subset_size if subset_size > 0 else None, - ) - - class _Sized: - def __len__(self) -> int: - return n - - return make_eval_indices(_Sized(), args, cfg) - - -def _eligible_landmark_rows( - dataset: Any, - subset_indices: np.ndarray, - landmark_ages: np.ndarray, - *, - min_history_events: int, -) -> list[dict[str, Any]]: - rows: list[dict[str, Any]] = [] - special = np.asarray([PAD_IDX, CHECKUP_IDX, NO_EVENT_IDX], dtype=np.int64) - for patient_id, dataset_index in enumerate(subset_indices.tolist()): - sample = dataset.samples[int(dataset_index)] - seq_event = np.asarray(sample["event_seq"], dtype=np.int64) - seq_time = np.asarray(sample["time_seq"], dtype=np.float32) - tgt_event = np.asarray(sample["target_event_seq"], dtype=np.int64) - tgt_time = np.asarray(sample["target_time_seq"], dtype=np.float32) - if seq_event.size == 0 or tgt_event.size == 0: - continue - - full_event = np.concatenate([seq_event, tgt_event[-1:]]) - full_time = np.concatenate([seq_time, tgt_time[-1:]]) - followup_end = float(np.max(full_time)) - - for landmark_age in landmark_ages.tolist(): - t_query = np.float32(float(landmark_age)) - if not (followup_end > float(t_query)): - continue - prefix_mask = full_time <= t_query - if not np.any(prefix_mask): - continue - prefix_events = full_event[prefix_mask].astype(np.int64, copy=False) - valid_history = ~np.isin(prefix_events, special) - if int(valid_history.sum()) < int(min_history_events): - continue - rows.append( - { - "patient_id": int(patient_id), - "dataset_index": int(dataset_index), - "sex": int(sample["sex"]), - "landmark_age": t_query, - "t_query": t_query, - "followup_end_time": np.float32(followup_end), - "event_seq": prefix_events, - "time_seq": full_time[prefix_mask].astype(np.float32, copy=False), - "other_type": np.asarray(sample["other_type"], dtype=np.int64), - "other_value": np.asarray(sample["other_value"], dtype=np.float32), - "other_value_kind": np.asarray(sample["other_value_kind"], dtype=np.int64), - "other_time": np.asarray(sample["other_time"], dtype=np.float32), - } - ) - return rows - - -def _row_to_worker_spec(row: dict[str, Any]) -> dict[str, Any]: - return { - "patient_id": int(row["patient_id"]), - "dataset_index": int(row["dataset_index"]), - "landmark_age": float(row["landmark_age"]), - "followup_end_time": float(row["followup_end_time"]), - } - - -def _materialize_worker_rows( - dataset: Any, - row_specs: list[dict[str, Any]], -) -> list[dict[str, Any]]: - rows: list[dict[str, Any]] = [] - for spec in row_specs: - sample = dataset.samples[int(spec["dataset_index"])] - seq_event = np.asarray(sample["event_seq"], dtype=np.int64) - seq_time = np.asarray(sample["time_seq"], dtype=np.float32) - tgt_event = np.asarray(sample["target_event_seq"], dtype=np.int64) - tgt_time = np.asarray(sample["target_time_seq"], dtype=np.float32) - full_event = np.concatenate([seq_event, tgt_event[-1:]]) - full_time = np.concatenate([seq_time, tgt_time[-1:]]) - t_query = np.float32(float(spec["landmark_age"])) - prefix_mask = full_time <= t_query - rows.append( - { - "patient_id": int(spec["patient_id"]), - "dataset_index": int(spec["dataset_index"]), - "sex": int(sample["sex"]), - "landmark_age": t_query, - "t_query": t_query, - "followup_end_time": np.float32(float(spec["followup_end_time"])), - "event_seq": full_event[prefix_mask].astype(np.int64, copy=False), - "time_seq": full_time[prefix_mask].astype(np.float32, copy=False), - "other_type": np.asarray(sample["other_type"], dtype=np.int64), - "other_value": np.asarray(sample["other_value"], dtype=np.float32), - "other_value_kind": np.asarray(sample["other_value_kind"], dtype=np.int64), - "other_time": np.asarray(sample["other_time"], dtype=np.float32), - } - ) - return rows - - -class HistoricalReadoutDataset(IterableDataset): - def __init__(self, rows: list[dict[str, Any]]) -> None: - super().__init__() - self.rows = rows - - def __iter__(self) -> Iterable[dict[str, torch.Tensor]]: - worker = get_worker_info() - if worker is None: - start, step = 0, 1 - else: - start, step = int(worker.id), int(worker.num_workers) - - for row_idx in range(start, len(self.rows), step): - row = self.rows[row_idx] - grid = build_readout_grid( - event_seq=row["event_seq"], - time_seq=row["time_seq"], - other_type=row["other_type"], - other_time=row["other_time"], - t_query=float(row["t_query"]), - ) - if grid.size == 0: - continue - end_times = np.concatenate([grid[1:], np.asarray([row["t_query"]], dtype=np.float32)]) - deltas = np.maximum(end_times - grid, 0.0).astype(np.float32) - valid = deltas > 0 - for query_time, delta in zip(grid[valid].tolist(), deltas[valid].tolist()): - yield _make_readout_job(row, row_idx, query_time, delta) - - -def _make_readout_job( - row: dict[str, Any], - row_idx: int, - query_time: float, - delta: float, -) -> dict[str, torch.Tensor]: - return { - "event_seq": torch.from_numpy(np.asarray(row["event_seq"], dtype=np.int64)).long(), - "time_seq": torch.from_numpy(np.asarray(row["time_seq"], dtype=np.float32)).float(), - "sex": torch.tensor(int(row["sex"]), dtype=torch.long), - "other_type": torch.from_numpy(np.asarray(row["other_type"], dtype=np.int64)).long(), - "other_value": torch.from_numpy(np.asarray(row["other_value"], dtype=np.float32)).float(), - "other_value_kind": torch.from_numpy( - np.asarray(row["other_value_kind"], dtype=np.int64) - ).long(), - "other_time": torch.from_numpy(np.asarray(row["other_time"], dtype=np.float32)).float(), - "query_time": torch.tensor(float(query_time), dtype=torch.float32), - "delta": torch.tensor(float(delta), dtype=torch.float32), - "row_idx": torch.tensor(int(row_idx), dtype=torch.long), - } - - -def _collate_readout_jobs(batch: list[dict[str, torch.Tensor]]) -> dict[str, torch.Tensor]: - event_seq = pad_sequence( - [x["event_seq"] for x in batch], batch_first=True, padding_value=PAD_IDX - ) - return { - "event_seq": event_seq, - "time_seq": pad_sequence( - [x["time_seq"] for x in batch], batch_first=True, padding_value=0.0 - ), - "padding_mask": event_seq > PAD_IDX, - "sex": torch.stack([x["sex"] for x in batch]), - "other_type": pad_sequence( - [x["other_type"] for x in batch], batch_first=True, padding_value=0 - ), - "other_value": pad_sequence( - [x["other_value"] for x in batch], batch_first=True, padding_value=0.0 - ), - "other_value_kind": pad_sequence( - [x["other_value_kind"] for x in batch], batch_first=True, padding_value=0 - ), - "other_time": pad_sequence( - [x["other_time"] for x in batch], batch_first=True, padding_value=0.0 - ), - "query_time": torch.stack([x["query_time"] for x in batch]), - "delta": torch.stack([x["delta"] for x in batch]), - "row_idx": torch.stack([x["row_idx"] for x in batch]), - } - - -@torch.inference_mode() -def _readout_probabilities( - *, - ctx: Any, - batch: dict[str, torch.Tensor], - disease_ids: np.ndarray, -) -> torch.Tensor: - event = batch["event_seq"].long().to(ctx.device, non_blocking=True) - hidden = ctx.model( - event_seq=event, - time_seq=batch["time_seq"].float().to(ctx.device, non_blocking=True), - sex=batch["sex"].long().to(ctx.device, non_blocking=True), - padding_mask=event > PAD_IDX, - t_query=batch["query_time"].float().to(ctx.device, non_blocking=True), - other_type=batch["other_type"].long().to(ctx.device, non_blocking=True), - other_value=batch["other_value"].float().to(ctx.device, non_blocking=True), - other_value_kind=batch["other_value_kind"].long().to(ctx.device, non_blocking=True), - other_time=batch["other_time"].float().to(ctx.device, non_blocking=True), - target_mode="all_future", - ) - deltas = batch["delta"].detach().cpu().numpy().astype(np.float32, copy=False) - prob = probabilities_from_hidden( - ctx=ctx, - hidden=hidden, - disease_ids=disease_ids, - deltas=deltas, - ) - return torch.as_tensor(prob, dtype=torch.float32, device=ctx.device) - - -def _project_rows( - *, - rows: list[dict[str, Any]], - survival_by_row: torch.Tensor, - matrices: list[dict[str, Any]], - ctx: Any, -) -> list[dict[str, Any]]: - disease_expression = 1.0 - survival_by_row.clamp(0.0, 1.0) - disease_intensity = -torch.log(survival_by_row.clamp(1e-7, 1.0)) - out: list[dict[str, Any]] = [] - - organ_matrix = torch.as_tensor( - matrices[0]["matrix"], dtype=torch.float32, device=ctx.device - ) - organ_values = -torch.expm1(-torch.matmul(disease_intensity, organ_matrix.T)) - organ_values_np = organ_values.detach().cpu().numpy() - - hfrs_weights = torch.as_tensor( - matrices[1]["weights"], dtype=torch.float32, device=ctx.device - ) - hfrs_values = torch.matmul(disease_expression, hfrs_weights) - hfrs_values_np = hfrs_values.detach().cpu().numpy() - - for row_idx, row in enumerate(rows): - base = { - "patient_id": row["patient_id"], - "dataset_index": row["dataset_index"], - "sex": row["sex"], - "landmark_age": float(row["landmark_age"]), - "t_query": float(row["t_query"]), - "followup_end_time": float(row["followup_end_time"]), - } - for dim_idx, meta in enumerate(matrices[0]["meta"]): - out.append( - { - **base, - "index_type": meta["index_type"], - "index_id": meta["index_id"], - "index_label": meta["index_label"], - "index_value": float(organ_values_np[row_idx, dim_idx]), - } - ) - out.append( - { - **base, - "index_type": matrices[1]["meta"]["index_type"], - "index_id": matrices[1]["meta"]["index_id"], - "index_label": matrices[1]["meta"]["index_label"], - "index_value": float(hfrs_values_np[row_idx]), - } - ) - return out - - -def _compute_rows( - *, - rows: list[dict[str, Any]], - disease_ids: np.ndarray, - matrices: list[dict[str, Any]], - readout_batch_size: int, - num_workers: int, - ctx: Any, - log_prefix: str, -) -> tuple[list[dict[str, Any]], int, dict[str, float]]: - survival_by_row = torch.ones( - (len(rows), disease_ids.size), dtype=torch.float32, device=ctx.device - ) - loader = DataLoader( - HistoricalReadoutDataset(rows), - batch_size=max(1, int(readout_batch_size)), - collate_fn=_collate_readout_jobs, - num_workers=max(0, int(num_workers)), - pin_memory=ctx.device.type == "cuda", - persistent_workers=int(num_workers) > 0, - prefetch_factor=2 if int(num_workers) > 0 else None, - ) - readout_jobs = 0 - n_batches = 0 - forward_sec = 0.0 - reduce_sec = 0.0 - for batch in loader: - t0 = time.perf_counter() - prob = _readout_probabilities(ctx=ctx, batch=batch, disease_ids=disease_ids) - if ctx.device.type == "cuda": - torch.cuda.synchronize(ctx.device) - forward_sec += time.perf_counter() - t0 - - t1 = time.perf_counter() - row_indices = batch["row_idx"].long().to(ctx.device, non_blocking=True) - interval_survival = 1.0 - prob.clamp(0.0, 1.0) - if hasattr(survival_by_row, "scatter_reduce_"): - survival_by_row.scatter_reduce_( - dim=0, - index=row_indices[:, None].expand_as(interval_survival), - src=interval_survival, - reduce="prod", - include_self=True, - ) - else: - for job_idx in range(interval_survival.shape[0]): - survival_by_row[int(row_indices[job_idx].item())] *= interval_survival[job_idx] - if ctx.device.type == "cuda": - torch.cuda.synchronize(ctx.device) - reduce_sec += time.perf_counter() - t1 - - n_batches += 1 - readout_jobs += int(batch["row_idx"].numel()) - if n_batches == 1 or n_batches % 50 == 0: - print( - f"{log_prefix} processed {readout_jobs} readout jobs in {n_batches} batches", - flush=True, - ) - - t2 = time.perf_counter() - out = _project_rows( - rows=rows, - survival_by_row=survival_by_row, - matrices=matrices, - ctx=ctx, - ) - if ctx.device.type == "cuda": - torch.cuda.synchronize(ctx.device) - reduce_sec += time.perf_counter() - t2 - return out, readout_jobs, {"forward_sec": forward_sec, "reduce_sec": reduce_sec} - - -def _write_rows_csv(rows: list[dict[str, Any]], output_path: Path) -> int: - df = pd.DataFrame(rows) - df.to_csv(output_path, index=False) - return int(len(df)) - - -def _concat_csv_shards(shard_paths: list[Path], output_path: Path) -> None: - wrote_header = False - with output_path.open("w", encoding="utf-8", newline="") as out_f: - for shard_path in shard_paths: - with shard_path.open("r", encoding="utf-8", newline="") as in_f: - header = in_f.readline() - if not wrote_header: - out_f.write(header) - wrote_header = True - for line in in_f: - out_f.write(line) - shard_path.unlink(missing_ok=True) - - -def _estimate_jobs(row: dict[str, Any]) -> int: - grid = build_readout_grid( - event_seq=row["event_seq"], - time_seq=row["time_seq"], - other_type=row["other_type"], - other_time=row["other_time"], - t_query=float(row["t_query"]), - ) - if grid.size == 0: - return 1 - end_times = np.concatenate([grid[1:], np.asarray([row["t_query"]], dtype=np.float32)]) - return max(int(np.sum(np.maximum(end_times - grid, 0.0) > 0)), 1) - - -def _split_rows(rows: list[dict[str, Any]], devices: list[str | None]) -> list[tuple[str | None, list[dict[str, Any]]]]: - if len(devices) <= 1: - return [(devices[0], rows)] - buckets: list[list[dict[str, Any]]] = [[] for _ in devices] - loads = np.zeros(len(devices), dtype=np.int64) - for row in sorted(rows, key=_estimate_jobs, reverse=True): - idx = int(np.argmin(loads)) - buckets[idx].append(row) - loads[idx] += _estimate_jobs(row) - return [(device, bucket) for device, bucket in zip(devices, buckets) if bucket] - - -def _worker(payload: dict[str, Any]) -> dict[str, Any]: - device = payload["device"] - shard_path = Path(payload["shard_path"]) - print(f"[Index worker {device}] starting with {len(payload['row_specs'])} rows", flush=True) - ctx = load_deephealth_context(payload["run_path"], device=device) - rows = _materialize_worker_rows(ctx.dataset, payload["row_specs"]) - out, readout_jobs, timings = _compute_rows( - rows=rows, - disease_ids=payload["disease_ids"], - matrices=payload["matrices"], - readout_batch_size=int(payload["readout_batch_size"]), - num_workers=int(payload["num_workers"]), - ctx=ctx, - log_prefix=f"[Index worker {device}]", - ) - t0 = time.perf_counter() - row_count = _write_rows_csv(out, shard_path) - timings["write_csv_sec"] = time.perf_counter() - t0 - print(f"[Index worker {device}] wrote {row_count} rows to {shard_path}", flush=True) - return { - "shard_path": str(shard_path), - "row_count": row_count, - "readout_jobs": readout_jobs, - "timings": timings, - } - - -def main() -> None: - parser = argparse.ArgumentParser( - description="Compute DeepHealth organ involvement and frailty risk indices." - ) - parser.add_argument("--run_path", type=str, required=True) - parser.add_argument( - "--organ_mapping_csv", - type=str, - default="organ_involvement_label_mapping.csv", - ) - parser.add_argument("--hfrs_mapping_csv", type=str, default="uk_hfrs_label_mapping.csv") - parser.add_argument("--output_path", type=str, default=None) - parser.add_argument( - "--eval_split", - type=str, - default="test", - choices=["train", "val", "valid", "validation", "test", "all"], - ) - parser.add_argument("--landmark_ages", type=str, default=None) - parser.add_argument("--landmark_start", type=float, default=40.0) - parser.add_argument("--landmark_stop", type=float, default=80.0) - parser.add_argument("--landmark_step", type=float, default=5.0) - parser.add_argument("--min_history_events", type=int, default=1) - parser.add_argument("--dataset_subset_size", type=int, default=0) - parser.add_argument("--readout_batch_size", type=int, default=8192) - parser.add_argument("--num_workers", type=int, default=4) - parser.add_argument("--device", type=str, default=None) - parser.add_argument("--devices", type=str, default=None) - parser.add_argument( - "--mp_start_method", - type=str, - default="fork", - choices=["fork", "forkserver"], - ) - args = parser.parse_args() - - run_path = Path(args.run_path) - devices = _parse_devices(args) - initial_device = "cpu" if len(devices) > 1 else devices[0] - ctx = load_deephealth_context(run_path, device=initial_device) - - disease_ids, matrices, mapping_counts = _load_index_matrices( - organ_mapping_csv=Path(args.organ_mapping_csv), - hfrs_mapping_csv=Path(args.hfrs_mapping_csv), - ) - landmark_ages = _parse_landmark_ages(args) - eval_split = str(args.eval_split).lower() - if eval_split in {"valid", "validation"}: - eval_split = "val" - subset_indices = _config_split_indices( - len(ctx.dataset), - ctx.cfg, - eval_split, - int(args.dataset_subset_size), - ) - rows = _eligible_landmark_rows( - ctx.dataset, - subset_indices, - landmark_ages, - min_history_events=int(args.min_history_events), - ) - if not rows: - raise RuntimeError("No eligible landmark rows.") - - output_path = Path(args.output_path) if args.output_path else ( - run_path / f"deephealth_indices_{eval_split}.csv" - ) - output_path.parent.mkdir(parents=True, exist_ok=True) - - chunks = _split_rows(rows, devices) - for device, chunk in chunks: - print( - f"Assigned {len(chunk)} rows / ~{sum(_estimate_jobs(r) for r in chunk)} " - f"readout jobs to {device}", - flush=True, - ) - - total_readout_jobs = 0 - timings = {"forward_sec": 0.0, "reduce_sec": 0.0, "write_csv_sec": 0.0} - if len(chunks) == 1: - out, total_readout_jobs, chunk_timings = _compute_rows( - rows=rows, - disease_ids=disease_ids, - matrices=matrices, - readout_batch_size=int(args.readout_batch_size), - num_workers=int(args.num_workers), - ctx=ctx, - log_prefix="[Index main]", - ) - for key, value in chunk_timings.items(): - timings[key] += float(value) - t0 = time.perf_counter() - _write_rows_csv(out, output_path) - timings["write_csv_sec"] = time.perf_counter() - t0 - else: - del ctx - payloads = [ - { - "device": device, - "run_path": str(run_path), - "shard_path": str( - output_path.with_name( - f"{output_path.stem}.part{part_idx:03d}{output_path.suffix}" - ) - ), - "row_specs": [_row_to_worker_spec(row) for row in chunk], - "disease_ids": disease_ids, - "matrices": matrices, - "readout_batch_size": int(args.readout_batch_size), - "num_workers": int(args.num_workers), - } - for part_idx, (device, chunk) in enumerate(chunks) - ] - shard_paths = [] - with ProcessPoolExecutor( - max_workers=len(payloads), - mp_context=mp.get_context(args.mp_start_method), - ) as executor: - futures = [executor.submit(_worker, payload) for payload in payloads] - for future in tqdm( - as_completed(futures), - total=len(futures), - desc="Computing DeepHealth index chunks", - dynamic_ncols=True, - ): - result = future.result() - shard_paths.append(Path(result["shard_path"])) - total_readout_jobs += int(result["readout_jobs"]) - for key, value in result["timings"].items(): - timings[key] += float(value) - t0 = time.perf_counter() - _concat_csv_shards(sorted(shard_paths), output_path) - timings["write_csv_sec"] += time.perf_counter() - t0 - - print(f"Run path: {run_path}") - print(f"Eval split: {eval_split}") - print(f"Landmark rows: {len(rows)}") - print(f"Readout jobs: {total_readout_jobs}") - print(f"Union disease tokens: {disease_ids.size}") - print(f"Organ mapped tokens: {mapping_counts['organ_mapped_tokens']}") - print(f"HFRS mapped tokens: {mapping_counts['hfrs_mapped_tokens']}") - print( - "Timing seconds: " - f"forward={timings['forward_sec']:.2f}, " - f"reduce={timings['reduce_sec']:.2f}, " - f"write_csv={timings['write_csv_sec']:.2f}" - ) - print(f"Devices: {', '.join(str(d) for d, _ in chunks)}") - print(f"Output: {output_path}") - - -if __name__ == "__main__": - main() diff --git a/organ_involvement_label_mapping.csv b/organ_involvement_label_mapping.csv deleted file mode 100644 index a35f2b9..0000000 --- a/organ_involvement_label_mapping.csv +++ /dev/null @@ -1,1257 +0,0 @@ -token_id,label_code,label_name,organ_id,organ_label,organ_weight,match_source,mapping_source -3,A00,(cholera),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -4,A01,(typhoid and paratyphoid fevers),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -5,A02,(other salmonella infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -6,A03,(shigellosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -7,A04,(other bacterial intestinal infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -8,A05,(other bacterial foodborne intoxications),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -9,A06,(amoebiasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -10,A07,(other protozoal intestinal diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -11,A08,(viral and other specified intestinal infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -12,A09,(diarrhoea and gastro-enteritis of presumed infectious origin),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -13,A15,"(respiratory tuberculosis, bacteriologically and histologically confirmed)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -14,A16,"(respiratory tuberculosis, not confirmed bacteriologically or histologically)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -15,A17,(tuberculosis of nervous system),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -16,A18,(tuberculosis of other organs),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -17,A19,(miliary tuberculosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -18,A20,(plague),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -19,A22,(anthrax),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -20,A23,(brucellosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -21,A24,(glanders and melioidosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -22,A25,(rat-bite fevers),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -23,A26,(erysipeloid),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -24,A27,(leptospirosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -25,A28,"(other zoonotic bacterial diseases, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -26,A30,(leprosy [hansen's disease]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -27,A31,(infection due to other mycobacteria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -28,A32,(listeriosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -29,A33,(tetanus neonatorum),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -30,A35,(other tetanus),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -31,A36,(diphtheria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -32,A37,(whooping cough),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -33,A38,(scarlet fever),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -34,A39,(meningococcal infection),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -35,A40,(streptococcal septicaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -36,A41,(other septicaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -37,A42,(actinomycosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -38,A43,(nocardiosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -39,A44,(bartonellosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -40,A46,(erysipelas),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -41,A48,"(other bacterial diseases, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -42,A49,(bacterial infection of unspecified site),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -43,A50,(congenital syphilis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -44,A51,(early syphilis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -45,A52,(late syphilis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -46,A53,(other and unspecified syphilis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -47,A54,(gonococcal infection),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -48,A55,(chlamydial lymphogranuloma (venereum)),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -49,A56,(other sexually transmitted chlamydial diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -50,A58,(granuloma inguinale),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -51,A59,(trichomoniasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -52,A60,(anogenital herpesviral [herpes simplex] infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -53,A63,"(other predominantly sexually transmitted diseases, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -54,A64,(unspecified sexually transmitted disease),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -55,A66,(yaws),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -56,A67,(pinta [carate]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -57,A68,(relapsing fevers),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -58,A69,(other spirochaetal infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -59,A70,(chlamydia psittaci infection),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -60,A71,(trachoma),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -61,A74,(other diseases caused by chlamydiae),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -62,A75,(typhus fever),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -63,A77,(spotted fever [tick-borne rickettsioses]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -64,A78,(q fever),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -65,A79,(other rickettsioses),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -66,A80,(acute poliomyelitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -67,A81,(atypical virus infections of central nervous system),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -68,A82,(rabies),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -69,A83,(mosquito-borne viral encephalitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -70,A84,(tick-borne viral encephalitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -71,A85,"(other viral encephalitis, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -72,A86,(unspecified viral encephalitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -73,A87,(viral meningitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -74,A88,"(other viral infections of central nervous system, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -75,A89,(unspecified viral infection of central nervous system),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -76,A90,(dengue fever [classical dengue]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -77,A91,(dengue haemorrhagic fever),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -78,A92,(other mosquito-borne viral fevers),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -79,A93,"(other arthropod-borne viral fevers, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -80,A94,(unspecified arthropod-borne viral fever),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -81,A95,(yellow fever),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -82,A97,(dengue),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -83,A98,"(other viral haemorrhagic fevers, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -84,B00,(herpesviral [herpes simplex] infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -85,B01,(varicella [chickenpox]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -86,B02,(zoster [herpes zoster]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -87,B03,(smallpox),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -88,B05,(measles),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -89,B06,(rubella [german measles]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -90,B07,(viral warts),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -91,B08,"(other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -92,B09,(unspecified viral infection characterised by skin and mucous membrane lesions),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -93,B15,(acute hepatitis a),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -94,B16,(acute hepatitis b),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -95,B17,(other acute viral hepatitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -96,B18,(chronic viral hepatitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -97,B19,(unspecified viral hepatitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -98,B20,(human immunodeficiency virus [hiv] disease resulting in infectious and parasitic diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -99,B21,(human immunodeficiency virus [hiv] disease resulting in malignant neoplasms),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -100,B22,(human immunodeficiency virus [hiv] disease resulting in other specified diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -101,B23,(human immunodeficiency virus [hiv] disease resulting in other conditions),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -102,B24,(unspecified human immunodeficiency virus [hiv] disease),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -103,B25,(cytomegaloviral disease),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -104,B26,(mumps),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -105,B27,(infectious mononucleosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -106,B30,(viral conjunctivitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -107,B33,"(other viral diseases, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -108,B34,(viral infection of unspecified site),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -109,B35,(dermatophytosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -110,B36,(other superficial mycoses),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -111,B37,(candidiasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -112,B38,(coccidioidomycosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -113,B39,(histoplasmosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -114,B40,(blastomycosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -115,B42,(sporotrichosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -116,B43,(chromomycosis and phaeomycotic abscess),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -117,B44,(aspergillosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -118,B45,(cryptococcosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -119,B46,(zygomycosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -120,B47,(mycetoma),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -121,B48,"(other mycoses, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -122,B49,(unspecified mycosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -123,B50,(plasmodium falciparum malaria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -124,B51,(plasmodium vivax malaria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -125,B52,(plasmodium malariae malaria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -126,B53,(other parasitologically confirmed malaria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -127,B54,(unspecified malaria),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -128,B55,(leishmaniasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -129,B57,(chagas' disease),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -130,B58,(toxoplasmosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -131,B59,(pneumocystosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -132,B60,"(other protozoal diseases, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -133,B65,(schistosomiasis [bilharziasis]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -134,B66,(other fluke infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -135,B67,(echinococcosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -136,B68,(taeniasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -137,B69,(cysticercosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -138,B71,(other cestode infections),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -139,B73,(onchocerciasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -140,B74,(filariasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -141,B75,(trichinellosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -142,B76,(hookworm diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -143,B77,(ascariasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -144,B78,(strongyloidiasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -145,B79,(trichuriasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -146,B80,(enterobiasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -147,B81,"(other intestinal helminthiases, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -148,B82,(unspecified intestinal parasitism),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -149,B83,(other helminthiases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -150,B85,(pediculosis and phthiriasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -151,B86,(scabies),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -152,B87,(myiasis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -153,B88,(other infestations),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -154,B89,(unspecified parasitic disease),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -155,B90,(sequelae of tuberculosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -156,B91,(sequelae of poliomyelitis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -157,B94,(sequelae of other and unspecified infectious and parasitic diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -158,B95,(streptococcus and staphylococcus as the cause of diseases classified to other chapters),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -159,B96,(other bacterial agents as the cause of diseases classified to other chapters),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -160,B97,(viral agents as the cause of diseases classified to other chapters),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -161,B98,(other specified infectious agents as the cause of diseases classified to other chapters),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -162,B99,(other and unspecified infectious diseases),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -163,D50,(iron deficiency anaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -164,D51,(vitamin b12 deficiency anaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -165,D52,(folate deficiency anaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -166,D53,(other nutritional anaemias),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -167,D55,(anaemia due to enzyme disorders),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -168,D56,(thalassaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -169,D57,(sickle-cell disorders),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -170,D58,(other hereditary haemolytic anaemias),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -171,D59,(acquired haemolytic anaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -172,D60,(acquired pure red cell aplasia [erythroblastopenia]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -173,D61,(other aplastic anaemias),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -174,D62,(acute posthaemorrhagic anaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -175,D63,(anaemia in chronic diseases classified elsewhere),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -176,D64,(other anaemias),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -177,D65,(disseminated intravascular coagulation [defibrination syndrome]),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -178,D66,(hereditary factor viii deficiency),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -179,D67,(hereditary factor ix deficiency),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -180,D68,(other coagulation defects),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -181,D69,(purpura and other haemorrhagic conditions),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -182,D70,(agranulocytosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -183,D71,(functional disorders of polymorphonuclear neutrophils),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -184,D72,(other disorders of white blood cells),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -185,D73,(diseases of spleen),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -186,D74,(methaemoglobinaemia),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -187,D75,(other diseases of blood and blood-forming organs),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -188,D76,(certain diseases involving lymphoreticular tissue and reticulohistiocytic system),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -189,D77,(other disorders of blood and blood-forming organs in diseases classified elsewhere),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -190,D80,(immunodeficiency with predominantly antibody defects),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -191,D81,(combined immunodeficiencies),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -192,D82,(immunodeficiency associated with other major defects),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -193,D83,(common variable immunodeficiency),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -194,D84,(other immunodeficiencies),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -195,D86,(sarcoidosis),immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -196,D89,"(other disorders involving the immune mechanism, not elsewhere classified)",immune,immune,1.0,a00_b99_d50_d89,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -197,E01,(iodine-deficiency-related thyroid disorders and allied conditions),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -198,E02,(subclinical iodine-deficiency hypothyroidism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -199,E03,(other hypothyroidism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -200,E04,(other non-toxic goitre),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -201,E05,(thyrotoxicosis [hyperthyroidism]),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -202,E06,(thyroiditis),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -203,E07,(other disorders of thyroid),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -204,E10,(insulin-dependent diabetes mellitus),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -205,E11,(non-insulin-dependent diabetes mellitus),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -206,E12,(malnutrition-related diabetes mellitus),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -207,E13,(other specified diabetes mellitus),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -208,E14,(unspecified diabetes mellitus),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -209,E15,(nondiabetic hypoglycaemic coma),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -210,E16,(other disorders of pancreatic internal secretion),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -211,E20,(hypoparathyroidism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -212,E21,(hyperparathyroidism and other disorders of parathyroid gland),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -213,E22,(hyperfunction of pituitary gland),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -214,E23,(hypofunction and other disorders of pituitary gland),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -215,E24,(cushing's syndrome),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -216,E25,(adrenogenital disorders),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -217,E26,(hyperaldosteronism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -218,E27,(other disorders of adrenal gland),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -219,E28,(ovarian dysfunction),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -220,E29,(testicular dysfunction),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -221,E30,"(disorders of puberty, not elsewhere classified)",adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -222,E31,(polyglandular dysfunction),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -223,E32,(diseases of thymus),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -224,E34,(other endocrine disorders),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -225,E35,(disorders of endocrine glands in diseases classified elsewhere),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -226,E41,(nutritional marasmus),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -227,E43,(unspecified severe protein-energy malnutrition),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -228,E44,(protein-energy malnutrition of moderate and mild degree),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -229,E45,(retarded development following protein-energy malnutrition),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -230,E46,(unspecified protein-energy malnutrition),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -231,E50,(vitamin a deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -232,E51,(thiamine deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -233,E52,(niacin deficiency [pellagra]),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -234,E53,(deficiency of other b group vitamins),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -235,E54,(ascorbic acid deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -236,E55,(vitamin d deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -237,E56,(other vitamin deficiencies),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -238,E58,(dietary calcium deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -239,E59,(dietary selenium deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -240,E60,(dietary zinc deficiency),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -241,E61,(deficiency of other nutrient elements),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -242,E63,(other nutritional deficiencies),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -243,E64,(sequelae of malnutrition and other nutritional deficiencies),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -244,E65,(localised adiposity),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -245,E66,(obesity),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -246,E67,(other hyperalimentation),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -247,E68,(sequelae of hyperalimentation),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -248,E70,(disorders of aromatic amino-acid metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -249,E71,(disorders of branched-chain amino-acid metabolism and fatty-acid metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -250,E72,(other disorders of amino-acid metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -251,E73,(lactose intolerance),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -252,E74,(other disorders of carbohydrate metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -253,E75,(disorders of sphingolipid metabolism and other lipid storage disorders),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -254,E76,(disorders of glycosaminoglycan metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -255,E77,(disorders of glycoprotein metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -256,E78,(disorders of lipoprotein metabolism and other lipidaemias),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -257,E79,(disorders of purine and pyrimidine metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -258,E80,(disorders of porphyrin and bilirubin metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -259,E83,(disorders of mineral metabolism),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -260,E84,(cystic fibrosis),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -261,E85,(amyloidosis),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -262,E86,(volume depletion),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -263,E87,"(other disorders of fluid, electrolyte and acid-base balance)",adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -264,E88,(other metabolic disorders),adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -265,E89,"(postprocedural endocrine and metabolic disorders, not elsewhere classified)",adipose_metabolic,adipose_metabolic,1.0,e00_e09_e17_e90,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -266,F00,(dementia in alzheimer's disease),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -267,F01,(vascular dementia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -268,F02,(dementia in other diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -269,F03,(unspecified dementia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -270,F04,"(organic amnesic syndrome, not induced by alcohol and other psychoactive substances)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -271,F05,"(delirium, not induced by alcohol and other psychoactive substances)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -272,F06,(other mental disorders due to brain damage and dysfunction and to physical disease),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -273,F07,"(personality and behavioural disorders due to brain disease, damage and dysfunction)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -274,F09,(unspecified organic or symptomatic mental disorder),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -275,F10,(mental and behavioural disorders due to use of alcohol),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -276,F11,(mental and behavioural disorders due to use of opioids),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -277,F12,(mental and behavioural disorders due to use of cannabinoids),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -278,F13,(mental and behavioural disorders due to use of sedatives or hypnotics),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -279,F14,(mental and behavioural disorders due to use of cocaine),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -280,F15,"(mental and behavioural disorders due to use of other stimulants, including caffeine)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -281,F16,(mental and behavioural disorders due to use of hallucinogens),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -282,F17,(mental and behavioural disorders due to use of tobacco),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -283,F18,(mental and behavioural disorders due to use of volatile solvents),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -284,F19,(mental and behavioural disorders due to multiple drug use and use of other psychoactive substances),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -285,F20,(schizophrenia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -286,F21,(schizotypal disorder),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -287,F22,(persistent delusional disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -288,F23,(acute and transient psychotic disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -289,F24,(induced delusional disorder),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -290,F25,(schizoaffective disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -291,F28,(other nonorganic psychotic disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -292,F29,(unspecified nonorganic psychosis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -293,F30,(manic episode),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -294,F31,(bipolar affective disorder),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -295,F32,(depressive episode),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -296,F33,(recurrent depressive disorder),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -297,F34,(persistent mood [affective] disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -298,F38,(other mood [affective] disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -299,F39,(unspecified mood [affective] disorder),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -300,F40,(phobic anxiety disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -301,F41,(other anxiety disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -302,F42,(obsessive-compulsive disorder),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -303,F43,"(reaction to severe stress, and adjustment disorders)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -304,F44,(dissociative [conversion] disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -305,F45,(somatoform disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -306,F48,(other neurotic disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -307,F50,(eating disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -308,F51,(nonorganic sleep disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -309,F52,"(sexual dysfunction, not caused by organic disorder or disease)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -310,F53,"(mental and behavioural disorders associated with the puerperium, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -311,F54,(psychological and behavioural factors associated with disorders or diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -312,F55,(abuse of non-dependence-producing substances),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -313,F59,(unspecified behavioural syndromes associated with physiological disturbances and physical factors),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -314,F60,(specific personality disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -315,F61,(mixed and other personality disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -316,F62,"(enduring personality changes, not attributable to brain damage and disease)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -317,F63,(habit and impulse disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -318,F64,(gender identity disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -319,F65,(disorders of sexual preference),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -320,F66,(psychological and behavioural disorders associated with sexual development and orientation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -321,F68,(other disorders of adult personality and behaviour),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -322,F69,(unspecified disorder of adult personality and behaviour),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -323,F70,(mild mental retardation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -324,F71,(moderate mental retardation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -325,F72,(severe mental retardation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -326,F78,(other mental retardation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -327,F79,(unspecified mental retardation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -328,F80,(specific developmental disorders of speech and language),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -329,F81,(specific developmental disorders of scholastic skills),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -330,F82,(specific developmental disorder of motor function),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -331,F83,(mixed specific developmental disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -332,F84,(pervasive developmental disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -333,F88,(other disorders of psychological development),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -334,F89,(unspecified disorder of psychological development),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -335,F90,(hyperkinetic disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -336,F91,(conduct disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -337,F92,(mixed disorders of conduct and emotions),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -338,F93,(emotional disorders with onset specific to childhood),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -339,F94,(disorders of social functioning with onset specific to childhood and adolescence),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -340,F95,(tic disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -341,F98,(other behavioural and emotional disorders with onset usually occurring in childhood and adolescence),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -342,F99,"(mental disorder, not otherwise specified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -343,G00,"(bacterial meningitis, not elsewhere classified)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -344,G01,(meningitis in bacterial diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -345,G02,(meningitis in other infectious and parasitic diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -346,G03,(meningitis due to other and unspecified causes),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -347,G04,"(encephalitis, myelitis and encephalomyelitis)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -348,G05,"(encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -349,G06,(intracranial and intraspinal abscess and granuloma),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -350,G07,(intracranial and intraspinal abscess and granuloma in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -351,G08,(intracranial and intraspinal phlebitis and thrombophlebitis),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -352,G09,(sequelae of inflammatory diseases of central nervous system),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -353,G10,(huntington's disease),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -354,G11,(hereditary ataxia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -355,G12,(spinal muscular atrophy and related syndromes),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -356,G13,(systemic atrophies primarily affecting central nervous system in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -357,G14,(postpolio syndrome),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -358,G20,(parkinson's disease),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -359,G21,(secondary parkinsonism),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -360,G22,(parkinsonism in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -361,G23,(other degenerative diseases of basal ganglia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -362,G24,(dystonia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -363,G25,(other extrapyramidal and movement disorders),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -364,G30,(alzheimer's disease),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -365,G31,"(other degenerative diseases of nervous system, not elsewhere classified)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -366,G32,(other degenerative disorders of nervous system in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -367,G35,(multiple sclerosis),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -368,G36,(other acute disseminated demyelination),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -369,G37,(other demyelinating diseases of central nervous system),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -370,G40,(epilepsy),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -371,G41,(status epilepticus),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -372,G43,(migraine),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -373,G44,(other headache syndromes),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -374,G45,(transient cerebral ischaemic attacks and related syndromes),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -375,G46,(vascular syndromes of brain in cerebrovascular diseases),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -376,G47,(sleep disorders),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -377,G50,(disorders of trigeminal nerve),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -378,G51,(facial nerve disorders),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -379,G52,(disorders of other cranial nerves),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -380,G53,(cranial nerve disorders in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -381,G54,(nerve root and plexus disorders),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -382,G55,(nerve root and plexus compressions in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -383,G56,(mononeuropathies of upper limb),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -384,G57,(mononeuropathies of lower limb),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -385,G58,(other mononeuropathies),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -386,G59,(mononeuropathy in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -387,G60,(hereditary and idiopathic neuropathy),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -388,G61,(inflammatory polyneuropathy),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -389,G62,(other polyneuropathies),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -390,G63,(polyneuropathy in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -391,G64,(other disorders of peripheral nervous system),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -392,G70,(myasthenia gravis and other myoneural disorders),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -393,G71,(primary disorders of muscles),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -394,G72,(other myopathies),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -395,G73,(disorders of myoneural junction and muscle in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -396,G80,(infantile cerebral palsy),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -397,G81,(hemiplegia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -398,G82,(paraplegia and tetraplegia),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -399,G83,(other paralytic syndromes),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -400,G90,(disorders of autonomic nervous system),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -401,G91,(hydrocephalus),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -402,G92,(toxic encephalopathy),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -403,G93,(other disorders of brain),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -404,G94,(other disorders of brain in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -405,G95,(other diseases of spinal cord),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -406,G96,(other disorders of central nervous system),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -407,G97,"(postprocedural disorders of nervous system, not elsewhere classified)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -408,G98,"(other disorders of nervous system, not elsewhere classified)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -409,G99,(other disorders of nervous system in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -410,H00,(hordeolum and chalazion),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -411,H01,(other inflammation of eyelid),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -412,H02,(other disorders of eyelid),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -413,H03,(disorders of eyelid in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -414,H04,(disorders of lachrymal system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -415,H05,(disorders of orbit),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -416,H06,(disorders of lachrymal system and orbit in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -417,H10,(conjunctivitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -418,H11,(other disorders of conjunctiva),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -419,H13,(disorders of conjunctiva in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -420,H15,(disorders of sclera),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -421,H16,(keratitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -422,H17,(corneal scars and opacities),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -423,H18,(other disorders of cornea),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -424,H19,(disorders of sclera and cornea in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -425,H20,(iridocyclitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -426,H21,(other disorders of iris and ciliary body),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -427,H22,(disorders of iris and ciliary body in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -428,H25,(senile cataract),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -429,H26,(other cataract),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -430,H27,(other disorders of lens),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -431,H28,(cataract and other disorders of lens in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -432,H30,(chorioretinal inflammation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -433,H31,(other disorders of choroid),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -434,H32,(chorioretinal disorders in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -435,H33,(retinal detachments and breaks),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -436,H34,(retinal vascular occlusions),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -437,H35,(other retinal disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -438,H36,(retinal disorders in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -439,H40,(glaucoma),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -440,H42,(glaucoma in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -441,H43,(disorders of vitreous body),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -442,H44,(disorders of globe),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -443,H45,(disorders of vitreous body and globe in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -444,H46,(optic neuritis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -445,H47,(other disorders of optic [2nd] nerve and visual pathways),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -446,H48,(disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -447,H49,(paralytic strabismus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -448,H50,(other strabismus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -449,H51,(other disorders of binocular movement),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -450,H52,(disorders of refraction and accommodation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -451,H53,(visual disturbances),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -452,H54,(blindness and low vision),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -453,H55,(nystagmus and other irregular eye movements),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -454,H57,(other disorders of eye and adnexa),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -455,H58,(other disorders of eye and adnexa in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -456,H59,"(postprocedural disorders of eye and adnexa, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -457,H60,(otitis externa),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -458,H61,(other disorders of external ear),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -459,H62,(disorders of external ear in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -460,H65,(nonsuppurative otitis media),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -461,H66,(suppurative and unspecified otitis media),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -462,H67,(otitis media in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -463,H68,(eustachian salpingitis and obstruction),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -464,H69,(other disorders of eustachian tube),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -465,H70,(mastoiditis and related conditions),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -466,H71,(cholesteatoma of middle ear),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -467,H72,(perforation of tympanic membrane),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -468,H73,(other disorders of tympanic membrane),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -469,H74,(other disorders of middle ear and mastoid),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -470,H75,(other disorders of middle ear and mastoid in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -471,H80,(otosclerosis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -472,H81,(disorders of vestibular function),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -473,H82,(vertiginous syndromes in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -474,H83,(other diseases of inner ear),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -475,H90,(conductive and sensorineural hearing loss),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -476,H91,(other hearing loss),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -477,H92,(otalgia and effusion of ear),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -478,H93,"(other disorders of ear, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -479,H94,(other disorders of ear in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -480,H95,"(postprocedural disorders of ear and mastoid process, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -481,I00,(rheumatic fever without mention of heart involvement),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -482,I01,(rheumatic fever with heart involvement),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -483,I02,(rheumatic chorea),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -484,I05,(rheumatic mitral valve diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -485,I06,(rheumatic aortic valve diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -486,I07,(rheumatic tricuspid valve diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -487,I08,(multiple valve diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -488,I09,(other rheumatic heart diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -489,I10,(essential (primary) hypertension),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -490,I11,(hypertensive heart disease),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -491,I12,(hypertensive renal disease),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -492,I13,(hypertensive heart and renal disease),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -493,I15,(secondary hypertension),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -494,I20,(angina pectoris),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -495,I21,(acute myocardial infarction),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -496,I22,(subsequent myocardial infarction),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -497,I23,(certain current complications following acute myocardial infarction),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -498,I24,(other acute ischaemic heart diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -499,I25,(chronic ischaemic heart disease),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -500,I26,(pulmonary embolism),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -501,I27,(other pulmonary heart diseases),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -502,I28,(other diseases of pulmonary vessels),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -503,I30,(acute pericarditis),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -504,I31,(other diseases of pericardium),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -505,I32,(pericarditis in diseases classified elsewhere),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -506,I33,(acute and subacute endocarditis),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -507,I34,(nonrheumatic mitral valve disorders),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -508,I35,(nonrheumatic aortic valve disorders),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -509,I36,(nonrheumatic tricuspid valve disorders),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -510,I37,(pulmonary valve disorders),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -511,I38,"(endocarditis, valve unspecified)",heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -512,I39,(endocarditis and heart valve disorders in diseases classified elsewhere),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -513,I40,(acute myocarditis),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -514,I41,(myocarditis in diseases classified elsewhere),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -515,I42,(cardiomyopathy),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -516,I43,(cardiomyopathy in diseases classified elsewhere),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -517,I44,(atrioventricular and left bundle-branch block),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -518,I45,(other conduction disorders),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -519,I46,(cardiac arrest),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -520,I47,(paroxysmal tachycardia),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -521,I48,(atrial fibrillation and flutter),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -522,I49,(other cardiac