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DeepHealth/build_organ_involvement_label_mapping.py

158 lines
4.7 KiB
Python

from __future__ import annotations
import csv
import re
from pathlib import Path
LABELS = Path("labels.csv")
OUT = Path("organ_involvement_label_mapping.csv")
ORGANS = [
"brain_neurologic",
"heart",
"artery_vascular",
"immune",
"intestine_digestive",
"kidney",
"liver",
"lung",
"muscle_musculoskeletal",
"pancreas_endocrine",
"adipose_metabolic",
"female_reproductive",
"male_reproductive",
"neoplasm",
]
def _code_key(code: str) -> tuple[str, int, str]:
code = code.strip().upper()
match = re.match(r"^([A-Z])(\d{2})(?:\.?([A-Z0-9]+))?", code)
if not match:
raise ValueError(f"Invalid ICD-10 code: {code!r}")
letter, number, suffix = match.groups()
return letter, int(number), suffix or ""
def _in_range(code: str, start: str, end: str) -> bool:
c_letter, c_num, _ = _code_key(code)
s_letter, s_num, _ = _code_key(start)
e_letter, e_num, _ = _code_key(end)
if s_letter == e_letter:
return c_letter == s_letter and s_num <= c_num <= e_num
return (
(s_letter < c_letter < e_letter)
or (c_letter == s_letter and c_num >= s_num)
or (c_letter == e_letter and c_num <= e_num)
)
def _matches_any(code: str, ranges: list[tuple[str, str]]) -> bool:
return any(_in_range(code, start, end) for start, end in ranges)
def organ_for_icd10(code: str) -> tuple[str, str]:
code = code.strip().upper()
if not re.match(r"^[A-Z]\d{2}", code):
return "", "unmapped_non_icd10"
if _matches_any(code, [("C00", "D48")]):
return "neoplasm", "neoplasm_c00_d48"
if _matches_any(code, [("F00", "F09"), ("G00", "G99"), ("I60", "I69")]):
return "brain_neurologic", "f00_f09_g00_g99_i60_i69"
if _matches_any(code, [("I00", "I09"), ("I20", "I52")]):
return "heart", "i00_i09_i20_i52"
if _matches_any(code, [("I10", "I15"), ("I70", "I89"), ("I95", "I99")]):
return "artery_vascular", "i10_i15_i70_i89_i95_i99"
if _matches_any(code, [("A00", "B99"), ("D50", "D89")]):
return "immune", "a00_b99_d50_d89"
if _matches_any(code, [("J00", "J99")]):
return "lung", "j00_j99"
if _matches_any(code, [("K70", "K77")]):
return "liver", "k70_k77"
if _matches_any(code, [("K85", "K86"), ("E10", "E16")]):
return "pancreas_endocrine", "k85_k86_e10_e16"
if _matches_any(code, [("K00", "K69"), ("K78", "K84"), ("K87", "K93")]):
return "intestine_digestive", "k00_k69_k78_k84_k87_k93"
if _matches_any(code, [("N00", "N39")]):
return "kidney", "n00_n39"
if _matches_any(code, [("N70", "N98"), ("O00", "O99")]):
return "female_reproductive", "n70_n98_o00_o99"
if _matches_any(code, [("N40", "N53")]):
return "male_reproductive", "n40_n53"
if _matches_any(code, [("M00", "M99")]):
return "muscle_musculoskeletal", "m00_m99"
if _matches_any(code, [("E00", "E09"), ("E17", "E90")]):
return "adipose_metabolic", "e00_e09_e17_e90"
return "", "unmapped_no_organ_rule"
def main() -> None:
rows = []
with LABELS.open(encoding="utf-8") as f:
for i, line in enumerate(f):
line = line.strip()
if not line:
continue
parts = line.split(maxsplit=1)
code = parts[0].strip().upper()
name = parts[1].strip() if len(parts) > 1 else ""
organ_id, match_source = organ_for_icd10(code)
rows.append(
{
"token_id": i + 3,
"label_code": code,
"label_name": name,
"organ_id": organ_id,
"organ_label": organ_id,
"organ_weight": 1.0 if organ_id else 0.0,
"match_source": match_source,
"mapping_source": (
"organ-age-inspired clinical systems based on "
"Oh et al. Nature 2023; single-label ICD-10 rules"
),
}
)
fieldnames = [
"token_id",
"label_code",
"label_name",
"organ_id",
"organ_label",
"organ_weight",
"match_source",
"mapping_source",
]
with OUT.open("w", newline="", encoding="utf-8-sig") as f:
writer = csv.DictWriter(f, fieldnames=fieldnames)
writer.writeheader()
writer.writerows(rows)
mapped = [row for row in rows if row["organ_id"]]
print(f"labels: {len(rows)}")
print(f"mapped_labels: {len(mapped)}")
print(f"unmapped_labels: {len(rows) - len(mapped)}")
print(f"organs: {', '.join(ORGANS)}")
print(f"output: {OUT}")
if __name__ == "__main__":
main()