arrhythmias),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -523,I50,(heart failure),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -524,I51,(complications and ill-defined descriptions of heart disease),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -525,I52,(other heart disorders in diseases classified elsewhere),heart,heart,1.0,i00_i09_i20_i52,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -526,I60,(subarachnoid haemorrhage),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -527,I61,(intracerebral haemorrhage),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -528,I62,(other nontraumatic intracranial haemorrhage),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -529,I63,(cerebral infarction),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -530,I64,"(stroke, not specified as haemorrhage or infarction)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -531,I65,"(occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -532,I66,"(occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction)",brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -533,I67,(other cerebrovascular diseases),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -534,I68,(cerebrovascular disorders in diseases classified elsewhere),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -535,I69,(sequelae of cerebrovascular disease),brain_neurologic,brain_neurologic,1.0,f00_f09_g00_g99_i60_i69,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -536,I70,(atherosclerosis),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -537,I71,(aortic aneurysm and dissection),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -538,I72,(other aneurysm),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -539,I73,(other peripheral vascular diseases),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -540,I74,(arterial embolism and thrombosis),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -541,I77,(other disorders of arteries and arterioles),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -542,I78,(diseases of capillaries),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -543,I79,"(disorders of arteries, arterioles and capillaries in diseases classified elsewhere)",artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -544,I80,(phlebitis and thrombophlebitis),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -545,I81,(portal vein thrombosis),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -546,I82,(other venous embolism and thrombosis),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -547,I83,(varicose veins of lower extremities),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -548,I84,(haemorrhoids),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -549,I85,(oesophageal varices),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -550,I86,(varicose veins of other sites),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -551,I87,(other disorders of veins),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -552,I88,(nonspecific lymphadenitis),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -553,I89,(other non-infective disorders of lymphatic vessels and lymph nodes),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -554,I95,(hypotension),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -555,I97,"(postprocedural disorders of circulatory system, not elsewhere classified)",artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -556,I98,(other disorders of circulatory system in diseases classified elsewhere),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -557,I99,(other and unspecified disorders of circulatory system),artery_vascular,artery_vascular,1.0,i10_i15_i70_i89_i95_i99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -558,J00,(acute nasopharyngitis [common cold]),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -559,J01,(acute sinusitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -560,J02,(acute pharyngitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -561,J03,(acute tonsillitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -562,J04,(acute laryngitis and tracheitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -563,J05,(acute obstructive laryngitis [croup] and epiglottitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -564,J06,(acute upper respiratory infections of multiple and unspecified sites),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -565,J09,(influenza due to certain identified influenza virus),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -566,J10,(influenza due to identified influenza virus),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -567,J11,"(influenza, virus not identified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -568,J12,"(viral pneumonia, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -569,J13,(pneumonia due to streptococcus pneumoniae),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -570,J14,(pneumonia due to haemophilus influenzae),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -571,J15,"(bacterial pneumonia, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -572,J16,"(pneumonia due to other infectious organisms, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -573,J17,(pneumonia in diseases classified elsewhere),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -574,J18,"(pneumonia, organism unspecified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -575,J20,(acute bronchitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -576,J21,(acute bronchiolitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -577,J22,(unspecified acute lower respiratory infection),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -578,J30,(vasomotor and allergic rhinitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -579,J31,"(chronic rhinitis, nasopharyngitis and pharyngitis)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -580,J32,(chronic sinusitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -581,J33,(nasal polyp),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -582,J34,(other disorders of nose and nasal sinuses),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -583,J35,(chronic diseases of tonsils and adenoids),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -584,J36,(peritonsillar abscess),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -585,J37,(chronic laryngitis and laryngotracheitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -586,J38,"(diseases of vocal cords and larynx, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -587,J39,(other diseases of upper respiratory tract),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -588,J40,"(bronchitis, not specified as acute or chronic)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -589,J41,(simple and mucopurulent chronic bronchitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -590,J42,(unspecified chronic bronchitis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -591,J43,(emphysema),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -592,J44,(other chronic obstructive pulmonary disease),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -593,J45,(asthma),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -594,J46,(status asthmaticus),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -595,J47,(bronchiectasis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -596,J60,(coalworker's pneumoconiosis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -597,J61,(pneumoconiosis due to asbestos and other mineral fibres),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -598,J62,(pneumoconiosis due to dust containing silica),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -599,J63,(pneumoconiosis due to other inorganic dusts),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -600,J64,(unspecified pneumoconiosis),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -601,J66,(airway disease due to specific organic dust),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -602,J67,(hypersensitivity pneumonitis due to organic dust),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -603,J68,"(respiratory conditions due to inhalation of chemicals, gases, fumes and vapours)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -604,J69,(pneumonitis due to solids and liquids),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -605,J70,(respiratory conditions due to other external agents),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -606,J80,(adult respiratory distress syndrome),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -607,J81,(pulmonary oedema),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -608,J82,"(pulmonary eosinophilia, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -609,J84,(other interstitial pulmonary diseases),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -610,J85,(abscess of lung and mediastinum),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -611,J86,(pyothorax),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -612,J90,"(pleural effusion, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -613,J91,(pleural effusion in conditions classified elsewhere),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -614,J92,(pleural plaque),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -615,J93,(pneumothorax),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -616,J94,(other pleural conditions),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -617,J95,"(postprocedural respiratory disorders, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -618,J96,"(respiratory failure, not elsewhere classified)",lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -619,J98,(other respiratory disorders),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -620,J99,(respiratory disorders in diseases classified elsewhere),lung,lung,1.0,j00_j99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -621,K00,(disorders of tooth development and eruption),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -622,K01,(embedded and impacted teeth),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -623,K02,(dental caries),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -624,K03,(other diseases of hard tissues of teeth),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -625,K04,(diseases of pulp and periapical tissues),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -626,K05,(gingivitis and periodontal diseases),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -627,K06,(other disorders of gingiva and edentulous alveolar ridge),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -628,K07,(dentofacial anomalies [including malocclusion]),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -629,K08,(other disorders of teeth and supporting structures),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -630,K09,"(cysts of oral region, not elsewhere classified)",intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -631,K10,(other diseases of jaws),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -632,K11,(diseases of salivary glands),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -633,K12,(stomatitis and related lesions),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -634,K13,(other diseases of lip and oral mucosa),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -635,K14,(diseases of tongue),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -636,K20,(oesophagitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -637,K21,(gastro-oesophageal reflux disease),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -638,K22,(other diseases of oesophagus),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -639,K23,(disorders of oesophagus in diseases classified elsewhere),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -640,K25,(gastric ulcer),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -641,K26,(duodenal ulcer),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -642,K27,"(peptic ulcer, site unspecified)",intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -643,K28,(gastrojejunal ulcer),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -644,K29,(gastritis and duodenitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -645,K30,(dyspepsia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -646,K31,(other diseases of stomach and duodenum),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -647,K35,(acute appendicitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -648,K36,(other appendicitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -649,K37,(unspecified appendicitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -650,K38,(other diseases of appendix),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -651,K40,(inguinal hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -652,K41,(femoral hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -653,K42,(umbilical hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -654,K43,(ventral hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -655,K44,(diaphragmatic hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -656,K45,(other abdominal hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -657,K46,(unspecified abdominal hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -658,K50,(crohn's disease [regional enteritis]),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -659,K51,(ulcerative colitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -660,K52,(other non-infective gastro-enteritis and colitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -661,K55,(vascular disorders of intestine),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -662,K56,(paralytic ileus and intestinal obstruction without hernia),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -663,K57,(diverticular disease of intestine),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -664,K58,(irritable bowel syndrome),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -665,K59,(other functional intestinal disorders),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -666,K60,(fissure and fistula of anal and rectal regions),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -667,K61,(abscess of anal and rectal regions),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -668,K62,(other diseases of anus and rectum),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -669,K63,(other diseases of intestine),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -670,K64,(haemorrhoids and perianal venous thrombosis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -671,K65,(peritonitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -672,K66,(other disorders of peritoneum),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -673,K67,(disorders of peritoneum in infectious diseases classified elsewhere),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -674,K70,(alcoholic liver disease),liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -675,K71,(toxic liver disease),liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -676,K72,"(hepatic failure, not elsewhere classified)",liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -677,K73,"(chronic hepatitis, not elsewhere classified)",liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -678,K74,(fibrosis and cirrhosis of liver),liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -679,K75,(other inflammatory liver diseases),liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -680,K76,(other diseases of liver),liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -681,K77,(liver disorders in diseases classified elsewhere),liver,liver,1.0,k70_k77,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -682,K80,(cholelithiasis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -683,K81,(cholecystitis),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -684,K82,(other diseases of gallbladder),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -685,K83,(other diseases of biliary tract),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -686,K85,(acute pancreatitis),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -687,K86,(other diseases of pancreas),pancreas_endocrine,pancreas_endocrine,1.0,k85_k86_e10_e16,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -688,K87,"(disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere)",intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -689,K90,(intestinal malabsorption),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -690,K91,"(postprocedural disorders of digestive system, not elsewhere classified)",intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -691,K92,(other diseases of digestive system),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -692,K93,(disorders of other digestive organs in diseases classified elsewhere),intestine_digestive,intestine_digestive,1.0,k00_k69_k78_k84_k87_k93,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -693,L00,(staphylococcal scalded skin syndrome),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -694,L01,(impetigo),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -695,L02,"(cutaneous abscess, furuncle and carbuncle)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -696,L03,(cellulitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -697,L04,(acute lymphadenitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -698,L05,(pilonidal cyst),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -699,L08,(other local infections of skin and subcutaneous tissue),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -700,L10,(pemphigus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -701,L11,(other acantholytic disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -702,L12,(pemphigoid),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -703,L13,(other bullous disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -704,L14,(bullous disorders in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -705,L20,(atopic dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -706,L21,(seborrhoeic dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -707,L22,(diaper [napkin] dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -708,L23,(allergic contact dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -709,L24,(irritant contact dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -710,L25,(unspecified contact dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -711,L26,(exfoliative dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -712,L27,(dermatitis due to substances taken internally),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -713,L28,(lichen simplex chronicus and prurigo),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -714,L29,(pruritus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -715,L30,(other dermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -716,L40,(psoriasis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -717,L41,(parapsoriasis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -718,L42,(pityriasis rosea),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -719,L43,(lichen planus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -720,L44,(other papulosquamous disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -721,L50,(urticaria),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -722,L51,(erythema multiforme),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -723,L52,(erythema nodosum),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -724,L53,(other erythematous conditions),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -725,L54,(erythema in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -726,L55,(sunburn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -727,L56,(other acute skin changes due to ultraviolet radiation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -728,L57,(skin changes due to chronic exposure to nonionising radiation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -729,L58,(radiodermatitis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -730,L59,(other disorders of skin and subcutaneous tissue related to radiation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -731,L60,(nail disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -732,L62,(nail disorders in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -733,L63,(alopecia areata),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -734,L64,(androgenic alopecia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -735,L65,(other nonscarring hair loss),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -736,L66,(cicatricial alopecia [scarring hair loss]),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -737,L67,(hair colour and hair shaft abnormalities),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -738,L68,(hypertrichosis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -739,L70,(acne),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -740,L71,(rosacea),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -741,L72,(follicular cysts of skin and subcutaneous tissue),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -742,L73,(other follicular disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -743,L74,(eccrine sweat disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -744,L75,(apocrine sweat disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -745,L80,(vitiligo),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -746,L81,(other disorders of pigmentation),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -747,L82,(seborrhoeic keratosis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -748,L83,(acanthosis nigricans),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -749,L84,(corns and callosities),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -750,L85,(other epidermal thickening),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -751,L86,(keratoderma in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -752,L87,(transepidermal elimination disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -753,L88,(pyoderma gangrenosum),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -754,L89,(decubitus ulcer),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -755,L90,(atrophic disorders of skin),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -756,L91,(hypertrophic disorders of skin),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -757,L92,(granulomatous disorders of skin and subcutaneous tissue),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -758,L93,(lupus erythematosus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -759,L94,(other localised connective tissue disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -760,L95,"(vasculitis limited to skin, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -761,L97,"(ulcer of lower limb, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -762,L98,"(other disorders of skin and subcutaneous tissue, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -763,L99,(other disorders of skin and subcutaneous tissue in diseases classified elsewhere),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -764,M00,(pyogenic arthritis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -765,M01,(direct infections of joint in infectious and parasitic diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -766,M02,(reactive arthropathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -767,M03,(postinfective and reactive arthropathies in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -768,M05,(seropositive rheumatoid arthritis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -769,M06,(other rheumatoid arthritis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -770,M07,(psoriatic and enteropathic arthropathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -771,M08,(juvenile arthritis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -772,M09,(juvenile arthritis in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -773,M10,(gout),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -774,M11,(other crystal arthropathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -775,M12,(other specific arthropathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -776,M13,(other arthritis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -777,M14,(arthropathies in other diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -778,M15,(polyarthrosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -779,M16,(coxarthrosis [arthrosis of hip]),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -780,M17,(gonarthrosis [arthrosis of knee]),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -781,M18,(arthrosis of first carpometacarpal joint),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -782,M19,(other arthrosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -783,M20,(acquired deformities of fingers and toes),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -784,M21,(other acquired deformities of limbs),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -785,M22,(disorders of patella),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -786,M23,(internal derangement of knee),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -787,M24,(other specific joint derangements),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -788,M25,"(other joint disorders, not elsewhere classified)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -789,M30,(polyarteritis nodosa and related conditions),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -790,M31,(other necrotising vasculopathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -791,M32,(systemic lupus erythematosus),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -792,M33,(dermatopolymyositis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -793,M34,(systemic sclerosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -794,M35,(other systemic involvement of connective tissue),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -795,M36,(systemic disorders of connective tissue in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -796,M40,(kyphosis and lordosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -797,M41,(scoliosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -798,M42,(spinal osteochondrosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -799,M43,(other deforming dorsopathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -800,M45,(ankylosing spondylitis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -801,M46,(other inflammatory spondylopathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -802,M47,(spondylosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -803,M48,(other spondylopathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -804,M49,(spondylopathies in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -805,M50,(cervical disk disorders),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -806,M51,(other intervertebral disk disorders),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -807,M53,"(other dorsopathies, not elsewhere classified)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -808,M54,(dorsalgia),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -809,M60,(myositis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -810,M61,(calcification and ossification of muscle),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -811,M62,(other disorders of muscle),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -812,M63,(disorders of muscle in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -813,M65,(synovitis and tenosynovitis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -814,M66,(spontaneous rupture of synovium and tendon),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -815,M67,(other disorders of synovium and tendon),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -816,M68,(disorders of synovium and tendon in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -817,M70,"(soft tissue disorders related to use, overuse and pressure)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -818,M71,(other bursopathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -819,M72,(fibroblastic disorders),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -820,M73,(soft tissue disorders in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -821,M75,(shoulder lesions),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -822,M76,"(enthesopathies of lower limb, excluding foot)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -823,M77,(other enthesopathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -824,M79,"(other soft tissue disorders, not elsewhere classified)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -825,M80,(osteoporosis with pathological fracture),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -826,M81,(osteoporosis without pathological fracture),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -827,M82,(osteoporosis in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -828,M83,(adult osteomalacia),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -829,M84,(disorders of continuity of bone),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -830,M85,(other disorders of bone density and structure),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -831,M86,(osteomyelitis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -832,M87,(osteonecrosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -833,M88,(paget's disease of bone [osteitis deformans]),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -834,M89,(other disorders of bone),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -835,M90,(osteopathies in diseases classified elsewhere),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -836,M91,(juvenile osteochondrosis of hip and pelvis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -837,M92,(other juvenile osteochondrosis),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -838,M93,(other osteochondropathies),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -839,M94,(other disorders of cartilage),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -840,M95,(other acquired deformities of musculoskeletal system and connective tissue),muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -841,M96,"(postprocedural musculoskeletal disorders, not elsewhere classified)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -842,M99,"(biomechanical lesions, not elsewhere classified)",muscle_musculoskeletal,muscle_musculoskeletal,1.0,m00_m99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -843,N00,(acute nephritic syndrome),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -844,N01,(rapidly progressive nephritic syndrome),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -845,N02,(recurrent and persistent haematuria),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -846,N03,(chronic nephritic syndrome),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -847,N04,(nephrotic syndrome),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -848,N05,(unspecified nephritic syndrome),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -849,N06,(isolated proteinuria with specified morphological lesion),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -850,N07,"(hereditary nephropathy, not elsewhere classified)",kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -851,N08,(glomerular disorders in diseases classified elsewhere),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -852,N10,(acute tubulo-interstitial nephritis),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -853,N11,(chronic tubulo-interstitial nephritis),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -854,N12,"(tubulo-interstitial nephritis, not specified as acute or chronic)",kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -855,N13,(obstructive and reflux uropathy),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -856,N14,(drug- and heavy-metal-induced tubulo-interstitial and tubular conditions),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -857,N15,(other renal tubulo-interstitial diseases),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -858,N16,(renal tubulo-interstitial disorders in diseases classified elsewhere),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -859,N17,(acute renal failure),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -860,N18,(chronic renal failure),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -861,N19,(unspecified renal failure),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -862,N20,(calculus of kidney and ureter),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -863,N21,(calculus of lower urinary tract),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -864,N22,(calculus of urinary tract in diseases classified elsewhere),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -865,N23,(unspecified renal colic),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -866,N25,(disorders resulting from impaired renal tubular function),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -867,N26,(unspecified contracted kidney),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -868,N27,(small kidney of unknown cause),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -869,N28,"(other disorders of kidney and ureter, not elsewhere classified)",kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -870,N29,(other disorders of kidney and ureter in diseases classified elsewhere),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -871,N30,(cystitis),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -872,N31,"(neuromuscular dysfunction of bladder, not elsewhere classified)",kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -873,N32,(other disorders of bladder),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -874,N33,(bladder disorders in diseases classified elsewhere),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -875,N34,(urethritis and urethral syndrome),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -876,N35,(urethral stricture),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -877,N36,(other disorders of urethra),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -878,N37,(urethral disorders in diseases classified elsewhere),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -879,N39,(other disorders of urinary system),kidney,kidney,1.0,n00_n39,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -880,N40,(hyperplasia of prostate),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -881,N41,(inflammatory diseases of prostate),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -882,N42,(other disorders of prostate),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -883,N43,(hydrocele and spermatocele),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -884,N44,(torsion of testis),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -885,N45,(orchitis and epididymitis),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -886,N46,(male infertility),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -887,N47,"(redundant prepuce, phimosis and paraphimosis)",male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -888,N48,(other disorders of penis),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -889,N49,"(inflammatory disorders of male genital organs, not elsewhere classified)",male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -890,N50,(other disorders of male genital organs),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -891,N51,(disorders of male genital organs in diseases classified elsewhere),male_reproductive,male_reproductive,1.0,n40_n53,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -892,N60,(benign mammary dysplasia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -893,N61,(inflammatory disorders of breast),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -894,N62,(hypertrophy of breast),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -895,N63,(unspecified lump in breast),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -896,N64,(other disorders of breast),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -897,N70,(salpingitis and oophoritis),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -898,N71,"(inflammatory disease of uterus, except cervix)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -899,N72,(inflammatory disease of cervix uteri),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -900,N73,(other female pelvic inflammatory diseases),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -901,N74,(female pelvic inflammatory disorders in diseases classified elsewhere),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -902,N75,(diseases of bartholin's gland),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -903,N76,(other inflammation of vagina and vulva),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -904,N77,(vulvovaginal ulceration and inflammation in diseases classified elsewhere),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -905,N80,(endometriosis),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -906,N81,(female genital prolapse),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -907,N82,(fistulae involving female genital tract),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -908,N83,"(noninflammatory disorders of ovary, fallopian tube and broad ligament)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -909,N84,(polyp of female genital tract),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -910,N85,"(other noninflammatory disorders of uterus, except cervix)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -911,N86,(erosion and ectropion of cervix uteri),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -912,N87,(dysplasia of cervix uteri),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -913,N88,(other noninflammatory disorders of cervix uteri),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -914,N89,(other noninflammatory disorders of vagina),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -915,N90,(other noninflammatory disorders of vulva and perineum),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -916,N91,"(absent, scanty and rare menstruation)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -917,N92,"(excessive, frequent and irregular menstruation)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -918,N93,(other abnormal uterine and vaginal bleeding),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -919,N94,(pain and other conditions associated with female genital organs and menstrual cycle),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -920,N95,(menopausal and other perimenopausal disorders),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -921,N96,(habitual aborter),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -922,N97,(female infertility),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -923,N98,(complications associated with artificial fertilisation),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -924,N99,"(postprocedural disorders of genito-urinary system, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -925,O00,(ectopic pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -926,O01,(hydatidiform mole),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -927,O02,(other abnormal products of conception),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -928,O03,(spontaneous abortion),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -929,O04,(medical abortion),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -930,O05,(other abortion),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -931,O06,(unspecified abortion),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -932,O07,(failed attempted abortion),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -933,O08,(complications following abortion and ectopic and molar pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -934,O10,"(pre-existing hypertension complicating pregnancy, childbirth and the puerperium)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -935,O11,(pre-existing hypertensive disorder with superimposed proteinuria),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -936,O12,(gestational [pregnancy-induced] oedema and proteinuria without hypertension),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -937,O13,(gestational [pregnancy-induced] hypertension without significant proteinuria),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -938,O14,(gestational [pregnancy-induced] hypertension with significant proteinuria),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -939,O15,(eclampsia),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -940,O16,(unspecified maternal hypertension),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -941,O20,(haemorrhage in early pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -942,O21,(excessive vomiting in pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -943,O22,(venous complications in pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -944,O23,(infections of genito-urinary tract in pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -945,O24,(diabetes mellitus in pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -946,O25,(malnutrition in pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -947,O26,(maternal care for other conditions predominantly related to pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -948,O28,(abnormal findings on antenatal screening of mother),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -949,O29,(complications of anaesthesia during pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -950,O30,(multiple gestation),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -951,O31,(complications specific to multiple gestation),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -952,O32,(maternal care for known or suspected malpresentation of foetus),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -953,O33,(maternal care for known or suspected disproportion),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -954,O34,(maternal care for known or suspected abnormality of pelvic organs),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -955,O35,(maternal care for known or suspected foetal abnormality and damage),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -956,O36,(maternal care for other known or suspected foetal problems),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -957,O40,(polyhydramnios),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -958,O41,(other disorders of amniotic fluid and membranes),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -959,O42,(premature rupture of membranes),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -960,O43,(placental disorders),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -961,O44,(placenta praevia),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -962,O45,(premature separation of placenta [abruptio placentae]),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -963,O46,"(antepartum haemorrhage, not elsewhere classified)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -964,O47,(false labour),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -965,O48,(prolonged pregnancy),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -966,O60,(preterm delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -967,O61,(failed induction of labour),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -968,O62,(abnormalities of forces of labour),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -969,O63,(long labour),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -970,O64,(obstructed labour due to malposition and malpresentation of foetus),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -971,O65,(obstructed labour due to maternal pelvic abnormality),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -972,O66,(other obstructed labour),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -973,O67,"(labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -974,O68,(labour and delivery complicated by foetal stress [distress]),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -975,O69,(labour and delivery complicated by umbilical cord complications),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -976,O70,(perineal laceration during delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -977,O71,(other obstetric trauma),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -978,O72,(postpartum haemorrhage),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -979,O73,"(retained placenta and membranes, without haemorrhage)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -980,O74,(complications of anaesthesia during labour and delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -981,O75,"(other complications of labour and delivery, not elsewhere classified)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -982,O80,(single spontaneous delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -983,O81,(single delivery by forceps and vacuum extractor),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -984,O82,(single delivery by caesarean section),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -985,O83,(other assisted single delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -986,O84,(multiple delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -987,O85,(puerperal sepsis),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -988,O86,(other puerperal infections),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -989,O87,(venous complications in the puerperium),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -990,O88,(obstetric embolism),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -991,O89,(complications of anaesthesia during the puerperium),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -992,O90,"(complications of the puerperium, not elsewhere classified)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -993,O91,(infections of breast associated with childbirth),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -994,O92,(other disorders of breast and lactation associated with childbirth),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -995,O94,"(sequelae of complication of pregnancy, childbirth and the puerperium)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -996,O96,(death from any obstetric cause occurring more than 42 days but less than one year after delivery),female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -997,O98,"(maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -998,O99,"(other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium)",female_reproductive,female_reproductive,1.0,n70_n98_o00_o99,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -999,P00,(foetus and newborn affected by maternal conditions that may be unrelated to present pregnancy),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1000,P02,"(foetus and newborn affected by complications of placenta, cord and membranes)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1001,P03,(foetus and newborn affected by other complications of labour and delivery),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1002,P04,(foetus and newborn affected by noxious influences transmitted via placenta or breast milk),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1003,P05,(slow foetal growth and foetal malnutrition),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1004,P07,"(disorders related to short gestation and low birth weight, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1005,P08,(disorders related to long gestation and high birth weight),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1006,P10,(intracranial laceration and haemorrhage due to birth injury),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1007,P11,(other birth injuries to central nervous system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1008,P12,(birth injury to scalp),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1009,P13,(birth injury to skeleton),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1010,P14,(birth injury to peripheral nervous system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1011,P15,(other birth injuries),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1012,P20,(intra-uterine hypoxia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1013,P21,(birth asphyxia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1014,P22,(respiratory distress of newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1015,P23,(congenital pneumonia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1016,P24,(neonatal aspiration syndromes),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1017,P25,(interstitial emphysema and related conditions originating in the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1018,P26,(pulmonary haemorrhage originating in the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1019,P27,(chronic respiratory disease originating in the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1020,P28,(other respiratory conditions originating in the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1021,P29,(cardiovascular disorders originating in the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1022,P35,(congenital viral diseases),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1023,P36,(bacterial sepsis of newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1024,P37,(other congenital infectious and parasitic diseases),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1025,P38,(omphalitis of newborn with or without mild haemorrhage),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1026,P39,(other infections specific to the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1027,P50,(foetal blood loss),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1028,P51,(umbilical haemorrhage of newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1029,P52,(intracranial nontraumatic haemorrhage of foetus and newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1030,P53,(haemorrhagic disease of foetus and newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1031,P54,(other neonatal haemorrhages),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1032,P55,(haemolytic disease of foetus and newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1033,P58,(neonatal jaundice due to other excessive haemolysis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1034,P59,(neonatal jaundice from other and unspecified causes),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1035,P61,(other perinatal haematological disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1036,P70,(transitory disorders of carbohydrate metabolism specific to foetus and newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1037,P71,(transitory neonatal disorders of calcium and magnesium metabolism),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1038,P78,(other perinatal digestive system disorders),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1039,P83,(other conditions of integument specific to foetus and newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1040,P91,(other disturbances of cerebral status of newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1041,P92,(feeding problems of newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1042,P94,(disorders of muscle tone of newborn),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1043,P95,(foetal death of unspecified cause),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1044,P96,(other conditions originating in the perinatal period),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1045,Q00,(anencephaly and similar malformations),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1046,Q01,(encephalocele),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1047,Q02,(microcephaly),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1048,Q03,(congenital hydrocephalus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1049,Q04,(other congenital malformations of brain),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1050,Q05,(spina bifida),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1051,Q06,(other congenital malformations of spinal cord),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1052,Q07,(other congenital malformations of nervous system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1053,Q10,"(congenital malformations of eyelid, lachrymal apparatus and orbit)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1054,Q11,"(anophthalmos, microphthalmos and macrophthalmos)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1055,Q12,(congenital lens malformations),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1056,Q13,(congenital malformations of anterior segment of eye),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1057,Q14,(congenital malformations of posterior segment of eye),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1058,Q15,(other congenital malformations of eye),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1059,Q16,(congenital malformations of ear causing impairment of hearing),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1060,Q17,(other congenital malformations of ear),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1061,Q18,(other congenital malformations of face and neck),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1062,Q20,(congenital malformations of cardiac chambers and connexions),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1063,Q21,(congenital malformations of cardiac septa),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1064,Q22,(congenital malformations of pulmonary and tricuspid valves),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1065,Q23,(congenital malformations of aortic and mitral valves),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1066,Q24,(other congenital malformations of heart),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1067,Q25,(congenital malformations of great arteries),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1068,Q26,(congenital malformations of great veins),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1069,Q27,(other congenital malformations of peripheral vascular system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1070,Q28,(other congenital malformations of circulatory system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1071,Q30,(congenital malformations of nose),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1072,Q31,(congenital malformations of larynx),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1073,Q32,(congenital malformations of trachea and bronchus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1074,Q33,(congenital malformations of lung),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1075,Q34,(other congenital malformations of respiratory system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1076,Q35,(cleft palate),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1077,Q36,(cleft lip),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1078,Q37,(cleft palate with cleft lip),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1079,Q38,"(other congenital malformations of tongue, mouth and pharynx)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1080,Q39,(congenital malformations of oesophagus),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1081,Q40,(other congenital malformations of upper alimentary tract),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1082,Q41,"(congenital absence, atresia and stenosis of small intestine)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1083,Q42,"(congenital absence, atresia and stenosis of large intestine)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1084,Q43,(other congenital malformations of intestine),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1085,Q44,"(congenital malformations of gallbladder, bile ducts and liver)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1086,Q45,(other congenital malformations of digestive system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1087,Q50,"(congenital malformations of ovaries, fallopian tubes and broad ligaments)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1088,Q51,(congenital malformations of uterus and cervix),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1089,Q52,(other congenital malformations of female genitalia),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1090,Q53,(undescended testicle),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1091,Q54,(hypospadias),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1092,Q55,(other congenital malformations of male genital organs),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1093,Q56,(indeterminate sex and pseudohermaphroditism),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1094,Q60,(renal agenesis and other reduction defects of kidney),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1095,Q61,(cystic kidney disease),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1096,Q62,(congenital obstructive defects of renal pelvis and congenital malformations of ureter),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1097,Q63,(other congenital malformations of kidney),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1098,Q64,(other congenital malformations of urinary system),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1099,Q65,(congenital deformities of hip),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1100,Q66,(congenital deformities of feet),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1101,Q67,"(congenital musculoskeletal deformities of head, face, spine and chest)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1102,Q68,(other congenital musculoskeletal deformities),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1103,Q69,(polydactyly),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1104,Q70,(syndactyly),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1105,Q71,(reduction defects of upper limb),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1106,Q72,(reduction defects of lower limb),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1107,Q73,(reduction defects of unspecified limb),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1108,Q74,(other congenital malformations of limb(s)),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1109,Q75,(other congenital malformations of skull and face bones),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1110,Q76,(congenital malformations of spine and bony thorax),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1111,Q77,(osteochondrodysplasia with defects of growth of tubular bones and spine),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1112,Q78,(other osteochondrodysplasias),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1113,Q79,"(congenital malformations of musculoskeletal system, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1114,Q80,(congenital ichthyosis),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1115,Q81,(epidermolysis bullosa),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1116,Q82,(other congenital malformations of skin),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1117,Q83,(congenital malformations of breast),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1118,Q84,(other congenital malformations of integument),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1119,Q85,"(phakomatoses, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1120,Q86,"(congenital malformation syndromes due to known exogenous causes, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1121,Q87,(other specified congenital malformation syndromes affecting multiple systems),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1122,Q89,"(other congenital malformations, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1123,Q90,(down's syndrome),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1124,Q91,(edwards' syndrome and patau's syndrome),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1125,Q92,"(other trisomies and partial trisomies of the autosomes, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1126,Q93,"(monosomies and deletions from the autosomes, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1127,Q95,"(balanced rearrangements and structural markers, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1128,Q96,(turner's syndrome),,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1129,Q97,"(other sex chromosome abnormalities, female phenotype, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1130,Q98,"(other sex chromosome abnormalities, male phenotype, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1131,Q99,"(other chromosome abnormalities, not elsewhere classified)",,,0.0,unmapped_no_organ_rule,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1132,CXX,Unknown Cancer,,,0.0,unmapped_non_icd10,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1133,C00,Malignant neoplasm of lip,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1134,C01,Malignant neoplasm of base of tongue,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1135,C02,Malignant neoplasm of other and unspecified parts of tongue,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1136,C03,Malignant neoplasm of gum,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1137,C04,Malignant neoplasm of floor of mouth,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1138,C05,Malignant neoplasm of palate,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1139,C06,Malignant neoplasm of other and unspecified parts of mouth,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1140,C07,Malignant neoplasm of parotid gland,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1141,C08,Malignant neoplasm of other and unspecified major salivary glands,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1142,C09,Malignant neoplasm of tonsil,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1143,C10,Malignant neoplasm of oropharynx,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1144,C11,Malignant neoplasm of nasopharynx,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1145,C12,Malignant neoplasm of pyriform sinus,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1146,C13,Malignant neoplasm of hypopharynx,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1147,C14,"Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1148,C15,Malignant neoplasm of oesophagus,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1149,C16,Malignant neoplasm of stomach,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1150,C17,Malignant neoplasm of small intestine,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1151,C18,Malignant neoplasm of colon,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1152,C19,Malignant neoplasm of rectosigmoid junction,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1153,C20,Malignant neoplasm of rectum,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1154,C21,Malignant neoplasm of anus and anal canal,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1155,C22,Malignant neoplasm of liver and intrahepatic bile ducts,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1156,C23,Malignant neoplasm of gallbladder,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1157,C24,Malignant neoplasm of other and unspecified parts of biliary tract,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1158,C25,Malignant neoplasm of pancreas,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1159,C26,Malignant neoplasm of other and ill-defined digestive organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1160,C30,Malignant neoplasm of nasal cavity and middle ear,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1161,C31,Malignant neoplasm of accessory sinuses,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1162,C32,Malignant neoplasm of larynx,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1163,C33,Malignant neoplasm of trachea,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1164,C34,Malignant neoplasm of bronchus and lung,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1165,C37,Malignant neoplasm of thymus,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1166,C38,"Malignant neoplasm of heart, mediastinum and pleura",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1167,C39,Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1168,C40,Malignant neoplasm of bone and articular cartilage of limbs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1169,C41,Malignant neoplasm of bone and articular cartilage of other and unspecified sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1170,C42,hematopoietic and reticuloendothelial systems (ICD-O-3 specific),neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1171,C43,Malignant melanoma of skin,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1172,C44,Other malignant neoplasms of skin,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1173,C45,Mesothelioma,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1174,C46,Kaposi's sarcoma,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1175,C47,Malignant neoplasm of peripheral nerves and autonomic nervous system,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1176,C48,Malignant neoplasm of retroperitoneum and peritoneum,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1177,C49,Malignant neoplasm of other connective and soft tissue,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1178,C50,Malignant neoplasm of breast,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1179,C51,Malignant neoplasm of vulva,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1180,C52,Malignant neoplasm of vagina,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1181,C53,Malignant neoplasm of cervix uteri,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1182,C54,Malignant neoplasm of corpus uteri,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1183,C55,"Malignant neoplasm of uterus, part unspecified",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1184,C56,Malignant neoplasm of ovary,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1185,C57,Malignant neoplasm of other and unspecified female genital organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1186,C58,Malignant neoplasm of placenta,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1187,C60,Malignant neoplasm of penis,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1188,C61,Malignant neoplasm of prostate,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1189,C62,Malignant neoplasm of testis,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1190,C63,Malignant neoplasm of other and unspecified male genital organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1191,C64,"Malignant neoplasm of kidney, except renal pelvis",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1192,C65,Malignant neoplasm of renal pelvis,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1193,C66,Malignant neoplasm of ureter,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1194,C67,Malignant neoplasm of bladder,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1195,C68,Malignant neoplasm of other and unspecified urinary organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1196,C69,Malignant neoplasm of eye and adnexa,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1197,C70,Malignant neoplasm of meninges,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1198,C71,Malignant neoplasm of brain,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1199,C72,"Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1200,C73,Malignant neoplasm of thyroid gland,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1201,C74,Malignant neoplasm of adrenal gland,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1202,C75,Malignant neoplasm of other endocrine glands and related structures,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1203,C76,Malignant neoplasm of other and ill-defined sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1204,C77,Secondary and unspecified malignant neoplasm of lymph nodes,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1205,C78,Secondary malignant neoplasm of respiratory and digestive organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1206,C79,Secondary malignant neoplasm of other sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1207,C80,Malignant neoplasm without specification of site,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1208,C81,Hodgkin's disease,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1209,C82,Follicular [nodular] non-Hodgkin's lymphoma,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1210,C83,Diffuse non-Hodgkin's lymphoma,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1211,C84,Peripheral and cutaneous T-cell lymphomas,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1212,C85,Other and unspecified types of non-Hodgkin's lymphoma,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1213,C86,Other specified types of T/NK-cell lymphoma,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1214,C88,Malignant immunoproliferative diseases,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1215,C90,Multiple myeloma and malignant plasma cell neoplasms,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1216,C91,Lymphoid leukaemia,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1217,C92,Myeloid leukaemia,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1218,C93,Monocytic leukaemia,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1219,C94,Other leukaemias of specified cell type,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1220,C95,Leukaemia of unspecified cell type,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1221,C96,"Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1222,C97,Malignant neoplasms of independent (primary) multiple sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1223,D00,"Carcinoma in situ of oral cavity, oesophagus and stomach",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1224,D01,Carcinoma in situ of other and unspecified digestive organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1225,D02,Carcinoma in situ of middle ear and respiratory system,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1226,D03,Melanoma in situ,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1227,D04,Carcinoma in situ of skin,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1228,D05,Carcinoma in situ of breast,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1229,D06,Carcinoma in situ of cervix uteri,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1230,D07,Carcinoma in situ of other and unspecified genital organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1231,D09,Carcinoma in situ of other and unspecified sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1232,D10,Benign neoplasm of mouth and pharynx,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1233,D11,Benign neoplasm of major salivary glands,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1234,D12,"Benign neoplasm of colon, rectum, anus and anal canal",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1235,D13,Benign neoplasm of other and ill-defined parts of digestive system,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1236,D15,Benign neoplasm of other and unspecified intrathoracic organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1237,D16,Benign neoplasm of bone and articular cartilage,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1238,D18,"Haemangioma and lymphangioma, any site",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1239,D27,Benign neoplasm of ovary,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1240,D30,Benign neoplasm of urinary organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1241,D32,Benign neoplasm of meninges,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1242,D33,Benign neoplasm of brain and other parts of central nervous system,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1243,D34,Benign neoplasm of thyroid gland,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1244,D35,Benign neoplasm of other and unspecified endocrine glands,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1245,D36,Benign neoplasm of other and unspecified sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1246,D37,Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1247,D38,Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1248,D39,Neoplasm of uncertain or unknown behaviour of female genital organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1249,D40,Neoplasm of uncertain or unknown behaviour of male genital organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1250,D41,Neoplasm of uncertain or unknown behaviour of urinary organs,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1251,D42,Neoplasm of uncertain or unknown behaviour of meninges,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1252,D43,Neoplasm of uncertain or unknown behaviour of brain and central nervous system,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1253,D44,Neoplasm of uncertain or unknown behaviour of endocrine glands,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1254,D45,Polycythaemia vera,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1255,D46,Myelodysplastic syndromes,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1256,D47,"Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue",neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1257,D48,Neoplasm of uncertain or unknown behaviour of other and unspecified sites,neoplasm,neoplasm,1.0,neoplasm_c00_d48,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules -1258,DEATH,,,,0.0,unmapped_non_icd10,organ-age-inspired clinical systems based on Oh et al. Nature 2023; single-label ICD-10 rules diff --git a/plot_deephealth_index_trajectories.py b/plot_deephealth_index_trajectories.py deleted file mode 100644 index f61ca87..0000000 --- a/plot_deephealth_index_trajectories.py +++ /dev/null @@ -1,214 +0,0 @@ -from __future__ import annotations - -import argparse -from pathlib import Path - -try: - import matplotlib - - matplotlib.use("Agg") - import matplotlib.pyplot as plt -except ModuleNotFoundError as exc: - raise ModuleNotFoundError( - "plot_deephealth_index_trajectories.py requires matplotlib. " - "Install it in the server environment before running this script." - ) from exc -import numpy as np -import pandas as pd - - -REQUIRED_COLUMNS = { - "patient_id", - "sex", - "landmark_age", - "index_type", - "index_id", - "index_label", - "index_value", -} - - -def _sex_label(value: object) -> str: - text = str(value).strip().lower() - if text in {"0", "0.0", "female", "f", "woman"}: - return "female" - if text in {"1", "1.0", "male", "m", "man"}: - return "male" - return text or "unknown" - - -def _load_index_csv(path: Path) -> pd.DataFrame: - header = pd.read_csv(path, nrows=0) - missing = sorted(REQUIRED_COLUMNS - set(header.columns)) - if missing: - raise ValueError(f"{path} is missing required columns: {missing}") - df = pd.read_csv(path, usecols=sorted(REQUIRED_COLUMNS)) - df["sex_label"] = df["sex"].map(_sex_label) - df["landmark_age"] = pd.to_numeric(df["landmark_age"], errors="raise") - df["index_value"] = pd.to_numeric(df["index_value"], errors="raise") - return df - - -def _sample_patients(df: pd.DataFrame, *, n_per_sex: int, seed: int) -> dict[str, np.ndarray]: - rng = np.random.default_rng(int(seed)) - samples: dict[str, np.ndarray] = {} - for sex_label in ["female", "male"]: - ids = np.asarray(sorted(df.loc[df["sex_label"] == sex_label, "patient_id"].unique())) - if ids.size == 0: - samples[sex_label] = np.asarray([], dtype=np.int64) - continue - samples[sex_label] = np.asarray( - rng.choice(ids, size=min(int(n_per_sex), int(ids.size)), replace=False) - ) - return samples - - -def _plot_sampled_trajectories( - df: pd.DataFrame, - *, - index_type: str, - selected: dict[str, np.ndarray], - output_dir: Path, -) -> None: - sub = df[df["index_type"] == index_type].copy() - if sub.empty: - return - if index_type == "organ_involvement": - total = ( - sub.groupby(["patient_id", "sex_label", "landmark_age"], as_index=False)[ - "index_value" - ] - .mean() - .rename(columns={"index_value": "trajectory_value"}) - ) - title = "mean organ involvement" - else: - total = sub.rename(columns={"index_value": "trajectory_value"}) - title = "frailty risk" - - mean_df = ( - total.groupby(["sex_label", "landmark_age"], as_index=False)["trajectory_value"] - .mean() - .sort_values("landmark_age") - ) - - fig, ax = plt.subplots(figsize=(9.5, 5.5), dpi=160) - colors = {"female": "#b83280", "male": "#2563eb"} - for sex_label in ["female", "male"]: - for pid in selected.get(sex_label, np.asarray([], dtype=np.int64)): - one = total[total["patient_id"] == pid].sort_values("landmark_age") - if one.empty: - continue - ax.plot( - one["landmark_age"], - one["trajectory_value"], - color=colors.get(sex_label, "0.4"), - alpha=0.22, - linewidth=1.2, - ) - mean_one = mean_df[mean_df["sex_label"] == sex_label] - if not mean_one.empty: - ax.plot( - mean_one["landmark_age"], - mean_one["trajectory_value"], - color=colors.get(sex_label, "0.4"), - linewidth=2.6, - label=f"{sex_label} mean", - ) - - ax.set_title(f"{index_type}: sampled trajectories and sex-specific means") - ax.set_xlabel("Landmark age") - ax.set_ylabel(title) - ax.grid(True, alpha=0.25) - ax.legend(frameon=False) - fig.tight_layout() - fig.savefig(output_dir / f"{index_type}_sampled_trajectories_by_sex.png") - plt.close(fig) - - -def _plot_top_dimensions( - df: pd.DataFrame, - *, - output_dir: Path, - top_n: int, -) -> None: - sub = df[df["index_type"] == "organ_involvement"].copy() - if sub.empty: - return - order = ( - sub.groupby("index_id")["index_value"] - .mean() - .sort_values(ascending=False) - .head(int(top_n)) - .index.tolist() - ) - n = len(order) - if n == 0: - return - ncols = min(3, n) - nrows = int(np.ceil(n / ncols)) - fig, axes = plt.subplots(nrows, ncols, figsize=(4.0 * ncols, 3.0 * nrows), dpi=160) - axes_arr = np.asarray(axes).reshape(-1) - colors = {"female": "#b83280", "male": "#2563eb"} - for ax, index_id in zip(axes_arr, order): - one = sub[sub["index_id"] == index_id] - mean_df = ( - one.groupby(["sex_label", "landmark_age"], as_index=False)["index_value"] - .mean() - .sort_values("landmark_age") - ) - for sex_label in ["female", "male"]: - m = mean_df[mean_df["sex_label"] == sex_label] - if not m.empty: - ax.plot( - m["landmark_age"], - m["index_value"], - color=colors.get(sex_label, "0.4"), - linewidth=1.8, - label=sex_label, - ) - ax.set_title(str(index_id), fontsize=9) - ax.set_xlabel("Age") - ax.set_ylabel("Organ involvement") - ax.grid(True, alpha=0.22) - for ax in axes_arr[n:]: - ax.axis("off") - handles, labels = axes_arr[0].get_legend_handles_labels() - if handles: - fig.legend(handles, labels, loc="upper right", frameon=False) - fig.suptitle("organ_involvement: sex-specific mean trajectories for top dimensions") - fig.tight_layout(rect=(0, 0, 0.98, 0.96)) - fig.savefig(output_dir / "organ_involvement_top_dimensions_by_sex.png") - plt.close(fig) - - -def main() -> None: - parser = argparse.ArgumentParser( - description="Plot DeepHealth organ involvement and frailty risk trajectories." - ) - parser.add_argument("--input_csv", type=str, required=True) - parser.add_argument("--output_dir", type=str, default=None) - parser.add_argument("--n_per_sex", type=int, default=10) - parser.add_argument("--seed", type=int, default=2026) - parser.add_argument("--top_n", type=int, default=12) - args = parser.parse_args() - - input_csv = Path(args.input_csv) - output_dir = Path(args.output_dir) if args.output_dir else input_csv.parent - output_dir.mkdir(parents=True, exist_ok=True) - df = _load_index_csv(input_csv) - selected = _sample_patients(df, n_per_sex=int(args.n_per_sex), seed=int(args.seed)) - for index_type in ["organ_involvement", "frailty_risk"]: - _plot_sampled_trajectories( - df, - index_type=index_type, - selected=selected, - output_dir=output_dir, - ) - _plot_top_dimensions(df, output_dir=output_dir, top_n=int(args.top_n)) - print(f"Input: {input_csv}") - print(f"Output directory: {output_dir}") - - -if __name__ == "__main__": - main() diff --git a/uk_hfrs_label_mapping.csv b/uk_hfrs_label_mapping.csv deleted file mode 100644 index c49f1a3..0000000 --- a/uk_hfrs_label_mapping.csv +++ /dev/null @@ -1,1257 +0,0 @@ -token_id,label_code,label_name,hfrs_dimension_id,hfrs_dimension,hfrs_key_area,hfrs_weight,hfrs_source,match_source -3,A00,(cholera),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -4,A01,(typhoid and paratyphoid fevers),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -5,A02,(other salmonella infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -6,A03,(shigellosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -7,A04,(other bacterial intestinal infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.1,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -8,A05,(other bacterial foodborne intoxications),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -9,A06,(amoebiasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -10,A07,(other protozoal intestinal diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -11,A08,(viral and other specified intestinal infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -12,A09,(diarrhoea and gastro-enteritis of presumed infectious origin),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.1,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -13,A15,"(respiratory tuberculosis, bacteriologically and histologically confirmed)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -14,A16,"(respiratory tuberculosis, not confirmed bacteriologically or histologically)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -15,A17,(tuberculosis of nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -16,A18,(tuberculosis of other organs),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -17,A19,(miliary tuberculosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -18,A20,(plague),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -19,A22,(anthrax),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -20,A23,(brucellosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -21,A24,(glanders and melioidosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -22,A25,(rat-bite fevers),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -23,A26,(erysipeloid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -24,A27,(leptospirosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -25,A28,"(other zoonotic bacterial diseases, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -26,A30,(leprosy [hansen's disease]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -27,A31,(infection due to other mycobacteria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -28,A32,(listeriosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -29,A33,(tetanus neonatorum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -30,A35,(other tetanus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -31,A36,(diphtheria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -32,A37,(whooping cough),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -33,A38,(scarlet fever),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -34,A39,(meningococcal infection),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -35,A40,(streptococcal septicaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -36,A41,(other septicaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.6,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -37,A42,(actinomycosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -38,A43,(nocardiosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -39,A44,(bartonellosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -40,A46,(erysipelas),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -41,A48,"(other bacterial diseases, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -42,A49,(bacterial infection of unspecified site),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -43,A50,(congenital syphilis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -44,A51,(early syphilis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -45,A52,(late syphilis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -46,A53,(other and unspecified syphilis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -47,A54,(gonococcal infection),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -48,A55,(chlamydial lymphogranuloma (venereum)),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -49,A56,(other sexually transmitted chlamydial diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -50,A58,(granuloma inguinale),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -51,A59,(trichomoniasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -52,A60,(anogenital herpesviral [herpes simplex] infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -53,A63,"(other predominantly sexually transmitted diseases, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -54,A64,(unspecified sexually transmitted disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -55,A66,(yaws),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -56,A67,(pinta [carate]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -57,A68,(relapsing fevers),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -58,A69,(other spirochaetal infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -59,A70,(chlamydia psittaci infection),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -60,A71,(trachoma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -61,A74,(other diseases caused by chlamydiae),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -62,A75,(typhus fever),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -63,A77,(spotted fever [tick-borne rickettsioses]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -64,A78,(q fever),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -65,A79,(other rickettsioses),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -66,A80,(acute poliomyelitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -67,A81,(atypical virus infections of central nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -68,A82,(rabies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -69,A83,(mosquito-borne viral encephalitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -70,A84,(tick-borne viral encephalitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -71,A85,"(other viral encephalitis, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -72,A86,(unspecified viral encephalitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -73,A87,(viral meningitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -74,A88,"(other viral infections of central nervous system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -75,A89,(unspecified viral infection of central nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -76,A90,(dengue fever [classical dengue]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -77,A91,(dengue haemorrhagic fever),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -78,A92,(other mosquito-borne viral fevers),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -79,A93,"(other arthropod-borne viral fevers, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -80,A94,(unspecified arthropod-borne viral fever),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -81,A95,(yellow fever),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -82,A97,(dengue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -83,A98,"(other viral haemorrhagic fevers, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -84,B00,(herpesviral [herpes simplex] infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -85,B01,(varicella [chickenpox]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -86,B02,(zoster [herpes zoster]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -87,B03,(smallpox),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -88,B05,(measles),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -89,B06,(rubella [german measles]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -90,B07,(viral warts),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -91,B08,"(other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -92,B09,(unspecified viral infection characterised by skin and mucous membrane lesions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -93,B15,(acute hepatitis a),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -94,B16,(acute hepatitis b),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -95,B17,(other acute viral hepatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -96,B18,(chronic viral hepatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -97,B19,(unspecified viral hepatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -98,B20,(human immunodeficiency virus [hiv] disease resulting in infectious and parasitic diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -99,B21,(human immunodeficiency virus [hiv] disease resulting in malignant neoplasms),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -100,B22,(human immunodeficiency virus [hiv] disease resulting in other specified diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -101,B23,(human immunodeficiency virus [hiv] disease resulting in other conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -102,B24,(unspecified human immunodeficiency virus [hiv] disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -103,B25,(cytomegaloviral disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -104,B26,(mumps),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -105,B27,(infectious mononucleosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -106,B30,(viral conjunctivitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -107,B33,"(other viral diseases, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -108,B34,(viral infection of unspecified site),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -109,B35,(dermatophytosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -110,B36,(other superficial mycoses),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -111,B37,(candidiasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -112,B38,(coccidioidomycosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -113,B39,(histoplasmosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -114,B40,(blastomycosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -115,B42,(sporotrichosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -116,B43,(chromomycosis and phaeomycotic abscess),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -117,B44,(aspergillosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -118,B45,(cryptococcosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -119,B46,(zygomycosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -120,B47,(mycetoma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -121,B48,"(other mycoses, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -122,B49,(unspecified mycosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -123,B50,(plasmodium falciparum malaria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -124,B51,(plasmodium vivax malaria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -125,B52,(plasmodium malariae malaria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -126,B53,(other parasitologically confirmed malaria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -127,B54,(unspecified malaria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -128,B55,(leishmaniasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -129,B57,(chagas' disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -130,B58,(toxoplasmosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -131,B59,(pneumocystosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -132,B60,"(other protozoal diseases, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -133,B65,(schistosomiasis [bilharziasis]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -134,B66,(other fluke infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -135,B67,(echinococcosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -136,B68,(taeniasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -137,B69,(cysticercosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -138,B71,(other cestode infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -139,B73,(onchocerciasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -140,B74,(filariasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -141,B75,(trichinellosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -142,B76,(hookworm diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -143,B77,(ascariasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -144,B78,(strongyloidiasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -145,B79,(trichuriasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -146,B80,(enterobiasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -147,B81,"(other intestinal helminthiases, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -148,B82,(unspecified intestinal parasitism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -149,B83,(other helminthiases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -150,B85,(pediculosis and phthiriasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -151,B86,(scabies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -152,B87,(myiasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -153,B88,(other infestations),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -154,B89,(unspecified parasitic disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -155,B90,(sequelae of tuberculosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -156,B91,(sequelae of poliomyelitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -157,B94,(sequelae of other and unspecified infectious and parasitic diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -158,B95,(streptococcus and staphylococcus as the cause of diseases classified to other chapters),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.7,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -159,B96,(other bacterial agents as the cause of diseases classified to other chapters),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.9,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -160,B97,(viral agents as the cause of diseases classified to other chapters),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -161,B98,(other specified infectious agents as the cause of diseases classified to other chapters),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -162,B99,(other and unspecified infectious diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -163,D50,(iron deficiency anaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -164,D51,(vitamin b12 deficiency anaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -165,D52,(folate deficiency anaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -166,D53,(other nutritional anaemias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -167,D55,(anaemia due to enzyme disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -168,D56,(thalassaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -169,D57,(sickle-cell disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -170,D58,(other hereditary haemolytic anaemias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -171,D59,(acquired haemolytic anaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -172,D60,(acquired pure red cell aplasia [erythroblastopenia]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -173,D61,(other aplastic anaemias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -174,D62,(acute posthaemorrhagic anaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -175,D63,(anaemia in chronic diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -176,D64,(other anaemias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -177,D65,(disseminated intravascular coagulation [defibrination syndrome]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -178,D66,(hereditary factor viii deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -179,D67,(hereditary factor ix deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -180,D68,(other coagulation defects),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -181,D69,(purpura and other haemorrhagic conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -182,D70,(agranulocytosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -183,D71,(functional disorders of polymorphonuclear neutrophils),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -184,D72,(other disorders of white blood cells),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -185,D73,(diseases of spleen),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -186,D74,(methaemoglobinaemia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -187,D75,(other diseases of blood and blood-forming organs),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -188,D76,(certain diseases involving lymphoreticular tissue and reticulohistiocytic system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -189,D77,(other disorders of blood and blood-forming organs in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -190,D80,(immunodeficiency with predominantly antibody defects),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -191,D81,(combined immunodeficiencies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -192,D82,(immunodeficiency associated with other major defects),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -193,D83,(common variable immunodeficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -194,D84,(other immunodeficiencies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -195,D86,(sarcoidosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -196,D89,"(other disorders involving the immune mechanism, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -197,E01,(iodine-deficiency-related thyroid disorders and allied conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -198,E02,(subclinical iodine-deficiency hypothyroidism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -199,E03,(other hypothyroidism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -200,E04,(other non-toxic goitre),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -201,E05,(thyrotoxicosis [hyperthyroidism]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.9,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -202,E06,(thyroiditis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -203,E07,(other disorders of thyroid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -204,E10,(insulin-dependent diabetes mellitus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -205,E11,(non-insulin-dependent diabetes mellitus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -206,E12,(malnutrition-related diabetes mellitus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -207,E13,(other specified diabetes mellitus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -208,E14,(unspecified diabetes mellitus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -209,E15,(nondiabetic hypoglycaemic coma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -210,E16,(other disorders of pancreatic internal secretion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -211,E20,(hypoparathyroidism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -212,E21,(hyperparathyroidism and other disorders of parathyroid gland),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -213,E22,(hyperfunction of pituitary gland),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -214,E23,(hypofunction and other disorders of pituitary gland),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -215,E24,(cushing's syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -216,E25,(adrenogenital disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -217,E26,(hyperaldosteronism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -218,E27,(other disorders of adrenal gland),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -219,E28,(ovarian dysfunction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -220,E29,(testicular dysfunction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -221,E30,"(disorders of puberty, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -222,E31,(polyglandular dysfunction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -223,E32,(diseases of thymus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -224,E34,(other endocrine disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -225,E35,(disorders of endocrine glands in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -226,E41,(nutritional marasmus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -227,E43,(unspecified severe protein-energy malnutrition),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -228,E44,(protein-energy malnutrition of moderate and mild degree),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -229,E45,(retarded development following protein-energy malnutrition),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -230,E46,(unspecified protein-energy malnutrition),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -231,E50,(vitamin a deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -232,E51,(thiamine deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -233,E52,(niacin deficiency [pellagra]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -234,E53,(deficiency of other b group vitamins),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.9,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -235,E54,(ascorbic acid deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -236,E55,(vitamin d deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -237,E56,(other vitamin deficiencies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -238,E58,(dietary calcium deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -239,E59,(dietary selenium deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -240,E60,(dietary zinc deficiency),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -241,E61,(deficiency of other nutrient elements),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -242,E63,(other nutritional deficiencies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -243,E64,(sequelae of malnutrition and other nutritional deficiencies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -244,E65,(localised adiposity),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -245,E66,(obesity),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -246,E67,(other hyperalimentation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -247,E68,(sequelae of hyperalimentation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -248,E70,(disorders of aromatic amino-acid metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -249,E71,(disorders of branched-chain amino-acid metabolism and fatty-acid metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -250,E72,(other disorders of amino-acid metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -251,E73,(lactose intolerance),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -252,E74,(other disorders of carbohydrate metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -253,E75,(disorders of sphingolipid metabolism and other lipid storage disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -254,E76,(disorders of glycosaminoglycan metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -255,E77,(disorders of glycoprotein metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -256,E78,(disorders of lipoprotein metabolism and other lipidaemias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -257,E79,(disorders of purine and pyrimidine metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -258,E80,(disorders of porphyrin and bilirubin metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -259,E83,(disorders of mineral metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -260,E84,(cystic fibrosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -261,E85,(amyloidosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -262,E86,(volume depletion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.3,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -263,E87,"(other disorders of fluid, electrolyte and acid-base balance)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.3,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -264,E88,(other metabolic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -265,E89,"(postprocedural endocrine and metabolic disorders, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -266,F00,(dementia in alzheimer's disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,7.1,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -267,F01,(vascular dementia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -268,F02,(dementia in other diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -269,F03,(unspecified dementia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.1,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -270,F04,"(organic amnesic syndrome, not induced by alcohol and other psychoactive substances)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -271,F05,"(delirium, not induced by alcohol and other psychoactive substances)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,3.2,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -272,F06,(other mental disorders due to brain damage and dysfunction and to physical disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -273,F07,"(personality and behavioural disorders due to brain disease, damage and dysfunction)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -274,F09,(unspecified organic or symptomatic mental disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -275,F10,(mental and behavioural disorders due to use of alcohol),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.7,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -276,F11,(mental and behavioural disorders due to use of opioids),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -277,F12,(mental and behavioural disorders due to use of cannabinoids),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -278,F13,(mental and behavioural disorders due to use of sedatives or hypnotics),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -279,F14,(mental and behavioural disorders due to use of cocaine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -280,F15,"(mental and behavioural disorders due to use of other stimulants, including caffeine)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -281,F16,(mental and behavioural disorders due to use of hallucinogens),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -282,F17,(mental and behavioural disorders due to use of tobacco),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -283,F18,(mental and behavioural disorders due to use of volatile solvents),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -284,F19,(mental and behavioural disorders due to multiple drug use and use of other psychoactive substances),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -285,F20,(schizophrenia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -286,F21,(schizotypal disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -287,F22,(persistent delusional disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -288,F23,(acute and transient psychotic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -289,F24,(induced delusional disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -290,F25,(schizoaffective disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -291,F28,(other nonorganic psychotic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -292,F29,(unspecified nonorganic psychosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -293,F30,(manic episode),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -294,F31,(bipolar affective disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -295,F32,(depressive episode),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.5,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -296,F33,(recurrent depressive disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -297,F34,(persistent mood [affective] disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -298,F38,(other mood [affective] disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -299,F39,(unspecified mood [affective] disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -300,F40,(phobic anxiety disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -301,F41,(other anxiety disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -302,F42,(obsessive-compulsive disorder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -303,F43,"(reaction to severe stress, and adjustment disorders)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -304,F44,(dissociative [conversion] disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -305,F45,(somatoform disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -306,F48,(other neurotic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -307,F50,(eating disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -308,F51,(nonorganic sleep disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -309,F52,"(sexual dysfunction, not caused by organic disorder or disease)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -310,F53,"(mental and behavioural disorders associated with the puerperium, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -311,F54,(psychological and behavioural factors associated with disorders or diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -312,F55,(abuse of non-dependence-producing substances),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -313,F59,(unspecified behavioural syndromes associated with physiological disturbances and physical factors),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -314,F60,(specific personality disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -315,F61,(mixed and other personality disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -316,F62,"(enduring personality changes, not attributable to brain damage and disease)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -317,F63,(habit and impulse disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -318,F64,(gender identity disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -319,F65,(disorders of sexual preference),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -320,F66,(psychological and behavioural disorders associated with sexual development and orientation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -321,F68,(other disorders of adult personality and behaviour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -322,F69,(unspecified disorder of adult personality and behaviour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -323,F70,(mild mental retardation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -324,F71,(moderate mental retardation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -325,F72,(severe mental retardation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -326,F78,(other mental retardation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -327,F79,(unspecified mental retardation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -328,F80,(specific developmental disorders of speech and language),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -329,F81,(specific developmental disorders of scholastic skills),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -330,F82,(specific developmental disorder of motor function),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -331,F83,(mixed specific developmental disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -332,F84,(pervasive developmental disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -333,F88,(other disorders of psychological development),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -334,F89,(unspecified disorder of psychological development),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -335,F90,(hyperkinetic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -336,F91,(conduct disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -337,F92,(mixed disorders of conduct and emotions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -338,F93,(emotional disorders with onset specific to childhood),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -339,F94,(disorders of social functioning with onset specific to childhood and adolescence),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -340,F95,(tic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -341,F98,(other behavioural and emotional disorders with onset usually occurring in childhood and adolescence),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -342,F99,"(mental disorder, not otherwise specified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -343,G00,"(bacterial meningitis, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -344,G01,(meningitis in bacterial diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -345,G02,(meningitis in other infectious and parasitic diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -346,G03,(meningitis due to other and unspecified causes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -347,G04,"(encephalitis, myelitis and encephalomyelitis)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -348,G05,"(encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -349,G06,(intracranial and intraspinal abscess and granuloma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -350,G07,(intracranial and intraspinal abscess and granuloma in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -351,G08,(intracranial and intraspinal phlebitis and thrombophlebitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -352,G09,(sequelae of inflammatory diseases of central nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -353,G10,(huntington's disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -354,G11,(hereditary ataxia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -355,G12,(spinal muscular atrophy and related syndromes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -356,G13,(systemic atrophies primarily affecting central nervous system in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -357,G14,(postpolio syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -358,G20,(parkinson's disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.8,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -359,G21,(secondary parkinsonism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -360,G22,(parkinsonism in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -361,G23,(other degenerative diseases of basal ganglia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -362,G24,(dystonia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -363,G25,(other extrapyramidal and movement disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -364,G30,(alzheimer's disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,4.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -365,G31,"(other degenerative diseases of nervous system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.2,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -366,G32,(other degenerative disorders of nervous system in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -367,G35,(multiple sclerosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -368,G36,(other acute disseminated demyelination),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -369,G37,(other demyelinating diseases of central nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -370,G40,(epilepsy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.5,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -371,G41,(status epilepticus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -372,G43,(migraine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -373,G44,(other headache syndromes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -374,G45,(transient cerebral ischaemic attacks and related syndromes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.2,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -375,G46,(vascular syndromes of brain in cerebrovascular diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -376,G47,(sleep disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -377,G50,(disorders of trigeminal nerve),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -378,G51,(facial nerve disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -379,G52,(disorders of other cranial nerves),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -380,G53,(cranial nerve disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -381,G54,(nerve root and plexus disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -382,G55,(nerve root and plexus compressions in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -383,G56,(mononeuropathies of upper limb),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -384,G57,(mononeuropathies of lower limb),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -385,G58,(other mononeuropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -386,G59,(mononeuropathy in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -387,G60,(hereditary and idiopathic neuropathy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -388,G61,(inflammatory polyneuropathy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -389,G62,(other polyneuropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -390,G63,(polyneuropathy in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -391,G64,(other disorders of peripheral nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -392,G70,(myasthenia gravis and other myoneural disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -393,G71,(primary disorders of muscles),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -394,G72,(other myopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -395,G73,(disorders of myoneural junction and muscle in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -396,G80,(infantile cerebral palsy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -397,G81,(hemiplegia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,4.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -398,G82,(paraplegia and tetraplegia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -399,G83,(other paralytic syndromes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -400,G90,(disorders of autonomic nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -401,G91,(hydrocephalus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -402,G92,(toxic encephalopathy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -403,G93,(other disorders of brain),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -404,G94,(other disorders of brain in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -405,G95,(other diseases of spinal cord),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -406,G96,(other disorders of central nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -407,G97,"(postprocedural disorders of nervous system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -408,G98,"(other disorders of nervous system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -409,G99,(other disorders of nervous system in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -410,H00,(hordeolum and chalazion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -411,H01,(other inflammation of eyelid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -412,H02,(other disorders of eyelid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -413,H03,(disorders of eyelid in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -414,H04,(disorders of lachrymal system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -415,H05,(disorders of orbit),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -416,H06,(disorders of lachrymal system and orbit in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -417,H10,(conjunctivitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -418,H11,(other disorders of conjunctiva),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -419,H13,(disorders of conjunctiva in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -420,H15,(disorders of sclera),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -421,H16,(keratitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -422,H17,(corneal scars and opacities),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -423,H18,(other disorders of cornea),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -424,H19,(disorders of sclera and cornea in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -425,H20,(iridocyclitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -426,H21,(other disorders of iris and ciliary body),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -427,H22,(disorders of iris and ciliary body in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -428,H25,(senile cataract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -429,H26,(other cataract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -430,H27,(other disorders of lens),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -431,H28,(cataract and other disorders of lens in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -432,H30,(chorioretinal inflammation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -433,H31,(other disorders of choroid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -434,H32,(chorioretinal disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -435,H33,(retinal detachments and breaks),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -436,H34,(retinal vascular occlusions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -437,H35,(other retinal disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -438,H36,(retinal disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -439,H40,(glaucoma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -440,H42,(glaucoma in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -441,H43,(disorders of vitreous body),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -442,H44,(disorders of globe),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -443,H45,(disorders of vitreous body and globe in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -444,H46,(optic neuritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -445,H47,(other disorders of optic [2nd] nerve and visual pathways),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -446,H48,(disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -447,H49,(paralytic strabismus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -448,H50,(other strabismus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -449,H51,(other disorders of binocular movement),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -450,H52,(disorders of refraction and accommodation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -451,H53,(visual disturbances),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -452,H54,(blindness and low vision),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.9,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -453,H55,(nystagmus and other irregular eye movements),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -454,H57,(other disorders of eye and adnexa),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -455,H58,(other disorders of eye and adnexa in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -456,H59,"(postprocedural disorders of eye and adnexa, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -457,H60,(otitis externa),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -458,H61,(other disorders of external ear),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -459,H62,(disorders of external ear in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -460,H65,(nonsuppurative otitis media),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -461,H66,(suppurative and unspecified otitis media),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -462,H67,(otitis media in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -463,H68,(eustachian salpingitis and obstruction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -464,H69,(other disorders of eustachian tube),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -465,H70,(mastoiditis and related conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -466,H71,(cholesteatoma of middle ear),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -467,H72,(perforation of tympanic membrane),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -468,H73,(other disorders of tympanic membrane),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -469,H74,(other disorders of middle ear and mastoid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -470,H75,(other disorders of middle ear and mastoid in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -471,H80,(otosclerosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -472,H81,(disorders of vestibular function),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -473,H82,(vertiginous syndromes in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -474,H83,(other diseases of inner ear),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -475,H90,(conductive and sensorineural hearing loss),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -476,H91,(other hearing loss),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.9,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -477,H92,(otalgia and effusion of ear),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -478,H93,"(other disorders of ear, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -479,H94,(other disorders of ear in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -480,H95,"(postprocedural disorders of ear and mastoid process, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -481,I00,(rheumatic fever without mention of heart involvement),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -482,I01,(rheumatic fever with heart involvement),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -483,I02,(rheumatic chorea),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -484,I05,(rheumatic mitral valve diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -485,I06,(rheumatic aortic valve diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -486,I07,(rheumatic tricuspid valve diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -487,I08,(multiple valve diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -488,I09,(other rheumatic heart diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -489,I10,(essential (primary) hypertension),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -490,I11,(hypertensive heart disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -491,I12,(hypertensive renal disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -492,I13,(hypertensive heart and renal disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -493,I15,(secondary hypertension),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -494,I20,(angina pectoris),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -495,I21,(acute myocardial infarction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -496,I22,(subsequent myocardial infarction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -497,I23,(certain current complications following acute myocardial infarction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -498,I24,(other acute ischaemic heart diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -499,I25,(chronic ischaemic heart disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -500,I26,(pulmonary embolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -501,I27,(other pulmonary heart diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -502,I28,(other diseases of pulmonary vessels),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -503,I30,(acute pericarditis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -504,I31,(other diseases of pericardium),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -505,I32,(pericarditis in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -506,I33,(acute and subacute endocarditis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -507,I34,(nonrheumatic mitral valve disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -508,I35,(nonrheumatic aortic valve disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -509,I36,(nonrheumatic tricuspid valve disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -510,I37,(pulmonary valve disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -511,I38,"(endocarditis, valve unspecified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -512,I39,(endocarditis and heart valve disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -513,I40,(acute myocarditis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -514,I41,(myocarditis in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -515,I42,(cardiomyopathy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -516,I43,(cardiomyopathy in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -517,I44,(atrioventricular and left bundle-branch block),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -518,I45,(other conduction disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -519,I46,(cardiac arrest),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -520,I47,(paroxysmal tachycardia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -521,I48,(atrial fibrillation and flutter),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -522,I49,(other cardiac arrhythmias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -523,I50,(heart failure),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -524,I51,(complications and ill-defined descriptions of heart disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -525,I52,(other heart disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -526,I60,(subarachnoid haemorrhage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -527,I61,(intracerebral haemorrhage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -528,I62,(other nontraumatic intracranial haemorrhage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -529,I63,(cerebral infarction),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.8,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -530,I64,"(stroke, not specified as haemorrhage or infarction)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -531,I65,"(occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -532,I66,"(occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -533,I67,(other cerebrovascular diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.6,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -534,I68,(cerebrovascular disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -535,I69,(sequelae of cerebrovascular disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,3.7,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -536,I70,(atherosclerosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -537,I71,(aortic aneurysm and dissection),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -538,I72,(other aneurysm),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -539,I73,(other peripheral vascular diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -540,I74,(arterial embolism and thrombosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -541,I77,(other disorders of arteries and arterioles),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -542,I78,(diseases of capillaries),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -543,I79,"(disorders of arteries, arterioles and capillaries in diseases classified elsewhere)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -544,I80,(phlebitis and thrombophlebitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -545,I81,(portal vein thrombosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -546,I82,(other venous embolism and thrombosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -547,I83,(varicose veins of lower extremities),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -548,I84,(haemorrhoids),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -549,I85,(oesophageal varices),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -550,I86,(varicose veins of other sites),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -551,I87,(other disorders of veins),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -552,I88,(nonspecific lymphadenitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -553,I89,(other non-infective disorders of lymphatic vessels and lymph nodes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -554,I95,(hypotension),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.6,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -555,I97,"(postprocedural disorders of circulatory system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -556,I98,(other disorders of circulatory system in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -557,I99,(other and unspecified disorders of circulatory system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -558,J00,(acute nasopharyngitis [common cold]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -559,J01,(acute sinusitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -560,J02,(acute pharyngitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -561,J03,(acute tonsillitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -562,J04,(acute laryngitis and tracheitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -563,J05,(acute obstructive laryngitis [croup] and epiglottitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -564,J06,(acute upper respiratory infections of multiple and unspecified sites),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -565,J09,(influenza due to certain identified influenza virus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -566,J10,(influenza due to identified influenza virus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -567,J11,"(influenza, virus not identified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -568,J12,"(viral pneumonia, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -569,J13,(pneumonia due to streptococcus pneumoniae),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -570,J14,(pneumonia due to haemophilus influenzae),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -571,J15,"(bacterial pneumonia, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -572,J16,"(pneumonia due to other infectious organisms, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -573,J17,(pneumonia in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -574,J18,"(pneumonia, organism unspecified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.1,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -575,J20,(acute bronchitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -576,J21,(acute bronchiolitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -577,J22,(unspecified acute lower respiratory infection),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.7,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -578,J30,(vasomotor and allergic rhinitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -579,J31,"(chronic rhinitis, nasopharyngitis and pharyngitis)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -580,J32,(chronic sinusitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -581,J33,(nasal polyp),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -582,J34,(other disorders of nose and nasal sinuses),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -583,J35,(chronic diseases of tonsils and adenoids),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -584,J36,(peritonsillar abscess),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -585,J37,(chronic laryngitis and laryngotracheitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -586,J38,"(diseases of vocal cords and larynx, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -587,J39,(other diseases of upper respiratory tract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -588,J40,"(bronchitis, not specified as acute or chronic)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -589,J41,(simple and mucopurulent chronic bronchitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -590,J42,(unspecified chronic bronchitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -591,J43,(emphysema),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -592,J44,(other chronic obstructive pulmonary disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -593,J45,(asthma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -594,J46,(status asthmaticus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -595,J47,(bronchiectasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -596,J60,(coalworker's pneumoconiosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -597,J61,(pneumoconiosis due to asbestos and other mineral fibres),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -598,J62,(pneumoconiosis due to dust containing silica),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -599,J63,(pneumoconiosis due to other inorganic dusts),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -600,J64,(unspecified pneumoconiosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -601,J66,(airway disease due to specific organic dust),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -602,J67,(hypersensitivity pneumonitis due to organic dust),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -603,J68,"(respiratory conditions due to inhalation of chemicals, gases, fumes and vapours)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -604,J69,(pneumonitis due to solids and liquids),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -605,J70,(respiratory conditions due to other external agents),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -606,J80,(adult respiratory distress syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -607,J81,(pulmonary oedema),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -608,J82,"(pulmonary eosinophilia, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -609,J84,(other interstitial pulmonary diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -610,J85,(abscess of lung and mediastinum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -611,J86,(pyothorax),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -612,J90,"(pleural effusion, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -613,J91,(pleural effusion in conditions classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -614,J92,(pleural plaque),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -615,J93,(pneumothorax),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -616,J94,(other pleural conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -617,J95,"(postprocedural respiratory disorders, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -618,J96,"(respiratory failure, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.5,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -619,J98,(other respiratory disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -620,J99,(respiratory disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -621,K00,(disorders of tooth development and eruption),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -622,K01,(embedded and impacted teeth),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -623,K02,(dental caries),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -624,K03,(other diseases of hard tissues of teeth),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -625,K04,(diseases of pulp and periapical tissues),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -626,K05,(gingivitis and periodontal diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -627,K06,(other disorders of gingiva and edentulous alveolar ridge),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -628,K07,(dentofacial anomalies [including malocclusion]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -629,K08,(other disorders of teeth and supporting structures),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -630,K09,"(cysts of oral region, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -631,K10,(other diseases of jaws),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -632,K11,(diseases of salivary glands),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -633,K12,(stomatitis and related lesions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -634,K13,(other diseases of lip and oral mucosa),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -635,K14,(diseases of tongue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -636,K20,(oesophagitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -637,K21,(gastro-oesophageal reflux disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -638,K22,(other diseases of oesophagus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -639,K23,(disorders of oesophagus in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -640,K25,(gastric ulcer),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -641,K26,(duodenal ulcer),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.6,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -642,K27,"(peptic ulcer, site unspecified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -643,K28,(gastrojejunal ulcer),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -644,K29,(gastritis and duodenitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -645,K30,(dyspepsia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -646,K31,(other diseases of stomach and duodenum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -647,K35,(acute appendicitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -648,K36,(other appendicitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -649,K37,(unspecified appendicitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -650,K38,(other diseases of appendix),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -651,K40,(inguinal hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -652,K41,(femoral hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -653,K42,(umbilical hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -654,K43,(ventral hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -655,K44,(diaphragmatic hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -656,K45,(other abdominal hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -657,K46,(unspecified abdominal hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -658,K50,(crohn's disease [regional enteritis]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -659,K51,(ulcerative colitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -660,K52,(other non-infective gastro-enteritis and colitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.3,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -661,K55,(vascular disorders of intestine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -662,K56,(paralytic ileus and intestinal obstruction without hernia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -663,K57,(diverticular disease of intestine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -664,K58,(irritable bowel syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -665,K59,(other functional intestinal disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.8,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -666,K60,(fissure and fistula of anal and rectal regions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -667,K61,(abscess of anal and rectal regions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -668,K62,(other diseases of anus and rectum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -669,K63,(other diseases of intestine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -670,K64,(haemorrhoids and perianal venous thrombosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -671,K65,(peritonitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -672,K66,(other disorders of peritoneum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -673,K67,(disorders of peritoneum in infectious diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -674,K70,(alcoholic liver disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -675,K71,(toxic liver disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -676,K72,"(hepatic failure, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -677,K73,"(chronic hepatitis, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -678,K74,(fibrosis and cirrhosis of liver),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -679,K75,(other inflammatory liver diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -680,K76,(other diseases of liver),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -681,K77,(liver disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -682,K80,(cholelithiasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -683,K81,(cholecystitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -684,K82,(other diseases of gallbladder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -685,K83,(other diseases of biliary tract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -686,K85,(acute pancreatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -687,K86,(other diseases of pancreas),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -688,K87,"(disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -689,K90,(intestinal malabsorption),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -690,K91,"(postprocedural disorders of digestive system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -691,K92,(other diseases of digestive system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.8,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -692,K93,(disorders of other digestive organs in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -693,L00,(staphylococcal scalded skin syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -694,L01,(impetigo),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -695,L02,"(cutaneous abscess, furuncle and carbuncle)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -696,L03,(cellulitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -697,L04,(acute lymphadenitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -698,L05,(pilonidal cyst),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -699,L08,(other local infections of skin and subcutaneous tissue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -700,L10,(pemphigus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -701,L11,(other acantholytic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -702,L12,(pemphigoid),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -703,L13,(other bullous disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -704,L14,(bullous disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -705,L20,(atopic dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -706,L21,(seborrhoeic dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -707,L22,(diaper [napkin] dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -708,L23,(allergic contact dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -709,L24,(irritant contact dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -710,L25,(unspecified contact dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -711,L26,(exfoliative dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -712,L27,(dermatitis due to substances taken internally),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -713,L28,(lichen simplex chronicus and prurigo),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -714,L29,(pruritus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -715,L30,(other dermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -716,L40,(psoriasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -717,L41,(parapsoriasis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -718,L42,(pityriasis rosea),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -719,L43,(lichen planus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -720,L44,(other papulosquamous disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -721,L50,(urticaria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -722,L51,(erythema multiforme),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -723,L52,(erythema nodosum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -724,L53,(other erythematous conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -725,L54,(erythema in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -726,L55,(sunburn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -727,L56,(other acute skin changes due to ultraviolet radiation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -728,L57,(skin changes due to chronic exposure to nonionising radiation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -729,L58,(radiodermatitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -730,L59,(other disorders of skin and subcutaneous tissue related to radiation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -731,L60,(nail disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -732,L62,(nail disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -733,L63,(alopecia areata),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -734,L64,(androgenic alopecia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -735,L65,(other nonscarring hair loss),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -736,L66,(cicatricial alopecia [scarring hair loss]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -737,L67,(hair colour and hair shaft abnormalities),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -738,L68,(hypertrichosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -739,L70,(acne),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -740,L71,(rosacea),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -741,L72,(follicular cysts of skin and subcutaneous tissue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -742,L73,(other follicular disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -743,L74,(eccrine sweat disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -744,L75,(apocrine sweat disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -745,L80,(vitiligo),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -746,L81,(other disorders of pigmentation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -747,L82,(seborrhoeic keratosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -748,L83,(acanthosis nigricans),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -749,L84,(corns and callosities),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -750,L85,(other epidermal thickening),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -751,L86,(keratoderma in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -752,L87,(transepidermal elimination disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -753,L88,(pyoderma gangrenosum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -754,L89,(decubitus ulcer),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.7,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -755,L90,(atrophic disorders of skin),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -756,L91,(hypertrophic disorders of skin),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -757,L92,(granulomatous disorders of skin and subcutaneous tissue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -758,L93,(lupus erythematosus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -759,L94,(other localised connective tissue disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -760,L95,"(vasculitis limited to skin, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -761,L97,"(ulcer of lower limb, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.6,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -762,L98,"(other disorders of skin and subcutaneous tissue, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -763,L99,(other disorders of skin and subcutaneous tissue in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -764,M00,(pyogenic arthritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -765,M01,(direct infections of joint in infectious and parasitic diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -766,M02,(reactive arthropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -767,M03,(postinfective and reactive arthropathies in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -768,M05,(seropositive rheumatoid arthritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -769,M06,(other rheumatoid arthritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -770,M07,(psoriatic and enteropathic arthropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -771,M08,(juvenile arthritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -772,M09,(juvenile arthritis in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -773,M10,(gout),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -774,M11,(other crystal arthropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -775,M12,(other specific arthropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -776,M13,(other arthritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -777,M14,(arthropathies in other diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -778,M15,(polyarthrosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -779,M16,(coxarthrosis [arthrosis of hip]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -780,M17,(gonarthrosis [arthrosis of knee]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -781,M18,(arthrosis of first carpometacarpal joint),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -782,M19,(other arthrosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.5,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -783,M20,(acquired deformities of fingers and toes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -784,M21,(other acquired deformities of limbs),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -785,M22,(disorders of patella),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -786,M23,(internal derangement of knee),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -787,M24,(other specific joint derangements),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -788,M25,"(other joint disorders, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,2.3,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -789,M30,(polyarteritis nodosa and related conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -790,M31,(other necrotising vasculopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -791,M32,(systemic lupus erythematosus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -792,M33,(dermatopolymyositis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -793,M34,(systemic sclerosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -794,M35,(other systemic involvement of connective tissue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -795,M36,(systemic disorders of connective tissue in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -796,M40,(kyphosis and lordosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -797,M41,(scoliosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.9,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -798,M42,(spinal osteochondrosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -799,M43,(other deforming dorsopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -800,M45,(ankylosing spondylitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -801,M46,(other inflammatory spondylopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -802,M47,(spondylosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -803,M48,(other spondylopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.5,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -804,M49,(spondylopathies in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -805,M50,(cervical disk disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -806,M51,(other intervertebral disk disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -807,M53,"(other dorsopathies, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -808,M54,(dorsalgia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -809,M60,(myositis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -810,M61,(calcification and ossification of muscle),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -811,M62,(other disorders of muscle),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -812,M63,(disorders of muscle in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -813,M65,(synovitis and tenosynovitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -814,M66,(spontaneous rupture of synovium and tendon),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -815,M67,(other disorders of synovium and tendon),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -816,M68,(disorders of synovium and tendon in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -817,M70,"(soft tissue disorders related to use, overuse and pressure)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -818,M71,(other bursopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -819,M72,(fibroblastic disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -820,M73,(soft tissue disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -821,M75,(shoulder lesions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -822,M76,"(enthesopathies of lower limb, excluding foot)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -823,M77,(other enthesopathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -824,M79,"(other soft tissue disorders, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.1,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -825,M80,(osteoporosis with pathological fracture),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.8,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -826,M81,(osteoporosis without pathological fracture),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -827,M82,(osteoporosis in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -828,M83,(adult osteomalacia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -829,M84,(disorders of continuity of bone),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -830,M85,(other disorders of bone density and structure),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -831,M86,(osteomyelitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -832,M87,(osteonecrosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -833,M88,(paget's disease of bone [osteitis deformans]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -834,M89,(other disorders of bone),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -835,M90,(osteopathies in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -836,M91,(juvenile osteochondrosis of hip and pelvis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -837,M92,(other juvenile osteochondrosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -838,M93,(other osteochondropathies),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -839,M94,(other disorders of cartilage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -840,M95,(other acquired deformities of musculoskeletal system and connective tissue),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -841,M96,"(postprocedural musculoskeletal disorders, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -842,M99,"(biomechanical lesions, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -843,N00,(acute nephritic syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -844,N01,(rapidly progressive nephritic syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -845,N02,(recurrent and persistent haematuria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -846,N03,(chronic nephritic syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -847,N04,(nephrotic syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -848,N05,(unspecified nephritic syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -849,N06,(isolated proteinuria with specified morphological lesion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -850,N07,"(hereditary nephropathy, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -851,N08,(glomerular disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -852,N10,(acute tubulo-interstitial nephritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -853,N11,(chronic tubulo-interstitial nephritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -854,N12,"(tubulo-interstitial nephritis, not specified as acute or chronic)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -855,N13,(obstructive and reflux uropathy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -856,N14,(drug- and heavy-metal-induced tubulo-interstitial and tubular conditions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -857,N15,(other renal tubulo-interstitial diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -858,N16,(renal tubulo-interstitial disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -859,N17,(acute renal failure),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.8,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -860,N18,(chronic renal failure),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.4,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -861,N19,(unspecified renal failure),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.6,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -862,N20,(calculus of kidney and ureter),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.7,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -863,N21,(calculus of lower urinary tract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -864,N22,(calculus of urinary tract in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -865,N23,(unspecified renal colic),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -866,N25,(disorders resulting from impaired renal tubular function),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -867,N26,(unspecified contracted kidney),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -868,N27,(small kidney of unknown cause),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -869,N28,"(other disorders of kidney and ureter, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,1.3,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -870,N29,(other disorders of kidney and ureter in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -871,N30,(cystitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -872,N31,"(neuromuscular dysfunction of bladder, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -873,N32,(other disorders of bladder),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -874,N33,(bladder disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -875,N34,(urethritis and urethral syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -876,N35,(urethral stricture),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -877,N36,(other disorders of urethra),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -878,N37,(urethral disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -879,N39,(other disorders of urinary system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,3.2,Gilbert et al. Lancet 2018 supplementary appendix Table A2,exact_three_character_icd10 -880,N40,(hyperplasia of prostate),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -881,N41,(inflammatory diseases of prostate),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -882,N42,(other disorders of prostate),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -883,N43,(hydrocele and spermatocele),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -884,N44,(torsion of testis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -885,N45,(orchitis and epididymitis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -886,N46,(male infertility),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -887,N47,"(redundant prepuce, phimosis and paraphimosis)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -888,N48,(other disorders of penis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -889,N49,"(inflammatory disorders of male genital organs, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -890,N50,(other disorders of male genital organs),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -891,N51,(disorders of male genital organs in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -892,N60,(benign mammary dysplasia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -893,N61,(inflammatory disorders of breast),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -894,N62,(hypertrophy of breast),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -895,N63,(unspecified lump in breast),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -896,N64,(other disorders of breast),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -897,N70,(salpingitis and oophoritis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -898,N71,"(inflammatory disease of uterus, except cervix)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -899,N72,(inflammatory disease of cervix uteri),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -900,N73,(other female pelvic inflammatory diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -901,N74,(female pelvic inflammatory disorders in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -902,N75,(diseases of bartholin's gland),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -903,N76,(other inflammation of vagina and vulva),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -904,N77,(vulvovaginal ulceration and inflammation in diseases classified elsewhere),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -905,N80,(endometriosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -906,N81,(female genital prolapse),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -907,N82,(fistulae involving female genital tract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -908,N83,"(noninflammatory disorders of ovary, fallopian tube and broad ligament)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -909,N84,(polyp of female genital tract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -910,N85,"(other noninflammatory disorders of uterus, except cervix)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -911,N86,(erosion and ectropion of cervix uteri),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -912,N87,(dysplasia of cervix uteri),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -913,N88,(other noninflammatory disorders of cervix uteri),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -914,N89,(other noninflammatory disorders of vagina),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -915,N90,(other noninflammatory disorders of vulva and perineum),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -916,N91,"(absent, scanty and rare menstruation)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -917,N92,"(excessive, frequent and irregular menstruation)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -918,N93,(other abnormal uterine and vaginal bleeding),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -919,N94,(pain and other conditions associated with female genital organs and menstrual cycle),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -920,N95,(menopausal and other perimenopausal disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -921,N96,(habitual aborter),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -922,N97,(female infertility),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -923,N98,(complications associated with artificial fertilisation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -924,N99,"(postprocedural disorders of genito-urinary system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -925,O00,(ectopic pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -926,O01,(hydatidiform mole),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -927,O02,(other abnormal products of conception),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -928,O03,(spontaneous abortion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -929,O04,(medical abortion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -930,O05,(other abortion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -931,O06,(unspecified abortion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -932,O07,(failed attempted abortion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -933,O08,(complications following abortion and ectopic and molar pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -934,O10,"(pre-existing hypertension complicating pregnancy, childbirth and the puerperium)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -935,O11,(pre-existing hypertensive disorder with superimposed proteinuria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -936,O12,(gestational [pregnancy-induced] oedema and proteinuria without hypertension),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -937,O13,(gestational [pregnancy-induced] hypertension without significant proteinuria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -938,O14,(gestational [pregnancy-induced] hypertension with significant proteinuria),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -939,O15,(eclampsia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -940,O16,(unspecified maternal hypertension),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -941,O20,(haemorrhage in early pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -942,O21,(excessive vomiting in pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -943,O22,(venous complications in pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -944,O23,(infections of genito-urinary tract in pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -945,O24,(diabetes mellitus in pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -946,O25,(malnutrition in pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -947,O26,(maternal care for other conditions predominantly related to pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -948,O28,(abnormal findings on antenatal screening of mother),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -949,O29,(complications of anaesthesia during pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -950,O30,(multiple gestation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -951,O31,(complications specific to multiple gestation),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -952,O32,(maternal care for known or suspected malpresentation of foetus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -953,O33,(maternal care for known or suspected disproportion),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -954,O34,(maternal care for known or suspected abnormality of pelvic organs),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -955,O35,(maternal care for known or suspected foetal abnormality and damage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -956,O36,(maternal care for other known or suspected foetal problems),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -957,O40,(polyhydramnios),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -958,O41,(other disorders of amniotic fluid and membranes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -959,O42,(premature rupture of membranes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -960,O43,(placental disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -961,O44,(placenta praevia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -962,O45,(premature separation of placenta [abruptio placentae]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -963,O46,"(antepartum haemorrhage, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -964,O47,(false labour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -965,O48,(prolonged pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -966,O60,(preterm delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -967,O61,(failed induction of labour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -968,O62,(abnormalities of forces of labour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -969,O63,(long labour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -970,O64,(obstructed labour due to malposition and malpresentation of foetus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -971,O65,(obstructed labour due to maternal pelvic abnormality),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -972,O66,(other obstructed labour),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -973,O67,"(labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -974,O68,(labour and delivery complicated by foetal stress [distress]),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -975,O69,(labour and delivery complicated by umbilical cord complications),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -976,O70,(perineal laceration during delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -977,O71,(other obstetric trauma),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -978,O72,(postpartum haemorrhage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -979,O73,"(retained placenta and membranes, without haemorrhage)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -980,O74,(complications of anaesthesia during labour and delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -981,O75,"(other complications of labour and delivery, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -982,O80,(single spontaneous delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -983,O81,(single delivery by forceps and vacuum extractor),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -984,O82,(single delivery by caesarean section),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -985,O83,(other assisted single delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -986,O84,(multiple delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -987,O85,(puerperal sepsis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -988,O86,(other puerperal infections),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -989,O87,(venous complications in the puerperium),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -990,O88,(obstetric embolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -991,O89,(complications of anaesthesia during the puerperium),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -992,O90,"(complications of the puerperium, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -993,O91,(infections of breast associated with childbirth),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -994,O92,(other disorders of breast and lactation associated with childbirth),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -995,O94,"(sequelae of complication of pregnancy, childbirth and the puerperium)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -996,O96,(death from any obstetric cause occurring more than 42 days but less than one year after delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -997,O98,"(maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -998,O99,"(other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -999,P00,(foetus and newborn affected by maternal conditions that may be unrelated to present pregnancy),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1000,P02,"(foetus and newborn affected by complications of placenta, cord and membranes)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1001,P03,(foetus and newborn affected by other complications of labour and delivery),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1002,P04,(foetus and newborn affected by noxious influences transmitted via placenta or breast milk),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1003,P05,(slow foetal growth and foetal malnutrition),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1004,P07,"(disorders related to short gestation and low birth weight, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1005,P08,(disorders related to long gestation and high birth weight),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1006,P10,(intracranial laceration and haemorrhage due to birth injury),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1007,P11,(other birth injuries to central nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1008,P12,(birth injury to scalp),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1009,P13,(birth injury to skeleton),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1010,P14,(birth injury to peripheral nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1011,P15,(other birth injuries),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1012,P20,(intra-uterine hypoxia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1013,P21,(birth asphyxia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1014,P22,(respiratory distress of newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1015,P23,(congenital pneumonia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1016,P24,(neonatal aspiration syndromes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1017,P25,(interstitial emphysema and related conditions originating in the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1018,P26,(pulmonary haemorrhage originating in the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1019,P27,(chronic respiratory disease originating in the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1020,P28,(other respiratory conditions originating in the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1021,P29,(cardiovascular disorders originating in the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1022,P35,(congenital viral diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1023,P36,(bacterial sepsis of newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1024,P37,(other congenital infectious and parasitic diseases),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1025,P38,(omphalitis of newborn with or without mild haemorrhage),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1026,P39,(other infections specific to the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1027,P50,(foetal blood loss),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1028,P51,(umbilical haemorrhage of newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1029,P52,(intracranial nontraumatic haemorrhage of foetus and newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1030,P53,(haemorrhagic disease of foetus and newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1031,P54,(other neonatal haemorrhages),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1032,P55,(haemolytic disease of foetus and newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1033,P58,(neonatal jaundice due to other excessive haemolysis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1034,P59,(neonatal jaundice from other and unspecified causes),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1035,P61,(other perinatal haematological disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1036,P70,(transitory disorders of carbohydrate metabolism specific to foetus and newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1037,P71,(transitory neonatal disorders of calcium and magnesium metabolism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1038,P78,(other perinatal digestive system disorders),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1039,P83,(other conditions of integument specific to foetus and newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1040,P91,(other disturbances of cerebral status of newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1041,P92,(feeding problems of newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1042,P94,(disorders of muscle tone of newborn),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1043,P95,(foetal death of unspecified cause),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1044,P96,(other conditions originating in the perinatal period),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1045,Q00,(anencephaly and similar malformations),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1046,Q01,(encephalocele),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1047,Q02,(microcephaly),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1048,Q03,(congenital hydrocephalus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1049,Q04,(other congenital malformations of brain),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1050,Q05,(spina bifida),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1051,Q06,(other congenital malformations of spinal cord),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1052,Q07,(other congenital malformations of nervous system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1053,Q10,"(congenital malformations of eyelid, lachrymal apparatus and orbit)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1054,Q11,"(anophthalmos, microphthalmos and macrophthalmos)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1055,Q12,(congenital lens malformations),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1056,Q13,(congenital malformations of anterior segment of eye),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1057,Q14,(congenital malformations of posterior segment of eye),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1058,Q15,(other congenital malformations of eye),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1059,Q16,(congenital malformations of ear causing impairment of hearing),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1060,Q17,(other congenital malformations of ear),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1061,Q18,(other congenital malformations of face and neck),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1062,Q20,(congenital malformations of cardiac chambers and connexions),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1063,Q21,(congenital malformations of cardiac septa),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1064,Q22,(congenital malformations of pulmonary and tricuspid valves),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1065,Q23,(congenital malformations of aortic and mitral valves),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1066,Q24,(other congenital malformations of heart),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1067,Q25,(congenital malformations of great arteries),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1068,Q26,(congenital malformations of great veins),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1069,Q27,(other congenital malformations of peripheral vascular system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1070,Q28,(other congenital malformations of circulatory system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1071,Q30,(congenital malformations of nose),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1072,Q31,(congenital malformations of larynx),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1073,Q32,(congenital malformations of trachea and bronchus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1074,Q33,(congenital malformations of lung),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1075,Q34,(other congenital malformations of respiratory system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1076,Q35,(cleft palate),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1077,Q36,(cleft lip),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1078,Q37,(cleft palate with cleft lip),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1079,Q38,"(other congenital malformations of tongue, mouth and pharynx)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1080,Q39,(congenital malformations of oesophagus),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1081,Q40,(other congenital malformations of upper alimentary tract),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1082,Q41,"(congenital absence, atresia and stenosis of small intestine)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1083,Q42,"(congenital absence, atresia and stenosis of large intestine)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1084,Q43,(other congenital malformations of intestine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1085,Q44,"(congenital malformations of gallbladder, bile ducts and liver)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1086,Q45,(other congenital malformations of digestive system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1087,Q50,"(congenital malformations of ovaries, fallopian tubes and broad ligaments)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1088,Q51,(congenital malformations of uterus and cervix),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1089,Q52,(other congenital malformations of female genitalia),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1090,Q53,(undescended testicle),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1091,Q54,(hypospadias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1092,Q55,(other congenital malformations of male genital organs),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1093,Q56,(indeterminate sex and pseudohermaphroditism),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1094,Q60,(renal agenesis and other reduction defects of kidney),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1095,Q61,(cystic kidney disease),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1096,Q62,(congenital obstructive defects of renal pelvis and congenital malformations of ureter),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1097,Q63,(other congenital malformations of kidney),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1098,Q64,(other congenital malformations of urinary system),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1099,Q65,(congenital deformities of hip),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1100,Q66,(congenital deformities of feet),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1101,Q67,"(congenital musculoskeletal deformities of head, face, spine and chest)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1102,Q68,(other congenital musculoskeletal deformities),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1103,Q69,(polydactyly),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1104,Q70,(syndactyly),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1105,Q71,(reduction defects of upper limb),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1106,Q72,(reduction defects of lower limb),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1107,Q73,(reduction defects of unspecified limb),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1108,Q74,(other congenital malformations of limb(s)),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1109,Q75,(other congenital malformations of skull and face bones),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1110,Q76,(congenital malformations of spine and bony thorax),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1111,Q77,(osteochondrodysplasia with defects of growth of tubular bones and spine),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1112,Q78,(other osteochondrodysplasias),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1113,Q79,"(congenital malformations of musculoskeletal system, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1114,Q80,(congenital ichthyosis),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1115,Q81,(epidermolysis bullosa),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1116,Q82,(other congenital malformations of skin),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1117,Q83,(congenital malformations of breast),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1118,Q84,(other congenital malformations of integument),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1119,Q85,"(phakomatoses, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1120,Q86,"(congenital malformation syndromes due to known exogenous causes, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1121,Q87,(other specified congenital malformation syndromes affecting multiple systems),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1122,Q89,"(other congenital malformations, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1123,Q90,(down's syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1124,Q91,(edwards' syndrome and patau's syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1125,Q92,"(other trisomies and partial trisomies of the autosomes, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1126,Q93,"(monosomies and deletions from the autosomes, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1127,Q95,"(balanced rearrangements and structural markers, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1128,Q96,(turner's syndrome),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1129,Q97,"(other sex chromosome abnormalities, female phenotype, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1130,Q98,"(other sex chromosome abnormalities, male phenotype, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1131,Q99,"(other chromosome abnormalities, not elsewhere classified)",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1132,CXX,Unknown Cancer,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1133,C00,Malignant neoplasm of lip,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1134,C01,Malignant neoplasm of base of tongue,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1135,C02,Malignant neoplasm of other and unspecified parts of tongue,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1136,C03,Malignant neoplasm of gum,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1137,C04,Malignant neoplasm of floor of mouth,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1138,C05,Malignant neoplasm of palate,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1139,C06,Malignant neoplasm of other and unspecified parts of mouth,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1140,C07,Malignant neoplasm of parotid gland,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1141,C08,Malignant neoplasm of other and unspecified major salivary glands,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1142,C09,Malignant neoplasm of tonsil,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1143,C10,Malignant neoplasm of oropharynx,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1144,C11,Malignant neoplasm of nasopharynx,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1145,C12,Malignant neoplasm of pyriform sinus,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1146,C13,Malignant neoplasm of hypopharynx,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1147,C14,"Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1148,C15,Malignant neoplasm of oesophagus,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1149,C16,Malignant neoplasm of stomach,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1150,C17,Malignant neoplasm of small intestine,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1151,C18,Malignant neoplasm of colon,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1152,C19,Malignant neoplasm of rectosigmoid junction,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1153,C20,Malignant neoplasm of rectum,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1154,C21,Malignant neoplasm of anus and anal canal,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1155,C22,Malignant neoplasm of liver and intrahepatic bile ducts,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1156,C23,Malignant neoplasm of gallbladder,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1157,C24,Malignant neoplasm of other and unspecified parts of biliary tract,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1158,C25,Malignant neoplasm of pancreas,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1159,C26,Malignant neoplasm of other and ill-defined digestive organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1160,C30,Malignant neoplasm of nasal cavity and middle ear,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1161,C31,Malignant neoplasm of accessory sinuses,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1162,C32,Malignant neoplasm of larynx,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1163,C33,Malignant neoplasm of trachea,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1164,C34,Malignant neoplasm of bronchus and lung,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1165,C37,Malignant neoplasm of thymus,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1166,C38,"Malignant neoplasm of heart, mediastinum and pleura",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1167,C39,Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1168,C40,Malignant neoplasm of bone and articular cartilage of limbs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1169,C41,Malignant neoplasm of bone and articular cartilage of other and unspecified sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1170,C42,hematopoietic and reticuloendothelial systems (ICD-O-3 specific),hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1171,C43,Malignant melanoma of skin,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1172,C44,Other malignant neoplasms of skin,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1173,C45,Mesothelioma,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1174,C46,Kaposi's sarcoma,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1175,C47,Malignant neoplasm of peripheral nerves and autonomic nervous system,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1176,C48,Malignant neoplasm of retroperitoneum and peritoneum,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1177,C49,Malignant neoplasm of other connective and soft tissue,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1178,C50,Malignant neoplasm of breast,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1179,C51,Malignant neoplasm of vulva,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1180,C52,Malignant neoplasm of vagina,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1181,C53,Malignant neoplasm of cervix uteri,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1182,C54,Malignant neoplasm of corpus uteri,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1183,C55,"Malignant neoplasm of uterus, part unspecified",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1184,C56,Malignant neoplasm of ovary,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1185,C57,Malignant neoplasm of other and unspecified female genital organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1186,C58,Malignant neoplasm of placenta,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1187,C60,Malignant neoplasm of penis,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1188,C61,Malignant neoplasm of prostate,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1189,C62,Malignant neoplasm of testis,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1190,C63,Malignant neoplasm of other and unspecified male genital organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1191,C64,"Malignant neoplasm of kidney, except renal pelvis",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1192,C65,Malignant neoplasm of renal pelvis,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1193,C66,Malignant neoplasm of ureter,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1194,C67,Malignant neoplasm of bladder,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1195,C68,Malignant neoplasm of other and unspecified urinary organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1196,C69,Malignant neoplasm of eye and adnexa,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1197,C70,Malignant neoplasm of meninges,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1198,C71,Malignant neoplasm of brain,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1199,C72,"Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1200,C73,Malignant neoplasm of thyroid gland,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1201,C74,Malignant neoplasm of adrenal gland,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1202,C75,Malignant neoplasm of other endocrine glands and related structures,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1203,C76,Malignant neoplasm of other and ill-defined sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1204,C77,Secondary and unspecified malignant neoplasm of lymph nodes,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1205,C78,Secondary malignant neoplasm of respiratory and digestive organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1206,C79,Secondary malignant neoplasm of other sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1207,C80,Malignant neoplasm without specification of site,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1208,C81,Hodgkin's disease,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1209,C82,Follicular [nodular] non-Hodgkin's lymphoma,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1210,C83,Diffuse non-Hodgkin's lymphoma,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1211,C84,Peripheral and cutaneous T-cell lymphomas,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1212,C85,Other and unspecified types of non-Hodgkin's lymphoma,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1213,C86,Other specified types of T/NK-cell lymphoma,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1214,C88,Malignant immunoproliferative diseases,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1215,C90,Multiple myeloma and malignant plasma cell neoplasms,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1216,C91,Lymphoid leukaemia,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1217,C92,Myeloid leukaemia,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1218,C93,Monocytic leukaemia,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1219,C94,Other leukaemias of specified cell type,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1220,C95,Leukaemia of unspecified cell type,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1221,C96,"Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1222,C97,Malignant neoplasms of independent (primary) multiple sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1223,D00,"Carcinoma in situ of oral cavity, oesophagus and stomach",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1224,D01,Carcinoma in situ of other and unspecified digestive organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1225,D02,Carcinoma in situ of middle ear and respiratory system,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1226,D03,Melanoma in situ,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1227,D04,Carcinoma in situ of skin,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1228,D05,Carcinoma in situ of breast,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1229,D06,Carcinoma in situ of cervix uteri,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1230,D07,Carcinoma in situ of other and unspecified genital organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1231,D09,Carcinoma in situ of other and unspecified sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1232,D10,Benign neoplasm of mouth and pharynx,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1233,D11,Benign neoplasm of major salivary glands,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1234,D12,"Benign neoplasm of colon, rectum, anus and anal canal",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1235,D13,Benign neoplasm of other and ill-defined parts of digestive system,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1236,D15,Benign neoplasm of other and unspecified intrathoracic organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1237,D16,Benign neoplasm of bone and articular cartilage,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1238,D18,"Haemangioma and lymphangioma, any site",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1239,D27,Benign neoplasm of ovary,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1240,D30,Benign neoplasm of urinary organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1241,D32,Benign neoplasm of meninges,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1242,D33,Benign neoplasm of brain and other parts of central nervous system,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1243,D34,Benign neoplasm of thyroid gland,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1244,D35,Benign neoplasm of other and unspecified endocrine glands,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1245,D36,Benign neoplasm of other and unspecified sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1246,D37,Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1247,D38,Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1248,D39,Neoplasm of uncertain or unknown behaviour of female genital organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1249,D40,Neoplasm of uncertain or unknown behaviour of male genital organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1250,D41,Neoplasm of uncertain or unknown behaviour of urinary organs,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1251,D42,Neoplasm of uncertain or unknown behaviour of meninges,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1252,D43,Neoplasm of uncertain or unknown behaviour of brain and central nervous system,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1253,D44,Neoplasm of uncertain or unknown behaviour of endocrine glands,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1254,D45,Polycythaemia vera,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1255,D46,Myelodysplastic syndromes,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1256,D47,"Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue",hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1257,D48,Neoplasm of uncertain or unknown behaviour of other and unspecified sites,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs -1258,DEATH,,hfrs_weighted_disease_expression,DeepHealth HFRS-weighted disease expression,UK-HFRS,0.0,Gilbert et al. Lancet 2018 supplementary appendix Table A2,not_in_hfrs diff --git a/uk_hfrs_missing_label_codes.csv b/uk_hfrs_missing_label_codes.csv deleted file mode 100644 index 3d176ee..0000000 --- a/uk_hfrs_missing_label_codes.csv +++ /dev/null @@ -1,53 +0,0 @@ -hfrs_source_code,hfrs_weight,missing_reason,hfrs_source -R00,0.7,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R02,1.0,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R11,0.3,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R13,0.8,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R26,2.6,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R29,3.6,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R31,3.0,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R32,1.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R33,1.3,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R40,2.5,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R41,2.7,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R44,1.6,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R45,1.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R47,1.0,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R50,0.1,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R54,2.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R55,1.8,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R56,2.6,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R63,0.9,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R69,1.3,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R79,0.6,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -R94,1.4,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -S00,3.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -S01,1.1,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -S06,2.4,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -S09,1.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -S22,1.8,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -S32,1.4,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -S42,2.3,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -S51,0.5,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -S72,1.4,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -S80,2.0,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -T83,2.4,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -U80,0.8,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -W01,0.9,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -W06,1.1,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -W10,0.9,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -W18,2.1,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -W19,3.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -X59,1.5,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -Y84,0.7,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -Y95,1.2,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -Z22,1.7,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -Z50,2.1,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -Z60,1.8,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -Z73,0.6,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -Z74,1.1,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -Z75,2.0,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -Z87,1.5,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -Z91,0.5,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -Z93,1.0,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2 -Z99,0.8,not_present_in_labels_csv,Gilbert et al. Lancet 2018 supplementary appendix Table A2